Overview
Background
Dr Melinda Ashcroft is a Research Fellow on Infectious Disease Epidemiology (Climate Change) in the Faculty of Medicine at The University of Queensland (UQ). Her current research focus is on Nontuberculous mycobacteria (NTM) and how NTM infections are associated with climate change and major weather events. Previously Melinda has worked at Monash University as a Research Fellow on the Sero-epidemiology of Klebsiella spp., at the University of Melbourne as a Postdoctoral Research Fellow on the Genomic Epidemiology of Neisseria gonorrhoeae and as a Research Associate at UQ on the genomics and epigenomics of extraintestinal pathogenic Escherichia coli. Melinda was awarded a Bachelor of Applied Science (Biotechnology/Biochemistry) in 2004 from Queensland University of Technology and a Master of Biotechnology in 2013 from UQ. She then switched fields to Microbial Genomics and was awarded a PhD from UQ in 2019 for her thesis: Evolution and function of mobile genetic elements and DNA methyltransferases in extraintestinal pathogenic Escherichia coli.
Availability
- Dr Melinda Ashcroft is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Applied Science, Queensland University of Technology
- Masters (Coursework) of Biotechnology, The University of Queensland
- Doctor of Philosophy of Microbiology, The University of Queensland
- Member, American Society for Microbiology, American Society for Microbiology
- Member, Australian Bioinformatics and Computational Biology Society, Australian Bioinformatics and Computational Biology Society
- Member, Australian Society for Microbiology, Australian Society for Microbiology
Works
Search Professor Melinda Ashcroft’s works on UQ eSpace
2024
Journal Article
The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen
White, Rhys T., Ashcroft, Melinda M., Bauer, Michelle J., Bell, Jan, Butkiewicz, Dominika, Álvarez-Fraga, Laura, Gibson, Justine S., Kidsley, Amanda K., Mollinger, Joanne L., Peters, Kate M., Phan, Minh-Duy, Roberts, Leah W., Rogers, Benjamin A., Schembri, Mark A., Trott, Darren J., Turnidge, John, Forde, Brian M. and Beatson, Scott A. (2024). The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen. Access Microbiology, 6 (10). doi: 10.1099/acmi.0.000894.v3
2024
Other Outputs
The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen.
White, Rhys T., Ashcroft, Melinda A., Bauer, Michelle J., Bell, Jan, Butkiewicz, Dominika, Álvarez-Fraga, Laura, Gibson, Justine S., Kidsley, Amanda K., Mollinger, Joanne L., Peters, Kate M., Phan, Duy, Roberts, Leah W., Rogers, Benjamin, Schembri, Mark, Trott, Darren J., Turnidge, John, Forde, Brian M. and Beatson, Scott A. (2024). The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen.. doi: 10.1099/acmi.0.000894.v2
2024
Journal Article
Genomic epidemiology reveals geographical clustering of multidrug-resistant Escherichia coli ST131 associated with bacteraemia in Wales
White, Rhys T., Bull, Matthew J., Barker, Clare R., Arnott, Julie M., Wootton, Mandy, Jones, Lim S., Howe, Robin A., Morgan, Mari, Ashcroft, Melinda M., Forde, Brian M., Connor, Thomas R. and Beatson, Scott A. (2024). Genomic epidemiology reveals geographical clustering of multidrug-resistant Escherichia coli ST131 associated with bacteraemia in Wales. Nature Communications, 15 (1) 1371, 1-10. doi: 10.1038/s41467-024-45608-1
2021
Journal Article
Reflex detection of ciprofloxacin resistance in Neisseria gonorrhoeae by use of the SpeeDx ResistancePlus GC assay
Lee, Darren Y.J., Ashcroft, Melinda M., Chow, Eric P.F., Sait, Michelle, De Petra, Vesna, Tschaepe, Marlene, Lange, Sigrid, Taiaroa, George, Bradshaw, Catriona S., Whiley, David M., Fairley, Christopher K., Howden, Benjamin P., Chen, Marcus Y., Pasricha, Shivani and Williamson, Deborah A. (2021). Reflex detection of ciprofloxacin resistance in Neisseria gonorrhoeae by use of the SpeeDx ResistancePlus GC assay. Journal of Clinical Microbiology, 59 (5) e00089-21. doi: 10.1128/JCM.00089-21
2020
Journal Article
Incidence and duration of incident oropharyngeal gonorrhoea and chlamydia infections among men who have sex with men: prospective cohort study
Chow, Eric P F, Vodstrcil, Lenka A, Williamson, Deborah A, Maddaford, Kate, Hocking, Jane S, Ashcroft, Melinda, De Petra, Vesna, Bradshaw, Catriona S and Fairley, Christopher K (2020). Incidence and duration of incident oropharyngeal gonorrhoea and chlamydia infections among men who have sex with men: prospective cohort study. Sexually Transmitted Infections, 97 (6), 452-457. doi: 10.1136/sextrans-2020-054764
2020
Other Outputs
Genomic assessment of within-host population variation in Neisseria gonorrhoeae: implications for gonorrhoea transmission
Ashcroft, Melinda M., Chow, Eric P. F., Lee, Darren Y. J., De Petra, Vesna, Soumilas, Maree, Tschaepe, Marlene, Zhang, Lei, Ingle, Danielle J., Taiaroa, George, Hicks, Allison L., Grad, Yonatan H., Howden, Benjamin P., Fairley, Christopher K. and Williamson, Deborah A. (2020). Genomic assessment of within-host population variation in Neisseria gonorrhoeae: implications for gonorrhoea transmission. doi: 10.1101/2020.08.24.20181230
2020
Journal Article
Targeted surveillance strategies for efficient detection of novel antibiotic resistance variants
Hicks, Allison L., Kissler, Stephen M., Mortimer, Tatum D., Ma, Kevin C., Taiaroa, George, Ashcroft, Melinda, Williamson, Deborah A., Lipsitch, Marc and Grad, Yonatan H. (2020). Targeted surveillance strategies for efficient detection of novel antibiotic resistance variants. eLife, 9 e56367. doi: 10.7554/eLife.56367
2020
Other Outputs
Strain and lineage-level methylome heterogeneity in the multi-drug resistant pathogenic Escherichia coli ST101 clone
Ashcroft, Melinda M., Forde, Brian M., Phan, Minh-Duy, Peters, Kate M., Roberts, Leah W., Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Paterson, David L., Walsh, Timothy R., Schembri, Mark A. and Beatson, Scott A. (2020). Strain and lineage-level methylome heterogeneity in the multi-drug resistant pathogenic Escherichia coli ST101 clone. doi: 10.1101/2020.06.07.138552
2020
Other Outputs
Genomic characterisation and context of the blaNDM-1 carbapenemase in Escherichia coli ST101
Ashcroft, Melinda M., Forde, Brian M., Phan, Minh-Duy, Peters, Kate M., Henderson, Andrew, Hancock, Steven J., Roberts, Leah W., White, Rhys T., Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Paterson, David L., Walsh, Timothy R., Schembri, Mark A. and Beatson, Scott A. (2020). Genomic characterisation and context of the blaNDM-1 carbapenemase in Escherichia coli ST101. doi: 10.1101/860726
2020
Conference Publication
GENOMIC ASSESSMENT OF WITHIN-HOST POPULATION VARIATION IN <i>NEISSERIA GONORRHOEAE</i>: IMPLICATIONS FOR GONORRHOEA TRANSMISSION
Ashcroft, M. M., Chow, E. P. F., Lee, D. Y. J., Taiaroa, G., Howden, B. P., Fairley, C. K. and Williamson, D. A. (2020). GENOMIC ASSESSMENT OF WITHIN-HOST POPULATION VARIATION IN NEISSERIA GONORRHOEAE: IMPLICATIONS FOR GONORRHOEA TRANSMISSION. CLAYTON: CSIRO PUBLISHING.
2020
Conference Publication
INCIDENCE AND DURATION OF INCIDENT OROPHARYNGEAL GONORRHOEA AND CHLAMYDIA INFECTIONS AMONG MEN WHO HAVE SEX WITH MEN: A PROSPECTIVE COHORT STUDY
Chow, E. P. F., Vodstrcil, L. A., Williamson, D. A., Maddaford, K., Hocking, J. S., Ashcroft, M. M., De Petra, , Bradshaw, C. S. and Fairley, C. K. (2020). INCIDENCE AND DURATION OF INCIDENT OROPHARYNGEAL GONORRHOEA AND CHLAMYDIA INFECTIONS AMONG MEN WHO HAVE SEX WITH MEN: A PROSPECTIVE COHORT STUDY. CLAYTON: CSIRO PUBLISHING.
2019
Other Outputs
Evolution and function of mobile genetic elements and DNA methyltransferases in extraintestinal pathogenic Escherichia coli
Ashcroft, Melinda (2019). Evolution and function of mobile genetic elements and DNA methyltransferases in extraintestinal pathogenic Escherichia coli. PhD Thesis, School of Chemistry and Molecular Biosciences, The University of Queensland. doi: 10.14264/uql.2019.128
2018
Journal Article
Genetic variation in IRF4 expression modulates growth characteristics, tyrosinase expression and interferon-gamma response in melanocytic cells
Chhabra, Yash, Yong, Hilary X. L., Fane, Mitchell E., Soogrim, Arish, Lim, Wen, Mahiuddin, Dayana Nur, Kim, Reuben S. Q., Ashcroft, Melinda, Beatson, Scott A., Ainger, Stephen A., Smit, Darren J., Jagirdar, Kasturee, Walker, Graeme J., Sturm, Richard A. and Smith, Aaron G. (2018). Genetic variation in IRF4 expression modulates growth characteristics, tyrosinase expression and interferon-gamma response in melanocytic cells. Pigment Cell & Melanoma Research, 31 (1), 51-63. doi: 10.1111/pcmr.12620
2016
Journal Article
Erratum for Ben Zakour et al., Sequential Acquisition of Virulence and Fluoroquinolone Resistance Has Shaped the Evolution of Escherichia coli ST131
Ben Zakour, Nouri L, Alsheikh-Hussain, Areej S, Ashcroft, Melinda M, Khanh Nhu, Nguyen Thi, Roberts, Leah W, Stanton-Cook, Mitchell, Schembri, Mark A and Beatson, Scott A (2016). Erratum for Ben Zakour et al., Sequential Acquisition of Virulence and Fluoroquinolone Resistance Has Shaped the Evolution of Escherichia coli ST131. mBio, 7 (3), 1-1. doi: 10.1128/mBio.00958-16
2016
Journal Article
Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of Escherichia coli ST131
Ben Zakour, Nouri L., Alsheikh-Hussain, Areej S., Ashcroft, Melinda M., Nhu, Nguyen Thi Khanh, Roberts, Leah W., Stanton-Cook, Mitchell, Schembri, Mark A. and Beatson, Scott A. (2016). Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of Escherichia coli ST131. MBio, 7 (2) e00347-16, e00347-16.1-e00347-16.11. doi: 10.1128/mBio.00347-16
2015
Journal Article
Lineage-specific methyltransferases define the methylome of the globally disseminated Escherichia coli ST131 clone
Forde, Brian M., Phan, Minh-Duy, Gawthorne, Jayde A., Ashcroft, Melinda M., Stanton-Cook, Mitchell, Sarkar, Sohinee, Peters, Kate M., Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Upton, Mathew, Schembri, Mark A. and Beatson, Scott A. (2015). Lineage-specific methyltransferases define the methylome of the globally disseminated Escherichia coli ST131 clone. MBio, 6 (6) e01602-15, e01602-15. doi: 10.1128/mBio.01602-15
Supervision
Availability
- Dr Melinda Ashcroft is:
- Available for supervision
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Media
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