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Professor David Ascher

Deputy Associate Dean Research (Research Partnerships)
Faculty of Science
NHMRC Emerging Leadership Fellow
School of Chemistry and Molecular Biosciences
Faculty of Science
Availability:
Available for supervision
Media expert

Prof David Ascher is currently an NHMRC Investigator and Director of the Biotechnology Program at the University of Queensland. He is also Head of Computational Biology and Clinical Informatics at the Baker Institute.

David’s research focus is in modelling biological data to gain insight into fundamental biological processes. One of his primary research interests has been developing tools to unravel the link between genotype and phenotype, using computational and experimental approaches to understand the effects of mutations on protein structure and function. His group has developed a platform of over 40 widely used programs for assessing the molecular consequences of coding variants (>7 million hits/year).

Working with clinical collaborators in Australia, Brazil and UK, these methods have been translated into the clinic to guide the diagnosis, management and treatment of a number of hereditary diseases, rare cancers and drug resistant infections.

David has a B.Biotech from the University of Adelaide, majoring in Biochemistry, Biotechnology and Pharmacology and Toxicology; and a B.Sci(Hon) from the University of Queensland, majoring in Biochemistry, where he worked with Luke Guddat and Ron Duggleby on the structural and functional characterization of enzymes in the branched-chain amino acid biosynthetic pathway. David then went to St Vincent’s Institute of Medical Research to undertake a PhD at the University of Melbourne in Biochemistry. There he worked under the supervision of Michael Parker using computational, biochemical and structural tools to develop small molecules drugs to improve memory.

In 2013 David went to the University of Cambridge to work with Sir Tom Blundell on using fragment based drug development techniques to target protein-protein interactions; and subsequently on the structural characterisation of proteins involved in non-homologous DNA repair. He returned to Cambridge in 2014 to establish a research platform to characterise the molecular effects of mutations on protein structure and function- using this information to gain insight into the link between genetic changes and phenotypes. He was subsequently recruited as a lab head in the Department of Biochemistry and Molecular Biology at the University of Melbourne in 2016, before joining the Baker Institute in 2019 and the University of Queensland in 2021.

He is an Associate Editor of PBMB and Fronteirs in Bioinformatics, and holds honorary positions at Bio21 Institute, Cambridge University, FIOCRUZ, and the Tuscany University Network.

David Ascher
David Ascher

Dr Melinda Ashcroft

Research Fellow (Climate Change)
Greenslopes Clinical Unit
Faculty of Medicine
Availability:
Available for supervision

Dr Melinda Ashcroft is a Research Fellow on Infectious Disease Epidemiology (Climate Change) in the Faculty of Medicine at The University of Queensland (UQ). Her current research focus is on Nontuberculous mycobacteria (NTM) and how NTM infections are associated with climate change and major weather events. Previously Melinda has worked at Monash University as a Research Fellow on the Sero-epidemiology of Klebsiella spp., at the University of Melbourne as a Postdoctoral Research Fellow on the Genomic Epidemiology of Neisseria gonorrhoeae and as a Research Associate at UQ on the genomics and epigenomics of extraintestinal pathogenic Escherichia coli. Melinda was awarded a Bachelor of Applied Science (Biotechnology/Biochemistry) in 2004 from Queensland University of Technology and a Master of Biotechnology in 2013 from UQ. She then switched fields to Microbial Genomics and was awarded a PhD from UQ in 2019 for her thesis: Evolution and function of mobile genetic elements and DNA methyltransferases in extraintestinal pathogenic Escherichia coli.

Melinda Ashcroft
Melinda Ashcroft

Dr Daniel Edge-Garza

Postdoctoral Research Fellow - Apple Genomics
Centre for Animal Science
Queensland Alliance for Agriculture and Food Innovation
Availability:
Available for supervision

Dr Daniel Edge-Garza is a horticulture and crop geneticist at the Queensland Alliance for Agriculture and Food Innovation at the University of Queensland, Australia. His research interests are to develop and translate tools using genome-wide DNA information for breeders and growers to make meaningful decisions. Daniel’s PhD awarded by the University of Queensland in 2024 focused on identifying global G x E patterns to assist with improved germplasm-environment matching for commercial deployment. Before joining QAAFI, he obtained his Bachelor's Degree in Biological Sciences in 2005 and Master's Degree in Biotechnology in 2009 both at California State University, Fresno. From 2008, he worked as a faculty associate in research for tree fruit breeding at Washington State University becoming recognized worldwide for his efforts to streamline the deployment of DNA tests for pome and stone fruit breeding programs. He has also collaborated with the Genome Database for Rosaceae since 2018 to curate genomics data and train breeders on how to upload and access their data on the Breeding Information Management System.

Daniel Edge-Garza
Daniel Edge-Garza

Dr Patrick Mason

Postdoctoral Research Fellow
Centre for Horticultural Science
Queensland Alliance for Agriculture and Food Innovation
Postdoctoral Research Fellow
Centre for Crop Science
Queensland Alliance for Agriculture and Food Innovation
Availability:
Available for supervision
Patrick Mason
Patrick Mason

Dr Elizabeth Ross

Senior Research Fellow
Centre for Animal Science
Queensland Alliance for Agriculture and Food Innovation
Availability:
Not available for supervision
Elizabeth Ross
Elizabeth Ross