Overview
Background
Dr Parker's fundamental research interest is the improved healthcare of infants and children through evidence-based drug dosing. Dr Parker is a bioanalyst with 20 years of experience designing methods to measure drugs in biological fluids, positioning her to develop kinder, less-invasive sampling methods that can improve the feasibility of clinical dosing studies. Dr Parker’s research career has furthered these laboratory skills into a translational framework: by applying innovation in microsampling her research will define evidence-based antibiotic dosing regimens.
Availability
- Dr Suzanne Parker is:
- Available for supervision
Qualifications
- Bachelor of Applied Science, Queensland University of Technology
- Postgraduate Diploma, The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research impacts
To advance her research program, in 2016 Dr Parker established the Clinical Microsampling Group. Her research and experience is cross-disciplinary - based in infectious diseases, pharmacokinetic modelling and bioanalysis
Dr Parker has a series of important publications culminating in the characterization of fosfomycin, an antibiotic vital for the treatment of multi-drug resistant pathogens. This provided crucial evidence for effective dosing of this antibiotic in critically ill patients and advanced change in clinical practice. Dr Parker’s research has also produced world-first evidence essential for the implementation of microsampling in a clinical environment. Dr Parker has developed population pharmacokinetic models for clinical collaborators to describe dosing of drugs in challenging patient groups.
Works
Search Professor Suzanne Parker’s works on UQ eSpace
2024
Journal Article
The impact of extracorporeal support on antimicrobial pharmacokinetics in critically ill neonatal and paediatric patients: a systematic review
Cree, Michele L., Abdul-Aziz, Mohd Hafiz, Schlapbach, Luregn J., Roberts, Jason A. and Parker, Suzanne (2024). The impact of extracorporeal support on antimicrobial pharmacokinetics in critically ill neonatal and paediatric patients: a systematic review. International Journal of Antimicrobial Agents, 64 (4) 107311, 1-16. doi: 10.1016/j.ijantimicag.2024.107311
2024
Journal Article
Optimized fosfomycin regimens for treating carbapenem‐resistant <i>Acinetobacter baumannii</i> in critically ill patients with varying degrees of renal function
Tidwong, Nattapong, Chanruang, Anan, Chupradit, Suthanya, Parker, Suzanne L., Leelawattanachai, Pannee, Winichakoon, Poramed and Punyawudho, Baralee (2024). Optimized fosfomycin regimens for treating carbapenem‐resistant Acinetobacter baumannii in critically ill patients with varying degrees of renal function. Clinical and Translational Science, 17 (10). doi: 10.1111/cts.70038
2024
Journal Article
Population pharmacokinetics of unbound cefazolin in infected hospitalized patients requiring intermittent high-flux haemodialysis: can a three-times-weekly post-dialysis dosing regimen provide optimal treatment?
Duke, Carleigh, Parker, Suzanne L, Zam, Betty B, Chiong, Fabian, Sajiv, Cherian, Pawar, Basant, Ashok, Aadith, Cooper, Brynley P, Tong, Steven Y C, Janson, Sonja, Wallis, Steven C, Roberts, Jason A and Tsai, Danny (2024). Population pharmacokinetics of unbound cefazolin in infected hospitalized patients requiring intermittent high-flux haemodialysis: can a three-times-weekly post-dialysis dosing regimen provide optimal treatment?. Journal of Antimicrobial Chemotherapy. doi: 10.1093/jac/dkae318
2024
Journal Article
Can capillary microsampling facilitate a clinical pharmacokinetics study of cefazolin in critically ill children?
Dorofaeff, Tavey, Valero, Yarmarly Guerra, Coulthard, Mark G, Wallis, Steven C, Chatfield, Mark D, Lister, Paula, Lipman, Jeffrey, Roberts, Jason A and Parker, Suzanne L (2024). Can capillary microsampling facilitate a clinical pharmacokinetics study of cefazolin in critically ill children?. Bioanalysis, ahead-of-print (ahead-of-print), 1-9. doi: 10.1080/17576180.2024.2377912
2024
Journal Article
Population pharmacokinetics of prophylactic cefoxitin in elective bariatric surgery patients: a prospective monocentric study
Novy, Emmanuel, Liu, Xin, Hernandez-Mitre, Maria Patricia, Belveyre, Thibaut, Scala-Bertola, Julien, Roberts, Jason A. and Parker, Suzanne L. (2024). Population pharmacokinetics of prophylactic cefoxitin in elective bariatric surgery patients: a prospective monocentric study. Anaesthesia Critical Care and Pain Medicine, 43 (3) 101376, 1-8. doi: 10.1016/j.accpm.2024.101376
2024
Journal Article
Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis
Ngougni Pokem, Perrin, Liu, Xin, Parker, Suzanne L., Verroken, Alexia, Collienne, Christine, Finet, Patrice, Wijnant, Gert-Jan, Laterre, Pierre-François, Roberts, Jason A., Van Bambeke, Françoise and Wittebole, Xavier (2024). Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis. Journal of Antimicrobial Chemotherapy, 79 (2), 429-442. doi: 10.1093/jac/dkad398
2023
Journal Article
Population pharmacokinetics of fluconazole in critically ill patients receiving extracorporeal membrane oxygenation and continuous renal replacement therapy: an ASAP ECMO study
Novy, Emmanuel, Abdul-Aziz, Mohd H., Cheng, Vesa, Burrows, Fay, Buscher, Hergen, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Levkovich, Bianca J., McGuinness, Shay, Ordonez, Jenny, Parke, Rachael, Parker, Suzanne, Pellegrino, Vincent, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Fraser, John F., Shekar, Kiran and Roberts, Jason A. (2023). Population pharmacokinetics of fluconazole in critically ill patients receiving extracorporeal membrane oxygenation and continuous renal replacement therapy: an ASAP ECMO study. Antimicrobial Agents and Chemotherapy, 68 (1) e0120123, e0120123. doi: 10.1128/aac.01201-23
2023
Journal Article
Validating a novel three-times-weekly post-hemodialysis ceftriaxone regimen in infected Indigenous Australian patients—a population pharmacokinetic study
Tsai, Danny, Zam, Betty B., Tongs, Carleigh, Chiong, Fabian, Sajiv, Cherian, Pawar, Basant, Ashok, Aadith, Cooper, Brynley P, Tong, Steven Y C, Janson, Sonja, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2023). Validating a novel three-times-weekly post-hemodialysis ceftriaxone regimen in infected Indigenous Australian patients—a population pharmacokinetic study. Journal of Antimicrobial Chemotherapy, 78 (8), 1963-1973. doi: 10.1093/jac/dkad190
2023
Journal Article
Is the pharmacokinetics of first-line anti-TB drugs a cause of high mortality rates in TB patients admitted to the ICU? A non-compartmental pharmacokinetic analysis
Beraldi-Magalhaes, Francisco, Parker, Suzanne L., Sanches, Cristina, Garcia, Leandro Sousa, Souza Carvalho, Brenda Karoline, Costa, Amanda Araujo, Fachi, Mariana Millan, de Liz, Marcus Vinicius, de Souza, Alexandra Brito, Safe, Izabella Picinin, Pontarolo, Roberto, Wallis, Steven, Lipman, Jeffrey, Roberts, Jason A. and Cordeiro-Santos, Marcelo (2023). Is the pharmacokinetics of first-line anti-TB drugs a cause of high mortality rates in TB patients admitted to the ICU? A non-compartmental pharmacokinetic analysis. Tropical Medicine and Infectious Disease, 8 (6) 312, 1-10. doi: 10.3390/tropicalmed8060312
2023
Journal Article
Stability of nafamostat in intravenous infusion solutions, human whole blood and extracted plasma: implications for clinical effectiveness studies
Hernández-Mitre, María Patricia, Won, Hayoung, Wallis, Steven C., Parker, Suzanne L. and Roberts, Jason A. (2023). Stability of nafamostat in intravenous infusion solutions, human whole blood and extracted plasma: implications for clinical effectiveness studies. Bioanalysis, 15 (12), 673-681. doi: 10.4155/bio-2023-0040
2023
Journal Article
Serum creatinine and tacrolimus assessment with VAMS finger-prick microsampling: a diagnostic test study
Scuderi, Carla E., Parker, Suzanne L., Jacks, Margaret, John, George T., McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew J., Healy, Helen G., Roberts, Jason A. and Staatz, Christine E. (2023). Serum creatinine and tacrolimus assessment with VAMS finger-prick microsampling: a diagnostic test study. Kidney Medicine, 5 (4) 100610, 100610. doi: 10.1016/j.xkme.2023.100610
2023
Journal Article
Evaluation of a closed loop-blood sampling system in intensive care: A pilot randomised controlled trial. The ENCLOSE trial
Keogh, Samantha, Dhanani, Jayesh, Levido, Annabel, Gracie, Chris, Ilushin, Vladislav, Palmer, Jennifer, Doubrovsky, Anna, Parker, Suzanne L., Pintara, Alexander, Huygens, Flavia and Coyer, Fiona (2023). Evaluation of a closed loop-blood sampling system in intensive care: A pilot randomised controlled trial. The ENCLOSE trial. Intensive and Critical Care Nursing, 75 103364, 1-8. doi: 10.1016/j.iccn.2022.103364
2023
Journal Article
Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients
Adiraju, Santosh K. S., Sumi, Chandra D., Pandey, Saurabh, Cotta, Menino O., Roberts, Jason A, Lipman, Jeffrey, Wallis, Steven C. and Parker, Suzanne L. (2023). Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients. Bioanalysis, 15 (1), 31-42. doi: 10.4155/bio-2022-0230
2023
Conference Publication
Improving tuberculosis treatment using mid-infrared spectroscopy for bedside therapeutic drug monitoring
Rowe, David J., Owens, Daniel R., Nedeljkovic, Milos, Stirling, Callum J., Cathie, Katrina, Parker, Suzanne L., Faust, Saul N., Mashanovich, Goran Z. and Wilkinson, James S. (2023). Improving tuberculosis treatment using mid-infrared spectroscopy for bedside therapeutic drug monitoring. Silicon Photonics XVIII 2023, San Francisco, CA United States, 30 January - 1 February 2023. Bellingham, WA United States: International Society for Optical Engineering. doi: 10.1117/12.2649135
2023
Conference Publication
Does renal replacement therapy impact the clearance of meropenem, piperacillin, tazobactam and vancomycin in a critically ill child? An ex vivo study
Cree, Michele, Schlapbach, Luregn, Sumi, Chandra, Wallis, Steve, Roberts, Jason and Parker, Suzanne (2023). Does renal replacement therapy impact the clearance of meropenem, piperacillin, tazobactam and vancomycin in a critically ill child? An ex vivo study. ANZICS/ACCCN Intensive Care Annual Scientific Meeting, Adelaide, SA Australia, 29-31 March 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2023.07.020
2023
Conference Publication
Are meropenem, piperacillin, tazobactam and vancomycin sequestered onto a paediatric extracorporeal membrane oxygenation circuit? An ex vivo study
Cree, Michele, Haisz, Emma, Sumi, Chandra, Wallis, Steve, Schlapbach, Luregn, Roberts, Jason and Parker, Suzanne (2023). Are meropenem, piperacillin, tazobactam and vancomycin sequestered onto a paediatric extracorporeal membrane oxygenation circuit? An ex vivo study. ANZICS/ACCCN Intensive Care Annual Scientific Meeting, Adelaide, SA Australia, 29-31 March 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2023.07.023
2023
Journal Article
Population pharmacokinetics and dosing simulations of ampicillin and sulbactam in hospitalised adult patients
Setiawan, Eko, Cotta, Menino Osbert, Abdul-Aziz, Mohd-Hafiz, Widjanarko, Doddy, Sosilya, Hernycane, Lukas, Dwi Lily, Wallis, Steven C., Parker, Suzanne and Roberts, Jason A. (2023). Population pharmacokinetics and dosing simulations of ampicillin and sulbactam in hospitalised adult patients. Clinical Pharmacokinetics, 62 (4), 1-14. doi: 10.1007/s40262-023-01219-5
2023
Journal Article
Fingerprick microsampling methods can replace venepuncture for simultaneous therapeutic drug monitoring of tacrolimus, mycophenolic acid, and prednisolone concentrations in adult kidney transplant patients
Scuderi, Carla, Parker, Suzanne, Jacks, Margaret, John, George T., McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew, Healy, Helen, Roberts, Jason and Staatz, Christine (2023). Fingerprick microsampling methods can replace venepuncture for simultaneous therapeutic drug monitoring of tacrolimus, mycophenolic acid, and prednisolone concentrations in adult kidney transplant patients. Therapeutic Drug Monitoring, 45 (1), 69-78. doi: 10.1097/FTD.0000000000001024
2022
Conference Publication
Tacrolimus, mycophenolate and prednisolone concentration monitoring using microsampling instead of venepuncture in kidney transplant patients
Scuderi, C. E., Parker, S. L., Jacks, M., John, G. T., McWhinney, B., Ungerer, J., Mallett, A. J., Healy, H. G., Roberts, J. A. and Staatz, C. E. (2022). Tacrolimus, mycophenolate and prednisolone concentration monitoring using microsampling instead of venepuncture in kidney transplant patients. Society of Hospital Pharmacists of Australia, Brisbane, QLD, Australia, 1-3 December 2022.
2022
Journal Article
Optimisation of treatments for oral Neisseria gonorrhoeae infection: Pharmacokinetics Study (STI-PK project) - study protocol for non-randomised clinical trial
Kong, Fabian Y. S., Unemo, Magnus, Lim, Shueh H., Latch, Ngaire, Williamson, Deborah A., Roberts, Jason A., Wallis, Steven C., Parker, Suzanne L., Landersdorfer, Cornelia B., Yap, Tami, Fairley, Christopher K., Chow, Eric P F, Lewis, David A., Hammoud, Mohamed A. and Hocking, Jane S. (2022). Optimisation of treatments for oral Neisseria gonorrhoeae infection: Pharmacokinetics Study (STI-PK project) - study protocol for non-randomised clinical trial. BMJ open, 12 (11) e064782, 1-8. doi: 10.1136/bmjopen-2022-064782
Funding
Current funding
Supervision
Availability
- Dr Suzanne Parker is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
How to use antibiotics better in Paediatric Intensive Care using pharmacokinetic principles
Principal Advisor
Other advisors: Professor Jason Roberts, Professor Jeffrey Lipman
-
Doctor Philosophy
Establishing effective antibiotic and sedative dosing in paediatrics with extracorporeal therapies (including extracorporeal membrane oxygenation and renal replacement therapies)
Principal Advisor
Other advisors: Professor Jason Roberts, Honorary Professor Luregn Schlapbach
-
Doctor Philosophy
Discovery and development of an Antibiotic Modulator to Break Antibiotic Resistance in a Mouse Infection Model
Associate Advisor
Other advisors: Professor Mark Walker, Dr Andy Kuo, Dr David De Oliveira, Emeritus Professor Maree Smith
-
Doctor Philosophy
Stability of cephalosporin/b-lactam with b-lactamase inhibitor combinations for use in OPAT and simulation of OPAT-like drug exposures in a Biofilm model to assess the effect on MDR isolates.
Associate Advisor
Other advisors: Dr Fekade Sime, Professor Jason Roberts
Completed supervision
-
2023
Doctor Philosophy
Translating Microsampling Techniques into Improved Antimicrobial Dosing for Critically Ill Children
Principal Advisor
Other advisors: Professor Jason Roberts, Professor Jeffrey Lipman
Media
Enquiries
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