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I completed my Bachelor of Pharmacy at Kings College London, followed by pre-registration and subsequent employment as a pharmacist with Boots the Chemists in Central London. With a PhD in plant biochemistry with Royal Holloway College, University of London, and the Royal Botanic Gardens, Kew, I moved first to Cornell University, USA and then The University of Western Australia for postdoctoral research. I moved to the School of Pharmacy at The University of Queensland in 2007.

Following a number of years in plant research, my current research interests generally link back to plants in some way. Many of my projects develop in response to requests for help from healthcare professionals, and so I have a strong focus on answering clinical questions using pharmaceutical science methods. See my research interests for more information.

I teach into the Bachelor of Pharmacy (Honours) in the areas of pharmaceutics, compounding and complementary medicines. I also teach the clinical drug development course for our Master of Pharmaceutical Industry Practice. I am currently the Director of Teaching, Learning and Student Experience for the School of Pharmacy. I have supervised 28 PhD students to completion, and over 60 undergraduate and masters independent research project students.

Assoc. Prof. Stephan is an anatomist and forensic anthropologist with research interests in skeletal analysis and identification in the medicolegal setting. Specifcally these research interests include: craniofacial identification, radiographic comparison, trauma, unmingling of skeletons, biological profile estimations and standards of practice. Carl heads the Laboratory for Human Craniofacial and Skeletal Identification (HuCS-ID Lab), and is Chief Anatomist at The University of Queensland (UQ) School of Anatomy.

Carl is a Fellow of The American Academy of Forensic Sciences and recent past President of the International Association of Craniofacial Identification. Carl served as Special Issue Managing Guest Editor for Forensic Science International, Latest Progress in Craniofacial Identification, 2018. He has been Editorial Board Member of the Journal of Forensic Sciences (2013-23) and Associate Editor of Forensic Anthropology (2016-20). Carl founded the SBMS Skeletal Collection and Skeletisation Program at UQ in late 2014, re-energising forensic osteology within the UQ School of Anatomy and more broadly within the School of Biomedical Sciences.

Carl's prior appointments include forensic anthropology analyst with the Iraq Mass Graves Investigation Team (USA Army Corps of Engineers on behalf of the USA Department of Justice) and ORISE researcher at the USA Department of Defence Central Identification Laboratory in Hawaii. He often now serves as an external consultant to the USA Defence POW/MIA Accounting Agency (DPAA). At UQ and as Chief Anatomist and School of Anatomy manager, Carl works very closely with the SBMS Gross Anatomy Facility, in all matters of anatomy teaching, research and governance management.

Working in joint with the GAF Manager, Carl has cross adapted ISO17025 style practices and auditing procedures to the UQ School of Anatomy space and introduced the first Code-of-Practice for Use of Human Tissues within the UQ School of Anatomy since its inauguration (1927). These accreditation-style policies and procedures are further implemented and expanded in the HuCS-ID Lab, providing vital learning experiences and skill sets for Honours and Higher Research Degree students wanting to pursue careers in forensic science. New data analytic, casework and research tools developed by the HuCS-ID Lab and in the statistical environment of R, are freely and routinely released for others to use at the website: CRANIOFACIALidentification.com.

Carl's research outputs currently exceed 100 total scientific publications, including more than 85 full-length research articles..

Michele Sterling is a NHMRC Leadership Fellow (leadership level 2), Professor in the Recover Injury Research Centre, Program Lead of the Musculoskeletal Injury research program and Director of the NHMRC Centre of Research Excellence (CRE) in Better Health Outcomes for Compensable Injury. She is a Musculoskeletal Physiotherapist and a Fellow of the Australian College of Physiotherapists. She is internationally recognised for her research on whiplash-associated disorders. Michele’s research focusses on the mechanisms underlying the development of chronic pain after injury, predictive algorithms for outcomes and developing effective interventions for musculoskeletal injury and pain. She has received over $50M in research funding from the NHMRC, MRFF, ARC and industry partners, including 7 NHMRC project grants, and 2 Centres of Research Excellence. Michele holds editorial roles with several leading journals and textbooks, including being a Section Editor of PAIN and co-editors of the 4th and 5th editions of the seminal physiotherapy textbook 'Grieve's Musculoskeletal Physiotherapy). Michele has published over 325 scientific works and has received numerous awards for her research including the Research Australia Research Translation award in 2023. Examples of recognition as a national and international leader in the field include:

2024- Secretary of the Executive Council - International Association for the Study of Pain (IASP)

2022-2024 Chair Scientific Program Committee World Pain Congress, Amsterdam 2024

2023-2027 NHMRC Leadership Fellow (Level 2) for research of road traffic injury.

2023 Research Australia Research Translation award

2016-2022 Council member International Association for the Study of Pain (IASP)

Associate Professor Steyn is a leading expert in neurodegenerative disease research, specializing in the metabolic and physiological aspects of Motor Neurone Disease (MND). He currently directs a comprehensive translational research program at the University of Queensland, focusing on the interplay between metabolism and disease progression in MND, and leads key projects investigating the impact of metabolic dysfunction, appetite dysregulation, and hypermetabolism on patient outcomes. His work prioritizes the integration of pre-clinical models, clinical studies, and innovative digital health technologies to advance understanding of the heterogeneity in MND, patient care and therapeutic development.

Associate Professor Steyn’s career began with detailed investigations into the hypothalamic regulation of energy homeostasis, growth, and reproduction. He developed industry-standard methodologies for evaluating hormone release patterns in rodent models, particularly concerning growth hormone regulation. In 2015, he transitioned to focus on neurodegenerative diseases, establishing a research platform at UQ that has significantly advanced the analysis of metabolic phenotypes in MND.

His current research projects include the MEND-MND study, which explores how altered energy metabolism influences disease progression, and the EATT4MND study, which examines the consequences of appetite loss and impaired body weight regulation on disease outcomes. Through collaboration with industry partners, he is also developing novel therapeutic strategies and refining wearable digital health technologies for precise, real-time monitoring of disease progression, including the validation of actigraphy-based measures as clinical trial biomarkers.

I am a medicinal and organic chemist

Studied organic chemistry at the University of Sydney, moved to UQ in 1993, then worked for Bayer in Germany, before moving back to Australia in 1996. Worked in Melbourne at the Victorian College of Pharmacy (now MIPS). I then returned to UQ in 2000 to the Fairlie lab where we design and synthesise new chemical entities to tackle human disease. Since 2012 I have been on extended medical leave and am currently an Adjunct Research Fellow, researching proteins from flaviviruses such as Dengue, West Nile, and Zika viruses, and the coronaviruses SARS, MERS, and SARS-CoV-2.

Dr Nicole Stormon is a Senior Lecturer at the University of Queensland and AHPRA registered Oral health therapist. The current and inaugural Program Convenor for the School of Dentistry’s Doctor of Dental Medicine. She is also the Principal Research Fellow for Queensland Health Metro North Community and Oral Health. An alumnus of the University of Queensland for her undergraduate and postgraduate training, Nicole has become an internationally recognised leader and advocate in Oral Health Therapy.

Nicole Stormon has publications in high quality journals, numerous conference presentation and research collaborations. Health service research is a central theme of her research, with ongoing collaborations with Queensland Health to develop evidence-based and cost-effective models of dental care. She has extensive experience in the analysis of complex quantitative health service data and large longitudinal cohort studies. Additionally, Nicole is experienced in relevant health services research methods including qualitative, scoping methods and consumer engagement. Translating evidence into practice can be challenging, however her research aims to implement innovations and generate new knowledge to better patients oral health outcomes. Being a clinician herself and her effective collaborations to the health service are key to bridging the knowledge-implementation gap.

Nicole Stormon represents the oral health workforce and applies expertise, leadership and governance skills. As an advocate for oral health, she has consulted on a number of national oral health policy issues. Called as an expert witness into the Aged Care Royal Commission into oral health. She has contributed to countless written submissions and representations on national and local advocacy and policy matters. As a leader and advocate for her profession, saw through the recognition and implementation of oral health professionals in obtaining provider numbers and claiming within the Child Dental Benefits Schedule. She has contributed to ongoing public policy issues and has published evaluations of the federal funding policy the Child Dental Benefits.

Professor Jennifer Stow is a molecular cell biologist, an NHMRC Leadership Fellow and head of the Protein Trafficking and Inflammation research laboratory in The University of Queensland’s Institute of Molecular Bioscience (IMB). Her previous leadership appointments include as Division Head and Deputy Director (Research) at IMB (12 years) and she currently serves on national and international advisory boards, editorial boards and steering committees, and as an elected Associate Member of the European Molecular Biology Organisation (EMBO).

Jenny Stow received her undergraduate and PhD qualifications at Melbourne’s Monash University before undertaking postdoctoral training in the Department of Cell Biology at Yale University School of Medicine, USA. With training as a microscopist in kidney research, she gained further experience at Yale as a postdoc in the lab of eminent cell biologist and microscopist, Dr Marilyn Farquhar, where protein trafficking was both a theme and a passion. Jenny then took up her first faculty appointment as an Assistant Professor in the Renal Unit at Massachusetts General Hospital (MGH) and Harvard Medical School in Boston USA, where her research uncovered new roles for a class of enzymes, GTPases, in regulating trafficking within cells. At MGH her research also formed part of a highly successful NIH Renal Cell Biology Program. In late 1994, Jenny moved her research lab back to Australia, to The University of Queensland, in late 1994 as a Wellcome Trust International Medical Research Fellow. As part of IMB since, the Stow lab has continued a focus on protein trafficking, including pioneering live-cell imaging, to spearhead their work on trafficking in inflammation, cancer and chronic disease. Major discoveries include identifying new proteins and pathways for recycling adhesion proteins in epithelial cells, inflammatory cytokine secretion in macrophages and immune signalling through Toll-like receptors in inflammation and infection. Small GTPases of the Rab family, signalling adaptors and kinases feature among the molecules studied in the Stow lab for their functional roles and their potential as drug targets in inflammation and cancer. A keen focus is to understand the role of the fluid uptake pathway, macropinocytosis, in controlling inflammation, cancer and mucosal absorption.

Professor Stow has been awarded multiple career fellowships including from American Heart Association, Wellcome Trust and NHMRC. She has published >200 papers, cited over 15,500 times and she is the recipient of awards and honours, most recently including the 2019 President's Medal from the Australia and New Zealand Society for Cell and Developmental Biology. She is also academic head of IMB Microscopy, a world-class fluorescence microscopy and image analysis facility. Her research is funded by a variety of agencies and industry partnerships, in addition to NHMRC and ARC, including through the ARC Centre of Excellence in Quantum Biotechnology, QUBIC. The Stow lab work with national and international collaborators and welcome students and postdoctoral trainees to participate in their research. We value having a diverse, inclusive and supportive culture for research and celebrate the many diverse and wonderful successes of Stow lab alumni.

MS has 35 years clinical research experience in pathogenesis and management of hypertension (HT), including endocrine varieties such as primary aldosteronism (PA). Working within the Greenslopes Hospital Hypertension Unit (GHHU), he helped demonstrate that PA is 10 times more common than previously thought and to account for approximately 10% of HT, making it the commonest specifically treatable, potentially curable variety, and in the description of a new familial form (FH-II) which recently led to the elucidation of its genetic basis (a gain of function mutation in CLCN2, published in Nature Genetics). The combined GHHU/Princess Alexandra Hospital HT Unit (PAHHU, which MS set up in 2000) has possibly the largest series (>2500) worldwide of patients with PA who have been thoroughly documented and meticulously studied, helping MS to become internationally recognized as an authority on pathogenesis/genetics, diagnostic workup and management of PA. In 2006, MS served as member of an international Task Force sponsored by the US Endocrine Society to develop the first guideline for diagnosis and management of PA (published in J Clin Endocrinol Metab and cited >1200 times with an update published in 2016 and cited >1900 times). He is currently Co-Chair of the working group for the third guideline. MS conceived, developed and validated the seated saline suppression test which has since become the favoured method for definitively confirming the diagnosis of PA in most Australian and in a rapidly growing number of overseas institutions. He has also made major contributions to the understanding of how various physiological and pharmacological factors affect the aldosterone/renin ratio as a screening test for PA and in optimizing approaches to adrenal venous sampling, the most reliable method of differentiating unilateral (surgically curable) from bilateral varieties.

Publications: MS has published 1 book, 20 textbook chapters and >250 papers in peer-reviewed scientific journals. His journal publications have been cited >14,000 times ("h" index 59).

Grant Support: Since 2019, MS has received ~$16 million in research grant support. He is currently a CI on two MRFF grants and an NHMRC CCRE.

Invited Presentations and Collaboration: MS has been invited to speak at major meetings 137 times (99 international) and has collaborated with researchers in >20 international Units and all Australian states. In 2018, was one of six investigators awarded a highly prestigious Leducq Foundation Transatlantic Networks of Excellence Program grant ($USD 6 million) to study the role of potassium in hypertension.

Committee Highlights: MS is past President of the Asian-Pacific Society of Hypertension and of the High Blood Pressure Research Council of Australia. During his time as HBPRCA President, initiatives that were introduced under his presidency included launching of a successful bid for 24h ABPM to be assigned an item number to enable a Medicare rebate of ABPM services. He was a Member of the NHF BP & Vascular Disease Advisory Committee 1998-2013.

Community Engagement: As President since 1995 of the Queensland Hypertension Association, a non-profit organization dedicated to promoting self-care in the management of hypertension, MS has overseen all of its activities, including bimonthly educational sessions and preparation of educational material for the general community and health professionals. On numerous occasions, MS has provided information to the community on issues related to hypertension by media interview.

Peer Review: Previously serving on Editorial Boards for of J Clin Endocrinol Metab, J Hypertens, Clin Exper Pharmacol Physiol, and Nephology, MS is currently Editor-in-Chief of J Hum Hypertens and a member of the Editorial Board for Hypertension. He has assessed 100’s of manuscripts for major international journals and served as grant application assessor on many occasions for major international and national funding bodies (including the NHMRC).

Other Awards and Honours: (1) John W.H. Tyrer Prize for Research in Internal Medicine, (2) Robert Vandongen Memorial Lecturer (University of WA), 2002, (3) Honorary Professor to the Xinjiang Institute of Hypertension, 2005, (4) Visiting Professor to the Tung Wah Eastern Hospital, Hong Kong, 2008, (5) Gaston Bauer Lecturer, Cardiac Society of Australia and New Zealand, 2012, (5) Nimmo Visitor, Royal Adelaide Hospital, 2015, (6) Paul Korner Award, Hypertension Australia, 2024.

Jenny was appointed Professor of Occupational Therapy in 1997. At the end of 2015, Jenny took early retirement from UQ. In January 2016, she was awarded the title of Emeritus Professor of The University of Queensland. Jenny is now using her time to facilitate and enable a new generation of clinical occupational therapists to appraise and utilise research evidence in their practice, and to conduct clinical research and generate new evidence to inform practice. In addition, she continues to guide a growing group of research higher degree students, while focusing more time upon her own research in the area of chronic pain.

Her research has primarily focused upon the impact which chronic pain has upon a person's life; the attendant measurement of that pain, and the efficacy of different treatment approaches. Jenny was recognised as a Distinguished Member of the Australian Pain Society in 2014, for her contribution to pain management education and research in Australia.

Professor David Sturgess is the Deputy Director of Anaesthesia (Professional Development) at the Princess Alexandra Hospital, Brisbane, Australia. He is also a Councillor (Non-executive Director) of the Australia and New Zealand College of Anaesthetists (ANZCA), as well as Medical lead & Co-chair of the Queensland Health Statewide Anaesthesia and Perioperative Network (SWAPNet).

Professor Sturgess' doctoral thesis focused upon the non-invasive evaluation of heart function during life threatening infection. This culminated in award of a Doctorate of Philosophy (PhD), in the Discipline of Anaesthesiology and Critical Care, from The University of Queensland. Professor Sturgess maintains a keen interest in haemodynamic monitoring and echocardiography.

The scope of his current research interests has broadened and is best collated under the theme of Perioperative Medicine. Professor Sturgess' research brings together elements of the inflammatory response, critical care equipment and inter-professional collaboration.

Postgraduate research student supervision and published collaborations include exploration of the interactions between opioids, regional anaesthesia and cancer recurrance; perioperative nutrition and hyperglycaemia; analysis and interpretation of large observational perioperative datasets; risk stratification of acute coronary syndromes using echocardiography; neuraxial anatomy and haemodynamics relevent to peripartum anaesthesia; implementation science and perioperative temperature monitoring and management.

Dr Michalis Stylianou is a senior lecturer with the School of Human Movement and Nutrition Sciences at The University of Queensland. His research interests focus around creating active and healthy schools using comprehensive and coordinated approaches that involve school staff, parents, and the community. Michalis is also a member of the Active Healthy Kids Australia research working group, a collaboration among Australian children’s physical activity and health researchers who advocate for actions to increase the physical activity levels among Australian children using the Physical Activity Report Card for Children and Young People as the core monitoring metric.

I am a biologist interested in the general question of how changes in developmental processes can lead to evolutionary variation and origin of complex traits (such as neural circuits). I study development and evolution of the brain of mammals. My doctoral thesis studied brain regions involved in olfactory and pheromonal communication in mammals. I discovered several events of parallel co-variation of sensory pathways in distantly related species sharing similar ecological niches, as cases of ontogenetic and phylogenetic plasticity. Currently, I study development and evolution of neocortical circuits by following two main lines of research: one aims to determine how early neuronal activity emerges during development and help shape brain connections, and the other one aims to understand what developmental processes led to evolutionary innovations in the mammalian brain. My research combines molecular development (electroporation, CRISPR), transcriptomics, sensory manipulations, neuroanatomy mapping (MRI, stereotaxic tracer injections, confocal and image analysis), optogenetics, and in vivo calcium imaging (multiphoton and widefield) in rodent pups and marsupial joeys.

Critical Care Medicine focuses on supporting patients, often with one or multiple organ failures. Based at the largest Australian cardiac hospital, our research investigates better ways to support patients with heart and/or lung failure. We explore technological, pharmacological and engineering advances that could help our patients to live longer and better. Our group is world-renowned for clinically relevant large animal models, including heart failure, respiratory failure (ARDS), heart transplantation, sepsis, cardiogenic shock, and more. All our studies use hospital-grade equipment and follow the same clinical guideline to maximise translation. We actively take on honours, MPhil and PhD students from multi-disciplinary backgrounds (science, engineering, medicine, allied health), with a successful track record in supporting our students to secure their own grants and funding. Students are expected to contribute to other studies of the group. For more information about the group, please visit ccrg.org.au, and email if you are interested to join us.

Dr Daniel Sullivan is a Clinical Psychologist and Adjunct Lecturer in the Child Health Research Centre, The University of Queensland. In his clinical role, Dr Sullivan leads a program of research to design Australia's first psychology extended scope of practice model of care for limited pharmacotherapy management, with an emphasis on deprescribing hypnotic medicines in the public sector sleep psychology setting (ExPEDiTe Sleep project). As a member of the Let’s Yarn about Sleep group at the University of the Sunshine Coast, Dr Sullivan is working to improve sleep health equity for First Nations Australians through community co-designed, culturally responsive sleep programs which harmonise sleep science with Indigenous Australian perspectives and knowledges about sleep.

Dr Sullivan’s research and clinical expertise is in the behavioural aspects of sleep; he is an Editor of the journal Research Directions: Sleep Psychology (Cambridge University Press) and is board certified by the US-based Board of Behavioral Sleep Medicine. Dr Sullivan completed postgraduate training in sleep at the University of Sydney (MSc), and his PhD in Clinical Psychology at Griffith University, where his doctoral research examined psychological factors involved in sleep-related headaches.

Professor Clair Sullivan is an internationally-recognised leading practising and academic clinical informatician who helps drive digital health transformation in Queensland and globally.

Clair is the Director of the new Queensland Digital Health Centre within the Centre for Health Research at The University of Queensland.

A specialist endocrinologist, Clair graduated with Honours in Medicine from The University of Queensland and earned a Research Doctorate in Medicine from the University of Leeds. In 2014, Clair began a parallel career in the emerging field of digital health and has held significant leadership roles in digital health practice and governance across government and academia. Her work is regularly translated into practice and informs policy in Australia and globally.

Clair was appointed Associate Professor of Medicine in Clinical Informatics at UQ and is an Adjunct Professor at the Faculty of Health, Queensland University of Technology and an Adjunct Professor, School of Health and Biomedical Sciences at Royal Melbourne Institute of Technology.

She is a fellow of the Royal Australasian College of Physicians, the Australian College of Health Informatics and the Australasian Institute of Digital Health.

Clair serves on several national advisory boards for digital health. She is the recipient of several awards including the 2021 Premier’s Award for Excellence for her team’s work on the digital response to COVID-19 and the 2022 Telstra Brilliant Connected Women in Digital Health Award.

She has generated over $30M in grant funding and has deep collaborations with government and industry. She is ranked in the top 1% of Medical Informatics researchers globally.

Professor Yasmina Sultanbawa's research is focused within the agribusiness development framework, specifically in the area of food processing, preservation, food safety and nutrition. Her current research includes the minimisation of post harvest losses through value addition and the search for natural preservatives to replace current synthetic chemicals. In addition, her research area also includes the challenge of nutrition security, in particular micronutrient deficiency (hidden hunger), lack of diet diversity and nutritional losses in the food supply chain, which are addressed by her work with underutilized Australian plant species and potential new crops. Her work on Australian native plant foods is focused on incorporation of these plants in mainstream agriculture and diet diversification Working with indigenous communities to develop nutritious and sustainable value added products from native plants for use in the food, feed, cosmetic and health care industries is a key strategy. The creation of employment, economic and social benefits to these remote communities is an anticipated outcome. She considers it a privilege to engage with these communities and is very passionate that her work will have a positive socio-economic impact.

Research Focus

• Functional ingredients (natural additives)

Functional food/feed/nutraceutical ingredients with enhanced nutritional and phytochemical profiles are obtained from specialty crops (Australian native plant foods) and industry co/by-products. Natural additives are obtained from raw materials of vegetable, fruit, herbs/spices or microbiological origin. An example is plant extracts which can provide e.g. antioxidants, shelf-life extension (natural antimicrobials), trace-nutrients (vitamins/ minerals) and novel flavours. Innovative technology solutions

• Novel packaging systems

Development of active, biodegradable packaging material with natural additives for shelf life extension, smart packaging with nanosensors for the effective detection of food contaminants, microperforated packaging systems with optimised modified atmospheres for fresh foods and high barrier packaging material for herbs and spices are practical objectives of her research. Engineered nano-delivery systems for plant bioactives Develop nano-platforms for targeted delivery and controlled release of plant bioactives including antioxidant and antimicrobial products, through testing of in vitro activities and shelf life under various conditions.

• Photodynamic treatment

Photodynamic treatment or photosensitization is a novel light and photo dye based approach which offers promising alternatives to conventional methods for the control of microorganisms. Plant bioactives such as curcumin has been successfully used to control mycrotoxigenic fungi. This technology has potential as a decontamination tool to reduce the microbial load in food and feed.

• Food safety

Her research focus in this field includes intervention strategies to inhibit and prevent food-borne pathogens and spoilage organisms in fresh food and beverages, elucidating mechanisms of antimicrobial action, shelf-life extension with natural antimicrobials, retaining bioactivity during processing and storage, search for natural inhibitors from Australian native plants, use of bioactive honey from Leptospermum polygalifolium (Jelly bush) in treating microbial wound infections.

Dr Hongfu Sun completed his PhD in Biomedical Engineering at the University of Alberta in 2015, followed by postdoctoral training in Calgary until 2018. He joined the Imaging, Sensing and Biomedical Engineering team in the School of ITEE at UQ in 2019 and was awarded the ARC DECRA fellowship in 2021. His research interests include developing novel magnetic resonance imaging (MRI) contrast mechanisms, e.g. Quantitative Susceptibility Mapping (QSM), fast and multi-parametric MRI acquisitions, and advanced image reconstruction techniques, including deep learning and artificial intelligence, to advance medical imaging techniques for clinical applications.

Dr Sun is currently recruiting graduate students. Check out Available Projects for details. Open to both Domestic and International students.

Matt Sweet is an NHMRC Leadership Fellow, Group Leader, and Director of Higher Degree Research (DHDR) at the Institute for Molecular Bioscience (IMB) at The University of Queensland, Brisbane, Australia. He was the founding Director of the IMB Centre for Inflammation and Disease Research (2014-2018), also serving as Deputy Head of the IMB Division of Cell Biology and Molecular Medicine during this period. Matt studies innate immunity, the body’s danger sensing system that responds to infection, injury and dysregulated homeostasis, and the role of this system in health and disease. Matt’s research team focuses on manipulating the innate immune system for the development of anti-infective and anti-inflammatory strategies. To do so, his lab characterizes the roles of specific innate immune pattern recognition receptors and their downstream signalling pathways/gene products in inflammatory disease processes, as well as in host responses to bacterial pathogens. He has authored >175 journal articles and book chapters, including in Science (2), Science Translational Medicine, Science Immunology, Nature Immunology, Nature Genetics, Nature Communications (4), PNAS USA (6) and Journal of Experimental Medicine (2), and his career publications have accrued >19,000 citations.

Biography

I was awarded a PhD (The University of Queensland) in 1996 for my research under the supervision of Prof David Hume into gene regulation in macrophages, immune cells with important roles in health and disease. I subsequently undertook a short postdoctoral position in the same laboratory, focusing on the activation of macrophages by pathogen products. I then embarked on a CJ Martin post-doctoral training fellowship with Prof Eddy Liew, FRS at the University of Glasgow in Scotland. Returning to The University of Queensland, I had a prominent role within the Cooperative Research Centre for Chronic Inflammatory Diseases (including as UQ node head from 2007-2008) and was appointed as a Group Leader at the IMB in 2007. I have continued fellowship support since this time, including as an ARC Future Fellow, an NHMRC Senior Research Fellow and an NHMRC Leadership Fellow (current, from 2021).

Key discoveries

CpG-containing DNA as an activator of innate immunity, and characterization of the receptor (TLR9) detecting this microbial component.

The IL-1 receptor family member ST2 as a critical regulator of innate immunity and inflammation.

Inflammatory and antimicrobial functions of histone deacetylase enzymes (HDACs) in macrophages.

Effects of the growth factor CSF-1 on inflammatory responses in macrophages.

Mechanisms responsible for divergence in TLR responses between human and mouse macrophages, as well as the functional consequences of such divergence.

TLR-inducible zinc toxicity as an antimicrobial weapon of macrophages and the identification of defects in this pathway in cystic fibrosis.

Host evasion strategies used by the bacterial pathogens Salmonella enterica serovar Typhimurium and uropathogenic E. coli.

SCIMP as a novel TLR adaptor that mediates TLR tyrosine phosphorylation and selective cytokine outputs.

Genes and pathways associated with the severity of chronic liver disease.

Molecular mechanisms controlling macrophage immunometabolism, as well as associated inflammatory and antimicrobial responses.

Anti-inflammatory and antibacterial activities of the metabolite ribulose-5-phosphate.

Research training

I have supervised or co-supervised 29 completed PhD students and 22 completed honours students, as well as 9 post-doctoral researchers. Many of my former staff and students continue to have active research careers around the world (USA, UK, Europe, Australia), including as independent laboratory heads. I currently supervise 5 PhD students in my laboratory, co-supervise 4 PhD students in other laboratories, and oversee the research activities of 2 post-doctoral researchers in my group. Current and former staff/students have received numerous fellowships and awards during their research careers (e.g. ARC DECRA, NHMRC CJ Martin fellowship, UQ post-doctoral fellowship, Smart State scholarship). I have also examined >25 PhD theses in the fields of innate immunity, inflammation and host defence.

Professional activities

I am an editorial board member of the Journal of Leukocyte Biology and Seminars in Cell & Developmental Biology, and have served as an editorial board member for several other journals in the past e.g. Immunology and Cell Biology. I have served on NHMRC project grant review panels in 2007, 2008, 2009, 2012 (as panel chair) and 2014, NHMRC Ideas panels in 2020 and 2024, NHMRC Investigator panels in 2021 and 2022, as well as a member of the NHMRC RGMS user reference group committee from 2010-2012. I acted as national representative for the Australasian Society of Immunology (ASI) Infection and Immunity special interest group from 2012-2017. At UQ, I served as chair of an animal ethics committee from 2013-2014, and co-organized the UQ Host-Pathogen interaction network from 2007-2010 (prior to the establishment of the Australian Infectious Diseases Research Centre). I am currently Director of Higher Degree by Research at IMB, overseeing HDR student recruitment and training.

I have made extensive contributions to conference organization in my discipline. I co-organized the national TLROZ2009 and TLROZ2012 conferences, I organized the first ever Australasian Society for Immunology (ASI) Infection and Immunity workshop (2009), was chair of the ASI Program Committee and co-organizer of the Infection and Immunity workshop for ASI2017, and I co-organized the annual IMB Inflammation Symposium (2014-2018). I also co-chaired the 2019 World Conference of Inflammation (Sydney, September 2019). In addition, I have been a member of the organizing committee for ASI2009, the 2014 International Cytokine and Interferon Society conference, the Lorne Infection and Immunity conference (2014-2020), and the Brisbane Immunology Group annual meeting (2008 to the present).