Affiliate Professor of School of Biomedical Sciences
School of Biomedical Sciences
Faculty of Health, Medicine and Behavioural Sciences
Centre Director of The Centre for Cell Biology of Chronic Disease
Centre for Cell Biology of Chronic Disease
Institute for Molecular Bioscience
Centre Director of Institute for Molecular Bioscience
Institute for Molecular Bioscience
NHMRC Leadership Fellow - GL
Institute for Molecular Bioscience
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Available for supervision
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Brett Collins is an NHMRC Career Development Fellow and head of the Molecular Trafficking Lab at UQ's Institute for Molecular Bioscience. He was a lead investigator in the seminal structural studies of AP2, the protein adaptor molecule central to clathrin-mediated endocytosis, and has since defined the molecular basis for the function of critical proteins regulating membrane trafficking and signalling at the endosome organelle. His team is now focused on understanding how discrete molecular interactions between proteins and lipids control these processes in human cells.
Associate Professor Collins was awarded his PhD in 2001 and has published over 75 papers including in Cell, Nature, Nature Structural and Molecular Biology, Developmental Cell, and The Proceedings of the National Academy of Sciences USA, altogether cited more than 3100 times. He is the recipient of 3 prestigious fellowships, including a previous Career Development Award from the National Health and Medical Research Council and a Future Fellowship from the Australian Research Council, and was awarded the University of Queensland Research Excellence Award in 2008. In 2015 he was awarded the Emerging Leader Award of the ANZSCDB and in 2016 the Merck Research Medal from the ASBMB. He is currently the President of the Queensland Protein Group.
Dr Peter Collins is a Senior Dietitian at Mater Health in Brisbane, where he covers patient caseloads across gastroenterology and general medicine in both the public and private hospitals. Peter is a UK trained Registered Dietitian (RD) and an Accredited Practising Dietitian (APD) with a PhD in Clinical Nutrition from the Faculty of Medicine at The University of Southampton (June 2013). Peter’s research interests are around the detection and management of disease-related malnutrition, with a specific interest in the nutritional management of chronic obstructive pulmonary disease (COPD).
Peter is on the editorial board of the Journal of Human Nutrition and Dietetics and was recently awarded an appointment to the European Society for Clinical Nutrition and Metabolism (ESPEN) Faculty as an Early Career member. He is regularly invited to present at international conferences on the topic of malnutrition and nutrition support and has taught as part of the prestigious Life-Long Learning (LLL) international program in Clinical Nutrition and Metabolism for health care professionals including doctors, dietitians, nurses and pharmacists.
Faculty of Health, Medicine and Behavioural Sciences
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David is a Consultant Paediatrician, Metabolic Physician, Clinical Geneticist and clinician researcher. His area of expertise is the diagnosis and management of children with rare diseases. David is involved in multiple ongoing research projects aimed at novel disease discovery, improved diagnostic testing and treatments for children with inherited genetic disorders. He is director of a national clinic for Ataxia Telangiectasia brashat.org.au and has recently been awarded a $2.5 million NHMRC research grant for a phase 2/3 trial for treatment of this disorder.
Faculty of Health, Medicine and Behavioural Sciences
Affiliate of Queensland Cerebral Palsy Rehabilitation and Research Centre
Queensland Cerebral Palsy Rehabilitation and Research Centre
Faculty of Health, Medicine and Behavioural Sciences
Professorial Research Fellow
Centre for Health Services Research
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Not available for supervision
Professor Tracy Comans, a UQ Amplify Fellow at the Centre for Health Services Research, University of Queensland, and an Adjunct Research Fellow at the Royal Brisbane and Women’s Hospital, is renowned for her innovative application of economics in multifaceted health services contexts. Her pioneering work involves the creation of comprehensive models that extend beyond traditional economic models, enabling a broader assessment of benefits and costs.
In addition to her model development, Professor Comans applies these economic models to explore the cost-effectiveness of various health care interventions. She spearheads and cultivates health services research with a particular focus on older individuals, allied health, and rehabilitation services.
With a solid academic foundation in both physiotherapy and economics (Hons), Professor Comans brings a unique perspective to her research. Her clinical background as a physiotherapist, specializing in aged care, dementia, and rehabilitation, further enriches her work. Her expertise was recognized with a NHMRC Boosting Dementia Fellowship, which she held from 2017 to 2021.
Currently, Professor Comans is making significant strides in measuring the quality of care for older individuals. This work holds substantial potential for impacting the health and aged care industry. As our population ages, the demand for high-quality health care services tailored to the needs of older individuals is escalating. Despite this, there is a lack of agreement on what constitutes quality care for this demographic, and existing measures may not fully capture the aspects of care most important to them. Professor Comans’ work is instrumental in addressing this critical issue.
Affiliate of Centre for the Business and Economics of Health
Centre for the Business and Economics of Health
Faculty of Business, Economics and Law
Affiliate of Centre for Innovation in Pain and Health Research (CIPHeR)
Centre for Innovation in Pain and Health Research
Faculty of Health, Medicine and Behavioural Sciences
Professor - CBEH
Centre for the Business and Economics of Health
Faculty of Business, Economics and Law
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Available for supervision
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Luke Connelly is Professor of Health Economics at the Centre for the Business and Economics of Health. He also holds a Professorial appointment (part-time) at The University of Bologna, to which he was appointed in 2017 via the Italian “Direct Call” (link) process. In 2019 he was appointed as Honorary Professor at The University of Sydney. His main interests are in health economics and insurance economics and the effects of institutions (including legal constructs) on incentives and behaviour. He has also worked in other fields of applied microeconomics, including education economics and transport economics. His publications include papers in Review of Income and Wealth, Health Economics, Journal of Health Economics, Journal of Risk and Insurance, Geneva Papers on Risk and Insurance, Accident Analysis and Prevention, Journal of Law and Medicine, Journal of Clinical Epidemiology, European Journal of Health Economics, International Journal of Health Economics and Finance, Social Science and Medicine, Economic Papers, Economic Analysis and Policy, Journal of Transport Economics and Policy, Labour Economics, Economics and Human Biology as well as in a range of clinical journals, including Lancet.
Luke has served on a number of public committees including the Medical Services Advisory Committee (MSAC), which advises the Australian Minister for Health on the safety, efficacy, effectiveness, and cost-effectiveness of new and extant listings on Australia's Medicare Benefits Schedule. He has extensive service on other public committees and taskforces as well as extensive teaching and consulting engagements with industry. Over his career he has been a chief investigator on research grants and contracts totalling more than $67m. He is a member of the Editorial Boards of European Journal of Health Economics and the International Journal on Environmental Research and Public Health. He is a member of the International Health Economics Association's Arrow Awards Committee, which awards an annual prize in honour of Nobel Laureate Kenneth Arrow for the best paper in the field. He is currently Guest Editor (with Christophe Courbage) on a Special Issue of the Geneva Papers on Risk and Insurance on Insurance and Emerging Health Risks.
His current research interests include health service innovations to improve the health of people with chronic kidney disease(CKD). Ongoing interests include the economics of disability and insurance, compensable injury compensation schemes, and the determinants of health. Luke enjoys and has considerable experience teaching economics and health economics at both the graduate and undergraduate levels. In 2014 he was awarded the School of Economics Distinguished Teaching Award for his teaching on UQ's Master of Health Economics Program. In July 2016 and July 2019 he also taught summer schools in Health Economics and the Economics of Insurance at The University of Lucerne, Switzerland.
Over the past 10 years he has been a chief investigator on grants totalling more than $70m.
Centre Director of National Centre for Youth Substance Use Research
National Centre for Youth Substance Use Research
Faculty of Health, Medicine and Behavioural Sciences
Affiliate of Parenting and Family Support Centre
Parenting and Family Support Centre
Faculty of Health, Medicine and Behavioural Sciences
Director, NCYSUR
School of Psychology
Faculty of Health, Medicine and Behavioural Sciences
Professor
School of Psychology
Faculty of Health, Medicine and Behavioural Sciences
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Available for supervision
Jason Connor is a Professor of Clinical and Health Psychology in the Discipline of Psychiatry and Founding Director of the National Centre for Youth Substance Use Research (2008 - 2014, 2017+) at The University of Queensland.
Professor Connor is a clinical psychologist by training and a Fellow of the Australian Psychological Society (APS). He has specialist membership in the APS Health and Clinical Colleges. Jason commenced his academic career after being awarded a National Health and Medical Research Council (NH&MRC) doctoral scholarship (PhD, 2002) for research into substance use disorders.
Since moving from full-time clinical practice to academia, he has successfully combined teaching responsibilities with research.
Professor Connor has won an Australian award for excellence in university teaching.
He has published over 350 peer reviewed journal papers, books and book chapters. Professor Connor has received $25 million in research funding as Chief Investigator and currently leads $4.6 million in Catergor 1 external research grants.
Professor Connor's main research focus is substance use disorders. Research areas include substance use assessment and treatment, genetic markers of alcohol and nicotine dependence, measurement of alcohol craving, novel psychological models of problem drinking and the prevention of youth substance abuse. He is a consultant for the World Health Organisation (substance use) and member of the Federal Government’s Alcohol & Drug Centres of Excellence Strategic Reference Group, which is tasked with guiding the evidenced based policy for substance use in Australia.
Professor Connor has received awards for his research (NH&MRC Career Development Fellow; Australian Psychological Society Early Career Research Award) and service to the profession of psychology (Australian Psychological Society Health College Award of Distinction).
In addition to his academic roles, he has an appointment with Queensland Health and continues to offer clinical services.
Examples of recent publications:
Connor, J.P., Stjepanović, D., Le Foll, B., Hoch, E., Budney A., Hall, W.D. (2021) Cannabis use and cannabis use disorders. NATURE REVIEWS: DISEASE PRIMERS, 25;7(1) 16.
Ahmed, F., Boogaerts, T., Bowes, D.A., van Nuijs, A.L.N., Covaci, A., Hall, W., Connor, J.P., Thomas, K.V. (2024). Enhanced estimation of the prevalence of treated mental health disorders by wastewater-based epidemiology, NATURE MENTAL HEALTH 2, 345–347.
Connor, J.P., Stjepanović, D., Budney A., Le Foll, B., Hall, W.D. (2022) Clinical Management of Cannabis Withdrawal. ADDICTION,117(7):2075-2095.
Symons, M., Feeney, G.F.X., Gallagher, M.R., Young, R.M., Connor, J.P. (2020). Predicting alcohol dependence treatment outcomes: a prospective comparative study of clinical psychologists versus 'trained' machine learning models. ADDICTION, 115(11) 2164-2175
Connor, J.P., Hall, W.D. (2018). Thresholds for safer alcohol use might need lowering. LANCET, 391(10129), 1460-1461.
Faculty of Health, Medicine and Behavioural Sciences
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Available for supervision
Louise Conwell, MBBS(HonsI) PGCert MEd (Dundee) FRACP PhD, is a Senior Staff Specialist (Eminent) in Paediatric Endocrinology and Diabetes at the Queensland Children’s Hospital, Children’s Health Queensland. Louise’s work as a Paediatric Endocrinologist involves working in a multi-disciplinary team to care for neonates, children and adolescents with a wide spectrum of endocrinologist disorders.
Louise commenced as Head of the Children's Health Queensland Clinical Unit, School of Clinical Medicine, University of Queensland in June 2018. She is also the Acting Head of the Mayne Academy of Paediatrics, Faculty of Medicine, University of Queensland.
Louise is a graduate of the University of Queensland and trained in paediatrics at the Mater Children’s Hospital, Brisbane. She then trained in paediatric endocrinology and diabetes at the Royal Children’s Hospital in Brisbane while completing a PhD at the University of Queensland. Louise undertook a post-specialty Clinical Fellowship at the Division of Endocrinology and Metabolism, The Hospital for Sick Children, Uinversity of Toronto, Ontario, Canada.
Louise has a particular interest in Congenital Hyperinsulinism and other beta-cell disorders including Type 1 and Monogenic Diabetes. Her other clinical interest areas include Disorders of Sexual Differentiation and endocrine oncology. Louise currently works in the endocrine oncology clinic connected with the After Cancer Therapy Service at the Queensland Children's Hospital, Brisbane.
Louise's PhD was in the field of insulin resistance and cardiovascular risk in obese children and adolescents. Louise remains active in clinical research with grant attainment, particularly in the field of beta-cell disorders.
Louise is a member of national and international professional bodies. She is the current President (past Secretary) of the Australasian Paediatric Endocrine Group, serving on Council since November 2017. She also has past or present committee memberships including the Scientific Organising Committee, Clinical Fellows School Committee, Diabetes Committee, the Disorders of Sexual Differentiation Committee, Registry Committee, Research Grant Committee, Thyroid Working Group and the Cancer Survivorship Working Group).
Louise also has engagement with stakeholder groups, particularly Congenital Hyperinsulinism International. She is co-chair of the Congenital Hyperinsulinism International Collaborative Research Network - Care Guidelines and Centres of Excellence.
Louise represents the Australasian Paediatric Endocrine Group on the International Consortium of Pediatric Endocrinology (ICPE) and is co-chair of ICPE's subcommittee, the Intersociety Clinical Guidelines Committee (ICGC).
Louise has an interest in Evidence-Based Medicine, with authorship in the Cochrane Database of Systematic Reviews. She is co-Chair of the International Clinical Guidelines Committee of the International Consortium of Paediatric Endocrinology.
A further interest area includes medical ecucation, completing a Postgraduate Certificate in Medical Education (University of Dundee, Scotland) in 2017. She has facilitated and contributed to a wide range of educational activities for a variety of student, professional and community stakeholder groups in a range of contexts. Louise is a supervisor of basic and advanced paediatric trainees of the Royal Australasian College of Physicians. Other roles include Supervisor, Reader and Examiner for Postgraduate Higher Degree Research students of the University of Queensland and other academic institutions in Australia.
Faculty of Health, Medicine and Behavioural Sciences
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Available for supervision
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I am a motivated and enthusiastic Accredited Practising Dietitian and Accredited Sports Dietitian. I am interested in building sustainable foodservices worldwide, sports nutrition for recreational runners and seperate entrepreneurial ventures. I have a passion for clinical research and quality improvement projects in hospital dietetic services. Currently I want to help build sustainable foodservice systems for public/private entities that consider the future of human and planetary health. I am an ambitious individual who loves networking and who is eager to collaborate, please reach out.
My PhD research has focussed on the measurement and management of food waste in hospital foodservices through aggregate food waste audit activities and diverting food waste from landfill.
Affiliate of Minerals Industry Safety and Health Centre
Minerals Industry Safety and Health Centre
Faculty of Engineering, Architecture and Information Technology
Associate Professor
School of the Environment
Faculty of Science
Availability:
Not available for supervision
Associate Professor Margaret Cook is currently employed as the Program Leader for Occupational Health and Safety Education, within the University of Queensland, Australia. Margaret initially qualified as an Occupational Therapist and completed higher degrees in Occupational Health and Safety and Ergonomics. She is a Certified Professional Ergonomist and a Chartered Generalist OHS Professional. She holds a range of Ministerial Appointments, acting as an expert on Government Panels and Committees, and is currently Immediate Past President of the Human Factors and Ergonomics Society of Australia, and a Director of the Occupational Therapy Council of Australia.
Associate Member of Centre for Community Health and Wellbeing
Centre for Community Health and Wellbeing
Faculty of Health, Medicine and Behavioural Sciences
Affiliate of Centre for Cardiovascular Health and Research
Centre for Cardiovascular Health and Research
Faculty of Health, Medicine and Behavioural Sciences
Affiliate of Centre for Research on Exercise, Physical Activity and Health
Centre for Research on Exercise, Physical Activity and Health
Faculty of Health, Medicine and Behavioural Sciences
Professor
School of Human Movement and Nutrition Sciences
Faculty of Health, Medicine and Behavioural Sciences
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Available for supervision
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Jeff Coombes is a Professor in the School of Human Movement Studies. He completed undergraduate degrees in applied science and education and a research Masters at the University of Tasmania before gaining a PhD from the University of Florida. After completing his PhD he returned to Australia to spend two years in an academic position at the University of Tasmania before moving to the University of Queensland in 2000.
Jeff's research interests focus on determining the optimal exercise prescription for improving health. With theoretical backgrounds in biochemistry and physiology he conducts human studies and basic science projects. His findings have emphasised the importance of cardiorespiratory fitness for health benefits and many of his current projects are using high intensity interval to improve fitness and investigate outcomes. The basic science projects are identifying the mechanisms that explain the health benefits of exercise and include work in the cardiovascular and musculoskeletal systems at cellular and molecular levels. He is also a passionate advocate on the importance of fitness for health and delivers many presentations to impact on public health. His research group comprises doctors, postdoctoral fellows and PhD students and uses the extensive resources of the exercise physiology and exercise biochemistry laboratories in the School of Human Movement and Nutrition Sciences.
Current research projects of the group include;
High intensity interval training in patients with chronic kidney disease
High intensity interval training in patients with metabolic syndrome
High intensity interval training in overweight and obese children and adolescents
Cardiorespiratory fitness and outcome in patients receiving a liver transplant
Multi-disciplinary lifestyle intervention in patients with chronic kidney disease
Exercise training in patients with diabetic cardiac autonomic neuropathy
Oxidative stress and antioxidant biomarkers to predict the cardiorespiratory fitness response to exercise
Molecular mechanisms of exercise cardioprotection: relations with oxidative stress
Activation of NRF2 by nutritional supplementation in patients with type 2 diabetes
Exercise-training and skeletal muscle O-glycnacylation
Faculty of Health, Medicine and Behavioural Sciences
Affiliate of Centre for RNA in Neuroscience
Centre for RNA in Neuroscience
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Available for supervision
Helen obtained her PhD in the Department of Biochemistry and Molecular Biology at the University of Melbourne. She completed her postdoctoral fellowship at the Scripps Research Institute (San Diego) before being recruited to the Ludwig Institute for Cancer Research (Melbourne) and then the Walter and Eliza Hall Institute to establish her own laboratory. In 2003 she joined The University of Queensland as an inaugural Group Leader and Head of the Neural Migration Laboratory at the Queensland Brain Institute. Her research explores the fundamental cellular and molecular mechanisms governing the development of the neocortex.
Faculty of Health, Medicine and Behavioural Sciences
Centre Director of Queensland Aphasia Research Centre (QARC)
Queensland Aphasia Research Centre
Faculty of Health, Medicine and Behavioural Sciences
Professor
School of Health and Rehabilitation Sciences
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Available for supervision
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Professor David Copland is a Speech Pathologist conducting research in the areas of aphasia, language neuroscience, psycholinguistics, and neuroimaging of normal and disordered language. He is Director of the Queensland Aphasia Research Centre (https://shrs.uq.edu.au/qarc), Co-Director of the STARS Education Research Alliance (https://metronorth.health.qld.gov.au/stars/education-research-alliance), Co-Director of the NHMRC Centre of Research Excellence in Aphasia Rehabilitation and Recovery (https://www.latrobe.edu.au/research/centres/health/aphasia) and Deputy Chair of the Research and Postgraduate Studies Committee of the UQ School of Health and Rehabilitation Sciences.
Affiliate of Centre for Innovation in Pain and Health Research (CIPHeR)
Centre for Innovation in Pain and Health Research
Faculty of Health, Medicine and Behavioural Sciences
Senior Research Fellow
School of Health and Rehabilitation Sciences
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Available for supervision
Dr Nathalia Costa is a Senior Research Fellow at the University of Queensland's cLinical TRials cApability (ULTRA), located within the Centre for Clinical Research in Herston. Her career goal is to enhance the evidence base from clinical trials and deepen the understanding of healthcare issues through qualitative and mixed methods, with a focus on theoretically grounded, critical, reflexive and collaborative approaches. She is passionate about bringing different types of knowledge and stakeholders together to generate perspectives that create change and make research, practice and education more inclusive and nuanced. She advocates for pluralist inquiries and believes research should go beyond the dualism “quantitative/qualitative” to achieve the intersubjective understandings needed for impactful collective action. Her methodological expertise includes:
Systematic, scoping and rapid reviews
A range of qualitative methods and methodologies including but not limited to interviews, photo-elicitation, ethnography, Delphi studies, surveys, focus groups, document and policy analysis, thematic analysis, content analysis, and discourse analysis
Embedding qualitative research in feasibility trials to inform large-scale clinical trials
Conducting qualitative research to inform the development of implementation strategies
Use of systems-thinking frameworks to identify opportunities for interdisciplinary and intersectoral action to target health problems
Applying social theory to deepen understanding of healthcare and health more broadly
Participatory and collaborative research with key stakeholders (e.g., patients, clinicians, academics, policymakers)
Her publications (55+) span a diverse range of themes, including musculoskeletal conditions, pain, policy, sociology and culturally responsive care. She has also taught across a range of disciplines, including research methods, musculoskeletal physiotherapy, sociology applied to health, fundamentals of physiotherapy, fundamentals of health care, health policy, health economics and health systems finance.
Her research focuses on aspects of low back pain - from exploring ways to navigate uncertainty in low back pain care to identifying avenues to improve it within the Australian healthcare system. She is currently investigating how to optimise recruitment within the FORENSIC trial, which aims to evaluate if lumbar fusion surgery is more beneficial than continuing with best conservative care for patients with persistent severe low back pain who have already undergone non-surgical treatment.
Alongside collaborators, Nathalia has garnered grants (AUD$7.5M) and awards, including an international award for one of her PhD studies, awarded by the International Society for the Study of the Lumbar Spine – the 2021 ISSLS Prize for Lumbar Spine Research (Clinical Science).
Prior to her current appointment, she was a Post-doctoral Research Fellow at the School of Health and Rehabilitation Sciences (UQ - 2021), a Post-doctoral Research Associate at the Sydney School of Public Health (The University of Sydney, 2021-2022), and a Lecturer in Physiotherapy at the Sydney School of Health Sciences (The University of Sydney, 2023). Nathalia serves as an Associate Editor for Qualitative Health Research and the Journal of Humanities in Rehabilitation.
Australian Institute for Bioengineering and Nanotechnology
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Dr Gary Cowin is the Facility Fellow for the Queensland Node of the National Imaging Facility (NIF) as part of the National Collaborative Research Infrastructure Scheme (NCRIS), based at the Centre for Advanced Imaging, The University of Queensland.
Dr Cowin's research projects are:
Ultrahigh field magnetic resonance microimaging
Simultaneous dynamic MRI and PET imaging
Multimodal MRI/PET/CT imaging
Development of magnetic resonance techniques for non-invasive determination of liver steatosis and fibrosis
Monitoring changing fat distribution in diabetes and exercise trials
Spinal cord imaging research
Prostate research
Application of ultrahigh field MRI microimaging for tissue analysis
Molecular imaging of novel contrast agents by MRI and PET
MRI zebrafish brain atlas
Lung imaging with hyperpolarized Helium in humans and animals
Investigation of the effect of gradient non-linearity on image quality
Affiliate of The Centre for Chemistry and Drug Discovery
Centre for Chemistry and Drug Discovery
Institute for Molecular Bioscience
Affiliate of Centre for Marine Science
Centre for Marine Science
Faculty of Science
Centre Director of ARC COE for Innovations in Peptide and Protein Science
ARC COE for Innovations in Peptide and Protein Science
Institute for Molecular Bioscience
Affiliate Professor of School of Biomedical Sciences
School of Biomedical Sciences
Faculty of Health, Medicine and Behavioural Sciences
UQ Laureate Fellow - GL
Institute for Molecular Bioscience
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David Craik (AO, FRS, FAA) is in the Centre for Chemistry and Drug Discovery at the Institute for Molecular Bioscience, The University of Queensland, Australia. He discovered the cyclotide family of circular proteins and has characterized the structures of many animal toxins including conotoxins from cone snail venoms. He heads a research team of 35 researchers whose current work focuses on applications of circular proteins, drugs in plants, toxins and NMR in drug design.
He is author of over 810 scientific papers, including 14 in Nature publications (Nature/Nature Communications/Nature Neuoroscience/Nature Structural Biology/Nature Chemical Biology/Nature Chemistry/Scientific Reports/Nature Protocols, 1 in Science, 12 in PNAS, 9 in JACS, 3 in Chemical Reviews, and 16 in Angewandte Chemie. He has been elected as a Fellow of the Royal Society and a Fellow of the Australian Academy of Science, appointed as an Officer (AO) of the Order of Australia and has received numerous awards for his research, including the Ralph F. Hirschmann Award from the American Chemical Society (2011), Ramaciotti Medal for Excellence in Biomedical Research (2014), GlaxoSmithKline Award for Research Excellence (2014), the Vincent du Vigneaud Award from the American Peptide Society (2015),the FAOBMB Award for Research Excellence (2015) and the Cathay Award from the Chinese Peptide Society (2018). He received the Australian Academy of Science David Craig Medal in 2023. He is an Honorary Professor of Jinan University, Guangzhou and has an Honorary Doctorate from Kalmar University in Sweden.
Biography
David Craik obtained his PhD in organic chemistry from La Trobe University in Melbourne, Australia and undertook postdoctoral studies at Florida State and Syracuse Universities before taking up a lectureship at the Victorian College of Pharmacy in 1983. He was appointed Professor of Medicinal Chemistry and Head of School in 1988. He moved to University of Queensland in 1995 to set up a new biomolecular NMR, held an Australian Research Council Laureate Fellow (2015-2020) and is currently a NHMRC Fellow, as well as Director of the Australian Research Council Centre of Excellence in Peptide and Protein Science.
Key Discoveries
David Craik has made discoveries of new classes of proteins, generated new knowledge on their structure and function, and used this information to design and chemically re-engineer new classes of protein-based drug leads and agricultural pest control agents. In particular, his major achievements are:
the discovery of cyclotides, the largest known family of circular proteins. As well as a circular backbone, cyclotides contain a knotted arrangement of cross-linking disulfide bonds, making them remarkably stable. His discovery of these proteins was sparked in part from anecdotal reports of medicinal practices in Africa where women make a tea from the plant Oldenlandia affinis by boiling it in water and sipping it during labour to accelerate child birth. He determined the structure of the bioactive component of this medicinal tea and found that it had an unprecedented head-to-tail cyclic peptide backbone combined with a cystine knot.
the first structural and functional characterizations of prototypic circular proteins in higher organisms - Professor Craik was one of the first to recognize that other families of ribosomally synthesized cyclic peptides exist. As examples from bacteria and animals emerged, Professor Craik was at the forefront of their structural characterization, reporting the first structures of theta-defensins from animals and the threaded lasso peptide microcin J25 from bacteria, as well as new examples of cyclic peptides from plants.
the development of artificially cyclized peptide toxins as drug leads – he developed an orally active peptide that is 100 times more potent than the leading clinically used drug for neuropathic pain.
Research Training
Professor Craik has trained more than 70 PhD students. He was awarded UQ’s Research Supervision Excellence Award in 2007 on the basis of his mentoring and innovations in postgraduate training, including his “writing retreats” to mentor students and postdocs on science writing skills. He received the Institute for Molecular Bioscience Individual Leadership Award in 2019. He was awarded an honorary doctorate from Kalmar University, Sweden for his contributions to international student exchange programs, and is an Honorary Professor of Jinan University, Guangzhou.
Professional Activities
Professor Craik founded and chaired the 1st, 2nd and 3rd International Conferences on Circular Proteins (2009, 2012 and 2015) and was on the Scientific Program Committee for ISMAR 2021. He is on the Boards of six international journals, including Angewandte Chemie, ACS Chemical Biology, Chemical Biology and Drug Design, and ChemBioChem. He was on the Council of the American Peptide Society (2015-2021). He was the director two Brisbane-based biotech companies. He is on the Scientific Advisory Boards of James Cook University’s Centre for Biodiscovery and Molecular Development of Therapeutics (BMDT), the University of Wollongong’s Illawara Health and Medical Research Institute (IHMRI) and Enzytag. He conceived and supports two publicly accessible databases - Cybase on circular proteins (www.cybase.org.au), and conotoxins (www.conoserver.org).
Faculty of Health, Medicine and Behavioural Sciences
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Dr Emma Crawford is an occupational therapist and researcher whose work centres on promoting wellbeing for infants, children, families and communities. Emma's primary focus is on cross-cultural projects that link with community organisations to create social change and reduce the impacts of disadvantage by supporting health enhancing environments and activities in early life. At the centre of Emma's work is the United Nations Sustainable Development Goal 3 - ensuring healthy lives and promoting wellbeing across all ages. Currently, Emma is leading several projects:
1) The BABI Project (research): refugee and asylum seeker families' expereinces during the perinatal period (systematic review, qualitative focus group and interview research)
2) The Uni-Friends program (student delivered service and student placement) - a social-emotional helth promotion program that draws on cultural responsiveness (The Making Connecitons Framework) and community development principles in an Aboriginal and Torres Strait Islander Community Controlled School
3) LUCIE-NDC (research) - mothers' experiences of accessing Neuroprotective-Developmental Care in the first 12 months of their infants' lives
Emma has a strong interest in understanding human experiences, community-driven initiatives, and strengths-based, innovative, evidence based, complex approaches to wellbeing that consider individuals and systems She also carries out research regarding allied health student placements in culturally diverse settings including low-middle income countries and Indigenous contexts. She works as a Lecturer at the University of Queensland, Australia after having worked in a range of occupational therapy roles including with children with autism, with asylum seekers, with Indigenous Australians with chronic disease, and completing her PhD in Political Science and International Studies in 2015.