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Emeritus Professor Curt Wentrup
Emeritus Professor

Curt Wentrup

Email: 
Phone: 
+61 7 336 53817

Overview

Background

Educated at the University of Copenhagen, Denmark, and the Australian National University, Canberra. Career at the Université de Lausanne, Switzerland, and the Universität Marburg, Germany. Professor and Chair of Organic Chemistry and Head of the Organic Chemistry Section, The University of Queensland from 1985. Emeritus professor from 2008. Chair of the National Committee for Chemistry of the Australian Academy of Science 2009-2014. Editor-in-Chief, Australian Journal of Chemistry 2008-15. Editor, Journal of Analytical and Applied Pyrolysis (Elsevier, IF 3.65) 2016-. Visiting Professor Université de Pau, France, 2011-19; Visiting Professor University of Kuwait 2014-18; Visiting Professor / Special Appointed Professor Hiroshima University 2014-18. Fellow of the Australian Academy of Science. Centenary Medal of the Australian Commonwealth 2003 for research in organic and physical chemistry. David Craig Medal of the Academy of Science 2014 for research in chemistry. JSPS Fellowship (Japan) 2014. Honorary doctorate, University of Pau, France, 2014. A.J. Birch Medal of the Royal Australian Chemical Institute (RACI) for ecellence in research in organic chemistry, 2014. Leighton Medal of the RACI 2018.

Research on Unusual Molecules and Reactive Intermediates: Synthesis and Reaction Mechanism. Heterocyclic chemistry. Pyrolysis reactions. Photochemistry

Research in the Wentrup group is concerned with the discovery of novel types of molecules with new and unusual bonding patterns. Such molecules are mostly highly reactive, and special methods are required both for their generation and for their detection. The group has developed these methods over many years and acquired world-class equipment for these purposes, including flash vacuum thermolysis apparatus, cryostats for matrix isolation of reaction products at cryogenic temperatures (down to 7 K), matrix and solution photochemistry equipment, infrared, UV and mass spectrometers, as well as modern computational facilities.

This research has resulted in the synthesis and characterization of many novel compounds, including extended cumulenes of the types RN=C=C=C=X, which themselves are used in the synthesis of many novel types of molecules, some of them of potential pharmaceutical interest (quinolone antibiotics; diazepines).

The research group has a world reputation in the field of carbene and nitrene chemistry, involving reactive intermediates with sextet carbon or nitrogen. These species are also very useful in synthesis, for example in the preparation of diazepines and diazepinones, a family of pharmaceutically interesting compounds. Numerous mechanistic studies and synthetic applications of ketenes have been carried out in our group.

Active collaborations are ongoing with scientists in Australia (UQ and CSIRO), China (Suzhou), France (Pau), Germany (Oldenburg), Japan (Hiroshima), Spain (Donostia - San Sebastian), and Portugal (Coimbra).

Availability

Emeritus Professor Curt Wentrup is:
Not available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, Australian National University
  • Doctor of Philosophy of Science (Advanced), University of Copenhagen
  • Doctoral Diploma, unknown
  • Australian Academy of Science, Australian Academy of Science
  • Royal Australian Chemical Institute, Royal Australian Chemical Institute

Research interests

  • Organic, physical, and historical chemistry

    Reactive intermediates, pyrolysis, photochemistry, reaction mechanism. History of science.

Research impacts

This research leads to the development of new pharmaceuticals, e.g. new antibiotics (quinolones and naphthyridones) and new leads towards a treatment for scizophrenia (diazepine molecules).

Chemical industry has used our pyrolysis techniques in specialized manufacturing processes.

Our analytical/spectroscopic work has led to cooperation with chemical and energy firms and agencies involved in forensic science, and our research has generated collaborations with many scientists at universities in Australia, Austria, Belgium, China, Denmark, France, Germany, Hungary, Japan, Portugal, Singapore, Switzerland, and USA.

Works

Search Professor Curt Wentrup’s works on UQ eSpace

432 works between 1966 and 2024

101 - 120 of 432 works

2013

Journal Article

Matrix-IR spectroscopic investigations of the thermolysis and photolysis of diazoamides

Wentrup, Curt, Bibas, Herve, Kuhn, Arvid, Mitschke, Ullrich and McMills, Mark C. (2013). Matrix-IR spectroscopic investigations of the thermolysis and photolysis of diazoamides. Journal of Organic Chemistry, 78 (21), 10705-10717. doi: 10.1021/jo401695x

Matrix-IR spectroscopic investigations of the thermolysis and photolysis of diazoamides

2013

Journal Article

Iminopropadienones RN=C=C=C=O and bisiminopropadienes RN=C=C=C=NR: Matrix infrared spectra and anharmonic frequency calculations

Begue, Didier, Baraille, Isabelle, Andersen, Heidi Gade and Wentrup, Curt (2013). Iminopropadienones RN=C=C=C=O and bisiminopropadienes RN=C=C=C=NR: Matrix infrared spectra and anharmonic frequency calculations. Journal of Chemical Physics, 139 (16) 164314, 164314.1-164314.9. doi: 10.1063/1.4826647

Iminopropadienones RN=C=C=C=O and bisiminopropadienes RN=C=C=C=NR: Matrix infrared spectra and anharmonic frequency calculations

2013

Journal Article

New reactions of N-tert-butylimines; formation of N-heterocycles by methyl radical elimination on flash vacuum thermolysis of N-benzylidene- and N-(2-pyridyl-methylidene)-tert-butylamines

Vu, Thien Y, Chrostowska, Anna, Huynh, Thi Kieu Xuan, Khayar, Saïd, Dargelos, Alain, Justyna, Katarzyna, Pasternak, Beata, Leśniak, Stanisław and Wentrup, Curt (2013). New reactions of N-tert-butylimines; formation of N-heterocycles by methyl radical elimination on flash vacuum thermolysis of N-benzylidene- and N-(2-pyridyl-methylidene)-tert-butylamines. Chemistry: A European Journal, 19 (44), 14983-14988. doi: 10.1002/chem.201301663

New reactions of N-tert-butylimines; formation of N-heterocycles by methyl radical elimination on flash vacuum thermolysis of N-benzylidene- and N-(2-pyridyl-methylidene)-tert-butylamines

2013

Journal Article

Zwitterionic 1,3-shift intermediates in the interconversions of (thio)carbamoyl isocyanates and carbamoyl iso(thio)cyanates, R2N–CX–NCO ⇌ R2N–CO–NCX, and in carbamoylketenes R2N–CO–CH=C=O

Koch, Rainer and Wentrup, Curt (2013). Zwitterionic 1,3-shift intermediates in the interconversions of (thio)carbamoyl isocyanates and carbamoyl iso(thio)cyanates, R2N–CX–NCO ⇌ R2N–CO–NCX, and in carbamoylketenes R2N–CO–CH=C=O. European Journal of Organic Chemistry, Early View (35), 1-9. doi: 10.1002/ejoc.201300975

Zwitterionic 1,3-shift intermediates in the interconversions of (thio)carbamoyl isocyanates and carbamoyl iso(thio)cyanates, R2N–CX–NCO ⇌ R2N–CO–NCX, and in carbamoylketenes R2N–CO–CH=C=O

2013

Journal Article

Laser-induced carbene-carbene rearrangement in solution: the diphenylcarbene-fluorene rearrangement

Régimbald-Krnel, Michèle J. and Wentrup, Curt (2013). Laser-induced carbene-carbene rearrangement in solution: the diphenylcarbene-fluorene rearrangement. Journal of Organic Chemistry, 78 (17), 8789–8795-8789–8795. doi: 10.1021/jo401607m

Laser-induced carbene-carbene rearrangement in solution: the diphenylcarbene-fluorene rearrangement

2013

Journal Article

Mechanistic diversity in thermal fragmentation reactions: a computational exploration of CO and CO2 extrusions from five-membered rings

Rzepa, Henry S. and Wentrup, Curt (2013). Mechanistic diversity in thermal fragmentation reactions: a computational exploration of CO and CO2 extrusions from five-membered rings. Journal of Organic Chemistry, 78 (15), 7565-7574. doi: 10.1021/jo401146k

Mechanistic diversity in thermal fragmentation reactions: a computational exploration of CO and CO2 extrusions from five-membered rings

2013

Journal Article

4-Pyridylnitrene and 2-pyrazinylcarbene

Wentrup, Curt, Reisinger, Ales and Kvaskoff, David (2013). 4-Pyridylnitrene and 2-pyrazinylcarbene. Beilstein Journal of Organic Chemistry, 9 (23), 754-760. doi: 10.3762/bjoc.9.85

4-Pyridylnitrene and 2-pyrazinylcarbene

2013

Journal Article

3-Pyridylnitrene, 2-and 4-pyrimidinylcarbenes, 3-quinolylnitrenes, and 4-quinazolinylcarbenes. Interconversion, ring expansion to diazacycloheptatetraenes, ring opening to nitrile ylides, and ring contraction to cyanopyrroles and cyanoindoles

Wentrup, Curt, Lan, Nguyen Mong, Lukosch, Adelheid, Bednarek, Pawel and Kvaskoff, David (2013). 3-Pyridylnitrene, 2-and 4-pyrimidinylcarbenes, 3-quinolylnitrenes, and 4-quinazolinylcarbenes. Interconversion, ring expansion to diazacycloheptatetraenes, ring opening to nitrile ylides, and ring contraction to cyanopyrroles and cyanoindoles. Beilstein Journal of Organic Chemistry, 9 (5), 743-753. doi: 10.3762/bjoc.9.84

3-Pyridylnitrene, 2-and 4-pyrimidinylcarbenes, 3-quinolylnitrenes, and 4-quinazolinylcarbenes. Interconversion, ring expansion to diazacycloheptatetraenes, ring opening to nitrile ylides, and ring contraction to cyanopyrroles and cyanoindoles

2013

Journal Article

Rearrangements of Acyl, Thioacyl, and Imidoyl (Thio)cyanates to Iso(thio)cyanates, Acyl Iso(thio)cyanates to (Thio)acyl Isocyanates, and Imidoyl Iso(thio)cyanates to (Thio)acyl Carbodiimides, RCX-YCN reversible arrow RCX-NCY reversible arrow RCY-NCX rever

Koch, Rainer and Wentrup, Curt (2013). Rearrangements of Acyl, Thioacyl, and Imidoyl (Thio)cyanates to Iso(thio)cyanates, Acyl Iso(thio)cyanates to (Thio)acyl Isocyanates, and Imidoyl Iso(thio)cyanates to (Thio)acyl Carbodiimides, RCX-YCN reversible arrow RCX-NCY reversible arrow RCY-NCX rever. Journal of Organic Chemistry, 78 (5), 1802-1810. doi: 10.1021/jo3013786

Rearrangements of Acyl, Thioacyl, and Imidoyl (Thio)cyanates to Iso(thio)cyanates, Acyl Iso(thio)cyanates to (Thio)acyl Isocyanates, and Imidoyl Iso(thio)cyanates to (Thio)acyl Carbodiimides, RCX-YCN reversible arrow RCX-NCY reversible arrow RCY-NCX rever

2013

Journal Article

Chemical activation in azide and nitrene chemistry: methyl azide, phenyl azide, naphthyl azides, pyridyl azides, benzotriazoles, and triazolopyridines

Wentrup, Curt (2013). Chemical activation in azide and nitrene chemistry: methyl azide, phenyl azide, naphthyl azides, pyridyl azides, benzotriazoles, and triazolopyridines. Australian Journal of Chemistry, 66 (8), 852-863. doi: 10.1071/CH13283

Chemical activation in azide and nitrene chemistry: methyl azide, phenyl azide, naphthyl azides, pyridyl azides, benzotriazoles, and triazolopyridines

2013

Journal Article

1,5-(1,7)-biradicals and nitrenes formed by ring opening of hetarylnitrenes

Wentrup, Curt and Kvaskoff, David (2013). 1,5-(1,7)-biradicals and nitrenes formed by ring opening of hetarylnitrenes. Australian Journal of Chemistry, 66 (3), 286-296. doi: 10.1071/CH12502

1,5-(1,7)-biradicals and nitrenes formed by ring opening of hetarylnitrenes

2013

Journal Article

New Year Editorial 2013

Wentrup, Curt (2013). New Year Editorial 2013. Australian Journal of Chemistry, 66 (1), 1-2. doi: 10.1071/CH12554

New Year Editorial 2013

2013

Book Chapter

Matrix studies on aromatic and heteroaromatic nitrenes and their rearrangements

Wentrup, Curt (2013). Matrix studies on aromatic and heteroaromatic nitrenes and their rearrangements. Nitrenes and nitrenium ions. (pp. 273-315) edited by Daniel E. Falvey and Anna D. Gudmundsdottir. Hoboken NJ, United States: John Wiley and Sons Inc.. doi: 10.1002/9781118560907.ch8

Matrix studies on aromatic and heteroaromatic nitrenes and their rearrangements

2012

Journal Article

Mass spectrometry of cyclopentadienylideneketene: differentiation of isomeric ion structures by means of ion/molecule reactions

Gerbaux, Pascal and Wentrup, Curt (2012). Mass spectrometry of cyclopentadienylideneketene: differentiation of isomeric ion structures by means of ion/molecule reactions. Australian Journal of Chemistry, 65 (12), 1655-1661. doi: 10.1071/CH12327

Mass spectrometry of cyclopentadienylideneketene: differentiation of isomeric ion structures by means of ion/molecule reactions

2012

Journal Article

12th Eurasia conference on chemical sciences

Hadjiliadis, Nick and Wentrup, Curt (2012). 12th Eurasia conference on chemical sciences. Australian Journal of Chemistry, 65 (12), 1561-1563. doi: 10.1071/CH12478

12th Eurasia conference on chemical sciences

2012

Journal Article

Methyliminopropadienone CH3-N═C═C═C═O: photoelectron spectrum and electronic structure

Chrostowska, Anna, Dargelos, Alain, Khayar, Said and Wentrup, Curt (2012). Methyliminopropadienone CH3-N═C═C═C═O: photoelectron spectrum and electronic structure. Journal of Physical Chemistry A, 116 (37), 9315-9320. doi: 10.1021/jp307916p

Methyliminopropadienone CH3-N═C═C═C═O: photoelectron spectrum and electronic structure

2012

Journal Article

Synthesis and chemistry of a very stable but reactive diisocyanate, trioxabicyclo[3.3.1]nonadiene diisocyanate

Smounig, Ralph, Leber, Sabine, Kvaskoff, David, Kollenz, Gert and Wentrup, Curt (2012). Synthesis and chemistry of a very stable but reactive diisocyanate, trioxabicyclo[3.3.1]nonadiene diisocyanate. Rsc Advances, 2 (20), 7743-7746. doi: 10.1039/c2ra21073h

Synthesis and chemistry of a very stable but reactive diisocyanate, trioxabicyclo[3.3.1]nonadiene diisocyanate

2012

Journal Article

Synthesis of functionalized macrocyclic derivatives of trioxabicyclo[3.3.0]nonadiene

Leber, Sabine, Kollenz, Gert and Wentrup, Curt (2012). Synthesis of functionalized macrocyclic derivatives of trioxabicyclo[3.3.0]nonadiene. Beilstein Journal of Organic Chemistry, 8 (1), 738-743. doi: 10.3762/bjoc.8.83

Synthesis of functionalized macrocyclic derivatives of trioxabicyclo[3.3.0]nonadiene

2012

Journal Article

Synthesis and structure of a new 1,2-bridged calix[6]arene

Haberz, Peter, Belaj, Ferdinand, Gloe, Karsten, Wentrup, Curt and Kollenz, Gert (2012). Synthesis and structure of a new 1,2-bridged calix[6]arene. Supramolecular Chemistry, 24 (4), 279-284. doi: 10.1080/10610278.2012.658393

Synthesis and structure of a new 1,2-bridged calix[6]arene

2012

Journal Article

Nitrile Imines: Matrix Isolation, IR Spectra, Structures, and Rearrangement to Carbodiimides

Bégué, Didier, Qiao, Greg GuangHua and Wentrup, Curt (2012). Nitrile Imines: Matrix Isolation, IR Spectra, Structures, and Rearrangement to Carbodiimides. Journal of the American Chemical Society, 134 (11), 5339-5350. doi: 10.1021/ja2118442

Nitrile Imines: Matrix Isolation, IR Spectra, Structures, and Rearrangement to Carbodiimides

Funding

Past funding

  • 2012 - 2013
    Heron Island Conference on reactive intermediate and unusual molecules
    Ian Potter Foundation
    Open grant
  • 2010
    UQ Travel Awards Category 1, Fabian Borget
    UQ Travel Grants Scheme
    Open grant
  • 2007 - 2009
    Reactive intermediates and microwave-assisted organic reactions
    ARC Discovery Projects
    Open grant
  • 2007
    Research in pre-biotic chemistry
    UQ Travel Grants Scheme
    Open grant
  • 2004
    Research conference grant for Prof Josef Michl, University of Colorado, Boulder, to attend Heron Island Conference on reactive intermediates and unusual molecules, 17-23 July 2004
    Potter Foundation
    Open grant
  • 2004 - 2006
    New mechanisms and methods in carbene and nitrene chemistry
    ARC Discovery Projects
    Open grant
  • 2003 - 2005
    Bimolecular chemistry at very low temperature
    ARC Linkage International
    Open grant
  • 2002
    To expand work on cryogenic matrix isolation research.
    UQ Travel Grants Scheme
    Open grant
  • 2001 - 2003
    Chemistry of Iminopropadienones and Related Compounds.
    ARC Australian Research Council (Large grants)
    Open grant
  • 2000
    Novel approaches to heterocyclic synthesis.
    ARC Australian Research Council (Small grants)
    Open grant
  • 1997
    Brisbane Advanced Mass Spectrometry Facility
    Research Infrastructure (Equip & Fac) Program
    Open grant
  • 1997
    Synthesis of 1,3-diazepines
    ARC Australian Research Council (Small grants)
    Open grant
  • 1996 - 1997
    International Network in Advanced Techniques of Applied Molecular Science
    Quality Funds Round 3
    Open grant
  • 1996
    Pulsed pyrolysis
    ARC Australian Research Council (Small grants)
    Open grant

Supervision

Availability

Emeritus Professor Curt Wentrup is:
Not available for supervision

Supervision history

Completed supervision

  • 2006

    Doctor Philosophy

    SYNTHESES AND REACTIONS OF IMINOPROPADIENONES, SYDNONES AND OXAZINONES

    Principal Advisor

    Other advisors: Professor Craig Williams

  • 2002

    Doctor Philosophy

    HETEROCYCLIC SYNTHESIS BASED ON IMINOPROPADIENONES

    Principal Advisor

  • 2002

    Doctor Philosophy

    SYNTHESIS AND CHARACTERISATION OF 1,3- and 1,4- DIAZEPINES AND DERIVATIVES

    Principal Advisor

  • Doctor Philosophy

    NITRENES REARRANGEMENTS: FORMATION OF REACTIVE INTERMEDIATES AND UNUSUAL MOLECULES

    Principal Advisor

    Other advisors: Professor Craig Williams

Media

Enquiries

Contact Emeritus Professor Curt Wentrup directly for media enquiries about:

  • Organic reaction mechanisms
  • Photochemistry
  • Pyrolysis
  • Reactive intermediates

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