Australian Institute for Bioengineering and Nanotechnology
Availability:
Available for supervision
Scaling-up fermentation processes is not straightforward due to the emergence of concentration gradients at scale. For gas fermentation processes, with CO2, CO and CH4 and H2, scaling is even more challenging as high mass transfer rates need to be obtained. In his work, Lars is developing a framework to reliably scale-up gas fermentation processes, considering both mass transfer and concentration gradients. We aim to employ mechanistic models, combined with wet-lab data, to develop relationships and fluid dynamic (CFD) models to estimate the fermentation performance at industrial scale. He specialised in topics like bioreactor and bioprocess design, bioprocess scale-up/scale-down, mass transfer and transport phenomena, metabolic and kinetic modelling and simulation techniques.
