
Overview
Background
Educated at the University of Copenhagen, Denmark, and the Australian National University, Canberra. Career at the Université de Lausanne, Switzerland, and the Universität Marburg, Germany. Professor and Chair of Organic Chemistry and Head of the Organic Chemistry Section, The University of Queensland from 1985. Emeritus professor from 2008. Chair of the National Committee for Chemistry of the Australian Academy of Science 2009-2014. Editor-in-Chief, Australian Journal of Chemistry 2008-15. Editor, Journal of Analytical and Applied Pyrolysis (Elsevier, IF 3.65) 2016-. Visiting Professor Université de Pau, France, 2011-19; Visiting Professor University of Kuwait 2014-18; Visiting Professor / Special Appointed Professor Hiroshima University 2014-18. Fellow of the Australian Academy of Science. Centenary Medal of the Australian Commonwealth 2003 for research in organic and physical chemistry. David Craig Medal of the Academy of Science 2014 for research in chemistry. JSPS Fellowship (Japan) 2014. Honorary doctorate, University of Pau, France, 2014. A.J. Birch Medal of the Royal Australian Chemical Institute (RACI) for ecellence in research in organic chemistry, 2014. Leighton Medal of the RACI 2018.
Research on Unusual Molecules and Reactive Intermediates: Synthesis and Reaction Mechanism. Heterocyclic chemistry. Pyrolysis reactions. Photochemistry
Research in the Wentrup group is concerned with the discovery of novel types of molecules with new and unusual bonding patterns. Such molecules are mostly highly reactive, and special methods are required both for their generation and for their detection. The group has developed these methods over many years and acquired world-class equipment for these purposes, including flash vacuum thermolysis apparatus, cryostats for matrix isolation of reaction products at cryogenic temperatures (down to 7 K), matrix and solution photochemistry equipment, infrared, UV and mass spectrometers, as well as modern computational facilities.
This research has resulted in the synthesis and characterization of many novel compounds, including extended cumulenes of the types RN=C=C=C=X, which themselves are used in the synthesis of many novel types of molecules, some of them of potential pharmaceutical interest (quinolone antibiotics; diazepines).
The research group has a world reputation in the field of carbene and nitrene chemistry, involving reactive intermediates with sextet carbon or nitrogen. These species are also very useful in synthesis, for example in the preparation of diazepines and diazepinones, a family of pharmaceutically interesting compounds. Numerous mechanistic studies and synthetic applications of ketenes have been carried out in our group.
Active collaborations are ongoing with scientists in Australia (UQ and CSIRO), China (Suzhou), France (Pau), Germany (Oldenburg), Japan (Hiroshima), Spain (Donostia - San Sebastian), and Portugal (Coimbra).
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, Australian National University
- Doctor of Philosophy of Science (Advanced), University of Copenhagen
- Doctoral Diploma, Institution to be confirmed
- Australian Academy of Science, Australian Academy of Science
- Royal Australian Chemical Institute, Royal Australian Chemical Institute
Research interests
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Organic, physical, and historical chemistry
Reactive intermediates, pyrolysis, photochemistry, reaction mechanism. History of science.
Research impacts
This research leads to the development of new pharmaceuticals, e.g. new antibiotics (quinolones and naphthyridones) and new leads towards a treatment for scizophrenia (diazepine molecules).
Chemical industry has used our pyrolysis techniques in specialized manufacturing processes.
Our analytical/spectroscopic work has led to cooperation with chemical and energy firms and agencies involved in forensic science, and our research has generated collaborations with many scientists at universities in Australia, Austria, Belgium, China, Denmark, France, Germany, Hungary, Japan, Portugal, Singapore, Switzerland, and USA.
Works
Search Professor Curt Wentrup’s works on UQ eSpace
2016
Journal Article
Twisted C=C double bonds with very low rotational barriers in dioxanediones and isoxazolones determined by low-temperature dynamic NMR spectroscopy and computational chemistry
Wentrup, Curt, Koch, Rainer and Kleinpeter, Erich (2016). Twisted C=C double bonds with very low rotational barriers in dioxanediones and isoxazolones determined by low-temperature dynamic NMR spectroscopy and computational chemistry. European Journal of Organic Chemistry, 2016 (29), 4985-4990. doi: 10.1002/ejoc.201600931
2016
Journal Article
Azulene–naphthalene-type rearrangements in Benz[a]azulene and Cyclohepta[b]indole
Wentrup, Curt and Becker, Jürgen (2016). Azulene–naphthalene-type rearrangements in Benz[a]azulene and Cyclohepta[b]indole. Chemistry - A European Journal, 22 (39), 13835-13839. doi: 10.1002/chem.201603389
2016
Journal Article
Nitrene–nitrene rearrangement under thermal, photochemical, and electron-impact conditions: the 2-azidopyridines/tetrazolo[1,5-a]pyridines
Wentrup, Curt, Braybrook, Carl, Liu, Shanshan, Tzschucke, C. Christoph, Dargelos, Alain and Bégué, Didier (2016). Nitrene–nitrene rearrangement under thermal, photochemical, and electron-impact conditions: the 2-azidopyridines/tetrazolo[1,5-a]pyridines. European Journal of Organic Chemistry, 2016 (24), 4200-4206. doi: 10.1002/ejoc.201600655
2016
Journal Article
Pyrolysis of Benzotriazoles. Relationships between 1- and 2-Vinylbenzotriazoles, α- and β-Azidostyrenes, N-Phenylketenimine and Indole. Pitfalls in the use of Pyrolysis-Mass Spectrometry in Mechanistic Studies
Wentrup, Curt and Freiermuth, Beat (2016). Pyrolysis of Benzotriazoles. Relationships between 1- and 2-Vinylbenzotriazoles, α- and β-Azidostyrenes, N-Phenylketenimine and Indole. Pitfalls in the use of Pyrolysis-Mass Spectrometry in Mechanistic Studies. Journal of Analytical and Applied Pyrolysis, 121, 67-74. doi: 10.1016/j.jaap.2016.07.003
2016
Journal Article
Triazoloazine-diazomethylazine valence isomerization. [1,2,3]triazolo[1,5-a]pyridines and 2-diazomethylpyridines
Aylward, Nigel, Winter, Hans-Wilhelm, Eckhardt, Ulrich and Wentrup, Curt (2016). Triazoloazine-diazomethylazine valence isomerization. [1,2,3]triazolo[1,5-a]pyridines and 2-diazomethylpyridines. Journal of Organic Chemistry, 81 (2), 667-672. doi: 10.1021/acs.joc.5b02639
2016
Journal Article
Celebrating RACI and Academy of Science Awards
Wentrup, Curt (2016). Celebrating RACI and Academy of Science Awards. Australian Journal of Chemistry, 69 (12), 1321-1322. doi: 10.1071/CHv69n12_FO
2015
Journal Article
RACI Research Awards 2014
Wentrup, Curt (2015). RACI Research Awards 2014. Australian Journal of Chemistry, 68 (8), 1173-1173. doi: 10.1071/CH15416
2015
Journal Article
α-Oxo-Iminoxyls of Isoxazolones, Pyrazolones and 1,2,3-Triazolone
Koch, Rainer, Wollweber, Hans-Joachim, Muller-Starke, Hans and Wentrup, Curt (2015). α-Oxo-Iminoxyls of Isoxazolones, Pyrazolones and 1,2,3-Triazolone. European Journal of Organic Chemistry, 2015 (23), 5143-5149. doi: 10.1002/ejoc.201500728
2015
Journal Article
Comment on "The Mechanism of Pyrolysis of Benzyl Azide: Spectroscopic Evidence for Benzenemethanimine Formation"
Wentrup, Curt (2015). Comment on "The Mechanism of Pyrolysis of Benzyl Azide: Spectroscopic Evidence for Benzenemethanimine Formation". Journal of Physical Chemistry A, 119 (29), 8256-8257. doi: 10.1021/acs.jpca.5b04198
2015
Journal Article
C15H10 and C15H12 Thermal Chemistry: Phenanthrylcarbene Isomers and Phenylindenes by Falling Solid Flash Vacuum Pyrolysis of Tetrazoles
Wentrup, Curt, Becker, Jurgen and Diehl, Manfred (2015). C15H10 and C15H12 Thermal Chemistry: Phenanthrylcarbene Isomers and Phenylindenes by Falling Solid Flash Vacuum Pyrolysis of Tetrazoles. Journal of Organic Chemistry, 80 (14), 7144-7149. doi: 10.1021/acs.joc.5b01007
2015
Journal Article
Pyrolysis of annelated hexa- and heptamethylene-tetrazoles: Formation of 9- and 10-membered cyclic carbodiimides
Wentrup, Curt and Vosswinkel, Micheal (2015). Pyrolysis of annelated hexa- and heptamethylene-tetrazoles: Formation of 9- and 10-membered cyclic carbodiimides. Journal of Analytical and Applied Pyrolysis, 117, 214-219. doi: 10.1016/j.jaap.2015.11.013
2015
Journal Article
C9H8 pyrolysis. o-tolylacetylene, indene, 1-indenyl, and biindenyls and the mechanism of indene pyrolysis
Wentrup, Curt, Winter, Hans-Wilhelm and Kvaskoff, David (2015). C9H8 pyrolysis. o-tolylacetylene, indene, 1-indenyl, and biindenyls and the mechanism of indene pyrolysis. Journal of Physical Chemistry A, 119 (24), 6370-6376. doi: 10.1021/acs.jpca.5b03453
2015
Journal Article
Acetylenes from aldehydes. preparation of ethynylphenols and phenylacetylenes by flash vacuum pyrolysis of isoxazolones
Wentrup, Curt, Wiedenstritt, Maria and Winter, Hans-Wilhelm (2015). Acetylenes from aldehydes. preparation of ethynylphenols and phenylacetylenes by flash vacuum pyrolysis of isoxazolones. Australian Journal of Chemistry, 68 (8), 1233-1236. doi: 10.1071/CH15234
2015
Journal Article
Azulenylcarbene and naphthylcarbene isomerizations. falling solid flash vacuum pyrolysis
Kvaskoff, David, Becker, Jurgen and Wentrup, Curt (2015). Azulenylcarbene and naphthylcarbene isomerizations. falling solid flash vacuum pyrolysis. Journal of Organic Chemistry, 80 (10), 5030-5034. doi: 10.1021/acs.joc.5b00412
2015
Journal Article
Oximes in the isoxazolone, pyrazolone, and 1,2,3-triazolone series: experimental and computational investigation of energies and structures of e/z isomers of α-oxo-oximes in the gas phase and in solution
Koch, Rainer, Wollweber, Hans-Joachim and Wentrup, Curt (2015). Oximes in the isoxazolone, pyrazolone, and 1,2,3-triazolone series: experimental and computational investigation of energies and structures of e/z isomers of α-oxo-oximes in the gas phase and in solution. Australian Journal of Chemistry, 68 (9), 1329-1335. doi: 10.1071/CH15095
2015
Journal Article
Direct detection of a triplet vinylnitrene, 1,4-naphthoquinone-2-ylnitrene, in solution and cryogenic matrices
Sarkar, Sujan K, Sawai, Asako, Kanahara, Kousei, Wentrup, Curt, Abe, Manabu and Gudmundsdottir, Anna D (2015). Direct detection of a triplet vinylnitrene, 1,4-naphthoquinone-2-ylnitrene, in solution and cryogenic matrices. Journal of the American Chemical Society, 137 (12), 4207-4214. doi: 10.1021/jacs.5b00998
2015
Journal Article
Comments on photochromism of 3-(3-pyridyl)sydnone and 4-alkenylsydnones
Wentrup, Curt, Kvaskoff, David and Veedu, Rakesh N (2015). Comments on photochromism of 3-(3-pyridyl)sydnone and 4-alkenylsydnones. Journal of Photochemistry and Photobiology A: Chemistry, 298, 62-63. doi: 10.1016/j.jphotochem.2014.10.010
2015
Journal Article
Molecular cleft or tweezer compounds derived from trioxabicyclo[3.3.1]nonadiene diisocyanate and diacid dichloride
Kollenz, Gert, Smounig, Ralf, Belaj, Ferdinand, Kvaskoff, David and Wentrup, Curt (2015). Molecular cleft or tweezer compounds derived from trioxabicyclo[3.3.1]nonadiene diisocyanate and diacid dichloride. Beilstein Journal of Organic Chemistry, 11 (1), 1-8. doi: 10.3762/bjoc.11.1
2015
Journal Article
RACI Congress Adelaide
Wentrup, Curt (2015). RACI Congress Adelaide. Australian Journal of Chemistry, 68 (9), 1317-1318. doi: 10.1071/CH15508
2015
Journal Article
New Year Editorial 2015
Wentrup, Curt (2015). New Year Editorial 2015. Australian Journal of Chemistry, 68 (1), 1-2. doi: 10.1071/CH14678
Funding
Supervision
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
Supervision history
Completed supervision
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2006
Doctor Philosophy
SYNTHESES AND REACTIONS OF IMINOPROPADIENONES, SYDNONES AND OXAZINONES
Principal Advisor
Other advisors: Professor Craig Williams
-
2002
Doctor Philosophy
HETEROCYCLIC SYNTHESIS BASED ON IMINOPROPADIENONES
Principal Advisor
-
2002
Doctor Philosophy
SYNTHESIS AND CHARACTERISATION OF 1,3- and 1,4- DIAZEPINES AND DERIVATIVES
Principal Advisor
-
Doctor Philosophy
NITRENES REARRANGEMENTS: FORMATION OF REACTIVE INTERMEDIATES AND UNUSUAL MOLECULES
Principal Advisor
Other advisors: Professor Craig Williams
Media
Enquiries
Contact Emeritus Professor Curt Wentrup directly for media enquiries about:
- Organic reaction mechanisms
- Photochemistry
- Pyrolysis
- Reactive intermediates
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