Dr Rakesh Naduvile Veedu
Dr

Rakesh Naduvile Veedu

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Availability

Dr Rakesh Naduvile Veedu is:
Available for supervision
Media expert

Fields of research

Medicinal and biomolecular chemistry Organic chemistry

Qualifications

  • Bachelor of Science, Mangalore University
  • Masters (Coursework) of Science, Griffith University
  • Doctor of Philosophy, The University of Queensland

Research interests

  • Novel Nucleic Acid-based Nanodevices for tackling Solid Tumours and Alzheimer's Disease

    Nucleic Acid Aptamers, Antisense therapy, siRNA, MRI and PET imaging

Search Professor Rakesh Naduvile Veedu’s works on UQ eSpace

54 works between 2004 and 2018
All (54) Journal Article (47) Book Chapter (2) Conference Publication (3) Other Outputs (2)

1 - 20 of 54 works

2018

Journal Article

Development of DNA aptamers targeting low-molecular-weight amyloid-β peptide aggregates in vitro

Chakravarthy, Madhuri, AlShamaileh, Hadi, Huang, He, Tannenberg, Rudi K., Chen, Suxiang, Worrall, Simon, Dodd, Peter R. and Veedu, Rakesh N. (2018). Development of DNA aptamers targeting low-molecular-weight amyloid-β peptide aggregates in vitro. Chemical Communications, 54 (36), 4593-4596. doi: 10.1039/c8cc02256a

Development of DNA aptamers targeting low-molecular-weight amyloid-β peptide aggregates in vitro

2018

Journal Article

Self-assembling asymmetric peptide-dendrimer micelles - a platform for effective and versatile in vitro nucleic acid delivery

Kokil, Ganesh R., Veedu, Rakesh N., Le, Bao Tri, Ramm, Grant A. and Parekh, Harendra S. (2018). Self-assembling asymmetric peptide-dendrimer micelles - a platform for effective and versatile in vitro nucleic acid delivery. Scientific Reports, 8 (1) 4832, 4832. doi: 10.1038/s41598-018-22902-9

Self-assembling asymmetric peptide-dendrimer micelles - a platform for effective and versatile in vitro nucleic acid delivery

2017

Journal Article

Next generation nucleic acid aptamers with two base modified nucleotides improve the binding affinity and potency

Naduvile Veedu, Rakesh and Al Shamaileh, Hadi (2017). Next generation nucleic acid aptamers with two base modified nucleotides improve the binding affinity and potency. ChemBioChem, 18 (16), 1565-1567. doi: 10.1002/cbic.201700276

Next generation nucleic acid aptamers with two base modified nucleotides improve the binding affinity and potency

2017

Journal Article

Development of an efficient G-quadruplex stabilized thrombin binding aptamer containing 3-carbon spacer molecule

Aaldering, Lukas J. , Poongavanam, Vasanthanathan , Murugan, N. Arul , Jørgensen, Per Trolle , Wengel, Jesper and Veedu, Rakesh N. (2017). Development of an efficient G-quadruplex stabilized thrombin binding aptamer containing 3-carbon spacer molecule. ChemBioChem, 18 (8), 755-763. doi: 10.1002/cbic.201600654

Development of an efficient G-quadruplex stabilized thrombin binding aptamer containing 3-carbon spacer molecule

2017

Journal Article

Nucleic acid-based theranostics for tackling Alzheimer's disease

Chakravarthy, Madhuri, Chen, Suxiang, Dodd, Peter R. and Veedu, Rakesh N. (2017). Nucleic acid-based theranostics for tackling Alzheimer's disease. Theranostics, 7 (16) 21529, 3933-3947. doi: 10.7150/thno.21529

Nucleic acid-based theranostics for tackling Alzheimer's disease

2015

Journal Article

Targeting VEGF with LNA-stabilized G-rich oligonucleotide for efficient breast cancer inhibition

Edwards, Stacey L., Poongavanam, Vasanthanathan, Kanwar, Jagat R., Roy, Kislay, Hillman, Kristine M., Prasad, Neerati, Leth-Larsen, Rikke, Petersen, Michael, Marusic, Maja, Plavec, Janez, Wengel, Jesper and Veedu, Rakesh N. (2015). Targeting VEGF with LNA-stabilized G-rich oligonucleotide for efficient breast cancer inhibition. Chemical Communications, 51 (46), 9499-9502. doi: 10.1039/c5cc02756j

Targeting VEGF with LNA-stabilized G-rich oligonucleotide for efficient breast cancer inhibition

2015

Journal Article

Comments on photochromism of 3-(3-pyridyl)sydnone and 4-alkenylsydnones

Wentrup, Curt, Kvaskoff, David and Veedu, Rakesh N (2015). Comments on photochromism of 3-(3-pyridyl)sydnone and 4-alkenylsydnones. Journal of Photochemistry and Photobiology A: Chemistry, 298, 62-63. doi: 10.1016/j.jphotochem.2014.10.010

Comments on photochromism of 3-(3-pyridyl)sydnone and 4-alkenylsydnones

2015

Journal Article

Smart functional nucleic acid chimeras: enabling tissue specific RNA targeting therapy

Aaldering, Lukas J., Tayeb, Hossam, Krishnan, Shilpa, Fletcher, Susan, Wilton, Stephen D. and Veedu, Rakesh N. (2015). Smart functional nucleic acid chimeras: enabling tissue specific RNA targeting therapy. RNA Biology, 12 (4), 412-425. doi: 10.1080/15476286.2015.1017234

Smart functional nucleic acid chimeras: enabling tissue specific RNA targeting therapy

2015

Journal Article

Type 2 diabetes mellitus: limitations of conventional therapies and intervention with nucleic acid-based therapeutics

Kokil, Ganesh R., Veedu, Rakesh N., Ramm, Grant A., Prins, Johannes B. and Parekh, Harendra S. (2015). Type 2 diabetes mellitus: limitations of conventional therapies and intervention with nucleic acid-based therapeutics. Chemical Reviews, 115 (11), 4719-4743. doi: 10.1021/cr5002832

Type 2 diabetes mellitus: limitations of conventional therapies and intervention with nucleic acid-based therapeutics

2014

Journal Article

Computational investigation of Locked Nucleic Acid (LNA) nucleotides in the active sites of DNA polymerases by molecular docking simulations

Poongavanam, Vasanthanathan, Madala, Praveen K., Højland, Torben and Veedu, Rakesh N. (2014). Computational investigation of Locked Nucleic Acid (LNA) nucleotides in the active sites of DNA polymerases by molecular docking simulations. PLoS One, 9 (7) e102126, 1-7. doi: 10.1371/journal.pone.0102126

Computational investigation of Locked Nucleic Acid (LNA) nucleotides in the active sites of DNA polymerases by molecular docking simulations

2014

Journal Article

Quencher-free molecular beacons as probes for oligonucleotides containing CAG repeat sequences

Kim K.T., Veedu R.N., Seo Y.J. and Kim B.H. (2014). Quencher-free molecular beacons as probes for oligonucleotides containing CAG repeat sequences. Chemical Communications, 50 (13), 1561-1563. doi: 10.1039/c3cc48853e

Quencher-free molecular beacons as probes for oligonucleotides containing CAG repeat sequences

2014

Conference Publication

Sydnone photochemistry: Direct observation of earl's bicyclic lactone valence isomers (oxadiazabicyclo[2.1.0] pentanones), formation of carbodiimides, reaction mechanism, and photochromism

Veedu, Rakesh N., Kvaskoff, David and Wentrup, Curt (2014). Sydnone photochemistry: Direct observation of earl's bicyclic lactone valence isomers (oxadiazabicyclo[2.1.0] pentanones), formation of carbodiimides, reaction mechanism, and photochromism. 6th Heron Island Conference on Reactive Intermediates and Unusual Molecules, Heron Island, Qld, Australia, 7 - 13 July 2013. Collingwood, VIC Australia: CSIRO. doi: 10.1071/CH13536

Sydnone photochemistry: Direct observation of earl's bicyclic lactone valence isomers (oxadiazabicyclo[2.1.0] pentanones), formation of carbodiimides, reaction mechanism, and photochromism

2013

Journal Article

Multifunctional and multitargeted nanoparticles for drug delivery to overcome barriers of drug resistance in human cancers

Dawar, Swati, Singh, Neha, Kanwar, Rupinder K., Kennedy, Richard Lee, Veedu, Rakesh N., Zhou, Shu-Feng, Krishnakumar, Subramanian, Hazra, Sarbani, Sasidharan, Sreenivasan, Duan, Wei and Kanwar, Jagat R. (2013). Multifunctional and multitargeted nanoparticles for drug delivery to overcome barriers of drug resistance in human cancers. Drug Discovery Today, In Press, Corrected Proof (23-24), 1-9. doi: 10.1016/j.drudis.2013.09.009

Multifunctional and multitargeted nanoparticles for drug delivery to overcome barriers of drug resistance in human cancers

2013

Journal Article

G-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex fold

Marušič, Maja, Veedu, Rakesh N., Wengel, Jesper and Plavec, Janez (2013). G-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex fold. Nucleic Acids Research, Advance Access (20), 1-13. doi: 10.1093/nar/gkt697

G-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex fold

2013

Journal Article

Nucleic acid aptamers as novel class of therapeutics to mitigate Alzheimer's disease pathology

Tannenberg, Rudi K., Al Shamaileh, Hadi, Lauridsen, Lasse H., Kanwar, Jagat R., Dodd, Peter R. and Veedu, Rakesh N. (2013). Nucleic acid aptamers as novel class of therapeutics to mitigate Alzheimer's disease pathology. Current Alzheimer Research, 10 (4), 442-448. doi: 10.2174/1567205011310040009

Nucleic acid aptamers as novel class of therapeutics to mitigate Alzheimer's disease pathology

2013

Journal Article

Synthesis of DNA Oligonucleotides containing C5-Ethynylbenzenesulfonamide-modified nucleotides (EBNA) by polymerases towards the construction of base functionalized nucleic acids

Goubet, Astrid, Chardon, Antoine, Kumar, Pawan, Sharma, Pawan K. and Veedu, Rakesh N. (2013). Synthesis of DNA Oligonucleotides containing C5-Ethynylbenzenesulfonamide-modified nucleotides (EBNA) by polymerases towards the construction of base functionalized nucleic acids. Bioorganic & Medicinal Chemistry Letters, 23 (3), 761-763. doi: 10.1016/j.bmcl.2012.11.096

Synthesis of DNA Oligonucleotides containing C5-Ethynylbenzenesulfonamide-modified nucleotides (EBNA) by polymerases towards the construction of base functionalized nucleic acids

2013

Journal Article

Aptamer-targeted hyperbranched polymers: towards greater specificity for tumours in vivo

Coles, Daniel J., Rolfe, Barbara E., Boase, Nathan R. B., Veedu, Rakesh N. and Thurecht, Kristofer J. (2013). Aptamer-targeted hyperbranched polymers: towards greater specificity for tumours in vivo. Chemical Communications, 49 (37), 3836-3838. doi: 10.1039/c3cc00127j

Aptamer-targeted hyperbranched polymers: towards greater specificity for tumours in vivo

2013

Journal Article

Targeted multimodal liposomes for nano-delivery and imaging: An avenger for drug resistance and cancer

Gurudevan, Sneha, Kanwar, Rupinder K., Veedu, Rakesh N., Sasidharan, Sreenivasan, Kennedy, Richard L., Walder, Ken, Prasad, Neerati and Kanwar, Jagat R. (2013). Targeted multimodal liposomes for nano-delivery and imaging: An avenger for drug resistance and cancer. Current Gene Therapy, 13 (5), 322-334. doi: 10.2174/156652321305131212123558

Targeted multimodal liposomes for nano-delivery and imaging: An avenger for drug resistance and cancer

2013

Journal Article

Selenomethylene locked nucleic acid enables reversible hybridization in response to redox changes

Morihiro, Kunihiko, Kodama, Tetsuya, Kentefu, Moai, Yoshihiro, Veedu, Rakesh N. and Obika, Satoshi (2013). Selenomethylene locked nucleic acid enables reversible hybridization in response to redox changes. Angewandte Chemie-International Edition, 52 (19), 5074-5078. doi: 10.1002/anie.201300555

Selenomethylene locked nucleic acid enables reversible hybridization in response to redox changes

2012

Journal Article

Synthesis of selenomethylene-locked nucleic acid (SeLNA)-modified oligonucleotides by polymerases

Wheeler, Megan, Chardon, Antoine, Goubet, Astrid, Morihiro, Kunihiko, Tsan, Sze Yee, Edwards, Stacey L., Kodama, Tetsuya, Obika, Satoshi and Veedu, Rakesh N. (2012). Synthesis of selenomethylene-locked nucleic acid (SeLNA)-modified oligonucleotides by polymerases. Chemical Communications, 48 (89), 11020-11022. doi: 10.1039/C2CC36464F

Synthesis of selenomethylene-locked nucleic acid (SeLNA)-modified oligonucleotides by polymerases

Past funding

  • 2014 - 2016
    The ghrelin axis in prostate cancer (NHMRC Project Grant administered by QUT)
    Queensland University of Technology
    Open grant
  • 2011
    Nano-Doctors against snake venom toxins
    UQ Early Career Researcher
    Open grant
  • 2010 - 2013
    Modified Nucleotide Aptamers as Therapeutics for Alzheimer's Disease
    UQ Postdoctoral Research Fellowship
    Open grant

Availability

Dr Rakesh Naduvile Veedu is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

Contact Dr Rakesh Naduvile Veedu directly for media enquiries about:

  • Acid - nucleic
  • Chemical biology
  • Nucleic acids

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