Overview
Background
Dr Melanie Robitaille is a Senior Post-Doctoral Researcher working with the Calcium Signalling in Therapeutics Team (CaSTT) in the School of Pharmacy. This team specializes in the development and application of novel methodologies and cellular assays in drug discovery, including the use of genetically encoded indicator for high-content imaging in live cells.
Her interests are to elucidate how calcium signals are remodelled in disease states, to identify calcium transporters as new therapeutic targets and to develop molecular and cellular screening tools to be used in drug development programs. She has an established profile in cellular and molecular biology, with high expertise in plasmid cloning, lentiviral transduction and the use of CRISPR/Cas9 to modulate gene expression.
Availability
- Dr Melanie Robitaille is:
- Not available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, Université de Montréal
Works
Search Professor Melanie Robitaille’s works on UQ eSpace
2025
Journal Article
ORAI1α and ORAI1β have differential sensitivity to extracellular pH
Robitaille, Mélanie, McCullough, Michael H., So, Choon Leng, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2025). ORAI1α and ORAI1β have differential sensitivity to extracellular pH. Biochimica et Biophysica Acta. Molecular Cell Research, 1872 (7) 120010, 1-11. doi: 10.1016/j.bbamcr.2025.120010
2025
Journal Article
Cancer Progression and the Calcium Signaling Toolkit: Expanding Dimensions and Perspectives
Robitaille, Mélanie and Monteith, Gregory R. (2025). Cancer Progression and the Calcium Signaling Toolkit: Expanding Dimensions and Perspectives. Cold Spring Harbor Perspectives in Biology a041767, 1-17. doi: 10.1101/cshperspect.a041767
2025
Other Outputs
FLIPR raw data
Robitaille, Melanie, Roberts-Thomson, Sarah and Monteith, Gregory (2025). FLIPR raw data. The University of Queensland. (Dataset) doi: 10.48610/e3133eb
2024
Conference Publication
The effect of enhanced Ca2+ influx by IA65 on ORAI1-mediated Interleukin-6 gene expression in breast cancer cells
Han, Jihye, Forouz, Farzaneh, Roberts-Thomson, Sarah J., Monteith, Gregory R., Bong, Alice H. L. and Robitaille, Melanie (2024). The effect of enhanced Ca2+ influx by IA65 on ORAI1-mediated Interleukin-6 gene expression in breast cancer cells. ASCEPT, APFP & APSA Joint Conference, Melbourne, VIC, Australia, 1 - 4 December 2024.
2024
Conference Publication
Developing a cell-based model to assess the effect of intermittent dabrafenib exposure on melanoma cells
Nagarajan, Anika, Forouz, Farzaneh, Roberts-Thomson, Sarah J., Monteith, Gregory R., Schaider, Helmut and Robitaille, Melanie (2024). Developing a cell-based model to assess the effect of intermittent dabrafenib exposure on melanoma cells. ASCEPT, APFP & APSA Joint Conference, Melbourne, VIC, Australia, 1 - 4 December 2024.
2024
Conference Publication
Bivalent peptide agonists targeting peripheral Kappa and Nociceptin heterodimer opioid receptors for the treatment of pain and opioid use disorder
Habib, Muhaimin, Saifuddin, Danial, Robitaille, Mélanie and Cabot, Peter (2024). Bivalent peptide agonists targeting peripheral Kappa and Nociceptin heterodimer opioid receptors for the treatment of pain and opioid use disorder. ASCEPT, APFP & APSA Joint Conference, Melbourne, VIC Australia, 1 - 4 December 2024.
2024
Conference Publication
Targeting peripheral mu and delta heterodimer receptors with bivalent opioid peptides
Zhang, Junkai, Robitaille, Melanie, Saifuddin, Danial, Ross, Benjamin and Cabot, Peter (2024). Targeting peripheral mu and delta heterodimer receptors with bivalent opioid peptides. ASCEPT, APFP & APSA Joint Conference, Melbourne, VIC Australia, 1 - 4 December 2024.
2024
Journal Article
TMCO1 is upregulated in breast cancer and regulates the response to pro-apoptotic agents in breast cancer cells
Bong, Alice H. L., Robitaille, Mélanie, Lin, Sichun, McCart-Reed, Amy, Milevskiy, Michael, Angers, Stéphane, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2024). TMCO1 is upregulated in breast cancer and regulates the response to pro-apoptotic agents in breast cancer cells. Cell Death Discovery, 10 (1) 421, 1-12. doi: 10.1038/s41420-024-02183-0
2024
Conference Publication
Understanding changes in host cell calcium signalling during coronavirus infection
Chan, Shao Ming, Monteith, Gregory, Roberts-Thomson, Sarah, Labzin, Larisa and Robitaille, Mélanie (2024). Understanding changes in host cell calcium signalling during coronavirus infection. OPTIONS XII for the Control of Influenza, Brisbane, QLD Australia, 29 September - 2 October 2024.
2024
Conference Publication
ORAI1 isoforms have differential sensitivity to extracellular pH
Robitaille, Melanie, McCullough, Michael H., So, Choon Leng, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2024). ORAI1 isoforms have differential sensitivity to extracellular pH. BioMolecular Horizons 2024, Melbourne, VIC, Australia, 22-26 September 2024.
2024
Conference Publication
Calcium signaling in the breast cancer microenvironment
Forouz, Farzaneh, Bong, Alice H., Robitaille, Melanie, Roberts-Thomson, Sarah and Monteith, Gregory (2024). Calcium signaling in the breast cancer microenvironment. BioMolecular Horizons 2024, Melbourne, VIC Australia, 22-26 September 2024.
2024
Conference Publication
A high-throughput method to monitor live-cell calcium signalling changes during coronavirus infection.
Chan, Shao Ming, Monteith, Gregory, Roberts-Thomson, Sarah, Labzin, Larisa and Robitaille, Mélanie (2024). A high-throughput method to monitor live-cell calcium signalling changes during coronavirus infection.. 17th International Meeting of the European Calcium Society, Cambridge, United Kingdom, 31 August - 4 September 2024.
2024
Conference Publication
A calcium influx pathway regulates adaptive melanoma drug tolerance
Guan, Yimeng, Robitaille, Melanie, Torrano, Joachim, Haass, Nikolas, Roberts-Thomson, Sarah, Monteith, Gregory and Schaider, Helmut (2024). A calcium influx pathway regulates adaptive melanoma drug tolerance. ASDR 2024 Annual Scientific Meeting, Sydney, NSW Australia, 18-20 July 2024.
2024
Conference Publication
Exploring calcium signalling remodelling during adaptive cancer drug tolerance
Robitaille, Melanie, Schaider, Helmut, Monteith, Gregory and Roberts-Thomson, Sarah (2024). Exploring calcium signalling remodelling during adaptive cancer drug tolerance. Calcium Signaling- Gordon Research Conference, Barga, Lucca, Italy, 30 June - 5 July 2024.
2024
Journal Article
Cellular geometry and epithelial-mesenchymal plasticity intersect with PIEZO1 in breast cancer cells
So, Choon Leng, Robitaille, Mélanie, Sadras, Francisco, McCullough, Michael H., Milevskiy, Michael J. G., Goodhill, Geoffrey J., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2024). Cellular geometry and epithelial-mesenchymal plasticity intersect with PIEZO1 in breast cancer cells. Communications Biology, 7 (1) 467, 1-14. doi: 10.1038/s42003-024-06163-z
2023
Conference Publication
Developing a human cell model to study calcium signalling during coronavirus infection.
Chan, Shao Ming, Monteith, Gregory, Roberts-Thomson, Sarah, Labzin, Larisa and Robitaille, Mélanie (2023). Developing a human cell model to study calcium signalling during coronavirus infection.. ASCEPT Annual Scientific Meeting, Sydney, NSW, Australia, 20-23 November 2023.
2023
Conference Publication
Calcium signaling and the breast cancer microenvironment
Forouz, Farzaneh, Bong, Alice H. L., Gieniec, Krystyna A., Sadras, Francisco, Robitaille, Mélanie, Roberts- Thomson, Sarah J., Davis, Felicity M. and Monteith, Gregory R. (2023). Calcium signaling and the breast cancer microenvironment. ASCEPT Annual Scientific Meeting, Sydney, NSW Australia, 20-23 November 2023.
2023
Conference Publication
Gene expression of calcium signalling modulators in SARS-CoV-2 infection
Akison, Mia C., Eschke, Kathrin, Monteith, Gregory, Roberts-Thomson, Sarah, Labzin, Larisa and Robitaille, Mélanie (2023). Gene expression of calcium signalling modulators in SARS-CoV-2 infection. ASCEPT Annual Scientific, Sydney, NSW, Australia, 20-23 November 2023.
2023
Conference Publication
Exploring calcium signalling remodelling during adaptive cancer drug tolerance
Robitaille, Mélanie, Schaider, Helmut, Roberts-Thomson, Sarah and Monteith, Gregory (2023). Exploring calcium signalling remodelling during adaptive cancer drug tolerance. ASCEPT Annual Scientific Meeting, Sydney, NSW Australia, 20-23 November 2023.
2023
Journal Article
The intersection between cysteine proteases, Ca2+ signalling and cancer cell apoptosis
Hua, Trinh, Robitaille, Mélanie, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2023). The intersection between cysteine proteases, Ca2+ signalling and cancer cell apoptosis. Biochimica et Biophysica Acta - Molecular Cell Research, 1870 (7) 119532, 1-13. doi: 10.1016/j.bbamcr.2023.119532
Supervision
Availability
- Dr Melanie Robitaille is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
The intersection between calcium signaling pathways and coronavirus infection
Principal Advisor
Other advisors: Professor Gregory Monteith, Dr Larisa Labzin
-
Doctor Philosophy
Designing novel bivalent ligands that target the Kappa and nociceptin opioid receptors for reduced side effects
Associate Advisor
Other advisors: Dr Rink-Jan Lohman, Dr Danial Saifuddin, Professor Peter Cabot
-
Doctor Philosophy
Engineering a recombinant targeted delivery platform for nucleic acid-based therapeutics
Associate Advisor
Other advisors: Associate Professor Peter Moyle
-
Doctor Philosophy
Targeting peripheral kappa and mu bivalent opioid receptors with bivalent opioid peptides for inflammatory pain
Associate Advisor
Other advisors: Dr Ben Ross, Dr Danial Saifuddin, Professor Peter Cabot
-
Master Philosophy
Characterisation of novel Dynorphin analogues targeting KOP receptors
Associate Advisor
Other advisors: Dr Danial Saifuddin, Professor Peter Cabot
Completed supervision
-
2025
Doctor Philosophy
Calcium signalling in the context of cell-in-cell structures in a model of entosis in breast cancer cells
Associate Advisor
Other advisors: Professor Gregory Monteith
-
2022
Doctor Philosophy
Shape- and matrix-density mediated changes in calcium signalling in breast cancer cells
Associate Advisor
Other advisors: Professor Gregory Monteith
Media
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