Overview
Background
Dr Camille Guillerey is a Senior Research Officer in the Cancer Immunotherapies laboratory at Mater Research. She leads a small team of researchers and students.
Dr Guillerey completed her PhD in Immunology at the Pasteur Institute of Paris, France. In 2014, she moved to Australia to study Cancer Immunonology at QIMR Berghofer Medical Research Institute. Dr Guillerey joined Kristen Radford's laboratory at Mater Research in November 2018 to establish an independent research program investigating immune responses to hematological cancers.
Dr Guillerey's research is currently focused on Natural Killer cells, a population of immune cells that recognise and kill cancer cells. She aims to identify mechanisms that may prevent Natural Killer cells from eliminating cancer cells and apply these findings to develop new treatments for childhood leukemia.
Availability
- Dr Camille Guillerey is:
- Not available for supervision
Qualifications
- Doctor of Philosophy, University of Paris
Research impacts
Dr Guillerey has authored 28 publications, and has received more than $1,7M in competitive funding from NHMRC, Cancer Australia, Cure Cancer Australia. Leukaemia Foundation and the Children Hospital Foundation. Through this research, Dr Guillerey has made integral contributions to improve knowledge on immune responses to blood cancers. She identified the immune molecules TIGIT and CD137 as promising targets in immune multiple myeloma, an incurable blood cancer. Her research contributions have been recognized with her nomination as a finalist for the 2019 Women in Technology rising star award.
Works
Search Professor Camille Guillerey’s works on UQ eSpace
2018
Journal Article
Deficiency of host CD96 and PD-1 or TIGIT enhances tumor immunity without significantly compromising immune homeostasis
Harjunpää, Heidi, Blake, Stephen J., Ahern, Elizabeth, Allen, Stacey, Liu, Jing, Yan, Juming, Lutzky, Viviana, Takeda, Kazuyoshi, Aguilera, Amy Roman, Guillerey, Camille, Mittal, Deepak, Li, Xian Yang, Dougall, William C., Smyth, Mark J. and Teng, Michele W. L. (2018). Deficiency of host CD96 and PD-1 or TIGIT enhances tumor immunity without significantly compromising immune homeostasis. OncoImmunology, 7 (7) e1445949, e1445949. doi: 10.1080/2162402X.2018.1445949
2018
Journal Article
Dysregulated IL-18 Is a key driver of immunosuppression and a possible therapeutic target in the multiple myeloma microenvironment
Nakamura, Kyohei, Kassem, Sahar, Cleynen, Alice, Chrétien, Marie-Lorraine, Guillerey, Camille, Putz, Eva Maria, Bald, Tobias, Förster, Irmgard, Vuckovic, Slavica, Hill, Geoffrey R, Masters, Seth L, Chesi, Marta, Bergsagel, P Leif, Avet-Loiseau, Hervé, Martinet, Ludovic and Smyth, Mark J. (2018). Dysregulated IL-18 Is a key driver of immunosuppression and a possible therapeutic target in the multiple myeloma microenvironment. Cancer Cell, 33 (4), 634-648. doi: 10.1016/j.ccell.2018.02.007
2018
Journal Article
Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection
Ng, Susanna S., Souza-Fonseca-Guimaraes, Fernando, Rivera, Fabian de Labastida, Amante, Fiona H., Kumar, Rajiv, Gao, Yulong, Sheel, Meru, Beattie, Lynette, de Oca, Marcela Montes, Guillerey, Camille, Edwards, Chelsea L., Faleiro, Rebecca J., Frame, Teija, Bunn, Patrick T., Vivier, Eric, Godfrey, Dale I., Pellicci, Daniel G., Lopez, J. Alejandro, Andrews, Katherine T., Huntington, Nicholas D., Smyth, Mark J., McCarthy, James and Engwerda, Christian R. (2018). Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection. Clinical and Translational Immunology, 7 (1) e1003, e1003. doi: 10.1002/cti2.1003
2017
Journal Article
Cytokine-driven role of Srebps in killer cell metabolism
Guillerey, Camille and Smyth, Mark J. (2017). Cytokine-driven role of Srebps in killer cell metabolism. Nature Immunology, 18 (11), 1183-1184. doi: 10.1038/ni.3855
2017
Journal Article
Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis
Putz, Eva M., Guillerey, Camille, Kos, Kevin, Stannard, Kimberley, Miles, Kim, Delconte, Rebecca B, Takeda, Kazuyoshi, Nicholson, Sandra E., Huntington, Nicholas D. and Smyth, Mark J. (2017). Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis. OncoImmunology, 6 (2) e1267892, e1267892. doi: 10.1080/2162402X.2016.1267892
2016
Journal Article
Targeting natural killer cells in cancer immunotherapy
Guillerey, Camille, Huntington, Nicholas D. and Smyth, Mark J. (2016). Targeting natural killer cells in cancer immunotherapy. Nature Immunology, 17 (9), 1025-1036. doi: 10.1038/ni.3518
2016
Conference Publication
Therapeutic potential anti-CD137 mAbs in multiple myeloma
Guillerey, C., de Andrade, L. F., Miles, K., Vuckovic, S., Chesi, M., Bergsagel, L. P., Geoffrey, R. H., Martinet, L. and Smyth, M. J. (2016). Therapeutic potential anti-CD137 mAbs in multiple myeloma. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August, 2016. Weinheim, Germany: Wiley - V C H Verlag GmbH.
2016
Journal Article
Immune responses in multiple myeloma: role of the natural immune surveillance and potential of immunotherapies
Guillerey, Camille, Nakamura, Kyohei, Vuckovic, Slavica, Hill, Geoffrey R. and Smyth, Mark J. (2016). Immune responses in multiple myeloma: role of the natural immune surveillance and potential of immunotherapies. Cellular and Molecular Life Sciences, 73 (8), 1569-1589. doi: 10.1007/s00018-016-2135-z
2016
Book Chapter
NK cells and cancer immunoediting
Guillerey, Camille and Smyth, Mark J. (2016). NK cells and cancer immunoediting. Natural killer cells. (pp. 115-145) edited by Eric Vivier, James Di Santo and Alessandro Moretta. [Cham], Switzerland: Springer. doi: 10.1007/82_2015_446
2015
Journal Article
Erratum: Immunosurveillance and therapy of multiple myeloma are CD226 dependent
Guillerey, Camille, de Andrade, Lucas Ferrari, Vuckovic, Slavica, Miles, Kim, Ngiow, Shin Foong, Yong, Michelle C. R., Teng, Michele W. L., Colonna, Marco, Ritchie, David S., Chesi, Marta, Bergsagel, P. Leif, Hill, Geoffrey R., Smyth, Mark J. and Martinet, Ludovic (2015). Erratum: Immunosurveillance and therapy of multiple myeloma are CD226 dependent. Journal of Clinical Investigation, 125 (7), 2904-2904. doi: 10.1172/JCI82646
2015
Journal Article
Immunosurveillance and therapy of multiple myeloma are CD226 dependent
Guillerey, Camille, de Andrade, Lucas Ferrari, Vuckovic, Slavica, Miles, Kim, Ngiow, Shin Foong, Yong, Michelle C. R., Teng, Michele W. L., Colonna, Marco, Ritchie, David S., Chesi, Martha, Bergsagel, P. Leif, Hill, Geoffrey R., Smyth, Mark J. and Martinet, Ludovic (2015). Immunosurveillance and therapy of multiple myeloma are CD226 dependent. Journal of Clinical Investigation, 125 (5), 2077-2089. doi: 10.1172/JCI77181
2015
Journal Article
DNAM-1 expression marks an alternative program of NK cell maturation
Martinet, Ludovic, FerrariDeAndrade, Lucas, Guillerey, Camille, Lee, Jason S, Liu, Jing, Souza-Fonseca-Guimaraes, Fernando, Hutchinson, Dana S, Kolesnik, Tatiana B, Nicholson, Sandra E, Huntington, Nicholas D and Smyth, Mark J (2015). DNAM-1 expression marks an alternative program of NK cell maturation. Cell Reports, 11 (1), 85-97. doi: 10.1016/j.celrep.2015.03.006
2015
Journal Article
Toll-like receptor 3 regulates NK cell responses to cytokines and controls experimental metastasis
Guillerey, Camille, Chow, Melvyn T., Miles, Kim, Olver, Stuart, Sceneay, Jaclyn, Takeda, Kazuyoshi, Möller, Andreas and Smyth, Mark J. (2015). Toll-like receptor 3 regulates NK cell responses to cytokines and controls experimental metastasis. Oncoimmunology, 4 (9), 1-11. doi: 10.1080/2162402X.2015.1027468
2012
Journal Article
Pivotal role of plasmacytoid dendritic cells in inflammation and NK-cell responses after TLR9 triggering in mice
Guillerey, Camille, Mouries̀, Juliette, Polo, Giulia, Doyen, Noelle, Law, Helen K. W., Chan, Susan, Kastner, Philippe, Leclerc, Claude and Dadaglio, Gilles (2012). Pivotal role of plasmacytoid dendritic cells in inflammation and NK-cell responses after TLR9 triggering in mice. Blood, 120 (1), 90-99. doi: 10.1182/blood-2012-02-410936
2009
Journal Article
FoxO3 Regulates Neural Stem Cell Homeostasis
Renault, Valérie M., Rafalski, Victoria A., Morgan, Alex A., Salih, Dervis A.M., Brett, Jamie O., Webb, Ashley E., Villeda, Saul A., Thekkat, Pramod U., Guillerey, Camille, Denko, Nicholas C., Palmer, Theo D., Butte, Atul J. and Brunet, Anne (2009). FoxO3 Regulates Neural Stem Cell Homeostasis. Cell Stem Cell, 5 (5), 527-539. doi: 10.1016/j.stem.2009.09.014
Funding
Past funding
Supervision
Availability
- Dr Camille Guillerey is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
Immune regulation through bi-directional interactions between subsets of Natural Killer cells and Dendritic cells.
Associate Advisor
Other advisors: Professor Andrew Barbour, Dr Arutha Kulasinghe, Dr Gustavo Rodrigues Rossi, Associate Professor Fernando Guimaraes
Completed supervision
-
2022
Doctor Philosophy
Establishing Humanized Mouse Models to Evaluate Immunotherapy
Associate Advisor
Other advisors: Dr Ingrid Winkler, Honorary Professor Kristen Radford
-
2019
Doctor Philosophy
Tumor Immunity and Autoimmunity Following Cancer Immunotherapy
Associate Advisor
Media
Enquiries
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