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Dr Xaria Li
Dr

Xaria Li

Email: 

Overview

Availability

Dr Xaria Li is:
Available for supervision

Qualifications

  • Bachelor (Honours) of Biomedical Sciences, The University of Queensland
  • Doctor of Philosophy of Biomedical Sciences, The University of Queensland

Works

Search Professor Xaria Li’s works on UQ eSpace

27 works between 2017 and 2024

1 - 20 of 27 works

2024

Journal Article

Cell-intrinsic C5a synergizes with Dectin-1 in macrophages to mediate fungal killing

Li, Xaria X., Fung, Jenny N., Clark, Richard J., Lee, John D. and Woodruff, Trent M. (2024). Cell-intrinsic C5a synergizes with Dectin-1 in macrophages to mediate fungal killing. Proceedings of the National Academy of Sciences, 121 (5) e2314627121, 1-10. doi: 10.1073/pnas.2314627121

Cell-intrinsic C5a synergizes with Dectin-1 in macrophages to mediate fungal killing

2023

Journal Article

Protocol for cell-based screening assay to measure ERK1/2 phosphorylation as a readout for complement receptor activation

Li, Xaria X. and Woodruff, Trent M. (2023). Protocol for cell-based screening assay to measure ERK1/2 phosphorylation as a readout for complement receptor activation. STAR Protocols, 4 (4) 102758, 1-20. doi: 10.1016/j.xpro.2023.102758

Protocol for cell-based screening assay to measure ERK1/2 phosphorylation as a readout for complement receptor activation

2023

Journal Article

Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors

Yadav, Manish K., Maharana, Jagannath, Yadav, Ravi, Saha, Shirsha, Sarma, Parishmita, Soni, Chahat, Singh, Vinay, Saha, Sayantan, Ganguly, Manisankar, Li, Xaria X., Mohapatra, Samanwita, Mishra, Sudha, Khant, Htet A., Chami, Mohamed, Woodruff, Trent M., Banerjee, Ramanuj, Shukla, Arun K. and Gati, Cornelius (2023). Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186 (22), 4956-4973.e21. doi: 10.1016/j.cell.2023.09.020

Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors

2023

Journal Article

The concise guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

Alexander, Stephen P. H., Christopoulos, Arthur, Davenport, Anthony P., Kelly, Eamonn, Mathie, Alistair A., Peters, John A., Veale, Emma L., Armstrong, Jane F., Faccenda, Elena, Harding, Simon D., Davies, Jamie A., Abbracchio, Maria Pia, Abraham, George, Agoulnik, Alexander, Alexander, Wayne, Al‐hosaini, Khaled, Bäck, Magnus, Baker, Jillian G., Barnes, Nicholas M., Bathgate, Ross, Beaulieu, Jean‐Martin, Beck‐Sickinger, Annette G., Behrens, Maik, Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel J. M., Blaho, Victoria, Boulay, Francois, Bousquet, Corinne ... Ye, Richard D. (2023). The concise guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. British Journal of Pharmacology, 180 (S2), S23-S144. doi: 10.1111/bph.16177

The concise guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

2023

Journal Article

Complement peptide receptors in GtoPdb v.2023.1

Cianciulli, Antonia, Coulthard, Liam, Hawksworth, Owen, Lee, John D., Li, Xaria X., Mitolo, Vincenzo, Monk, Peter, Panaro, Maria A. and Woodruff, Trent M. (2023). Complement peptide receptors in GtoPdb v.2023.1. IUPHAR/BPS Guide to Pharmacology CITE, 2023 (1). doi: 10.2218/gtopdb/f5/2023.1

Complement peptide receptors in GtoPdb v.2023.1

2023

Journal Article

TLQP-21 is a low potency partial C3aR activator on human primary macrophages

Li, Xaria X., Lee, John D., Lee, Han S., Clark, Richard J. and Woodruff, Trent M. (2023). TLQP-21 is a low potency partial C3aR activator on human primary macrophages. Frontiers in Immunology, 14 1086673, 1-10. doi: 10.3389/fimmu.2023.1086673

TLQP-21 is a low potency partial C3aR activator on human primary macrophages

2023

Journal Article

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

Albornoz, Eduardo A., Amarilla, Alberto A., Modhiran, Naphak, Parker, Sandra, Li, Xaria X., Wijesundara, Danushka K., Aguado, Julio, Zamora, Adriana Pliego, McMillan, Christopher L. D., Liang, Benjamin, Peng, Nias Y. G., Sng, Julian D. J., Saima, Fatema Tuj, Fung, Jenny N., Lee, John D., Paramitha, Devina, Parry, Rhys, Avumegah, Michael S., Isaacs, Ariel, Lo, Martin W., Miranda-Chacon, Zaray, Bradshaw, Daniella, Salinas-Rebolledo, Constanza, Rajapakse, Niwanthi W., Wolvetang, Ernst J., Munro, Trent P., Rojas-Fernandez, Alejandro, Young, Paul R., Stacey, Katryn J. ... Woodruff, Trent M. (2023). SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein. Molecular Psychiatry, 28 (7), 2878-2893. doi: 10.1038/s41380-022-01831-0

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

2022

Journal Article

Success in navigating hurdles to oral delivery of a bioactive peptide complement antagonist through use of nanoparticles to increase bioavailability and in vivo efficacy

Xu, Weizhi, Kumar, Vinod, Cui, Cedric S., Li, Xaria X., Whittaker, Andrew K., Xu, Zhi Ping, Smith, Maree T., Woodruff, Trent M. and Han, Felicity Y (2022). Success in navigating hurdles to oral delivery of a bioactive peptide complement antagonist through use of nanoparticles to increase bioavailability and in vivo efficacy. Advanced Therapeutics, 5 (12) 2200109, 2200109. doi: 10.1002/adtp.202200109

Success in navigating hurdles to oral delivery of a bioactive peptide complement antagonist through use of nanoparticles to increase bioavailability and in vivo efficacy

2021

Journal Article

Unexpected off-target activities for recombinant C5a in human macrophages

Li, Xaria X., Gorman, Declan M., Lee, John D., Clark, Richard J. and Woodruff, Trent M. (2021). Unexpected off-target activities for recombinant C5a in human macrophages. Journal of Immunology, 208 (1), 133-142. doi: 10.4049/jimmunol.2100444

Unexpected off-target activities for recombinant C5a in human macrophages

2021

Journal Article

Development of synthetic human and mouse C5a: application to binding and functional assays in vitro and in vivo

Gorman, Declan M., Li, Xaria X., Payne, Colton D., Cui, Cedric S., Lee, John D., Rosengren, K. Johan, Woodruff, Trent M. and Clark, Richard J. (2021). Development of synthetic human and mouse C5a: application to binding and functional assays in vitro and in vivo. ACS Pharmacology and Translational Science, 4 (6) acsptsci.1c00199, 1808-1817. doi: 10.1021/acsptsci.1c00199

Development of synthetic human and mouse C5a: application to binding and functional assays in vitro and in vivo

2021

Journal Article

Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity

Gorman, Declan M., Li, Xaria X., Lee, John D., Fung, Jenny N., Cui, Cedric S., Lee, Han Siean, Rolfe, Barbara E., Woodruff, Trent M. and Clark, Richard J. (2021). Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity. Journal of Medicinal Chemistry, 64 (22) acs.jmedchem.1c01174, 16598-16608. doi: 10.1021/acs.jmedchem.1c01174

Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity

2021

Journal Article

Anaphylatoxin receptor promiscuity for commonly used complement C5a peptide agonists

Li, Xaria X., Clark, Richard J. and Woodruff, Trent M. (2021). Anaphylatoxin receptor promiscuity for commonly used complement C5a peptide agonists. International Immunopharmacology, 100 108074, 108074. doi: 10.1016/j.intimp.2021.108074

Anaphylatoxin receptor promiscuity for commonly used complement C5a peptide agonists

2021

Journal Article

Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors

Pandey, Shubhi, Kumari, Punita, Baidya, Mithu, Kise, Ryoji, Cao, Yubo, Dwivedi-Agnihotri, Hemlata, Banerjee, Ramanuj, Li, Xaria X., Cui, Cedric S., Lee, John D., Kawakami, Kouki, Maharana, Jagannath, Ranjan, Ashutosh, Chaturvedi, Madhu, Jhingan, Gagan Deep, Laporte, Stéphane A., Woodruff, Trent M., Inoue, Asuka and Shukla, Arun K. (2021). Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors. Molecular Cell, 81 (22), 4605-4621.e11. doi: 10.1016/j.molcel.2021.09.007

Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors

2021

Other Outputs

Investigating the immunopharmacology of the complement C5a receptors, C5aR1 and C5aR2

Li, Xiang (2021). Investigating the immunopharmacology of the complement C5a receptors, C5aR1 and C5aR2. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/339adea

Investigating the immunopharmacology of the complement C5a receptors, C5aR1 and C5aR2

2021

Journal Article

Optimisation of a microfluidic method for the delivery of a small peptide

Han, Felicity Y., Xu, Weizhi, Kumar, Vinod, Cui, Cedric S., Li, Xaria, Jiang, Xingyu, Woodruff, Trent M., Whittaker, Andrew K. and Smith, Maree T. (2021). Optimisation of a microfluidic method for the delivery of a small peptide. Pharmaceutics, 13 (9) 1505, 1505. doi: 10.3390/pharmaceutics13091505

Optimisation of a microfluidic method for the delivery of a small peptide

2021

Journal Article

The concise guide to pharmacology 2021/22: G protein‐coupled receptors

Alexander, Stephen PH, Christopoulos, Arthur, Davenport, Anthony P, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Abbracchio, Maria Pia, Alexander, Wayne, Al‐hosaini, Khaled, Bäck, Magnus, Barnes, Nicholas M., Bathgate, Ross, Beaulieu, Jean‐Martin, Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel J.M., Blaho, Victoria, Boulay, Francois, Bousquet, Corinne, Bräuner‐Osborne, Hans, Burnstock, Geoffrey, Caló, Girolamo ... Ye, Richard D. (2021). The concise guide to pharmacology 2021/22: G protein‐coupled receptors. British Journal of Pharmacology, 178 (S1), S27-S156. doi: 10.1111/bph.15538

The concise guide to pharmacology 2021/22: G protein‐coupled receptors

2021

Journal Article

Complement peptide receptors in GtoPdb v.2021.3

Cianciulli, Antonia, Coulthard, Liam, Hawksworth, Owen, Lee, John D., Li, Xaria X., Mitolo, Vincenzo, Monk, Peter, Panaro, Maria A. and Woodruff, Trent M. (2021). Complement peptide receptors in GtoPdb v.2021.3. IUPHAR/BPS Guide to Pharmacology CITE, 2021 (3), 1-13. doi: 10.2218/gtopdb/f5/2021.3

Complement peptide receptors in GtoPdb v.2021.3

2021

Journal Article

The “C3aR Antagonist” SB290157 is a partial C5aR2 agonist

Li, Xaria X., Kumar, Vinod, Clark, Richard J., Lee, John D. and Woodruff, Trent M. (2021). The “C3aR Antagonist” SB290157 is a partial C5aR2 agonist. Frontiers in Pharmacology, 11 591398, 591398. doi: 10.3389/fphar.2020.591398

The “C3aR Antagonist” SB290157 is a partial C5aR2 agonist

2020

Journal Article

Pharmacological characterisation of small molecule C5aR1 inhibitors in human cells reveals biased activities for signalling and function

Li, Xaria X., Lee, John D., Massey, Nicholas L., Guan, Carolyn, Robertson, Avril A. B., Clark, Richard J. and Woodruff, Trent M. (2020). Pharmacological characterisation of small molecule C5aR1 inhibitors in human cells reveals biased activities for signalling and function. Biochemical Pharmacology, 180 114156, 114156. doi: 10.1016/j.bcp.2020.114156

Pharmacological characterisation of small molecule C5aR1 inhibitors in human cells reveals biased activities for signalling and function

2020

Journal Article

C5aR2 activation broadly modulates the signaling and function of primary human macrophages

Li, Xaria X., Clark, Richard J. and Woodruff, Trent M. (2020). C5aR2 activation broadly modulates the signaling and function of primary human macrophages. Journal of Immunology, 205 (4), 1-11. doi: 10.4049/jimmunol.2000407

C5aR2 activation broadly modulates the signaling and function of primary human macrophages

Supervision

Availability

Dr Xaria Li is:
Available for supervision

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Media

Enquiries

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