Dr Andrew Brooks is the Group Leader of the Cytokine Receptor Signalling Group at the University of Queensland Diamantina Institute (UQ DI) within the Translational Research Institute. Andrew completed his Honours research on Flaviviruses in 1996 at the Department of Microbiology and Immunology at James Cook University and then moved to the Department of Biochemistry to study Dengue Virus where he completed his PhD in 2002. He then moved to St Jude Children’s Research Hospital in Memphis, TN, USA where he researched the role of Epstein-Barr Virus in B-cell lymphomagenesis. He then joined the research group headed by Prof Michael Waters at the Institute for Molecular Bioscience, UQ in 2006 and subsequently began his independent research group at UQ DI in 2014. Andrew’s research interests are in cytokine receptors, cell signalling, oncogenesis, and immunology. His current research focus is on the molecular mechanisms of class I cytokine receptor activation including the growth hormone receptor (GHR), thrombopoietin receptor (TpoR/MPL), IL-7 receptor, and IL-6 receptor (IL-6R). In addition, he is investigating the regulation of inflammation by HLA-G. His research has led to publications in journals including Science, Blood, Hepatology, Oncogene, Nature Cell Biology, and PNAS. He has been the secured of over $12 million in research and commercialisation funding from sources including NHMRC, ARC, Innovation Connections, and Merck. He has a number of national and international collaborations, a scientific founder of a start-up company, and is an Editorial Board member for the Journal Cancers and Human Cell. He was previously a committee member of Australian Early-Mid Career Researchers Forum (AEMCRF) launched by the Australian Academy of Science.
Sebastian is an expert on molecular pharmacology of G protein-coupled receptors (GPCRs - the largest class of cell surface recpetors and major drug targets). His lab has a particular interest in those involved in communication between the gastrointestinal tract and brain (the so-called gut-brain axis). Current foccusses include ghrelin, melanocortin 4, dopamine D2, and cholecystokinin receptors and the lab has also worked on the calcitonin, glucagon-like peptide 1 and other receptors. His lab is interested in answering complelling biological questions relating to physiology and pathophysiology of the gut-brain axis all the way down to the level of the receptor.
Sebastian is from Adelaide and received his BSc(Hons) and PhD. from the University of Adelaide, where he worked on the Aryl Hydrocarbon receptor in the lab of Murray Whitelaw. He then did postdoctoral research on haematopoitic stem cell differentiation in Kelly McNagny’s lab at the Biomedical Research Centre at the University of British Columbia before joining Patrick Sexton to work on G protein-coupled receptors at Monash University .
Sebastian is now an ARC Future Fellow with his own research program in the School of Biomedical Sciences at the University of Queensland. He remains an adjunct member of MIPS DDB as well as CCeMMP.
Sebastian has honours and PhD positions for motivated students who have a strong desire to assume ownership of a project and work independently.
Junxian Lim is an accomplished molecular biologist at the Institute for Molecular Bioscience. With a strong background in cell biology, protein biochemistry, and pharmacology, he has established himself in the field. Collaborating with researchers at universities, institutions, as well as international industry partners like AstraZeneca and Sosei Heptares, he has contributed significantly to advancing scientific knowledge.
Throughout his doctoral studies, Junxian authored seven ground-breaking studies focused on the development of novel bioactive inhibitors targeting immune cells and inflammatory diseases. These contributions have paved the way for innovative approaches to drug development. Utilizing his expertise, he has successfully developed and characterized a diverse range of protein and cellular assays that enable in-depth investigations into immunity and inflammation. His research findings have been published in prestigious scientific journals, including Nature Communications, Cell Reports, Journal of the American Chemical Society, Diabetes, Journal of Medicinal Chemistry, and the British Journal of Pharmacology. His work has been highly cited, reflecting its impact and significance within the scientific community.
Recognized for his outstanding mentoring abilities, Junxian has supervised or co-supervised the research of two completed PhD students, six completed MPhil students, and three completed Honours students. The success of his former students is a testament to his dedication and guidance. They continue to excel and actively contribute to research endeavours around the world, spanning countries such as Australia, Singapore, Korea, India, Japan, and China.
Beyond his research and mentoring achievements, Junxian actively participates in the scientific community. He serves on the editorial boards of esteemed journals like Journal of Translational Medicine, Frontiers in Molecular Biosciences and Biology. This involvement allows him to stay at the forefront of scientific advancements and contribute to the dissemination of knowledge within his field.
ARC Centre of Excellence for Innovations in Peptide and Protein Science
Institute for Molecular Bioscience
Professorial Research Fellow
Australian Institute for Bioengineering and Nanotechnology
Affiliate Associate Professor
School of Chemistry and Molecular Biosciences
Faculty of Science
Affiliate Associate Professor
Institute for Molecular Bioscience
Availability:
Available for supervision
Media expert
Professor Mobli is a structural biologist and a group leader at the University of Queensland's Australian Institute for Bioengineering and Nanotechnology (AIBN). He is well known internationally for his contributions to the basic theory of multidimensional nuclear magnetic resonance and its applications to resolving the molecular structure of peptides and proteins, as well as studying their physiochemical properties and function. Mehdi's contributions to the field has been recognised by being appointed an Executive Editor of the AMPERE society's journal "Magnetic Resonance", and to the advisory board of the international Biological Magnetic Resonance Data Bank (BMRB) as well as serving on the board of directors of the Australia and New Zealand Society for Magnetic Resonance (ANZMAG). He is a former ARC Future Fellow and recipient of the ASBMB MERCK medal, the Australia Peptide Society's Tregear Award, the ANZMAG Sir Paul Callaghan medal and the Lorne Proteins Young Investigator Award (now Robin Anders Award).
Prof. Mobli's research group focuses on characterising the structure and function of receptors involved in neuronal signalling, with a particular focus on developing new approaches for the discovery and characterisation of modulators of these receptors through innovations in bioinformatics, biochemistry and and biophysics. This work has led to publication of more than 100 research articles attracting over 6,000 citations.
Associate Professor Muttenthaler is a medicinal chemist working at the interface of chemistry and biology with a strong passion for translational research. His research focuses on neuropeptides and the exploration of Nature's biodiversity to develop molecular tools, diagnostics, and therapeutics. His background in drug discovery and development, as well as his interdisciplinary training in the fields of chemistry, molecular biology and pharmacology, assist him in the characterisation of these highly potent and selective compounds and allow him to study their interactions with human physiology for medical innovations in pain, cancer, gut disorders and neurodegenerative diseases.
ARC Centre of Excellence for Innovations in Peptide and Protein Science
Institute for Molecular Bioscience
Affiliate Professor of School of Ch
School of Chemistry and Molecular Biosciences
Faculty of Science
Professorial Research Fellow and Gr
Australian Institute for Bioengineering and Nanotechnology
Availability:
Available for supervision
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Megan O’Mara is a Professor and Group Leader at the Australian Institute for Bioengineering and Nanotechnology (AIBN), UQ. Her group uses multiscale modelling techniques to understand how changes in the biochemical environment of the cell membranes alters membrane properties and modulates the function of membrane proteins. She has research interests in multidrug resistance, computational drug design and delivery, biopolymers, and personalized medicine. Megan completed her PhD in biophysics at the Australian National University in 2005 before moving to the University of Calgary, Canada, to take up a Canadian Institutes of Health Research Postdoctoral Fellowship. In 2009, she returned to Australia to join University of Queensland’s School of Chemistry and Molecular Biosciences as a UQ Postdoctoral Fellow, before commencing an ARC DECRA in 2012 where she continued her computational work on membrane protein dynamics. In 2015, Megan joined the Research School of Chemistry, Australian National University in 2015 as Rita Cornforth Fellow and Senior Lecturer. In 2019 she was promoted to Associate Professor and was Associate Director (Education) of the Research School of Chemistry ANU in 2019-2021. In April 2022 she relocated to AIBN.
Dr Robitaille works within a research team known as the Calcium Signalling Cancer Research Laboratory. This team research focus on identifying and validating new targets for drug development in cancer.
Queensland Alliance for Agriculture and Food Innovation
Availability:
Available for supervision
Media expert
Professor Eugeni Roura is a nutritionist by background with specific research interests in digestive physiology and chemosensory science. He joined the University of Queensland (UQ) in 2010 as a member of the Centre for Nutrition and Food Sciences, where he leads a research team active in the interface between basic and translational research aiming at industrial and societal applications. The main research interests include gut nutrient sensing mechanisms and appetite modulation (including taste and smell) relevant to humans, pigs and poultry. Recently, the research focus has evolved to include transgenerational nutrition studies including foetal development in pigs and “in ovo” applications in chickens. In 2011 he joined the UQ School of Biomedical Sciences as an Affiliated Lecturer.
Professor Roura graduated with a Veterinary Science degree from the Universitat Autonoma de Barcelona (UAB) before pursuing post-graduate studies in Nutrition at the University of California (UC Davis). After finishing a Post-Doctoral position at UC Davis, he started a sixteen-year industry career working for the feed and food industries in R&D and market-focused technical services, culminating as Group Deputy R&D Director of Lucta S.A.
He has authored more than 100 peer-reviewed scientific publications, and he has been invited as keynote speaker to ca 50 scientific meetings. He is currently serving as a member of the National Committee for Nutrition of the Australian Academy of Sciences, International Steering Committee of the Digestive Physiology of pigs, R&D and Education Committee of the Australasian Pork Research Institute Ltd., expert evaluator of 1 international and 2 national research grant programs, and as Editorial Board of two scientific journals ("Journal of Animal Science and Biotechnology" and "Animals"). Main past positions include President of the Austral-Asian Chemosensory Society, Vice-Chairperson of the Board Specialty Committee of Mongolian Medicine, Standards Australia FT-022 Committee “Sensory Analysis of Food”, Master of Dietetics Studies Engagement Committee (UQ), AgriFutures Chicken Meat Advisory Panel, and the European Feed Additive Federation (FEFANA) amongst others. In addition, Professor Eugeni Roura has been involved in several national and international conference organizing committees including acting as leading co-Chair of the Digestive Physiology of Pigs 2018.
Critical Care Medicine focuses on supporting patients, often with one or multiple organ failures. Based at the largest Australian cardiac hospital, our research investigates better ways to support patients with heart and/or lung failure. We explore technological, pharmacological and engineering advances that could help our patients to live longer and better. Our group is world-renowned for clinically relevant large animal models, including heart failure, respiratory failure (ARDS), heart transplantation, sepsis, cardiogenic shock, and more. All our studies use hospital-grade equipment and follow the same clinical guideline to maximise translation. We actively take on honours, MPhil and PhD students from multi-disciplinary backgrounds (science, engineering, medicine, allied health), with a successful track record in supporting our students to secure their own grants and funding. Students are expected to contribute to other studies of the group. For more information about the group, please visit ccrg.org.au, and email if you are interested to join us.
Australian Institute for Bioengineering and Nanotechnology
Availability:
Available for supervision
Dr Tosolini is a cell biologist with a focus at the intersection of axonal transport, neurotrophic factors, motor neurons and skeletal muscle, in the context of motor neuron disease (MND)/amyotrophic lateral sclerosis (ALS). His research to date has focused on utilising the connectivity between skeletal muscle and motor neurons for the enhanced delivery of therapeutic agents to the spinal cord (e.g., viral-mediated gene therapy). Building upon these foundations, his postdoctoral training focused on defining the axonal transport dynamics in a number of different experimental conditions, including stimulation with different neurotrophic factors (e.g., BDNF, GDNF), α motor neuron subtypes (i.e., fast motor neurons vs slow motor neurons), and alterations to such factors in MND/ALS pathology.
Dr Tosolini has joined the laboratories of A/Prof. Shyuan Ngo (AIBN) and Dr. Derek Steyn (SBMS) to undertake a novel project looking at assessing a novel therapeutic compound in mouse models of ALS, and in as well as in ALS patient-derived muscle cultures. This project is in collaboration with Dr. Giovanni Nardo at Laboratory of Molecular Neurobiology, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Dr Tosolini completed his PhD in 2015 in the discipline of Anatomy at the School of Medical Sciences, University of New South Wales (UNSW). His PhD project focused on characterising the connectivity between various skeletal muscles and their innervating motor neuron pools, to optimally deliver agents (e.g., retrograde tracers, virus) to the spinal cord motor neurons via retrograde axonal transport. For the work produced in his PhD, Dr Tosolini was awarded a place on the Faculty of Medicine's Dean's List.
In 2016, Dr Tosolini joined the Schiavo Laboratory at University College London (UCL), UK as a Post-Doctoral Research Associate to undertake a project focused on: 1) understanding factors influencing axonal transport dynamics in distinct in vitro and in vivo models of motor neuron disease (MND)/amyotrophic lateral sclerosis (ALS), and 2) revealing the signalling elements governing neuronal trans-synaptic transfer.
In 2020, Dr Tosolini was awarded a Junior Non-Clinical Post-Doctoral Fellowship by the Motor Neuron Disease Association, UK to expand his work on evaluating axonal transport dynamics in mouse models of motor neuron disease (MND) as well as in diverse human induced pluripotent stem cell (hiPSC)-derived motor neurons. This project is a direct continuation of my post-doctoral training in the Schiavo laboratory, and included a novel collaboration with Prof. Rickie Patani (Francis Crick Institute, London, UK), to evaluate axonal transport dynamics of diverse organelles in mouse and human models of MND/ALS.
My research interests are centred around the structure and function of venom and silk polypeptides produced by arthropods, and their use in biotechnology and medicine. I am a Postdoctoral Fellow in the King laboratory in the Institute for Molecular Bioscience, the University of Queensland, Australia. Currently, I am investigating the composition, function and evolution of neglected insect venoms produced by assassin bugs (Hemiptera: Reduviidae), robber flies (Diptera: Asilidae) and nettle caterpillars (Lepidoptera: Limacodidae).