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2012

Conference Publication

Application of next-generation sequencing technology to diagnosis of genetic iron disorders

McDonald, Cameron, Wallace, Daniel, Crawford, Darrell H. and Subramaniam, Nathan (2012). Application of next-generation sequencing technology to diagnosis of genetic iron disorders. Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/j.1440-1746.2011.07251.x

Application of next-generation sequencing technology to diagnosis of genetic iron disorders

2012

Conference Publication

Curcumin and vitamin E combination treatment reduces the severity of disease in a diet-induced mouse model of NAFLD

Wilkinson, Ashley S., Heritage, Mandy L., Jaskowski, Lesley A., Britton, Laurence J., Tan, Terrence C., Clouston, Andrew, Bridle, Kim, Macdonald, Graeme A., Anderson, Gregory, Fletcher, Linda M., Subramaniam, Nathan and Crawford, Darrell H. (2012). Curcumin and vitamin E combination treatment reduces the severity of disease in a diet-induced mouse model of NAFLD. Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, Vic., Australia: Wiley-Blackwell Publishing. doi: 10.1111/j.1440-1746.2011.07251.x

Curcumin and vitamin E combination treatment reduces the severity of disease in a diet-induced mouse model of NAFLD

2012

Conference Publication

The progression of NAFLD to NASH in a mouse model of Hfe(-/-)- associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E

Heritage, Mandy, Jaskowski, Lesley, Wilkinson, Ashley S., Britton, Laurence, Tan, Terrence C., Clouston, Andrew D., Bridle, Kim, Anderson, Gregory J., Macdonald, Graeme A., Fletcher, Linda M., Subramaniam, V. Nathan and Crawford, Darrell H. (2012). The progression of NAFLD to NASH in a mouse model of Hfe(-/-)- associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E. 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), Boston MA., United States, 9-13 November 2012. Hoboken, NJ United States: John Wiley and Sons. doi: 10.1002/hep.26040

The progression of NAFLD to NASH in a mouse model of Hfe(-/-)- associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E

2012

Conference Publication

Vitamin D Status Is Associated with Complete Evr But Not Svr in Chronic Hepatitis C Genotype 1 Infection: Analysis of the Australasian Chariot Study Cohort

Kitson, MT, Dore, GJ, Button, P, McCaughan, G, Crawford, D, Sievert, W, Weltman, M, Cheng, W, Roberts, SK and Chariot (2012). Vitamin D Status Is Associated with Complete Evr But Not Svr in Chronic Hepatitis C Genotype 1 Infection: Analysis of the Australasian Chariot Study Cohort. 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Barcelona Spain, Apr 18-22, 2012. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(12)61138-6

Vitamin D Status Is Associated with Complete Evr But Not Svr in Chronic Hepatitis C Genotype 1 Infection: Analysis of the Australasian Chariot Study Cohort

2012

Conference Publication

The progression of NAFLD to NASH in a mouse model of Hfe(-/-)-associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E

Heritage, Mandy L., Wilkinson, Ashley S., Jaskowski, Lesley A., Britton, Laurence J., Tan, Terrence C., Bridle, Kim, Clouston, Andrew, Anderson, Gregory, Fletcher, Linda M., Macdonald, Graeme A., Subramaniam, Nathan and Crawford, Darrell H. (2012). The progression of NAFLD to NASH in a mouse model of Hfe(-/-)-associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E. Abstracts of the Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/j.1440-1746.2011.07251.x

The progression of NAFLD to NASH in a mouse model of Hfe(-/-)-associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E

2012

Conference Publication

Iron toxicity impairs autophagy and promotes ER stress in obesity and alcohol-induced fibrosing steatohepatitis

Tan, Terrence C., Crawford, Darrell H., Jaskowski, Lesley A., Murphy, Therese L., Santrampurwala, Nishreen, Heritage, Mandy L., Subramaniam, Nathan, Clouston, Andrew, Crane, Denis I., Anderson, Gregory and Fletcher, Linda M. (2012). Iron toxicity impairs autophagy and promotes ER stress in obesity and alcohol-induced fibrosing steatohepatitis. Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, Vic., Australia: Wiley-Blackwell Publishing. doi: 10.1111/j.1440-1746.2011.07251.x

Iron toxicity impairs autophagy and promotes ER stress in obesity and alcohol-induced fibrosing steatohepatitis

2012

Conference Publication

Iron Toxicity Impairs Autophagy and Promotes ER Stress in Obesity and Alcohol-Induced Fibrosing Steatohepatitis

Tan, Terrence C., Crawford, Darrell H., Jaskowski, Lesley, Santrampurwala, Nishreen, Heritage, Mandy, Subramaniam, V. Nathan, Clouston, Andrew D., Crane, Denis I., Anderson, Gregory J. and Fletcher, Linda M. (2012). Iron Toxicity Impairs Autophagy and Promotes ER Stress in Obesity and Alcohol-Induced Fibrosing Steatohepatitis. 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), Boston, MA, United States, 9-13 November 2012. Hoboken, NJ, United States: John Wiley and Sons. doi: 10.1002/hep.26040

Iron Toxicity Impairs Autophagy and Promotes ER Stress in Obesity and Alcohol-Induced Fibrosing Steatohepatitis

2012

Conference Publication

Deferasirox does not exhibit antifibrotic activity when administered to Mdr2-/- mice

Sobbe, Amy, Bridle, Kim, de Guzman, Cloe Erika, Santrampurwala, Nishreen, Subramaniam, Nathan and Crawford, Darrell H. (2012). Deferasirox does not exhibit antifibrotic activity when administered to Mdr2-/- mice. Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, Vic., Australia: Wiley-Blackwell Publishing. doi: 10.1111/j.1440-1746.2011.07251.x

Deferasirox does not exhibit antifibrotic activity when administered to Mdr2-/- mice

2011

Conference Publication

Hepatic regeneration is not impaired in the Mdr2(-/-) mouse model of cholestasis

Hsu, L., Sobbe, A. L., Jaskowski, L., De Guzman, C. E., Santrampurwala, N., Bridle, K. R. and Crawford, D. H. (2011). Hepatic regeneration is not impaired in the Mdr2(-/-) mouse model of cholestasis. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

Hepatic regeneration is not impaired in the Mdr2(-/-) mouse model of cholestasis

2011

Conference Publication

The protective effects of corn-oil diet against alcohol and iron-induced hepatotoxicity in a mouse model of hemochromatosis

Tan, T., Crawford, D. H., Jaskowski, L., Murphy, T. L., Subramaniam, V. N. and Fletcher, L. M. (2011). The protective effects of corn-oil diet against alcohol and iron-induced hepatotoxicity in a mouse model of hemochromatosis. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL. doi: 10.1002/hep.24666

The protective effects of corn-oil diet against alcohol and iron-induced hepatotoxicity in a mouse model of hemochromatosis

2011

Conference Publication

Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice suggests a liver-specific alteration in iron metabolism

Sobbe, A. L., Bridle, K. R., Jaskowski, L. A., Ostini, L., De Guzman, C. E., Santrampurwala, N., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. (2011). Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice suggests a liver-specific alteration in iron metabolism. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice suggests a liver-specific alteration in iron metabolism

2011

Conference Publication

Lack of efficacy of rapamycin as an antifibrotic agent in the Mdr2(-/-) model of liver fibrosis

Bridle, K. R., Sobbe, A., Jaskowski, L., De Guzman, C. E., Santrampurwala, N., Fletcher, L. and Crawford, D. H. (2011). Lack of efficacy of rapamycin as an antifibrotic agent in the Mdr2(-/-) model of liver fibrosis. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

Lack of efficacy of rapamycin as an antifibrotic agent in the Mdr2(-/-) model of liver fibrosis

2011

Conference Publication

Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice: Integrity of the bile transport system is important in normal liver iron homeostasis

Sobbe, A., Bridle, K., Jaskowski, L., Ostini, L., de Guzman, C. E., Santrampurwala, N., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. (2011). Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice: Integrity of the bile transport system is important in normal liver iron homeostasis. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco, CA, United States, 4-8 November 2011. Malden MA United States: Wiley-Blackwell Publishing.

Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice: Integrity of the bile transport system is important in normal liver iron homeostasis

2011

Conference Publication

Hepatocellular carcinoma in an Australian tertiary hospital: No evidence of detection at an earlier stage over the past 10-years

Woodward, A. J., Miller, L. J., Fawcett, J., Crawford, D. H. G. and Stuart, K. A. (2011). Hepatocellular carcinoma in an Australian tertiary hospital: No evidence of detection at an earlier stage over the past 10-years. Unknown, unknown, unknown. MALDEN: WILEY-BLACKWELL.

Hepatocellular carcinoma in an Australian tertiary hospital: No evidence of detection at an earlier stage over the past 10-years

2011

Conference Publication

Altered lipid metabolism in HFE-knockout mice promotes severe NAFLD and early fibrosis

Tan, Terrence C. H., Crawford, Darrell H. G., Jaskowski, Lesley A., Murphy, Therese M., Heritage, Mandy L., Subramaniam, V. Nathan, Clouston, Andrew D., Anderson, Gregory J. and Fletcher, Linda M. (2011). Altered lipid metabolism in HFE-knockout mice promotes severe NAFLD and early fibrosis. Australian Gastroenterology Week 2011, Brisbane, Australia, 12-15 September 2011. MALDEN: WILEY-BLACKWELL.

Altered lipid metabolism in HFE-knockout mice promotes severe NAFLD and early fibrosis

2011

Conference Publication

Early On-Treatment Plasma Ribavirin Concentrations Are Associated with On-Treatment Anaemia and Treatment Outcome in Chronic Hepatitis C Genotype 1 Patients

Ali, R. J., Roberts, S. K., Ray, J., Sievert, W., McCaughan, G., Weltman, M., Crawford, D., Cheng, W., Rawlinson, W., Thommes, J., Rizkalla, B., Yoshihara, M., Dore, G. J., Matthews, G. V. and Chariot Study Grp (2011). Early On-Treatment Plasma Ribavirin Concentrations Are Associated with On-Treatment Anaemia and Treatment Outcome in Chronic Hepatitis C Genotype 1 Patients. 46th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Berlin Germany, 2011. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(11)60403-0

Early On-Treatment Plasma Ribavirin Concentrations Are Associated with On-Treatment Anaemia and Treatment Outcome in Chronic Hepatitis C Genotype 1 Patients

2011

Conference Publication

Evolution of hepatic fibrosis in Mdr2(-/-): Distinct temporal expression of fibrogenic mediators

Marbach, J., Sobbe, A. L., Jaskowski, L., De Guzman, C. E., Santrampurwala, N., Bridle, K. R. and Crawford, D. H. (2011). Evolution of hepatic fibrosis in Mdr2(-/-): Distinct temporal expression of fibrogenic mediators. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

Evolution of hepatic fibrosis in Mdr2(-/-): Distinct temporal expression of fibrogenic mediators

2011

Conference Publication

The Altered Expression of Iron Metabolism Genes in Models of Liver Injury Suggests Iron Deficiency in Cholestasis and Inappropriate Regulation of Hepcidin in Hepatocellular Cirrhosis

Heritage, M., Stuart, K. A., Bridle, K., Murphy, T. L., Sobbe, A., Jaskowski, L., Ostini, L., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. (2011). The Altered Expression of Iron Metabolism Genes in Models of Liver Injury Suggests Iron Deficiency in Cholestasis and Inappropriate Regulation of Hepcidin in Hepatocellular Cirrhosis. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco, CA, United States, 4-8 November 2011. Malden MA United States: Wiley-Blackwell Publishing.

The Altered Expression of Iron Metabolism Genes in Models of Liver Injury Suggests Iron Deficiency in Cholestasis and Inappropriate Regulation of Hepcidin in Hepatocellular Cirrhosis

2011

Conference Publication

The altered expression of iron metabolism genes in models of liver injury suggests iron deficiency in cholestasis and inappropriate regulation of hepcidin in hepatocellular cirrhosis

Heritage, M. L., Stuart, K. A., Bridle, K. R., Murphy, T. L., Sobbe, A. L., Jaskowski, L. A., Ostini, L., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. G. (2011). The altered expression of iron metabolism genes in models of liver injury suggests iron deficiency in cholestasis and inappropriate regulation of hepcidin in hepatocellular cirrhosis. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

The altered expression of iron metabolism genes in models of liver injury suggests iron deficiency in cholestasis and inappropriate regulation of hepcidin in hepatocellular cirrhosis

2010

Conference Publication

Efficacy of tenofovir disoproxil fumarate treatment in patients with a suboptimal response to adefovir dipivoxil

Sievert, W., George, J., Strasser, S. I., Crawford, D., Heathcote, E. J., Marcellin, P., Elsome, A. M., Sorbel, J. and Rousseau, F. (2010). Efficacy of tenofovir disoproxil fumarate treatment in patients with a suboptimal response to adefovir dipivoxil. unknown, unknown, unknown. MALDEN: WILEY-BLACKWELL PUBLISHING, INC.

Efficacy of tenofovir disoproxil fumarate treatment in patients with a suboptimal response to adefovir dipivoxil