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Emeritus Professor Curt Wentrup
Emeritus Professor

Curt Wentrup

Email: 
Phone: 
+61 7 336 53817

Overview

Background

Educated at the University of Copenhagen, Denmark, and the Australian National University, Canberra. Career at the Université de Lausanne, Switzerland, and the Universität Marburg, Germany. Professor and Chair of Organic Chemistry and Head of the Organic Chemistry Section, The University of Queensland from 1985. Emeritus professor from 2008. Chair of the National Committee for Chemistry of the Australian Academy of Science 2009-2014. Editor-in-Chief, Australian Journal of Chemistry 2008-15. Editor, Journal of Analytical and Applied Pyrolysis (Elsevier, IF 3.65) 2016-. Visiting Professor Université de Pau, France, 2011-19; Visiting Professor University of Kuwait 2014-18; Visiting Professor / Special Appointed Professor Hiroshima University 2014-18. Fellow of the Australian Academy of Science. Centenary Medal of the Australian Commonwealth 2003 for research in organic and physical chemistry. David Craig Medal of the Academy of Science 2014 for research in chemistry. JSPS Fellowship (Japan) 2014. Honorary doctorate, University of Pau, France, 2014. A.J. Birch Medal of the Royal Australian Chemical Institute (RACI) for ecellence in research in organic chemistry, 2014. Leighton Medal of the RACI 2018.

Research on Unusual Molecules and Reactive Intermediates: Synthesis and Reaction Mechanism. Heterocyclic chemistry. Pyrolysis reactions. Photochemistry

Research in the Wentrup group is concerned with the discovery of novel types of molecules with new and unusual bonding patterns. Such molecules are mostly highly reactive, and special methods are required both for their generation and for their detection. The group has developed these methods over many years and acquired world-class equipment for these purposes, including flash vacuum thermolysis apparatus, cryostats for matrix isolation of reaction products at cryogenic temperatures (down to 7 K), matrix and solution photochemistry equipment, infrared, UV and mass spectrometers, as well as modern computational facilities.

This research has resulted in the synthesis and characterization of many novel compounds, including extended cumulenes of the types RN=C=C=C=X, which themselves are used in the synthesis of many novel types of molecules, some of them of potential pharmaceutical interest (quinolone antibiotics; diazepines).

The research group has a world reputation in the field of carbene and nitrene chemistry, involving reactive intermediates with sextet carbon or nitrogen. These species are also very useful in synthesis, for example in the preparation of diazepines and diazepinones, a family of pharmaceutically interesting compounds. Numerous mechanistic studies and synthetic applications of ketenes have been carried out in our group.

Active collaborations are ongoing with scientists in Australia (UQ and CSIRO), China (Suzhou), France (Pau), Germany (Oldenburg), Japan (Hiroshima), Spain (Donostia - San Sebastian), and Portugal (Coimbra).

Availability

Emeritus Professor Curt Wentrup is:
Not available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, Australian National University
  • Doctor of Philosophy of Science (Advanced), University of Copenhagen
  • Doctoral Diploma, unknown
  • Australian Academy of Science, Australian Academy of Science
  • Royal Australian Chemical Institute, Royal Australian Chemical Institute

Research interests

  • Organic, physical, and historical chemistry

    Reactive intermediates, pyrolysis, photochemistry, reaction mechanism. History of science.

Research impacts

This research leads to the development of new pharmaceuticals, e.g. new antibiotics (quinolones and naphthyridones) and new leads towards a treatment for scizophrenia (diazepine molecules).

Chemical industry has used our pyrolysis techniques in specialized manufacturing processes.

Our analytical/spectroscopic work has led to cooperation with chemical and energy firms and agencies involved in forensic science, and our research has generated collaborations with many scientists at universities in Australia, Austria, Belgium, China, Denmark, France, Germany, Hungary, Japan, Portugal, Singapore, Switzerland, and USA.

Works

Search Professor Curt Wentrup’s works on UQ eSpace

432 works between 1966 and 2024

41 - 60 of 432 works

2018

Journal Article

Phenylnitrene radical cation rearrangements

Bégué, Didier, Dargelos, Alain and Wentrup, Curt (2018). Phenylnitrene radical cation rearrangements. Journal of Physical Chemistry A: Molecules, Spectroscopy, Kinetics, Environment and General Theory, 122 (43) acs.jpca.8b08480, 8490-8496. doi: 10.1021/acs.jpca.8b08480

Phenylnitrene radical cation rearrangements

2018

Journal Article

Triplet states of tetrazoles, nitrenes, and carbenes from matrix photolysis of tetrazoles, and phenylcyanamide as a source of phenylnitrene

Abe, Manabu, Bégué, Didier, Silva, Hugo Santos, Dargelos, Alain and Wentrup, Curt (2018). Triplet states of tetrazoles, nitrenes, and carbenes from matrix photolysis of tetrazoles, and phenylcyanamide as a source of phenylnitrene. Journal of Physical Chemistry A, 122 (37), 7276-7283. doi: 10.1021/acs.jpca.8b06960

Triplet states of tetrazoles, nitrenes, and carbenes from matrix photolysis of tetrazoles, and phenylcyanamide as a source of phenylnitrene

2018

Journal Article

Carbene und Nitrene: aktuelle Entwicklungen in der Grundlagenchemie

Wentrup, Curt (2018). Carbene und Nitrene: aktuelle Entwicklungen in der Grundlagenchemie. Angewandte Chemie, 130 (36), 11680-11693. doi: 10.1002/ange.201804863

Carbene und Nitrene: aktuelle Entwicklungen in der Grundlagenchemie

2018

Journal Article

Trimethylsilylnitrene and its surprising rearrangement to N-(Dimethylsilyl)methanimine via silaziridine and silaazomethine ylide

Wentrup, Curt, Lüerssen, Holger, Silva, Hugo Santos, Dargelos, Alain and Bégué, Didier (2018). Trimethylsilylnitrene and its surprising rearrangement to N-(Dimethylsilyl)methanimine via silaziridine and silaazomethine ylide. Chemistry: A European Journal, 24 (54), 14547-14553. doi: 10.1002/chem.201803245

Trimethylsilylnitrene and its surprising rearrangement to N-(Dimethylsilyl)methanimine via silaziridine and silaazomethine ylide

2018

Journal Article

Direct observation of an imidoylnitrene: photochemical formation of PhC(=NMe)−N and Me−N from 1-methyl-5-phenyltetrazole

Abe, Manabu, Bégué, Didier, Santos-Silva, Hugo, Dargelos, Alain and Wentrup, Curt (2018). Direct observation of an imidoylnitrene: photochemical formation of PhC(=NMe)−N and Me−N from 1-methyl-5-phenyltetrazole. Angewandte Chemie, 130 (12), 3266-3270. doi: 10.1002/ange.201712689

Direct observation of an imidoylnitrene: photochemical formation of PhC(=NMe)−N and Me−N from 1-methyl-5-phenyltetrazole

2018

Journal Article

First Direct Observation of an Imidoylnitrene. Photochemical Formation of PhC(=NMe)-N and Me-N from 1-Methyl-5-phenyltetrazole

Wentrup, Curt, Abe, Manabu, Bégué, Didier, Santos-Silva, Hugo and Dargelos, Alain (2018). First Direct Observation of an Imidoylnitrene. Photochemical Formation of PhC(=NMe)-N and Me-N from 1-Methyl-5-phenyltetrazole. Angewandte Chemie (International ed. in English), 57 (12), 3212-3216. doi: 10.1002/anie.201712689

First Direct Observation of an Imidoylnitrene. Photochemical Formation of PhC(=NMe)-N and Me-N from 1-Methyl-5-phenyltetrazole

2018

Journal Article

From dipivaloylketene to tetraoxaadamantanes

Kollenz, Gert and Wentrup, Curt (2018). From dipivaloylketene to tetraoxaadamantanes. Beilstein Journal of Organic Chemistry, 14 (1), 1-10. doi: 10.3762/bjoc.14.1

From dipivaloylketene to tetraoxaadamantanes

2018

Journal Article

RACI and academy of science awards 2017-18

Wentrup, Curt (2018). RACI and academy of science awards 2017-18. Australian Journal of Chemistry, 71 (10), 721-722. doi: 10.1071/CHv71n10_FO

RACI and academy of science awards 2017-18

2018

Book Chapter

Flash vacuum pyrolysis

Wentrup, Curt (2018). Flash vacuum pyrolysis. Kirk-Othmer encyclopedia of chemical technology. (pp. 1-28) Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/0471238961.flasmcna.a01.pub2

Flash vacuum pyrolysis

2017

Journal Article

Flash-Vakuumpyrolyse - Techniken und Reaktionen

Wentrup, Curt (2017). Flash-Vakuumpyrolyse - Techniken und Reaktionen. Angewandte Chemie, 129 (47), 15002-15031. doi: 10.1002/ange.201705118

Flash-Vakuumpyrolyse - Techniken und Reaktionen

2017

Journal Article

Pyrolysis of benzotriazoles. 1-Acyl- and 1-alkoxycarbonylbenzotriazoles: Hetero-Wolff rearrangement to N-acyl- and N-alkoxycarbonyl-fulvenimines and free radical routes to cyanocyclopentadienes

Wentrup, Curt, Freiermuth, Beat and Aylward, Nigel (2017). Pyrolysis of benzotriazoles. 1-Acyl- and 1-alkoxycarbonylbenzotriazoles: Hetero-Wolff rearrangement to N-acyl- and N-alkoxycarbonyl-fulvenimines and free radical routes to cyanocyclopentadienes. Journal of Analytical and Applied Pyrolysis, 128, 187-195. doi: 10.1016/j.jaap.2017.10.011

Pyrolysis of benzotriazoles. 1-Acyl- and 1-alkoxycarbonylbenzotriazoles: Hetero-Wolff rearrangement to N-acyl- and N-alkoxycarbonyl-fulvenimines and free radical routes to cyanocyclopentadienes

2017

Journal Article

Celebrating RACI and Academy of Science Awards

Wentrup, Curt (2017). Celebrating RACI and Academy of Science Awards. Australian Journal of Chemistry, 70 (11), 1159-1160. doi: 10.1071/CHv70n11_FO

Celebrating RACI and Academy of Science Awards

2017

Journal Article

Imidoylnitrenes R'C(═NR)-N, Nitrile Imines, 1H-Diazirines, and Carbodiimides: Interconversions and Rearrangements, Structures, and Energies at DFT and CASPT2 Levels of Theory

Bégué, Didier, Santos-Silva, Hugo, Dargelos, Alain and Wentrup, Curt (2017). Imidoylnitrenes R'C(═NR)-N, Nitrile Imines, 1H-Diazirines, and Carbodiimides: Interconversions and Rearrangements, Structures, and Energies at DFT and CASPT2 Levels of Theory. The journal of physical chemistry. A, 121 (43), 8227-8235. doi: 10.1021/acs.jpca.7b08445

Imidoylnitrenes R'C(═NR)-N, Nitrile Imines, 1H-Diazirines, and Carbodiimides: Interconversions and Rearrangements, Structures, and Energies at DFT and CASPT2 Levels of Theory

2017

Journal Article

Iminocyclohexadienylidenes: carbenes or diradicals? the hetero-Wolff rearrangement of benzotriazoles to cyanocyclopentadienes and 1H-benzo[b]azirines

Begue, Didier, Santos-Silva, Hugo, Dargelos, Alain and Wentrup, Curt (2017). Iminocyclohexadienylidenes: carbenes or diradicals? the hetero-Wolff rearrangement of benzotriazoles to cyanocyclopentadienes and 1H-benzo[b]azirines. Journal of Physical Chemistry A, 121 (32), 5998-6003. doi: 10.1021/acs.jpca.7b05325

Iminocyclohexadienylidenes: carbenes or diradicals? the hetero-Wolff rearrangement of benzotriazoles to cyanocyclopentadienes and 1H-benzo[b]azirines

2017

Conference Publication

7th Heron Island conference on reactive intermediates and unusual molecules

Wentrup, Curt and Williams, Craig M. (2017). 7th Heron Island conference on reactive intermediates and unusual molecules. Clayton, VIC, Australia: CSIRO. doi: 10.1071/CH17065

7th Heron Island conference on reactive intermediates and unusual molecules

2017

Journal Article

Pyrolysis of hydrazine derivatives and related compounds with N-N single bonds

Gaber, Abdel-Aal M. and Wentrup, Curt (2017). Pyrolysis of hydrazine derivatives and related compounds with N-N single bonds. Journal of Analytical and Applied Pyrolysis, 125, 258-278. doi: 10.1016/j.jaap.2017.03.016

Pyrolysis of hydrazine derivatives and related compounds with N-N single bonds

2017

Journal Article

New, simple and efficient method for the synthesis of imidazo-azines by flash vacuum thermolysis of tert-butylimines of pyrimidine-2-, pyrazine-2-, quinoline-2-, quinoxaline-2- and isoquinoline-1-carbaldehydes

Justyna, Katarzyna , Chrostowska, Anna , Leśniak, Stanisław , Darrigan, Clovis , Baylère, Patrick , Khayar, Saïd and Wentrup, Curt (2017). New, simple and efficient method for the synthesis of imidazo-azines by flash vacuum thermolysis of tert-butylimines of pyrimidine-2-, pyrazine-2-, quinoline-2-, quinoxaline-2- and isoquinoline-1-carbaldehydes. Journal of Analytical and Applied Pyrolysis, 125, 335-346. doi: 10.1016/j.jaap.2017.02.028

New, simple and efficient method for the synthesis of imidazo-azines by flash vacuum thermolysis of tert-butylimines of pyrimidine-2-, pyrazine-2-, quinoline-2-, quinoxaline-2- and isoquinoline-1-carbaldehydes

2016

Journal Article

A thermally populated, perpendicularly twisted alkene triplet diradical

Wentrup, Curt, Regimbald-Krnel, Michèle J., Müller, Dennis and Comba, Peter (2016). A thermally populated, perpendicularly twisted alkene triplet diradical. Angewandte Chemie, 128 (47), 14820-14825. doi: 10.1002/ange.201607415

A thermally populated, perpendicularly twisted alkene triplet diradical

2016

Journal Article

A Thermally Populated, Perpendicularly Twisted Alkene Triplet Diradical

Wentrup, Curt, Regimbald-Krnel, Michele J., Müller, Dennis and Comba, Peter (2016). A Thermally Populated, Perpendicularly Twisted Alkene Triplet Diradical. Angewandte Chemie, 55 (47), 14600-14605. doi: 10.1002/anie.201607415

A Thermally Populated, Perpendicularly Twisted Alkene Triplet Diradical

2016

Journal Article

Twisted C=C double bonds with very low rotational barriers in dioxanediones and isoxazolones determined by low-temperature dynamic NMR spectroscopy and computational chemistry

Wentrup, Curt, Koch, Rainer and Kleinpeter, Erich (2016). Twisted C=C double bonds with very low rotational barriers in dioxanediones and isoxazolones determined by low-temperature dynamic NMR spectroscopy and computational chemistry. European Journal of Organic Chemistry, 2016 (29), 4985-4990. doi: 10.1002/ejoc.201600931

Twisted C=C double bonds with very low rotational barriers in dioxanediones and isoxazolones determined by low-temperature dynamic NMR spectroscopy and computational chemistry

Funding

Past funding

  • 2012 - 2013
    Heron Island Conference on reactive intermediate and unusual molecules
    Ian Potter Foundation
    Open grant
  • 2010
    UQ Travel Awards Category 1, Fabian Borget
    UQ Travel Grants Scheme
    Open grant
  • 2007 - 2009
    Reactive intermediates and microwave-assisted organic reactions
    ARC Discovery Projects
    Open grant
  • 2007
    Research in pre-biotic chemistry
    UQ Travel Grants Scheme
    Open grant
  • 2004
    Research conference grant for Prof Josef Michl, University of Colorado, Boulder, to attend Heron Island Conference on reactive intermediates and unusual molecules, 17-23 July 2004
    Potter Foundation
    Open grant
  • 2004 - 2006
    New mechanisms and methods in carbene and nitrene chemistry
    ARC Discovery Projects
    Open grant
  • 2003 - 2005
    Bimolecular chemistry at very low temperature
    ARC Linkage International
    Open grant
  • 2002
    To expand work on cryogenic matrix isolation research.
    UQ Travel Grants Scheme
    Open grant
  • 2001 - 2003
    Chemistry of Iminopropadienones and Related Compounds.
    ARC Australian Research Council (Large grants)
    Open grant
  • 2000
    Novel approaches to heterocyclic synthesis.
    ARC Australian Research Council (Small grants)
    Open grant
  • 1997
    Brisbane Advanced Mass Spectrometry Facility
    Research Infrastructure (Equip & Fac) Program
    Open grant
  • 1997
    Synthesis of 1,3-diazepines
    ARC Australian Research Council (Small grants)
    Open grant
  • 1996 - 1997
    International Network in Advanced Techniques of Applied Molecular Science
    Quality Funds Round 3
    Open grant
  • 1996
    Pulsed pyrolysis
    ARC Australian Research Council (Small grants)
    Open grant

Supervision

Availability

Emeritus Professor Curt Wentrup is:
Not available for supervision

Supervision history

Completed supervision

  • 2006

    Doctor Philosophy

    SYNTHESES AND REACTIONS OF IMINOPROPADIENONES, SYDNONES AND OXAZINONES

    Principal Advisor

    Other advisors: Professor Craig Williams

  • 2002

    Doctor Philosophy

    HETEROCYCLIC SYNTHESIS BASED ON IMINOPROPADIENONES

    Principal Advisor

  • 2002

    Doctor Philosophy

    SYNTHESIS AND CHARACTERISATION OF 1,3- and 1,4- DIAZEPINES AND DERIVATIVES

    Principal Advisor

  • Doctor Philosophy

    NITRENES REARRANGEMENTS: FORMATION OF REACTIVE INTERMEDIATES AND UNUSUAL MOLECULES

    Principal Advisor

    Other advisors: Professor Craig Williams

Media

Enquiries

Contact Emeritus Professor Curt Wentrup directly for media enquiries about:

  • Organic reaction mechanisms
  • Photochemistry
  • Pyrolysis
  • Reactive intermediates

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