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Professor Grant Montgomery
Professor

Grant Montgomery

Email: 
Phone: 
+61 7 334 62612

Overview

Background

Professor Grant Montgomery FAHMS FSRB Hon FRSNZ

Professor Montgomery was born in New Zealand, completed PhD studies in Animal Science at Massey University and post-doctoral research in France. In 1987, he co-founded the New Zealand Sheep Genomics Program in the Biochemistry Department at the University of Otago and pioneered the introduction of genome mapping methods in farm animals. He moved to Australia in 1999 and joined the Queensland Institute of Medical Research where he ran a successful genome mapping program for human complex disease. In 2016, he moved to the University of Queensland and holds joint appointments at the Institute for Molecular Bioscience (IMB) and the Queensland Brain Institute (QBI). He is a National Health and Medical Research Council Leadership Fellow and Director of the UQ Genome Innovation Hub. He was elected a Fellow the Society for Reproductive Biology in 2012, Fellow of the Australian Academy of Health and Medical Sciences in 2015, and Honorary Fellow of the Royal Society of New Zealand in 2016. His research focusses on discovery of critical genes and pathways increasing risk for common diseases especially reproductive diseases including endometriosis.

Availability

Professor Grant Montgomery is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, Massey University

Research impacts

Professor Montgomery has made substantial contributions to the worldwide effort to map genomic regions contributing to risk for complex traits and diseases, including endometriosis, age at menarche and menopause, cancers of the reproductive tract, melanoma and inflammatory bowel disease. He is conducting systems genetics and functional studies to identify the genes and pathways affected by these genetic risk factors. His work has identified possible target genes and functional consequences of genetic risk factors in genomic regions associated with endometriosis providing novel insights into the causes of this important disease. He lead a consortium of leading endometriosis clinicians and researchers in Australia awarded a MRFF Frontiers in Health and Medical Science to develop earlier diagnosis and personalised treatments for endometriosis. He is co-leader of International Endometriois Genetics Consortium, Patron of the Endometriosis Association (QLD) Inc (QENDO) and has worked closely with QENDO, other patient groups, clinicians and politicians to help develop the National Action Plan for Endometriosis. He is on the Executive Committee of the National Endometriosis Clinical and Scientific Trials (NECST) Network. He is also Director of the UQ Genome Innovation Hub developing novel methods and pipelines for genomics in health and agriculature that can be widely applied in programs across The University of Queensland.

Works

Search Professor Grant Montgomery’s works on UQ eSpace

841 works between 1978 and 2024

81 - 100 of 841 works

2022

Conference Publication

Comparison of Organoids from Menstrual Fluid and Endometrium from Women Taking Hormonal Medication: Potential for Modelling Endometriosis

Filby, Caitlin E., Wyatt, Katherine A., Mortlock, Sally, Cousins, Fiona L., McKinnon, Brett, Tyson, Kate, Montgomery, Grant W. and Gargett, Caroline E. (2022). Comparison of Organoids from Menstrual Fluid and Endometrium from Women Taking Hormonal Medication: Potential for Modelling Endometriosis. 69th Annual Meeting of the Society for Reproductive Investigation SRI 2022, Denver, CO United States, 15-19 March 2022. Heidelberg, Germany: Springer.

Comparison of Organoids from Menstrual Fluid and Endometrium from Women Taking Hormonal Medication: Potential for Modelling Endometriosis

2022

Journal Article

Body mass index and the diagnosis of endometriosis: findings from a national data linkage cohort study

Rowlands, Ingrid J., Hockey, Richard, Abbott, Jason A., Montgomery, Grant W. and Mishra, Gita D. (2022). Body mass index and the diagnosis of endometriosis: findings from a national data linkage cohort study. Obesity Research and Clinical Practice, 16 (3), 235-241. doi: 10.1016/j.orcp.2022.04.002

Body mass index and the diagnosis of endometriosis: findings from a national data linkage cohort study

2021

Journal Article

Comparison of organoids from menstrual fluid and hormone-treated endometrium: novel tools for gynecological research

Filby, Caitlin E., Wyatt, Katherine A., Mortlock, Sally, Cousins, Fiona L., McKinnon, Brett, Tyson, Kate E., Montgomery, Grant W. and Gargett, Caroline E. (2021). Comparison of organoids from menstrual fluid and hormone-treated endometrium: novel tools for gynecological research. Journal of Personalized Medicine, 11 (12) 1314, 1314. doi: 10.3390/jpm11121314

Comparison of organoids from menstrual fluid and hormone-treated endometrium: novel tools for gynecological research

2021

Journal Article

Educational attainment of same-sex and opposite-sex dizygotic twins: an individual-level pooled study of 19 twin cohorts

Silventoinen, Karri, Bogl, Leonie H., Jelenkovic, Aline, Vuoksimaa, Eero, Latvala, Antti, Li, Weilong, Tan, Qihua, Zhang, Dongfeng, Pang, Zengchang, Ordoñana, Juan R., Sánchez-Romera, Juan F., Colodro-Conde, Lucia, Willemsen, Gonneke, Bartels, Meike, van Beijsterveldt, Catharina E.M., Rebato, Esther, Corley, Robin P., Huibregtse, Brooke M., Hopper, John L., Tyler, Jessica, Duncan, Glen E., Buchwald, Dedra, Silberg, Judy L., Maes, Hermine H., Kandler, Christian, Cozen, Wendy, Hwang, Amie E., Mack, Thomas M., Nelson, Tracy L. ... Kaprio, Jaakko (2021). Educational attainment of same-sex and opposite-sex dizygotic twins: an individual-level pooled study of 19 twin cohorts. Hormones and Behavior, 136 105054, 1-6. doi: 10.1016/j.yhbeh.2021.105054

Educational attainment of same-sex and opposite-sex dizygotic twins: an individual-level pooled study of 19 twin cohorts

2021

Journal Article

Identical twins carry a persistent epigenetic signature of early genome programming

van Dongen, Jenny, Gordon, Scott D., McRae, Allan F., Odintsova, Veronika V., Mbarek, Hamdi, Breeze, Charles E., Sugden, Karen, Lundgren, Sara, Castillo-Fernandez, Juan E., Hannon, Eilis, Moffitt, Terrie E., Hagenbeek, Fiona A., van Beijsterveldt, Catharina E. M., Jan Hottenga, Jouke, Tsai, Pei-Chien, van Dongen, Jenny, Hottenga, Jouke-Jan, McRae, Allan F., Sugden, Karen, Castillo-Fernandez, Juan E., Hannon, Eilis, Moffitt, Terrie E., Hottenga, Jouke-Jan, de Geus, Eco J. C., Spector, Timothy D., Min, Josine L., Hemani, Gibran, Ehli, Erik A., Paul, Franziska ... Genetics of DNA Methylation Consortium (2021). Identical twins carry a persistent epigenetic signature of early genome programming. Nature Communications, 12 (1) 5618, 5618. doi: 10.1038/s41467-021-25583-7

Identical twins carry a persistent epigenetic signature of early genome programming

2021

Journal Article

Genetic analysis of endometriosis and depression identifies shared loci and implicates causal links with gastric mucosa abnormality

Adewuyi, Emmanuel O., Mehta, Divya, Sapkota, Yadav, Auta, Asa, Yoshihara, Kosuke, Nyegaard, Mette, Griffiths, Lyn R., Montgomery, Grant W., Chasman, Daniel I. and Nyholt, Dale R. (2021). Genetic analysis of endometriosis and depression identifies shared loci and implicates causal links with gastric mucosa abnormality. Human Genetics, 140 (3), 529-552. doi: 10.1007/s00439-020-02223-6

Genetic analysis of endometriosis and depression identifies shared loci and implicates causal links with gastric mucosa abnormality

2021

Journal Article

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

Võsa, Urmo, Claringbould, Annique, Westra, Harm-Jan, Bonder, Marc Jan, Deelen, Patrick, Zeng, Biao, Kirsten, Holger, Saha, Ashis, Kreuzhuber, Roman, Yazar, Seyhan, Brugge, Harm, Oelen, Roy, de Vries, Dylan H., van der Wijst, Monique G. P., Kasela, Silva, Pervjakova, Natalia, Alves, Isabel, Favé, Marie-Julie, Agbessi, Mawussé, Christiansen, Mark W., Jansen, Rick, Seppälä, Ilkka, Tong, Lin, Teumer, Alexander, Schramm, Katharina, Hemani, Gibran, Verlouw, Joost, Yaghootkar, Hanieh, Sönmez Flitman, Reyhan ... i2QTL Consortium (2021). Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. Nature Genetics, 53 (9), 1300-1310. doi: 10.1038/s41588-021-00913-z

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

2021

Journal Article

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

Min, Josine L., Hemani, Gibran, Hannon, Eilis, Dekkers, Koen F., Castillo-Fernandez, Juan, Luijk, René, Carnero-Montoro, Elena, Lawson, Daniel J., Burrows, Kimberley, Suderman, Matthew, Bretherick, Andrew D., Richardson, Tom G., Klughammer, Johanna, Iotchkova, Valentina, Sharp, Gemma, Al Khleifat, Ahmad, Shatunov, Aleksey, Iacoangeli, Alfredo, McArdle, Wendy L., Ho, Karen M., Kumar, Ashish, Söderhäll, Cilla, Soriano-Tárraga, Carolina, Giralt-Steinhauer, Eva, Kazmi, Nabila, Mason, Dan, McRae, Allan F., Corcoran, David L., Sugden, Karen ... BIOS Consortium (2021). Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation. Nature Genetics, 53 (9), 1311-1321. doi: 10.1038/s41588-021-00923-x

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

2021

Journal Article

Genetic analyses of gynecological disease identify genetic relationships between uterine fibroids and endometrial cancer, and a novel endometrial cancer genetic risk region at the WNT4 1p36.12 locus

Kho, Pik Fang, Mortlock, Sally, Endometrial Cancer Association Consortium , International Endometriosis Genetics Consortium, Rogers, Peter A. W., Nyholt, Dale R., Montgomery, Grant W., Spurdle, Amanda B., Glubb, Dylan M. and O'Mara, Tracy A. (2021). Genetic analyses of gynecological disease identify genetic relationships between uterine fibroids and endometrial cancer, and a novel endometrial cancer genetic risk region at the WNT4 1p36.12 locus. Human Genetics, 140 (9), 1353-1365. doi: 10.1007/s00439-021-02312-0

Genetic analyses of gynecological disease identify genetic relationships between uterine fibroids and endometrial cancer, and a novel endometrial cancer genetic risk region at the WNT4 1p36.12 locus

2021

Journal Article

Neuropeptide S receptor 1 is a nonhormonal treatment target in endometriosis

Tapmeier, Thomas T., Rahmioglu, Nilufer, Lin, Jianghai, De Leo, Bianca, Obendorf, Maik, Raveendran, Muthuswamy, Fischer, Oliver M., Bafligil, Cemsel, Guo, Manman, Harris, Ronald Alan, Hess-Stumpp, Holger, Laux-Biehlmann, Alexis, Lowy, Ernesto, Lunter, Gerton, Malzahn, Jessica, Martin, Nicholas G., Martinez, Fernando O., Manek, Sanjiv, Mesch, Stefanie, Montgomery, Grant W., Morris, Andrew P., Nagel, Jens, Simmons, Heather A., Brocklebank, Denise, Shang, Catherine, Treloar, Susan, Wells, Graham, Becker, Christian M., Oppermann, Udo ... Zondervan, Krina T. (2021). Neuropeptide S receptor 1 is a nonhormonal treatment target in endometriosis. Science Translational Medicine, 13 (608) eabd6469, 1-12. doi: 10.1126/scitranslmed.abd6469

Neuropeptide S receptor 1 is a nonhormonal treatment target in endometriosis

2021

Journal Article

Phantom epistasis between unlinked loci

Hemani, Gibran, Powell, Joseph E., Wang, Huanwei, Shakhbazov, Konstantin, Westra, Harm-Jan, Esko, Tonu, Henders, Anjali K., McRae, Allan F., Martin, Nicholas G., Metspalu, Andres, Franke, Lude, Montgomery, Grant W., Goddard, Michael E., Gibson, Greg, Yang, Jian and Visscher, Peter M. (2021). Phantom epistasis between unlinked loci. Nature, 596 (7871), E1-E3. doi: 10.1038/s41586-021-03765-z

Phantom epistasis between unlinked loci

2021

Journal Article

Protocol for a case-control study investigating the clinical phenotypes and genetic regulation of endometriosis in Indian women: The ECGRI study

Gajbhiye, Rahul K., Montgomery, Grant, Pai, Murlidhar V, Phukan, Pranay, Shekhar, Shashank, Padte, Kedar, Dasmahapatra, Pramathes, John, Bimal M., Shembekar, Chaitanya, Bhurke, Aishwarya V., Bagde, Nilajkumar, Kulkarni, Ketki, Sardeshpande, Nagendra, Humane, Anil, Mahobia, Swati, Shah, Millind, Singh, Uma, Srivastava, Aarti, Mishra, Gita, Warty, Neeta, Chandra, Sunita and Mahale, Smita D. (2021). Protocol for a case-control study investigating the clinical phenotypes and genetic regulation of endometriosis in Indian women: The ECGRI study. BMJ Open, 11 (8) e050844, e050844. doi: 10.1136/bmjopen-2021-050844

Protocol for a case-control study investigating the clinical phenotypes and genetic regulation of endometriosis in Indian women: The ECGRI study

2021

Journal Article

Genetic insights into biological mechanisms governing human ovarian ageing

Ruth, Katherine S., Day, Felix R., Hussain, Jazib, Martínez-Marchal, Ana, Aiken, Catherine E., Azad, Ajuna, Thompson, Deborah J., Knoblochova, Lucie, Abe, Hironori, Tarry-Adkins, Jane L., Gonzalez, Javier Martin, Fontanillas, Pierre, Claringbould, Annique, Bakker, Olivier B., Sulem, Patrick, Walters, Robin G., Terao, Chikashi, Turon, Sandra, Horikoshi, Momoko, Lin, Kuang, Onland-Moret, N. Charlotte, Sankar, Aditya, Hertz, Emil Peter Thrane, Timshel, Pascal N., Shukla, Vallari, Borup, Rehannah, Olsen, Kristina W., Aguilera, Paula, Ferrer-Roda, Mònica ... Perry, John R. B. (2021). Genetic insights into biological mechanisms governing human ovarian ageing. Nature, 596 (7872), 393-397. doi: 10.1038/s41586-021-03779-7

Genetic insights into biological mechanisms governing human ovarian ageing

2021

Journal Article

Genetic Relationship Between Endometriosis and Melanoma

Yang, Fei, Mortlock, Sally, MacGregor, Stuart, Iles, Mark M., Landi, Maria Teresa, Shi, Jianxin, Law, Matthew H., Montgomery, Grant W. and on behalf of The International Endometriosis Genetics Consortium (2021). Genetic Relationship Between Endometriosis and Melanoma. Frontiers in Reproductive Health, 3 711123, 1-10. doi: 10.3389/frph.2021.711123

Genetic Relationship Between Endometriosis and Melanoma

2021

Journal Article

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Mullins, Niamh, Forstner, Andreas J., O'Connell, Kevin S., Coombes, Brandon, Coleman, Jonathan R I, Qiao, Zhen, Als, Thomas D., Bigdeli, Tim B., Børte, Sigrid, Bryois, Julien, Charney, Alexander W., Drange, Ole Kristian, Gandal, Michael J., Hagenaars, Saskia P., Ikeda, Masashi, Kamitaki, Nolan, Kim, Minsoo, Krebs, Kristi, Panagiotaropoulou, Georgia, Schilder, Brian M., Sloofman, Laura G., Steinberg, Stacy, Trubetskoy, Vassily, Winsvold, Bendik S., Won, Hong-Hee, Abramova, Liliya, Adorjan, Kristina, Agerbo, Esben, Al Eissa, Mariam ... Andreassen, Ole A. (2021). Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature genetics, 53 (6), 817-829. doi: 10.1038/s41588-021-00857-4

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

2021

Journal Article

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

Nabais, Marta F., Laws, Simon M., Lin, Tian, Vallerga, Costanza L., Armstrong, Nicola J., Blair, Ian P., Kwok, John B., Mather, Karen A., Mellick, George D., Sachdev, Perminder S., Wallace, Leanne, Henders, Anjali K., Zwamborn, Ramona A. J., Hop, Paul J., Lunnon, Katie, Pishva, Ehsan, Roubroeks, Janou A. Y., Soininen, Hilkka, Tsolaki, Magda, Mecocci, Patrizia, Lovestone, Simon, Kloszewska, Iwona, Vellas, Bruno, Furlong, Sarah, Garton, Fleur C., Henderson, Robert D., Mathers, Susan, McCombe, Pamela A., Needham, Merrilee ... McRae, Allan F. (2021). Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. Genome Biology, 22 (1) 90, 1-30. doi: 10.1186/s13059-021-02275-5

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

2021

Journal Article

Genetic regulation of physiological reproductive lifespan and female fertility

McGrath, Isabelle M., Mortlock, Sally and Montgomery, Grant W. (2021). Genetic regulation of physiological reproductive lifespan and female fertility. International Journal of Molecular Sciences, 22 (5) 2556, 1-13. doi: 10.3390/ijms22052556

Genetic regulation of physiological reproductive lifespan and female fertility

2021

Journal Article

Prevalence and incidence of endometriosis in Australian women: a data linkage cohort study

Rowlands, I. J., Abbott, J. A., Montgomery, G. W., Hockey, R., Rogers, P. and Mishra, G. D. (2021). Prevalence and incidence of endometriosis in Australian women: a data linkage cohort study. BJOG, 128 (4) 1471-0528.16447, 657-665. doi: 10.1111/1471-0528.16447

Prevalence and incidence of endometriosis in Australian women: a data linkage cohort study

2021

Journal Article

Elucidating the role of long intergenic non-coding RNA 339 in human endometrium and endometriosis

Holdsworth-Carson, Sarah J., Churchill, Molly, Donoghue, Jacqueline F., Mortlock, Sally, Fung, Jenny N., Sloggett, Clare, Chung, Jessica, Cann, Leonie, Teh, Wan Tinn, Campbell, Katie-Rose, Luwor, Rodney, Healey, Martin, Montgomery, Grant, Girling, Jane E. and Rogers, Peter A. W. (2021). Elucidating the role of long intergenic non-coding RNA 339 in human endometrium and endometriosis. Molecular Human Reproduction, 27 (3) gaab010. doi: 10.1093/molehr/gaab010

Elucidating the role of long intergenic non-coding RNA 339 in human endometrium and endometriosis

2021

Journal Article

Comparison of Familial, Polygenic and Biochemical Predictors of Mortality

Whitfield, John B., Colodro-Conde, Lucía, Timmers, Paul R. H. J., Joshi, Peter K., Montgomery, Grant W. and Martin, Nicholas G. (2021). Comparison of Familial, Polygenic and Biochemical Predictors of Mortality. Twin Research and Human Genetics, 23 (6), 307-315. doi: 10.1017/thg.2020.89

Comparison of Familial, Polygenic and Biochemical Predictors of Mortality

Funding

Current funding

  • 2020 - 2024
    Improved clinical outcomes from understanding risk factors for reproductive diseases
    NHMRC Investigator Grants
    Open grant

Past funding

  • 2022 - 2023
    Environmental Risk Factors for Endometriosis
    Endometriosis Australia Ltd
    Open grant
  • 2019 - 2023
    Endometriosis Susceptibility Genes in Endometrial Stem/Progenitor Cells
    United States Congressionally Directed Medical Research Programs - Peer Reviewed Medical Research Program
    Open grant
  • 2019 - 2023
    Causes of Endometriosis
    Research Donation Generic
    Open grant
  • 2018 - 2020
    A detailed analysis of existing databases from the Australian Longitudinal Study on Women's Health (MRFF Accelerated Research Program administered by Jean Hailes Foundation)
    MRFF Accelerated Research Program administered by Jean Hailes Foundation
    Open grant
  • 2018 - 2021
    Differential regulation of endometrial gene expression in endometriosis and disease subtypes
    NHMRC Project Grant
    Open grant
  • 2017 - 2024
    ACRF Cancer Ultrastructure and Function Facility
    Australian Cancer Research Foundation
    Open grant
  • 2017 - 2021
    M-PreM study: Reproductive factors, from menarche to pre-menopause, and the risk of cardiometabolic and respiratory conditions before menopause
    NHMRC Project Grant
    Open grant
  • 2016 - 2017
    Genome-wide analysis of gene coding variants increasing risk of endometriosis
    NHMRC Project Grant
    Open grant
  • 2016 - 2019
    Identification and function of genes that increase risk for endometriosis (NHMRC Project Grant administered by The University of Melbourne).
    University of Melbourne
    Open grant
  • 2016 - 2019
    Translating gene discovery for key diseases into clinical outcomes
    NHMRC Research Fellowship
    Open grant
  • 2009 - 2011
    The immunogenetics of ankylosing spondylitis: a genetic and functional investigation of IL23R and related genes
    NHMRC Project Grant
    Open grant

Supervision

Availability

Professor Grant Montgomery is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Investigating the relationship between Endometriosis and Cancer risk.

    Associate Advisor

    Other advisors: Dr Sally Mortlock

  • Doctor Philosophy

    Exploring the role of clinical, lifestyle, environmental and molecular factors in endometriosis risk

    Associate Advisor

    Other advisors: Dr Allan McRae, Dr Sally Mortlock

  • Doctor Philosophy

    Regulation of the endocannabinoid system in the endometrium across menstrual cycle and implications in endometriosis

    Associate Advisor

    Other advisors: Dr Brett McKinnon, Dr Akwasi Amoako

  • Master Philosophy

    Spatial resolved analysis of endometrial tissue

    Associate Advisor

    Other advisors: Dr Brett McKinnon

Completed supervision

Media

Enquiries

Contact Professor Grant Montgomery directly for media enquiries about:

  • Endometriosis
  • Genetics

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