Overview
Background
Dr Camille Guillerey is a Senior Research Officer in the Cancer Immunotherapies laboratory at Mater Research. She leads a small team of researchers and students.
Dr Guillerey completed her PhD in Immunology at the Pasteur Institute of Paris, France. In 2014, she moved to Australia to study Cancer Immunonology at QIMR Berghofer Medical Research Institute. Dr Guillerey joined Kristen Radford's laboratory at Mater Research in November 2018 to establish an independent research program investigating immune responses to hematological cancers.
Dr Guillerey's research is currently focused on Natural Killer cells, a population of immune cells that recognise and kill cancer cells. She aims to identify mechanisms that may prevent Natural Killer cells from eliminating cancer cells and apply these findings to develop new treatments for childhood leukemia.
Availability
- Dr Camille Guillerey is:
- Not available for supervision
Qualifications
- Doctor of Philosophy, University of Paris
Research impacts
Dr Guillerey has authored 28 publications, and has received more than $1,7M in competitive funding from NHMRC, Cancer Australia, Cure Cancer Australia. Leukaemia Foundation and the Children Hospital Foundation. Through this research, Dr Guillerey has made integral contributions to improve knowledge on immune responses to blood cancers. She identified the immune molecules TIGIT and CD137 as promising targets in immune multiple myeloma, an incurable blood cancer. Her research contributions have been recognized with her nomination as a finalist for the 2019 Women in Technology rising star award.
Works
Search Professor Camille Guillerey’s works on UQ eSpace
2024
Journal Article
Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis
Tu, Cui, Buckle, Irina, Leal Rojas, Ingrid, Rossi, Gustavo Rodrigues, Sester, David P, Moore, Andrew S, Radford, Kristen, Guillerey, Camille and Souza‐Fonseca‐Guimaraes, Fernando (2024). Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis. Clinical & Translational Immunology, 13 (3) e1501, e1501. doi: 10.1002/cti2.1501
2023
Journal Article
Characterization of human engraftment and hemophagocytic lymphohistiocytosis in NSG-SGM3 neonate mice engrafted with purified CD34+ hematopoietic stem cells
Liam, O'Brien, Carina, Walpole, Ingrid, Leal-Rojas, Svetlana, Shatunova, Andrew, Moore, Winkler, Ingrid G, Camille, Guillerey and Radford, Kristen J (2023). Characterization of human engraftment and hemophagocytic lymphohistiocytosis in NSG-SGM3 neonate mice engrafted with purified CD34+ hematopoietic stem cells. Experimental Hematology, 130 104134, 104134. doi: 10.1016/j.exphem.2023.11.008
2023
Journal Article
TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation
Pichler, Andrea C., Carrié, Nadège, Cuisinier, Marine, Ghazali, Samira, Voisin, Alison, Axisa, Pierre-Paul, Tosolini, Marie, Mazzotti, Céline, Golec, Dominic P., Maheo, Sabrina, do Souto, Laura, Ekren, Rüçhan, Blanquart, Eve, Lemaitre, Lea, Feliu, Virginie, Joubert, Marie-Véronique, Cannons, Jennifer L., Guillerey, Camille, Avet-Loiseau, Hervé, Watts, Tania H., Salomon, Benoit L., Joffre, Olivier, Grinberg-Bleyer, Yenkel, Schwarzberg, Pamela L., Lucca, Liliana E. and Martinet, Ludovic (2023). TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation. Immunity, 56 (7), 1631-1648.e10. doi: 10.1016/j.immuni.2023.06.007
2023
Journal Article
High dimensional analysis reveals distinct NK cell subsets but conserved response to stimulation in umbilical cord blood and adult peripheral blood
Buckle, Irina, Johnson, Anthony, Rojas, Ingrid Leal, Weinert, Vicky, Sester, David P., Radford, Kristen and Guillerey, Camille (2023). High dimensional analysis reveals distinct NK cell subsets but conserved response to stimulation in umbilical cord blood and adult peripheral blood. European Journal of Immunology, 53 (6) 2250118, 1-13. doi: 10.1002/eji.202250118
2021
Journal Article
Inhibitory receptors and immune checkpoints regulating natural killer cell responses to cancer
Buckle, Irina and Guillerey, Camille (2021). Inhibitory receptors and immune checkpoints regulating natural killer cell responses to cancer. Cancers, 13 (17) 4263, 4263. doi: 10.3390/cancers13174263
2020
Journal Article
Eomes-dependent loss of the co-activating receptor CD226 restrains CD8+ T cell anti-tumor functions and limits the efficacy of cancer immunotherapy
Weulersse, Marianne, Asrir, Assia, Pichler, Andrea C., Lemaitre, Lea, Braun, Matthias, Carrié, Nadège, Joubert, Marie-Véronique, Le Moine, Marie, Do Souto, Laura, Gaud, Guillaume, Das, Indrajit, Brauns, Elisa, Scarlata, Clara M., Morandi, Elena, Sundarrajan, Ashmitha, Cuisinier, Marine, Buisson, Laure, Maheo, Sabrina, Kassem, Sahar, Agesta, Arantxa, Pérès, Michaël, Verhoeyen, Els, Martinez, Alejandra, Mazieres, Julien, Dupré, Loïc, Gossye, Thomas, Pancaldi, Vera, Guillerey, Camille, Ayyoub, Maha ... Martinet, Ludovic (2020). Eomes-dependent loss of the co-activating receptor CD226 restrains CD8+ T cell anti-tumor functions and limits the efficacy of cancer immunotherapy. Immunity, 53 (4), 824-839.e10. doi: 10.1016/j.immuni.2020.09.006
2020
Journal Article
Systemic administration of IL‐33 induces a population of circulating KLRG1 hi type 2 innate lymphoid cells and inhibits type 1 innate immunity against multiple myeloma
Guillerey, Camille, Stannard, Kimberley, Chen, Jason, Krumeich, Sophie, Miles, Kim, Nakamura, Kyohei, Smith, Jessica, Yu, Yuan, Ng, Susanna, Harjunpää, Heidi, Teng, Michele W. L., Engwerda, Christian, Belz, Gabrielle T. and Smyth, Mark J. (2020). Systemic administration of IL‐33 induces a population of circulating KLRG1 hi type 2 innate lymphoid cells and inhibits type 1 innate immunity against multiple myeloma. Immunology and Cell Biology, 99 (1) imcb.12390, 65-83. doi: 10.1111/imcb.12390
2020
Book Chapter
NK cells in the tumor microenvironment
Guillerey, Camille (2020). NK cells in the tumor microenvironment. Tumor microenvironment: hematopoietic cells – part B. (pp. 69-90) edited by Alexander Birbrair. Cham, Switzerland: Springer . doi: 10.1007/978-3-030-49270-0_4
2019
Journal Article
TIGIT as an emerging immune checkpoint
Harjunpaeae, H. and Guillerey, C. (2019). TIGIT as an emerging immune checkpoint. Clinical and Experimental Immunology, 200 (2) cei.13407, 108-119. doi: 10.1111/cei.13407
2019
Journal Article
Chemotherapy followed by anti-CD137 mAb immunotherapy improves disease control in a mouse myeloma model
Guillerey, Camille, Nakamura, Kyohei, Pichler, Andrea C., Barkauskas, Deborah, Krumeich, Sophie, Stannard, Kimberley, Miles, Kim, Harjunpää, Heidi, Yu, Yuan, Casey, Mika, Doban, Alina I., Lazar, Mircea, Hartel, Gunter, Smith, David, Vuckovic, Slavica, Teng, Michele W.L., Bergsagel, P. Leif, Chesi, Marta, Hill, Geoffrey R., Martinet, Ludovic and Smyth, Mark J. (2019). Chemotherapy followed by anti-CD137 mAb immunotherapy improves disease control in a mouse myeloma model. JCI Insight, 4 (14) :e125932. doi: 10.1172/jci.insight.125932
2019
Journal Article
Can Dendritic Cell vaccination prevent leukemia relapse?
O’Brien, Liam J., Guillerey, Camille and Radford, Kristen J. (2019). Can Dendritic Cell vaccination prevent leukemia relapse?. Cancers, 11 (6) 875, 875. doi: 10.3390/cancers11060875
2019
Journal Article
Human peripheral blood DNAM-1neg NK cells are a terminally differentiated subset with limited effector functions
Stannard, Kimberley A., Lemoine, Sébastien, Waterhouse, Nigel J., Vari, Frank, Chatenoud, Lucienne, Gandhi, Maher K., Martinet, Ludovic, Smyth, Mark J. and Guillerey, Camille (2019). Human peripheral blood DNAM-1neg NK cells are a terminally differentiated subset with limited effector functions. Blood Advances, 3 (11), 1681-1694. doi: 10.1182/bloodadvances.2018030676
2018
Journal Article
Roles of cytotoxic and helper innate lymphoid cells in cancer
Guillerey, Camille (2018). Roles of cytotoxic and helper innate lymphoid cells in cancer. Mammalian Genome, 29 (11-12), 777-789. doi: 10.1007/s00335-018-9781-4
2018
Journal Article
Myeloma escape after stem cell transplantation is a consequence of t-cell exhaustion and is prevented by tigit blockade
Minnie, Simone A., Kuns, Rachel D., Gartlan, Kate H., Zhang, Ping, Wilkinson, Andrew N., Samson, Luke, Guillerey, Camille, Engwerda, Christian, MacDonald, Kelli P. A., Smyth, Mark J., Markey, Kate A., Vuckovic, Slavica and Hill, Geoffrey R. (2018). Myeloma escape after stem cell transplantation is a consequence of t-cell exhaustion and is prevented by tigit blockade. Blood, 132 (16), 1675-1688. doi: 10.1182/blood-2018-01-825240
2018
Journal Article
Bone marrow transplantation generates T cell–dependent control of myeloma in mice
Vuckovic, Slavica, Minnie, Simone A., Smith, David, Gartlan, Kate H., Watkins, Thomas S., Markey, Kate A., Mukhopadhyay, Pamela, Guillerey, Camille, Kuns, Rachel D., Locke, Kelly R., Pritchard, Antonia L., Johansson, Peter A., Varelias, Antiopi, Zhang, Ping, Huntington, Nicholas D., Waddell, Nicola, Chesi, Marta, Miles, John J., Smyth, Mark J. and Hill, Geoffrey R. (2018). Bone marrow transplantation generates T cell–dependent control of myeloma in mice. Journal of Clinical Investigation, 129 (1) CI98888, 106-121. doi: 10.1172/jci98888
2018
Journal Article
TIGIT immune checkpoint blockade restores CD8 T cell immunity against multiple myeloma
Guillerey, Camille, Harjunpää, Heidi, Carrié, Nadège, Kassem, Sahar, Teo, Tricia, Miles, Kim, Krumeich, Sophie, Weulersse, Marianne, Cuisinier, Marine, Stannard, Kimberley, Yu, Yuan, Minnie, Simone A., Hill, Geoffrey R., Dougall, William C., Avet-Loiseau, Hervé, Teng, Michele W. L., Nakamura, Kyohei, Martinet, Ludovic and Smyth, Mark J. (2018). TIGIT immune checkpoint blockade restores CD8 T cell immunity against multiple myeloma. Blood, 132 (16), blood-2018. doi: 10.1182/blood-2018-01-825265
2018
Journal Article
Mitochondrial reactive oxygen species regulate the induction of CD8+ T cells by plasmacytoid dendritic cells
Oberkampf, Marine, Guillerey, Camille, Mouriès, Juliette, Rosenbaum, Pierre, Fayolle, Catherine, Bobard, Alexandre, Savina, Ariel, Ogier-Denis, Eric, Enninga, Jost, Amigorena, Sebastian, Leclerc, Claude and Dadaglio, Gilles (2018). Mitochondrial reactive oxygen species regulate the induction of CD8+ T cells by plasmacytoid dendritic cells. Nature Communications, 9 (1) 2241, 2241. doi: 10.1038/s41467-018-04686-8
2018
Journal Article
Tumor-derived TGFb alters the ability of plasmacytoid dendritic cells to respond to innate immune signaling
Terra, Mariana, Oberkampf, Marine, Fayolle, Catherine, Rosenbaum, Pierre, Guillerey, Camille, Dadaglio, Gilles and Leclerc, Claude (2018). Tumor-derived TGFb alters the ability of plasmacytoid dendritic cells to respond to innate immune signaling. Cancer Research, 78 (11), 3014-3026. doi: 10.1158/0008-5472.CAN-17-2719
2018
Conference Publication
Syngeneic stem cell transplantation generates antigen-specific T cells that maintain myeloma-immune equilibrium
Minnie, Simone, Vuckovic, Slavica, Smith, David, Gartlan, Kate H., Watkins, Thomas S., Kuns, Rachel D., Guillerey, Camille, Chesi, Marta, Markey, Kate A., Miles, John J., Smyth, Mark J. and Hill, Geoffrey R. (2018). Syngeneic stem cell transplantation generates antigen-specific T cells that maintain myeloma-immune equilibrium. Immunology Meeting, Austin, TX, United States, 4-8 May, 2018. Rockville, MD, United States: American Association of Immunologists.
2018
Conference Publication
Syngeneic stem cell transplantation generates antigen-specific T cells that maintain myeloma-immune equilibrium
Minnie, Simone, Vuckovic, Slavica, Smith, David, Gartlan, Kate H., Watkins, Thomas S., Kuns, Rachel D., Guillerey, Camille, Chesi, Marta, Markey, Kate A., Miles, John J., Smyth, Mark J. and Hill, Geoffrey R. (2018). Syngeneic stem cell transplantation generates antigen-specific T cells that maintain myeloma-immune equilibrium. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.55.19
Funding
Past funding
Supervision
Availability
- Dr Camille Guillerey is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
Immune regulation through bi-directional interactions between subsets of Natural Killer cells and Dendritic cells.
Associate Advisor
Other advisors: Professor Andrew Barbour, Dr Arutha Kulasinghe, Dr Gustavo Rodrigues Rossi, Associate Professor Fernando Guimaraes
Completed supervision
-
2022
Doctor Philosophy
Establishing Humanized Mouse Models to Evaluate Immunotherapy
Associate Advisor
Other advisors: Dr Ingrid Winkler, Honorary Professor Kristen Radford
-
2019
Doctor Philosophy
Tumor Immunity and Autoimmunity Following Cancer Immunotherapy
Associate Advisor
Media
Enquiries
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