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2015

Conference Publication

Serum adipokines in response to venesection in patients with non-alcoholic fatty liver disease

Britton, L., Bridle, K., Reiling, J., Santrampurwala, N., Wockner, L., Ching, H., Subramaniam, V., Crawford, D. and Adams, L. (2015). Serum adipokines in response to venesection in patients with non-alcoholic fatty liver disease. Gastro 2015 GESA-AGW and WGO International Congress, Brisbane, Queensland, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13087

Serum adipokines in response to venesection in patients with non-alcoholic fatty liver disease

2015

Conference Publication

Next-generation sequencing: application of a novel platform to the analysis of atypical iron disorders

Mcdonald, C. J., Ostini, L., Wallace, D. F., Lyons, A., Crawford, D. H. G. and Subramaniam, V. N. (2015). Next-generation sequencing: application of a novel platform to the analysis of atypical iron disorders. Gastro 2015 GESA‐AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 | World Congress of Gastroenterology, Brisbane, QLD, Australia, 28 September - 2 October 2015. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia.

Next-generation sequencing: application of a novel platform to the analysis of atypical iron disorders

2015

Conference Publication

Free fatty acid treatment reduces BMP6 signalling in AML12 hepatocytes

Santrampurwala, N., Bridle, K. R., Reiling, J., Britton, L. J., Jaskowski, L. A., Subramaniam, V. N. and Crawford, D. H. G. (2015). Free fatty acid treatment reduces BMP6 signalling in AML12 hepatocytes. Gastro 2015 GESA-AGW and WGO International Congress, Brisbane, Queensland, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13087

Free fatty acid treatment reduces BMP6 signalling in AML12 hepatocytes

2015

Conference Publication

A physiologically based kinetic model to characterize and predict the biological fate of circulating tumor cells in vivo

Wang, H., Liang, X., Thorling, C., Xu, Z. P., Crawford, D., Liu, X. and Roberts, M. (2015). A physiologically based kinetic model to characterize and predict the biological fate of circulating tumor cells in vivo. European Cancer Congress, Vienna, Austria, 2015. Hoboken, NJ United States: Wiley. doi: 10.1016/S0959-8049(15)30013-7

A physiologically based kinetic model to characterize and predict the biological fate of circulating tumor cells in vivo

2014

Conference Publication

Hepatic microRNA expression is altered in a murine model of iron and fat co-mediated liver injury

Mcdonald, C. J., Yuan, Y., Santrampurwala, N., Crawford, D. H. G. and Subramaniam, V. N. (2014). Hepatic microRNA expression is altered in a murine model of iron and fat co-mediated liver injury. HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/jgh.12736_5

Hepatic microRNA expression is altered in a murine model of iron and fat co-mediated liver injury

2014

Conference Publication

The potential role of lipopolysaccharides in the development of biliary injury in an animal partial liver ischemia model

Reiling, J., Bridle, K. R., Santrampurwala, N., Britton, L. J., Crawford, D. H. G., Dejong, C. H. C. and Fawcett, J. (2014). The potential role of lipopolysaccharides in the development of biliary injury in an animal partial liver ischemia model. HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/jgh.12736_8

The potential role of lipopolysaccharides in the development of biliary injury in an animal partial liver ischemia model

2014

Conference Publication

Safety of ABT-450/r/Ombitasvir plus Dasabuvir With or Without Ribavirin in HCV Genotype 1-infected Patients >= 65 Years of Age: Results From Phase 2 and 3 Trials

Flamm, Steven L., Gane, Edward J., DuFour, Jean-Francois J., Rustgi, Vinod, Bain, Vincent G., Crawford, Darrell H., Andreone, Pietro, Hassanein, Tarek, Mazur, Wlodzimierz W., Lovell, Sandra S., Da Silva-Tillmann, Barbara, Shulman, Nancy, Puoti, Massimo, Box, Terry D. and Jacobson, Ira M. (2014). Safety of ABT-450/r/Ombitasvir plus Dasabuvir With or Without Ribavirin in HCV Genotype 1-infected Patients >= 65 Years of Age: Results From Phase 2 and 3 Trials. 65th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, Massachusetts, 7-11 November 2014. Hoboken, NJ, United States: John Wiley & Sons.

Safety of ABT-450/r/Ombitasvir plus Dasabuvir With or Without Ribavirin in HCV Genotype 1-infected Patients >= 65 Years of Age: Results From Phase 2 and 3 Trials

2014

Conference Publication

ABT-450/r/Ombitasvir plus Dasabuvir With or Without Ribavirin in HCV Genotype 1-infected Patients with History of Depression or Bipolar Disorder: Pooled Analysis of Efficacy and Safety in Phase 3 Trials

Nelson, David R., Reddy, K. Rajender, Di Bisceglie, Adrian M., Ferenci, Peter, Crawford, Darrell H., Stauber, Rudolf E., Yakovlev, Alexey A., de Ledinghen, Victor, Hinrichsen, Holger, Bernstein, David Eric, de Knegt, Robert J., Hassanein, Tarek, Norris, Suzanne, Xiong, Junyuan J., McGovern, Barbara H. and Agarwal, Kosh (2014). ABT-450/r/Ombitasvir plus Dasabuvir With or Without Ribavirin in HCV Genotype 1-infected Patients with History of Depression or Bipolar Disorder: Pooled Analysis of Efficacy and Safety in Phase 3 Trials. 65th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, Massachusetts, 7-11 November 2014 . Hoboken, NJ, United States: John Wiley & Sons.

ABT-450/r/Ombitasvir plus Dasabuvir With or Without Ribavirin in HCV Genotype 1-infected Patients with History of Depression or Bipolar Disorder: Pooled Analysis of Efficacy and Safety in Phase 3 Trials

2014

Conference Publication

Successful ex-vivo normothermic oxygenated machine perfusion of human donor livers

Reiling, J., Lockwood, D. S. R., Simpson, A. H., Campbell, C. M., Bridle, K. R., Santrampurwala, N., Britton, L. J., Crawford, D. H. G., Dejong, C. H. C. and Fawcett, J. (2014). Successful ex-vivo normothermic oxygenated machine perfusion of human donor livers. 65th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, United States, 7 - 11 November 2014. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia.

Successful ex-vivo normothermic oxygenated machine perfusion of human donor livers

2013

Conference Publication

Interleukin-28B rs12979860 C allele is protective against advanced fibrosis in chronic he[atotos C genotype 1 infection: analysis of the Australasian Chariot Study Cohort

Kitson, M. T., Dore, G. J., George, J., Button, P., McCaughan, G. W., Crawford, D. H., Sievert, W., Weltman, M. D., Cheng, W. S. and Roberts, S. K. (2013). Interleukin-28B rs12979860 C allele is protective against advanced fibrosis in chronic he[atotos C genotype 1 infection: analysis of the Australasian Chariot Study Cohort. International Liver Congress / 48th Annual Meeting of the European Association for the Study of the Liver (EASL), Amsterdam Netherlands, 24-28 April 2013. Amsterdam, The Netherlands: Elsevier BV. doi: 10.1016/S0168-8278(13)60468-7

Interleukin-28B rs12979860 C allele is protective against advanced fibrosis in chronic he[atotos C genotype 1 infection: analysis of the Australasian Chariot Study Cohort

2013

Conference Publication

The impact of phlebotomy in non-alcoholic fatty liver disease: interim results of a randomized controlled trial

Adams, Leon, House, Michael J., St Pierre, Timothy G., Crawford, Darrell H., Stuart, Katherine A., Ching, Helena, Kava, Jenny, Webb, Malcolm and Olynyk, John K. (2013). The impact of phlebotomy in non-alcoholic fatty liver disease: interim results of a randomized controlled trial. 64th Annual Meeting and Postgraduate Course of the American Association for the Study of Liver Diseases, Washington Dc, 01 - 05 November, 2013. Hoboken, NJ United States: John Wiley and Sons, Inc.. doi: 10.1002/hep.26849

The impact of phlebotomy in non-alcoholic fatty liver disease: interim results of a randomized controlled trial

2013

Conference Publication

New genetic complexity underlying atypical iron disorders

McDonald, C. J., Wallace, D. F., Crawford, D. H. and Subramaniam, V. N. (2013). New genetic complexity underlying atypical iron disorders. Australian Gastroenterology Week 2013, Melbourne, Australia, 7-9 October 2013. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

New genetic complexity underlying atypical iron disorders

2013

Conference Publication

Impaired iron uptake in Mdr2(-/-) mice results in hepatic iron deficiency: implications for patients with cholestatic liver injury

Sobbe, A. L., Frazer, D. M., Bridle, K. R., Jaskowski, L. A., Anderson, G. J., Subramaniam, V. N. and Crawford, D. H. (2013). Impaired iron uptake in Mdr2(-/-) mice results in hepatic iron deficiency: implications for patients with cholestatic liver injury. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

Impaired iron uptake in Mdr2(-/-) mice results in hepatic iron deficiency: implications for patients with cholestatic liver injury

2013

Conference Publication

Isolated Hepatic Iron Deficiency Despite Abundant Systemic Iron in Mdr2-/- Mice: Integrity of the Biliary Transport System Is Important in Liver Iron Homeostasis

Sobbe, Amy, Frazer, David, Bridle, Kim, Jaskowski, Lesley, Ostini, Lesa, de Guzman, Erika, Santrampurwala, Nishreen, Anderson, Gregory, Subramaniam, V. Nathan and Crawford, Darrell (2013). Isolated Hepatic Iron Deficiency Despite Abundant Systemic Iron in Mdr2-/- Mice: Integrity of the Biliary Transport System Is Important in Liver Iron Homeostasis. 5th Meeting of the International BioIron Society, University College London UK, 14 - 18 May 2013. Hoboken, NJ United States: John Wiley and Sons, Inc. doi: 10.1002/ajh.23453

Isolated Hepatic Iron Deficiency Despite Abundant Systemic Iron in Mdr2-/- Mice: Integrity of the Biliary Transport System Is Important in Liver Iron Homeostasis

2013

Conference Publication

An iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe(-/-) mice

Wilkinson, A. S., Bridle, K. R., Britton, L. J., Jaskowski, L. A., Fletcher, L. M., Subramaniam, V. N. and Crawford, D. H. G. (2013). An iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe(-/-) mice. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

An iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe(-/-) mice

2013

Conference Publication

Hfe-associated steatohepatitis: Expression profiling and identifying the molecular basis of liver injury

Santrampurwala, N., Bridle, K. R., Heritage, M. L., Jaskowski, L. A., Wilkinson, A. S., Subramaniam, V. N. and Crawford, D. H. G. (2013). Hfe-associated steatohepatitis: Expression profiling and identifying the molecular basis of liver injury. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

Hfe-associated steatohepatitis: Expression profiling and identifying the molecular basis of liver injury

2013

Conference Publication

Heterozygous Deletion of the Hfe Gene Contributes to Hepatic Iron Loading But Not Steatosis in Mice Fed a High Fat Diet

Britton, Laurence, Jaskowski, Lesley, Wilkinson, Ashley, Bridle, Kim, Subramaniam, Nathan and Crawford, Darrell (2013). Heterozygous Deletion of the Hfe Gene Contributes to Hepatic Iron Loading But Not Steatosis in Mice Fed a High Fat Diet. 5th Meeting of the International BioIron Society, University College London UK, 14 - 18 May 2013. Hoboken, NJ United States: John Wiley and Sons, Inc. doi: 10.1002/ajh.23453

Heterozygous Deletion of the Hfe Gene Contributes to Hepatic Iron Loading But Not Steatosis in Mice Fed a High Fat Diet

2013

Conference Publication

Administration of an iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe-/- mice

Wilkinson, Ashley S., Bridle, Kim, Britton, Laurence, Jaskowski, Lesley, Fletcher, Linda M., Subramaniam, V. Nathan and Crawford, Darrell H. (2013). Administration of an iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe-/- mice. 64th Annual Meeting and Postgraduate Course of the American Association for the Study of Liver Diseases, Washington, DC, United States, 1 - 5 November 2013. Hoboken, NJ, United States: John Wiley & Sons.

Administration of an iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe-/- mice

2013

Conference Publication

Heterozygous Hfe (haemochromatosis) gene deletion contributes to hepatic iron loading but not steatosis in mice fed a high fat diet

Britton, L., Jaskowski, L., Wilkinson, A., Bridle, K., Subramaniam, N. and Crawford, D. (2013). Heterozygous Hfe (haemochromatosis) gene deletion contributes to hepatic iron loading but not steatosis in mice fed a high fat diet. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

Heterozygous Hfe (haemochromatosis) gene deletion contributes to hepatic iron loading but not steatosis in mice fed a high fat diet

2012

Conference Publication

Deferasirox does not exhibit antifibrotic activity when administered to Mdr2-/- mice

Sobbe, Amy, Bridle, Kim, de Guzman, Cloe Erika, Santrampurwala, Nishreen, Subramaniam, Nathan and Crawford, Darrell H. (2012). Deferasirox does not exhibit antifibrotic activity when administered to Mdr2-/- mice. Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, Vic., Australia: Wiley-Blackwell Publishing. doi: 10.1111/j.1440-1746.2011.07251.x

Deferasirox does not exhibit antifibrotic activity when administered to Mdr2-/- mice