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2025

Journal Article

The Phoenix Sepsis Score in Pediatric Oncology Patients With Sepsis at PICU Admission: Test of Performance in a European Multicenter Cohort, 2018–2020

Wösten-van Asperen, Roelie M., la Roi-Teeuw, Hannah M., Tissing, Wim J.E., Jordan, Iolanda, Dohna-Schwake, Christian, Bottari, Gabriella, Pappachan, John, Crazzolara, Roman, Amigoni, Angela, Mizia-Malarz, Agnieszka, Moscatelli, Andrea, Sánchez-Martín, María, Willems, Jef, Schlapbach, Luregn J. and on behalf of PICU Oncology Kids in Europe Research (POKER) group research consortium of European Society for Paediatric and Neonatal Intensive Care (ESPNIC) (2025). The Phoenix Sepsis Score in Pediatric Oncology Patients With Sepsis at PICU Admission: Test of Performance in a European Multicenter Cohort, 2018–2020. Pediatric Critical Care Medicine, 26 (2), e177-e185. doi: 10.1097/pcc.0000000000003683

The Phoenix Sepsis Score in Pediatric Oncology Patients With Sepsis at PICU Admission: Test of Performance in a European Multicenter Cohort, 2018–2020

2025

Journal Article

A diagnostic host-specific transcriptome response for Mycoplasma pneumoniae pneumonia to guide pediatric patient treatment

Viz-Lasheras, Sandra, Gómez-Carballa, Alberto, Bello, Xabier, Rivero-Calle, Irene, Dacosta, Ana Isabel, Kaforou, Myrsini, Habgood-Coote, Dominic, Cunnington, Aubrey J., Emonts, Marieke, Herberg, Jethro A., Wright, Victoria J., Carrol, Enitan D., Paulus, Stephane C., Zenz, Werner, Kohlfürst, Daniela S., Schweintzger, Nina, Van der Flier, Michiel, de Groot, Ronald, Schlapbach, Luregn J., Agyeman, Philipp, Pollard, Andrew J., Fink, Colin, Kuijpers, Taco T., Anderson, Suzanne, Von Both, Ulrich, Pokorn, Marko, Zavadska, Dace, Tsolia, María, Moll, Henriëtte A ... Salas, Antonio (2025). A diagnostic host-specific transcriptome response for Mycoplasma pneumoniae pneumonia to guide pediatric patient treatment. Nature Communications, 16 (1) 673, 1-13. doi: 10.1038/s41467-025-55932-9

A diagnostic host-specific transcriptome response for Mycoplasma pneumoniae pneumonia to guide pediatric patient treatment

2025

Journal Article

Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric Sepsis

Gilholm, Patricia, Lister, Paula, Irwin, Adam, Harley, Amanda, Raman, Sainath, Schlapbach, Luregn J. and Gibbons, Kristen S. (2025). Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric Sepsis. Maternal and Child Health Journal, 29 (5), 1-10. doi: 10.1007/s10995-025-04038-1

Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric Sepsis

2025

Journal Article

Genetic determinants of the complement and coagulation pathways in invasive meningococcal disease

Bellos, Evangelos, van Leeuwen, Karin, Duret, Amedine, Hodeib, Stephanie, Mashbat, Meg, Kohlfuerst, Daniela S., Boeddha, Navin P., Schlapbach, Luregn J., Wright, Victoria J., Fink, Colin G., van der Flier, Michiel, van Deuren, Marcel, Sprong, Tom, López-Trascasa, Margarita, López-Lera, Alberto, Martinón-Torres, Federico, Salas, Antonio, Santillo, Dilys, Zenz, Werner, Driessen, Gertjan J., Anderson, Suzanne T., Secka, Fatou, Paulus, Stephane, de Groot, Ronald, Emonts, Marieke, Carrol, Enitan D., Herberg, Jethro, Levin, Mike, Sancho-Shimizu, Vanessa and Kuijpers, Taco (2025). Genetic determinants of the complement and coagulation pathways in invasive meningococcal disease. Journal of Allergy and Clinical Immunology. doi: 10.1016/j.jaci.2025.09.011

Genetic determinants of the complement and coagulation pathways in invasive meningococcal disease

2025

Journal Article

Comparison of carbon dioxide control during pressure controlled versus pressure-regulated volume controlled ventilation in children (CoCO2): protocol for a pilot digital randomised controlled trial in a quaternary paediatric intensive care unit

Mozun, Rebeca, Chopard, Daphné, Zapf, Florian, Baumann, Philipp, Brotschi, Barbara, Adam, Anika, Jaeggi, Vera, Bangerter, Beat, Gibbons, Kristen S., Burren, Juerg and Schlapbach, Luregn J. (2025). Comparison of carbon dioxide control during pressure controlled versus pressure-regulated volume controlled ventilation in children (CoCO2): protocol for a pilot digital randomised controlled trial in a quaternary paediatric intensive care unit. BMJ Open, 15 (1) e087043, 1-9. doi: 10.1136/bmjopen-2024-087043

Comparison of carbon dioxide control during pressure controlled versus pressure-regulated volume controlled ventilation in children (CoCO2): protocol for a pilot digital randomised controlled trial in a quaternary paediatric intensive care unit

2025

Journal Article

The Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG): 20 years of collaborative research

Gibbons, Kristen S., Beca, John, Delzoppo, Carmel, Erickson, Simon, Festa, Marino, Gelbart, Ben, Long, Debbie, Masterson, Kate, Millar, Johnny, Raman, Sainath, Schlapbach, Luregn J., Butt, Warwick and on behalf of the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2025). The Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG): 20 years of collaborative research. Pediatric Critical Care Medicine, 26 (1), e122-e130. doi: 10.1097/pcc.0000000000003653

The Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG): 20 years of collaborative research

2024

Journal Article

Resuscitation in Paediatric Septic Shock Using Vitamin C and Hydrocortisone (RESPOND): the RESPOND Randomized Controlled Trial Protocol

Raman, Sainath, Gibbons, Kristen S., Jayashree, Muralidharan, Lalitha, AV, Bellomo, Rinaldo, Blythe, Robin, Buckley, David, Butt, Warwick, Cho, Hwa Jin, Cree, Michele, de Souza, Daniela C., Erickson, Simon, Festa, Marino, Ganu, Subodh, George, Shane, James, Ebor Jacob, Johnson, Kerry, Le Marsney, Renate, Lister, Paula, Pham, Trang M. T., Singh, Puneet, Venkatesh, Balasubramanian, Wall, Renee, Long, Debbie A., Schlapbach, Luregn J. and on behalf of the Resuscitation in Paediatric Septic Shock using Vitamin C and Hydrocortisone (RESPOND) Study Group and the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2024). Resuscitation in Paediatric Septic Shock Using Vitamin C and Hydrocortisone (RESPOND): the RESPOND Randomized Controlled Trial Protocol. Pediatric Critical Care Medicine, 26 (3), 1-12. doi: 10.1097/pcc.0000000000003674

Resuscitation in Paediatric Septic Shock Using Vitamin C and Hydrocortisone (RESPOND): the RESPOND Randomized Controlled Trial Protocol

2024

Journal Article

Paediatric Personalized Research Network Switzerland (SwissPedHealth): a joint paediatric national data stream 

Mozun, Rebeca, Belle, Fabien N., Agostini, Andrea, Baumgartner, Matthias R., Fellay, Jacques, Forrest, Christopher B., Froese, D. Sean, Giannoni, Eric, Goetze, Sandra, Hofmann, Kathrin, Latzin, Philipp, Lauener, Roger, Martin Necker, Aurelie, Ormond, Kelly, Pachlopnik Schmid, Jana, Pedrioli, Patrick G. A., Posfay-Barbe, Klara M., Rauch, Anita, Schulzke, Sven, Stocker, Martin, Spycher, Ben D., Vayena, Effy, Welzel, Tatjana, Zamboni, Nicola, Vogt, Julia E., Schlapbach, Luregn J., Bielicki, Julia A., Kuehni, Claudia E. and SwissPedHealth Consortium, (2024). Paediatric Personalized Research Network Switzerland (SwissPedHealth): a joint paediatric national data stream . Bmj Open, 14 (12) e091884. doi: 10.1136/bmjopen-2024-091884

Paediatric Personalized Research Network Switzerland (SwissPedHealth): a joint paediatric national data stream 

2024

Journal Article

Mental health in children admitted with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): a follow-up study at 6 months of the Swissped-RECOVERY trial

Schöbi, Nina, Sanchez, Carlos, Atkinson, Andrew, Andre, Maya C., Blanchard-Rohner, Geraldine, Perez, Maria-Helena, Trück, Johannes, Welzel, Tatjana, Schlapbach, Luregn J., Bielicki, Julia and Grazioli, Serge (2024). Mental health in children admitted with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): a follow-up study at 6 months of the Swissped-RECOVERY trial. Intensive Care Medicine – Paediatric and Neonatal, 2 (1) 34, 1-9. doi: 10.1007/s44253-024-00057-y

Mental health in children admitted with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): a follow-up study at 6 months of the Swissped-RECOVERY trial

2024

Journal Article

Serum sodium concentration during arginine vasopressin infusion in critically ill children

Muff, Rafael, Gotta, Verena, Jaeggi, Vera, Schlapbach, Luregn J. and Baumann, Philipp (2024). Serum sodium concentration during arginine vasopressin infusion in critically ill children. Children, 11 (11) 1359, 1-10. doi: 10.3390/children11111359

Serum sodium concentration during arginine vasopressin infusion in critically ill children

2024

Journal Article

The impact of extracorporeal support on antimicrobial pharmacokinetics in critically ill neonatal and paediatric patients: a systematic review

Cree, Michele L., Abdul-Aziz, Mohd Hafiz, Schlapbach, Luregn J., Roberts, Jason A. and Parker, Suzanne (2024). The impact of extracorporeal support on antimicrobial pharmacokinetics in critically ill neonatal and paediatric patients: a systematic review. International Journal of Antimicrobial Agents, 64 (4) 107311, 1-16. doi: 10.1016/j.ijantimicag.2024.107311

The impact of extracorporeal support on antimicrobial pharmacokinetics in critically ill neonatal and paediatric patients: a systematic review

2024

Journal Article

Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomes

Wen, Sophie C. H., Harris, Patrick N. A., Forde, Brian, Permana, Budi, Chatfield, Mark D., Lau, Colleen L., Spurling, Geoffrey, Bauer, Michelle J., Balch, Ross, Chambers, Henry, Schlapbach, Luregn J., Clark, Julia E., Dougherty, Sonia, Blyth, Christopher C., Britton, Philip N., Clifford, Vanessa, Haeusler, Gabrielle M., McMullan, Brendan, Wadia, Ushma, Paterson, David L., Irwin, Adam D., on behalf of the PAEDS network, Carr, Jeremy, Vasilunas, Nan, Francis, Joshua R., Macartney, Kristine, Crawford, Nigel W., Wood, Nicholas, Buttery, Jim ... Glover, Catherine (2024). Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomes. Clinical Infectious Diseases, 79 (3), 734-743. doi: 10.1093/cid/ciae341

Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomes

2024

Journal Article

The authors reply:

Raman, Sainath, Gibbons, Kristen, LeMarsney, Renate and Schlapbach, Luregn J. (2024). The authors reply:. Pediatric Critical Care Medicine, 25 (9), e398-e399. doi: 10.1097/pcc.0000000000003578

The authors reply:

2024

Journal Article

Quality improvement programmes in paediatric sepsis from a global perspective

de Souza, Daniela C., Paul, Raina, Mozun, Rebeca, Sankar, Jhuma, Jabornisky, Roberto, Lim, Emma, Harley, Amanda, Al Amri, Samirah, Aljuaid, Maha, Qian, Suyun, Schlapbach, Luregn J., Argent, Andrew and Kissoon, Niranjan (2024). Quality improvement programmes in paediatric sepsis from a global perspective. The Lancet Child and Adolescent Health, 8 (9), 695-706. doi: 10.1016/S2352-4642(24)00142-1

Quality improvement programmes in paediatric sepsis from a global perspective

2024

Journal Article

Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world

Sanchez-Pinto, L. Nelson, del Pilar Arias López, María, Scott, Halden, Gibbons, Kristen, Moor, Michael, Watson, R. Scott, Wiens, Matthew O., Schlapbach, Luregn J. and Bennett, Tellen D. (2024). Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world. The Lancet Digital Health, 6 (9), e651-e661. doi: 10.1016/s2589-7500(24)00141-9

Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world

2024

Journal Article

The burden and contemporary epidemiology of sepsis in children

Watson, R. Scott, Carrol, Enitan D., Carter, Michael J., Kissoon, Niranjan, Ranjit, Suchitra and Schlapbach, Luregn J. (2024). The burden and contemporary epidemiology of sepsis in children. The Lancet Child and Adolescent Health, 8 (9), 670-681. doi: 10.1016/S2352-4642(24)00140-8

The burden and contemporary epidemiology of sepsis in children

2024

Journal Article

Susceptibility to childhood sepsis, contemporary management, and future directions

Carter, Michael J., Carrol, Enitan D., Ranjit, Suchitra, Mozun, Rebeca, Kissoon, Niranjan, Watson, R. Scott and Schlapbach, Luregn J. (2024). Susceptibility to childhood sepsis, contemporary management, and future directions. The Lancet Child and Adolescent Health, 8 (9), 682-694. doi: 10.1016/S2352-4642(24)00141-X

Susceptibility to childhood sepsis, contemporary management, and future directions

2024

Journal Article

Sex differences in pediatric sepsis—a systematic review protocol

Kennedy, Uchenna, Moulin, Juliette, Schlapbach, Luregn J., Menon, Kusum, Lee, Jan Hau and Held, Ulrike (2024). Sex differences in pediatric sepsis—a systematic review protocol. Systematic Reviews, 13 (1) 214, 1-5. doi: 10.1186/s13643-024-02631-z

Sex differences in pediatric sepsis—a systematic review protocol

2024

Journal Article

Sepsis shapes the human γδ TCR repertoire in an age- and pathogen-dependent manner

Giannoni, Eric, Sanchez Sanchez, Guillem, Verdebout, Isoline, Papadopoulou, Maria, Rezwani, Moosa, Ahmed, Raya, Ladell, Kristin, Miners, Kelly L., McLaren, James E., Fraser, Donald J., Price, David A., Eberl, Matthias, Agyeman, Philipp K. A., Schlapbach, Luregn J and Vermijlen, David (2024). Sepsis shapes the human γδ TCR repertoire in an age- and pathogen-dependent manner. European Journal of Immunology, 54 (10) 2451190, e2451190. doi: 10.1002/eji.202451190

Sepsis shapes the human γδ TCR repertoire in an age- and pathogen-dependent manner

2024

Journal Article

Antibiotic exposure of critically ill children at a tertiary care paediatric intensive care unit in Switzerland

Fenner, Anica, Huber, Melanie, Gotta, Verena, Jaeggi, Vera, Schlapbach, Luregn J. and Baumann, Philipp (2024). Antibiotic exposure of critically ill children at a tertiary care paediatric intensive care unit in Switzerland. Children, 11 (6) 731, 731. doi: 10.3390/children11060731

Antibiotic exposure of critically ill children at a tertiary care paediatric intensive care unit in Switzerland