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Emeritus Professor Maree Smith AC FTSE FAHMS is a full-time researcher and Director, CIPDD, School of Biomedical Sciences, Faculty of Medicine, The University of Queensland.

In the 12 years prior to her current appointment, Professor Smith led a high-performing team in building the CIPDD and its commercial interface TetraQ, recognized as a unique, GLP-accredited drug development Centre in Australia. Professor Smith has considerable expertise in biomedical discovery/translation with specialist expertise in the novel pain therapeutics discovery/translation field encompassing a portfolio of 16 rodent pain models that mimic individual human pain conditions. This portfolio of models conducted in a purpose-built facility operated in accordance with the requirements of our Quality Management System, making the CIPDD unique in Australia and rare internationally.

In the 15 years prior to establishing the CIPDD, Professor Maree Smith was a full-time academic in the School of Pharmacy. In brief, she joined the School of Pharmacy as a Lecturer in 1989 and was successively promoted through the academic ranks to Professor in 2004. Prior to that she undertook a PhD and early postdoctoral training in clinical pharmacology with specialist expertise in bioanalytical method development, bioanalysis of human plasma samples, drug metabolism and clinical pharmacokinetics. Her second postdoc was in the field of pain management and pain pharmacology.

In the years, 1990-2005, Maree Smith taught in the Drug Discovery stream of the 2nd, 3rd & 4th years of the undergraduate Pharmacy program and she was instrumental in developing innovative courses for the final year of the undergraduate Pharmacy curriculum. She was also instrumental in the development of a course for the M Biotech program at UQ entitled “Quality Systems in Biotechnology” which continues to this day and is a compulsory course in the Program. Maree has successfully advised/co-advised to completion 33 PhD students, 2 Research Masters students and ~50 Honours students. She also served for 14 years as an external evaluator for the TGA.

Maree's Current Research Interests are as follows:

1. Subtle differences in the pathobiology of individual chronic pain conditions

2. Improving preclinical to clinical translation in novel analgesics development

3. Preclinical drug development of novel pain therapeutics

4. Preclinical drug development

Awards

2021 UQ Fellowship

2019 Companion of the Order of Australia (AC) in the Queen's Birthday Honours List

2018 Honorary Bragg Membership (The Royal Institution of Australia)

2016 Bowl of Hygeia Award (Pharmaceutical Society of Australia)

2016 Clunies Ross Knowledge Commercialisation Award (ATSE)

2015 Honoured to be included in inaugural list of Australia's top Innovators; viz Knowledge Nation 100

2015 Inaugural Inductee into the Life Sciences Queensland (LSQ) Hall of Fame

2015 Johnson and Johnson Innovaton AusBiotech Industry Excellen Award - Outstanding Leader category.

2015 Elected Fellow, Australian Academy of Health and Medical Sciences (AAHMS)

2015 Australian Pain Society Distinguished Member Award - For services to the promotion, treatment and science of pain management and lifelong contribution to the Australian Pain Society

2013 UQ Top 5 Inventor - Award by Thomson Reuters and UQ at inaugural Awards

2013 UQ Top 5 Innovator - Award by UniQuest Pty Ltd and UQ at inaugural Awards

2012 Queensland Life Sciences Industry Excellence Award jointly with Dr Jim Aylward

2011 Elected Fellow, Australian Academy of Technological Sciences (ATSE)

2009 Honorary Fellowship, Faculty of Pain Medicine, ANZCA (Australian and New Zealand College of Anaesthetists).

2008 WiT (Women in Technology): Biotech Outstanding Achievement Award

2002 Meritorious Mention for Sustained Excellence in Research Higher Degree Supervision

2001 Meritorious Mention for Sustained Excellence in Research Higher Degree Supervision

Professor Heather Smyth is a flavour chemist and sensory scientist who has been working with premium food and beverage products for more than twenty years. With a background in wine flavour chemistry, her expertise is in understanding consumer enjoyment of foods and beverages in terms of both sensory properties and composition.

Smyth has a special interest in describing and articulating food quality, understanding regional flavours of locally grown Australian produce, and modelling food flavour and textural properties using instrumental measurements. Smyth also specialises in researching how human physiology and psychology can impact sensory perception and therefore food choice.

I began my scientific career with a Bachelor of Science in Biochemistry and Chemistry, followed by a Bachelor of Science with First Class Honours in Chemistry from Massey University, New Zealand. My honours project focused on developing hydrogels for controlled peptide release in the gut. I then pursued a PhD at Massey University, working on synthetic anti-cancer drugs based on cyclodextrins.

After completing my PhD, I worked as a Research Officer at the New Zealand Veterinary Pathology Epicentre, refining my diagnostic research skills. I continued my career as a Postdoctoral Fellow at Kansas State University, contributing to the detection and surveillance of zoonotic diseases in the swine industry.

Currently, at the University of Queensland, I integrate my expertise in synthetic peptides with vaccine development. My research bridges medical and agricultural biotechnology, focusing on innovative adjuvants and vaccines that span medicinal chemistry, nanotechnology, and immunology, aiming to enhance both health outcomes and agricultural practices.

Dr Phong Thai is an ARC Mid-Career Industry Fellow. Phong joined Queensland Alliance for Environmental Health Sciences (QAEHS) in 2018 after his Vice Chancellor Senior Research Fellowship at the International Laboratory of Air Quality and Health at Queensland University of Technology. His research focus at QAEHS involves the expansion of wastewater-based epidemiological approach to estimate community consumption and exposure to a range of licit and illicit substances including tobacco and alcohol, pharmaceuticals and as well as the monitoring of community infection to Covid-19 during the last pandemic. He is a member of the team who manage the National Wastewater Drug Monitoring Program.

Phong is also working on projects monitoring occurence, fate and transport of environmental pollutants in different matrices. He has lso far ed or contributed to several exciting projects totalling > A$ 15 millions.

Professor Kevin Thomas is Director of the Queensland Alliance for Environmental Health Sciences (QAEHS). Kevin is an environmental health scientist with a particular interest in understanding the environmental exposures associated with contaminants of emerging concern (CECs) with the goal of protecting environmental and human health. Kevin also leads the Minderoo Centre- Plastics and Human Health at UQ and is Deputy-Director of the Australian Research Council Industrial Transformation Training Centre for Hyphenated Analytical Separation Technologies (HyTech).

His current research is focused on understanding human exposure to plastics pollution and developing mass spectrometric analytical methods for characterizing plastics and other CECs, assessing community-wide health status through analysing wastewater (wastewater-based epidemiology) and establishing alternative approaches to exposure monitoring, for example explanted silicone prostheses and wristbands.

Author of over 300 peer-reviewed papers and Associate Editor for the journal Science of the Total Environment, Kevin is a strong collaborative researcher having founded the international SCORE network on sewer biomarker analysis for community health assessment (see www.score-network.eu) and together with colleagues has recently launched InSpectra- A platform for identifying emerging chemical threats.

Dr Ben Tscharke is an analytical chemist with a keen interest in quantifying analytes in environmental samples. Ben is currently a Senior Research Fellow at the University of Queensland research institute, Queensland Alliance for Environmental Health Sciences (QAEHS), joining in February 2017 after graduating his PhD from the University of South Australia the previous year. His key focus at QAEHS involves the wastewater based epidemiological approach to determine community consumption and exposure to a range of illicit drugs, pharmaceuticals and personal care products. He leads the Australian Criminal Intelligence Commission's National Wastewater Drug Monitoring program at UQ, which collaborates with the University of South Australia (https://www.acic.gov.au/publications/intelligence-products/national-wastewater-drug-monitoring-program-report).

Karnaker's research interests are natural products, peptide-based drug discovery and development, formulation chemistry and non-viral gene delivery system. Karnaker co-inventor and developed a novel, bioresponsive disulphide-linker technology, which has been used for non-viral vectors, peptide-therapeutics for pain and cancer treatment. Karnaker is also keen interest for topical, mucosal drug delivery using a range of dendrimer, nano and microbubbles, lipid and polymer-based nanoparticle systems in conjugation with both biological and physical stimuli-responsiveness.

Karnaker received a PhD in Pharmaceutical Chemistry from The University Queensland under the supervision of Dr Harendra Parekh and Dr Defang Ouyang. Prior to PhD, he completed a Master degree in Pharmaceutical Analysis and Quality assurance (India). Also worked as analytical research and development chemist for one year in a Pharma company. Since 2016, he his working with Dr Parekh team on a range of Industry-funded research projects and his role involves from ideation, research plan, execution, product delivery to industry partners on major platforms such as peptide-based therapeutics, gene therapy and sol-gel technology.

Associate Professor Ryan Turner is the Director of the Reef Catchments Science Partnership at the University of Queensland (a partnership with the Department of the Environment, Tourism, Science and Innovation). Ryan was previously the Department's Principal Scientist for Water Quality and Investigations and held an Adjunct Associate Professor role at Queensland University of Technology in the Managing for Resilient Landscapes, Institute for Future Environments. For 14 years, Ryan managed multimillion-dollar water quality monitoring programs assessing the impacts of sediments, nutrients, and pesticides in numerous catchments along the Queensland coast discharging to the Great Barrier Reef and Moreton Bay. Ryan has been on several steering committees and technical advisory panels, such as the Great Barrier Reef Foundations Technical Advisory Panel. He has published extensively (>80 papers and reports) and led several Queensland Government – Academic collaborative research projects. Ryan previously supervised analytical chemistry and microbiology laboratories in the private and public sectors. Ryan has developed numerous methodologies and standard operating procedures for analytical and monitoring techniques (water quality, sediments and soils). Ryan’s passion for the future of water security is what keeps him striving forward.

Educated at the University of Copenhagen, Denmark, and the Australian National University, Canberra. Career at the Université de Lausanne, Switzerland, and the Universität Marburg, Germany. Professor and Chair of Organic Chemistry and Head of the Organic Chemistry Section, The University of Queensland from 1985. Emeritus professor from 2008. Chair of the National Committee for Chemistry of the Australian Academy of Science 2009-2014. Editor-in-Chief, Australian Journal of Chemistry 2008-15. Editor, Journal of Analytical and Applied Pyrolysis (Elsevier, IF 3.65) 2016-. Visiting Professor Université de Pau, France, 2011-19; Visiting Professor University of Kuwait 2014-18; Visiting Professor / Special Appointed Professor Hiroshima University 2014-18. Fellow of the Australian Academy of Science. Centenary Medal of the Australian Commonwealth 2003 for research in organic and physical chemistry. David Craig Medal of the Academy of Science 2014 for research in chemistry. JSPS Fellowship (Japan) 2014. Honorary doctorate, University of Pau, France, 2014. A.J. Birch Medal of the Royal Australian Chemical Institute (RACI) for ecellence in research in organic chemistry, 2014. Leighton Medal of the RACI 2018.

Research on Unusual Molecules and Reactive Intermediates: Synthesis and Reaction Mechanism. Heterocyclic chemistry. Pyrolysis reactions. Photochemistry

Research in the Wentrup group is concerned with the discovery of novel types of molecules with new and unusual bonding patterns. Such molecules are mostly highly reactive, and special methods are required both for their generation and for their detection. The group has developed these methods over many years and acquired world-class equipment for these purposes, including flash vacuum thermolysis apparatus, cryostats for matrix isolation of reaction products at cryogenic temperatures (down to 7 K), matrix and solution photochemistry equipment, infrared, UV and mass spectrometers, as well as modern computational facilities.

This research has resulted in the synthesis and characterization of many novel compounds, including extended cumulenes of the types RN=C=C=C=X, which themselves are used in the synthesis of many novel types of molecules, some of them of potential pharmaceutical interest (quinolone antibiotics; diazepines).

The research group has a world reputation in the field of carbene and nitrene chemistry, involving reactive intermediates with sextet carbon or nitrogen. These species are also very useful in synthesis, for example in the preparation of diazepines and diazepinones, a family of pharmaceutically interesting compounds. Numerous mechanistic studies and synthetic applications of ketenes have been carried out in our group.

Active collaborations are ongoing with scientists in Australia (UQ and CSIRO), China (Suzhou), France (Pau), Germany (Oldenburg), Japan (Hiroshima), Spain (Donostia - San Sebastian), and Portugal (Coimbra).