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Emeritus Professor Curt Wentrup
Emeritus Professor

Curt Wentrup

Email: 
Phone: 
+61 7 336 53817

Overview

Background

Educated at the University of Copenhagen, Denmark, and the Australian National University, Canberra. Career at the Université de Lausanne, Switzerland, and the Universität Marburg, Germany. Professor and Chair of Organic Chemistry and Head of the Organic Chemistry Section, The University of Queensland from 1985. Emeritus professor from 2008. Chair of the National Committee for Chemistry of the Australian Academy of Science 2009-2014. Editor-in-Chief, Australian Journal of Chemistry 2008-15. Editor, Journal of Analytical and Applied Pyrolysis (Elsevier, IF 3.65) 2016-. Visiting Professor Université de Pau, France, 2011-19; Visiting Professor University of Kuwait 2014-18; Visiting Professor / Special Appointed Professor Hiroshima University 2014-18. Fellow of the Australian Academy of Science. Centenary Medal of the Australian Commonwealth 2003 for research in organic and physical chemistry. David Craig Medal of the Academy of Science 2014 for research in chemistry. JSPS Fellowship (Japan) 2014. Honorary doctorate, University of Pau, France, 2014. A.J. Birch Medal of the Royal Australian Chemical Institute (RACI) for ecellence in research in organic chemistry, 2014. Leighton Medal of the RACI 2018.

Research on Unusual Molecules and Reactive Intermediates: Synthesis and Reaction Mechanism. Heterocyclic chemistry. Pyrolysis reactions. Photochemistry

Research in the Wentrup group is concerned with the discovery of novel types of molecules with new and unusual bonding patterns. Such molecules are mostly highly reactive, and special methods are required both for their generation and for their detection. The group has developed these methods over many years and acquired world-class equipment for these purposes, including flash vacuum thermolysis apparatus, cryostats for matrix isolation of reaction products at cryogenic temperatures (down to 7 K), matrix and solution photochemistry equipment, infrared, UV and mass spectrometers, as well as modern computational facilities.

This research has resulted in the synthesis and characterization of many novel compounds, including extended cumulenes of the types RN=C=C=C=X, which themselves are used in the synthesis of many novel types of molecules, some of them of potential pharmaceutical interest (quinolone antibiotics; diazepines).

The research group has a world reputation in the field of carbene and nitrene chemistry, involving reactive intermediates with sextet carbon or nitrogen. These species are also very useful in synthesis, for example in the preparation of diazepines and diazepinones, a family of pharmaceutically interesting compounds. Numerous mechanistic studies and synthetic applications of ketenes have been carried out in our group.

Active collaborations are ongoing with scientists in Australia (UQ and CSIRO), China (Suzhou), France (Pau), Germany (Oldenburg), Japan (Hiroshima), Spain (Donostia - San Sebastian), and Portugal (Coimbra).

Availability

Emeritus Professor Curt Wentrup is:
Not available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, Australian National University
  • Doctor of Philosophy of Science (Advanced), University of Copenhagen
  • Doctoral Diploma, unknown
  • Australian Academy of Science, Australian Academy of Science
  • Royal Australian Chemical Institute, Royal Australian Chemical Institute

Research interests

  • Organic, physical, and historical chemistry

    Reactive intermediates, pyrolysis, photochemistry, reaction mechanism. History of science.

Research impacts

This research leads to the development of new pharmaceuticals, e.g. new antibiotics (quinolones and naphthyridones) and new leads towards a treatment for scizophrenia (diazepine molecules).

Chemical industry has used our pyrolysis techniques in specialized manufacturing processes.

Our analytical/spectroscopic work has led to cooperation with chemical and energy firms and agencies involved in forensic science, and our research has generated collaborations with many scientists at universities in Australia, Austria, Belgium, China, Denmark, France, Germany, Hungary, Japan, Portugal, Singapore, Switzerland, and USA.

Works

Search Professor Curt Wentrup’s works on UQ eSpace

432 works between 1966 and 2024

1 - 20 of 432 works

Featured

2023

Journal Article

Johann Rudolph Glauber: the royals’ alchemist and his secret recipes

Wentrup, Curt (2023). Johann Rudolph Glauber: the royals’ alchemist and his secret recipes. Foundations of Chemistry, 26 (1), 3-13. doi: 10.1007/s10698-023-09493-8

Johann Rudolph Glauber: the royals’ alchemist and his secret recipes

Featured

2023

Journal Article

CHNO – formylnitrene, cyanic, isocyanic, fulminic, and isofulminic acids and their interrelationships at DFT and CASPT2 levels of theory

Bégué, Didier, Lafargue-Dit-Hauret, William, Dargelos, Alain and Wentrup, Curt (2023). CHNO – formylnitrene, cyanic, isocyanic, fulminic, and isofulminic acids and their interrelationships at DFT and CASPT2 levels of theory. The Journal of Physical Chemistry A, 127 (43), 9088-9097. doi: 10.1021/acs.jpca.3c05805

CHNO – formylnitrene, cyanic, isocyanic, fulminic, and isofulminic acids and their interrelationships at DFT and CASPT2 levels of theory

Featured

2022

Journal Article

Chemistry, medicine, and gold‐making: Tycho Brahe, Helwig Dieterich, Otto Tachenius, and Johann Glauber

Wentrup, Curt (2022). Chemistry, medicine, and gold‐making: Tycho Brahe, Helwig Dieterich, Otto Tachenius, and Johann Glauber. ChemPlusChem, 88 (1), 1-24. doi: 10.1002/cplu.202200289

Chemistry, medicine, and gold‐making: Tycho Brahe, Helwig Dieterich, Otto Tachenius, and Johann Glauber

Featured

2022

Journal Article

Origins of organic chemistry and organic synthesis

Wentrup, Curt (2022). Origins of organic chemistry and organic synthesis. European Journal of Organic Chemistry, 2022 (25) e202101492. doi: 10.1002/ejoc.202101492

Origins of organic chemistry and organic synthesis

Featured

2020

Journal Article

Zeise, Liebig, Jensen, Hückel, Dewar, and the olefin π-complex bonds

Wentrup, Curt (2020). Zeise, Liebig, Jensen, Hückel, Dewar, and the olefin π-complex bonds. Angewandte Chemie International Edition, 59 (22), 2-13. doi: 10.1002/anie.201913840

Zeise, Liebig, Jensen, Hückel, Dewar, and the olefin π-complex bonds

Featured

2019

Journal Article

Fulminating gold and silver

Wentrup, Curt (2019). Fulminating gold and silver. Angewandte Chemie International Edition, 58 (42), 14800-14808. doi: 10.1002/anie.201906356

Fulminating gold and silver

Featured

2018

Journal Article

Carbenes and nitrenes: recent developments in fundamental chemistry

Wentrup, Curt (2018). Carbenes and nitrenes: recent developments in fundamental chemistry. Angewandte Chemie (International Edition), 57 (36), 11508-11521. doi: 10.1002/anie.201804863

Carbenes and nitrenes: recent developments in fundamental chemistry

Featured

2017

Journal Article

Flash vacuum pyrolysis - techniques and reactions

Wentrup, Curt (2017). Flash vacuum pyrolysis - techniques and reactions. Angewandte Chemie International Edition, 56 (47), 14808-14835. doi: 10.1002/anie.201705118

Flash vacuum pyrolysis - techniques and reactions

Featured

2017

Journal Article

Flash vacuum pyrolysis of azides, triazoles, and tetrazoles

Wentrup, Curt (2017). Flash vacuum pyrolysis of azides, triazoles, and tetrazoles. Chemical Reviews, 117 (5), 4562-4623. doi: 10.1021/acs.chemrev.6b00738

Flash vacuum pyrolysis of azides, triazoles, and tetrazoles

Featured

2016

Journal Article

Rearrangements of 4‑quinolylcarbene, 3‑quinolylcarbene, and 2‑quinolylcarbene to 1 naphthylnitrene and cyanoindenes by falling solid flash vacuum pyrolysis

Aylward, Nigel, Kvaskoff, David, Becker, Jürgen and Wentrup, Curt (2016). Rearrangements of 4‑quinolylcarbene, 3‑quinolylcarbene, and 2‑quinolylcarbene to 1 naphthylnitrene and cyanoindenes by falling solid flash vacuum pyrolysis. The Journal of Organic Chemistry, 81 (11), 4609-4615. doi: 10.1021/acs.joc.6b00444

Rearrangements of 4‑quinolylcarbene, 3‑quinolylcarbene, and 2‑quinolylcarbene to 1 naphthylnitrene and cyanoindenes by falling solid flash vacuum pyrolysis

Featured

2016

Journal Article

Ring contraction in arylcarbenes and arylnitrenes; the rearrangements of 1- and 3-isoquinolylcarbenes and 2-naphthylnitrene to cyanoindenes

Wentrup, Curt, Thétaz, Célestin, Luerssen, Holger, Aylward, Nigel and Kvaskoff, David (2016). Ring contraction in arylcarbenes and arylnitrenes; the rearrangements of 1- and 3-isoquinolylcarbenes and 2-naphthylnitrene to cyanoindenes. The Journal of Organic Chemistry, 81 (11), 4601-4608. doi: 10.1021/acs.joc.6b00442

Ring contraction in arylcarbenes and arylnitrenes; the rearrangements of 1- and 3-isoquinolylcarbenes and 2-naphthylnitrene to cyanoindenes

Featured

2016

Journal Article

Direct Observation of Carbamoylnitrenes

Li, Hongmin, Wan, Huabin, Wu, Zhuang, Li, Dingqing, Bégué, Didier, Wentrup, Curt and Zeng, Xiaoqing (2016). Direct Observation of Carbamoylnitrenes. Chemistry - A European Journal, 22 (23), 7856-7862. doi: 10.1002/chem.201600824

Direct Observation of Carbamoylnitrenes

Featured

2015

Journal Article

Bond-shift isomers: The co-existence of allenic and propargylic phenylnitrile imines

Nunes, Claudio M., Reva, Igor, Fausto, Rui, Begue, Didier and Wentrup, Curt (2015). Bond-shift isomers: The co-existence of allenic and propargylic phenylnitrile imines. Chemical Communications, 51 (79), 14712-14715. doi: 10.1039/c5cc03518j

Bond-shift isomers: The co-existence of allenic and propargylic phenylnitrile imines

Featured

2015

Journal Article

Falling-solid flash vacuum pyrolysis: an efficient preparation of arylacetylenes1

Wentrup, Curt, Becker, Jurgen and Winter, Hans-Wilhelm (2015). Falling-solid flash vacuum pyrolysis: an efficient preparation of arylacetylenes1. Angewandte Chemie, 127 (19), 5794-5796. doi: 10.1002/ange.201412431

Falling-solid flash vacuum pyrolysis: an efficient preparation of arylacetylenes1

2024

Journal Article

Nitrile Imine Cyclizations and Rearrangements: <i>N</i>-Phenyl-<i>C</i>-styrylnitrile Imine and <i>N</i>-Phenyl-<i>C</i>-phenylethynylnitrile Imine

Miri, Maryam, Taherpour, Avat Arman and Wentrup, Curt (2024). Nitrile Imine Cyclizations and Rearrangements: N-Phenyl-C-styrylnitrile Imine and N-Phenyl-C-phenylethynylnitrile Imine. The Journal of Organic Chemistry, 89 (13), 9360-9370. doi: 10.1021/acs.joc.4c00570

Nitrile Imine Cyclizations and Rearrangements: <i>N</i>-Phenyl-<i>C</i>-styrylnitrile Imine and <i>N</i>-Phenyl-<i>C</i>-phenylethynylnitrile Imine

2024

Journal Article

The transition from alchemical to modern chemical symbolism: from Bergman and Guiton de Morveau to Hassenfratz and Adet, Higgins, Richter, Dalton, and Berzelius

Wentrup, Curt (2024). The transition from alchemical to modern chemical symbolism: from Bergman and Guiton de Morveau to Hassenfratz and Adet, Higgins, Richter, Dalton, and Berzelius. ChemPlusChem, 89 (7) e202400033. doi: 10.1002/cplu.202400033

The transition from alchemical to modern chemical symbolism: from Bergman and Guiton de Morveau to Hassenfratz and Adet, Higgins, Richter, Dalton, and Berzelius

2023

Journal Article

Formation of (aza)fulvenallene, cyanocyclopentadiene, and (aza)fluorenes in the thermal rearrangements of indazoles, azaindazoles, and homoquinolinic anhydride

Mirzaei, M. Saeed and Wentrup, Curt (2023). Formation of (aza)fulvenallene, cyanocyclopentadiene, and (aza)fluorenes in the thermal rearrangements of indazoles, azaindazoles, and homoquinolinic anhydride. The Journal of Organic Chemistry, 89 (1), 553-564. doi: 10.1021/acs.joc.3c02289

Formation of (aza)fulvenallene, cyanocyclopentadiene, and (aza)fluorenes in the thermal rearrangements of indazoles, azaindazoles, and homoquinolinic anhydride

2023

Journal Article

Celebrating RACI and Academy of Science awards 2022–23

Wentrup, Curt (2023). Celebrating RACI and Academy of Science awards 2022–23. Australian Journal of Chemistry, 76 (10), 633-634. doi: 10.1071/ch23183

Celebrating RACI and Academy of Science awards 2022–23

2023

Journal Article

The alchemist, metal‐divider and transmuter Carl F. Wenzel and his 1776 award from the Royal Danish Academy of Sciences through Professor C. G. Kratzenstein

Wentrup, Curt (2023). The alchemist, metal‐divider and transmuter Carl F. Wenzel and his 1776 award from the Royal Danish Academy of Sciences through Professor C. G. Kratzenstein. ChemPlusChem, 88 (5) e202300091, 1-11. doi: 10.1002/cplu.202300091

The alchemist, metal‐divider and transmuter Carl F. Wenzel and his 1776 award from the Royal Danish Academy of Sciences through Professor C. G. Kratzenstein

2023

Journal Article

Kekulé’s Oscillating <i>D</i> <sub> 3 <i>h</i> </sub> Cyclohexatriene Structure of Benzene

Wentrup, Curt (2023). Kekulé’s Oscillating D 3 h Cyclohexatriene Structure of Benzene. European Journal of Organic Chemistry, 26 (10) e202201308. doi: 10.1002/ejoc.202201308

Kekulé’s Oscillating <i>D</i> <sub> 3 <i>h</i> </sub> Cyclohexatriene Structure of Benzene

Funding

Past funding

  • 2012 - 2013
    Heron Island Conference on reactive intermediate and unusual molecules
    Ian Potter Foundation
    Open grant
  • 2010
    UQ Travel Awards Category 1, Fabian Borget
    UQ Travel Grants Scheme
    Open grant
  • 2007 - 2009
    Reactive intermediates and microwave-assisted organic reactions
    ARC Discovery Projects
    Open grant
  • 2007
    Research in pre-biotic chemistry
    UQ Travel Grants Scheme
    Open grant
  • 2004
    Research conference grant for Prof Josef Michl, University of Colorado, Boulder, to attend Heron Island Conference on reactive intermediates and unusual molecules, 17-23 July 2004
    Potter Foundation
    Open grant
  • 2004 - 2006
    New mechanisms and methods in carbene and nitrene chemistry
    ARC Discovery Projects
    Open grant
  • 2003 - 2005
    Bimolecular chemistry at very low temperature
    ARC Linkage International
    Open grant
  • 2002
    To expand work on cryogenic matrix isolation research.
    UQ Travel Grants Scheme
    Open grant
  • 2001 - 2003
    Chemistry of Iminopropadienones and Related Compounds.
    ARC Australian Research Council (Large grants)
    Open grant
  • 2000
    Novel approaches to heterocyclic synthesis.
    ARC Australian Research Council (Small grants)
    Open grant
  • 1997
    Brisbane Advanced Mass Spectrometry Facility
    Research Infrastructure (Equip & Fac) Program
    Open grant
  • 1997
    Synthesis of 1,3-diazepines
    ARC Australian Research Council (Small grants)
    Open grant
  • 1996 - 1997
    International Network in Advanced Techniques of Applied Molecular Science
    Quality Funds Round 3
    Open grant
  • 1996
    Pulsed pyrolysis
    ARC Australian Research Council (Small grants)
    Open grant

Supervision

Availability

Emeritus Professor Curt Wentrup is:
Not available for supervision

Supervision history

Completed supervision

  • 2006

    Doctor Philosophy

    SYNTHESES AND REACTIONS OF IMINOPROPADIENONES, SYDNONES AND OXAZINONES

    Principal Advisor

    Other advisors: Professor Craig Williams

  • 2002

    Doctor Philosophy

    HETEROCYCLIC SYNTHESIS BASED ON IMINOPROPADIENONES

    Principal Advisor

  • 2002

    Doctor Philosophy

    SYNTHESIS AND CHARACTERISATION OF 1,3- and 1,4- DIAZEPINES AND DERIVATIVES

    Principal Advisor

  • Doctor Philosophy

    NITRENES REARRANGEMENTS: FORMATION OF REACTIVE INTERMEDIATES AND UNUSUAL MOLECULES

    Principal Advisor

    Other advisors: Professor Craig Williams

Media

Enquiries

Contact Emeritus Professor Curt Wentrup directly for media enquiries about:

  • Organic reaction mechanisms
  • Photochemistry
  • Pyrolysis
  • Reactive intermediates

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