Overview
Availability
- Honorary Professor Luregn Schlapbach is:
- Available for supervision
Works
Search Professor Luregn Schlapbach’s works on UQ eSpace
2024
Journal Article
The impact of extracorporeal support on antimicrobial pharmacokinetics in critically ill neonatal and paediatric patients: a systematic review
Cree, Michele L., Abdul-Aziz, Mohd Hafiz, Schlapbach, Luregn J., Roberts, Jason A. and Parker, Suzanne (2024). The impact of extracorporeal support on antimicrobial pharmacokinetics in critically ill neonatal and paediatric patients: a systematic review. International Journal of Antimicrobial Agents, 64 (4) 107311, 1-16. doi: 10.1016/j.ijantimicag.2024.107311
2024
Journal Article
Susceptibility to childhood sepsis, contemporary management, and future directions
Carter, Michael J., Carrol, Enitan D., Ranjit, Suchitra, Mozun, Rebeca, Kissoon, Niranjan, Watson, R. Scott and Schlapbach, Luregn J. (2024). Susceptibility to childhood sepsis, contemporary management, and future directions. The Lancet Child and Adolescent Health, 8 (9), 682-694. doi: 10.1016/S2352-4642(24)00141-X
2024
Journal Article
Quality improvement programmes in paediatric sepsis from a global perspective
de Souza, Daniela C., Paul, Raina, Mozun, Rebeca, Sankar, Jhuma, Jabornisky, Roberto, Lim, Emma, Harley, Amanda, Al Amri, Samirah, Aljuaid, Maha, Qian, Suyun, Schlapbach, Luregn J., Argent, Andrew and Kissoon, Niranjan (2024). Quality improvement programmes in paediatric sepsis from a global perspective. The Lancet Child and Adolescent Health, 8 (9), 695-706. doi: 10.1016/S2352-4642(24)00142-1
2024
Journal Article
Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world
Sanchez-Pinto, L Nelson, del Pilar Arias López, María, Scott, Halden, Gibbons, Kristen, Moor, Michael, Watson, R Scott, Wiens, Matthew O, Schlapbach, Luregn J and Bennett, Tellen D (2024). Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world. The Lancet Digital Health, 6 (9), e651-e661. doi: 10.1016/s2589-7500(24)00141-9
2024
Journal Article
The authors reply:
Raman, Sainath, Gibbons, Kristen, LeMarsney, Renate and Schlapbach, Luregn J. (2024). The authors reply:. Pediatric Critical Care Medicine, 25 (9), e398-e399. doi: 10.1097/pcc.0000000000003578
2024
Journal Article
The burden and contemporary epidemiology of sepsis in children
Watson, R. Scott, Carrol, Enitan D., Carter, Michael J., Kissoon, Niranjan, Ranjit, Suchitra and Schlapbach, Luregn J. (2024). The burden and contemporary epidemiology of sepsis in children. The Lancet Child and Adolescent Health, 8 (9), 670-681. doi: 10.1016/S2352-4642(24)00140-8
2024
Journal Article
Sex differences in pediatric sepsis—a systematic review protocol
Kennedy, Uchenna, Moulin, Juliette, Schlapbach, Luregn J., Menon, Kusum, Lee, Jan Hau and Held, Ulrike (2024). Sex differences in pediatric sepsis—a systematic review protocol. Systematic Reviews, 13 (1) 214, 1-5. doi: 10.1186/s13643-024-02631-z
2024
Journal Article
Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomes
Wen, Sophie C.H., Harris, Patrick N. A., Forde, Brian, Permana, Budi, Chatfield, Mark D., Lau, Colleen L., Spurling, Geoffrey, Bauer, Michelle J., Balch, Ross, Chambers, Henry, Schlapbach, Luregn J., Clark, Julia E., Dougherty, Sonia, Blyth, Christopher C., Britton, Philip N., Clifford, Vanessa, Haeusler, Gabrielle M., McMullan, Brendan, Wadia, Ushma, Paterson, David L., Irwin, Adam D., on behalf of the PAEDS network, Carr, Jeremy, Vasilunas, Nan, Francis, Joshua R., Macartney, Kristine, Crawford, Nigel W., Wood, Nicholas, Buttery, Jim ... Glover, Catherine (2024). Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomes. Clinical Infectious Diseases, 79 (3), 734-743. doi: 10.1093/cid/ciae341
2024
Journal Article
Antibiotic Exposure of Critically Ill Children at a Tertiary Care Paediatric Intensive Care Unit in Switzerland
Fenner, Anica, Huber, Melanie, Gotta, Verena, Jaeggi, Vera, Schlapbach, Luregn J. and Baumann, Philipp (2024). Antibiotic Exposure of Critically Ill Children at a Tertiary Care Paediatric Intensive Care Unit in Switzerland. Children, 11 (6) 731, 731. doi: 10.3390/children11060731
2024
Journal Article
The Quest for Evidence on Time to Antibiotics in Children With Sepsis—Finding the Sweet Spot
Luethi, Nora, Schlapbach, Luregn J. and Baumann, Philipp (2024). The Quest for Evidence on Time to Antibiotics in Children With Sepsis—Finding the Sweet Spot. JAMA Network Open, 7 (6) ARTN e2413926, e2413926. doi: 10.1001/jamanetworkopen.2024.13926
2024
Journal Article
Pediatric Phoenix Sepsis Score validation challenges in low-resource settings and in the ED—Reply
Watson, R. Scott, Schlapbach, Luregn J., Sorce, Lauren R. and for the Society of Critical Care Medicine Pediatric Sepsis Definitions Task Force (2024). Pediatric Phoenix Sepsis Score validation challenges in low-resource settings and in the ED—Reply. JAMA, 331 (24), E1-E1. doi: 10.1001/jama.2024.8447
2024
Journal Article
Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study
Schlapbach, Luregn J., Ganesamoorthy, Devika, Wilson, Clare, Raman, Sainath, George, Shane, Snelling, Peter J., Phillips, Natalie, Irwin, Adam, Sharp, Natalie, Le Marsney, Renate, Chavan, Arjun, Hempenstall, Allison, Bialasiewicz, Seweryn, MacDonald, Anna D., Grimwood, Keith, Cling, Jessica C., McPherson, Stephen J., Blumenthal, Antje, Kaforou, Myrsini, Levin, Michael, Herberg, Jethro A., Gibbons, Kristen S., Coin, Lachlan J. M., EUCLIDS consortium and RAPIDS Study Group (2024). Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study. The Lancet Child and Adolescent Health, 8 (5), 325-338. doi: 10.1016/S2352-4642(24)00017-8
2024
Journal Article
Swissped-RECOVERY: masked independent adjudication for the interpretation of non-randomised treatment in a two-arm open-label randomised controlled trial (methylprednisolone vs immunoglobulins) in Paediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS) involving 10 secondary and tertiary paediatric hospitals in Switzerland
Schöbi, Nina, Sanchez, Carlos, Welzel, Tatjana, Bamford, Alasdair, Webb, Kate, Rojo, Pablo, Tremoulet, Adriana, Atkinson, Andrew, Schlapbach, Luregn J. and Bielicki, Julia Anna (2024). Swissped-RECOVERY: masked independent adjudication for the interpretation of non-randomised treatment in a two-arm open-label randomised controlled trial (methylprednisolone vs immunoglobulins) in Paediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS) involving 10 secondary and tertiary paediatric hospitals in Switzerland. BMJ open, 14 (4) e078137, e078137. doi: 10.1136/bmjopen-2023-078137
2024
Journal Article
Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis
Khan, Nemat, Kumar, Vinod, Li, Pengcheng, RAPIDS Study Group, Raman, Sainath (RSG member), Sharp, Natalie (RSG member), Irwin, Adam (RSG member), Phillips, Natalie (RSG member), George, Shane (RSG member), Grimwood, Keith (RSG member), Snelling, Peter (RSG member), Chavan, Arjun (RSG member), Hempenstall, Allison (RSG member), Gibbons, Kristen (RSG member), Le Marsney, Renate (RSG member), Blumenthal, Antje (RSG member), Ganesamoorthy, Devika (RSG member), Coin, Lachlan (RSG member), Schlapbach, Luregn J., Boyd, Andrew W., Coulthard, Mark G. and Woodruff, Trent M. (2024). Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis. Science Translational Medicine, 16 (744) eadg5768, 1-15. doi: 10.1126/scitranslmed.adg5768
2024
Journal Article
A Critique of the “Conservative Versus Liberal Oxygenation Targets in Critically Ill Children” Multicenter, Randomized Clinical Trial Published in the Lancet 2024—More on “Less Is More?”
Mozun, Rebeca and Schlapbach, Luregn J. (2024). A Critique of the “Conservative Versus Liberal Oxygenation Targets in Critically Ill Children” Multicenter, Randomized Clinical Trial Published in the Lancet 2024—More on “Less Is More?”. Pediatric Critical Care Medicine, 25 (7), e338-e342. doi: 10.1097/pcc.0000000000003519
2024
Journal Article
Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis
Chai, Ming G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., Mcwhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (5), 810-810. doi: 10.1007/s00134-024-07393-9
2024
Journal Article
Platelet reactivity in young children undergoing congenital heart disease surgery: a NITRIC randomized clinical trial substudy
van Loon, Kim, Koomen, Erik, Hiensch, Senna, van Belle- van Haaren, Nicole J. C. W., Koelhuis-Faber, Mizja, Charlier, Jean-Luc, Lammers, Jan, Imhof, Oscar, Nijman, Joppe, van Wijk, Abraham, Breur, Johannes M. P. J., Gibbons, Kristen, Butt, Warwick, Schlapbach, Luregn J., Horton, Stephen, Korporaal, Suzanne and the NITRIC Study Group (2024). Platelet reactivity in young children undergoing congenital heart disease surgery: a NITRIC randomized clinical trial substudy. Intensive Care Medicine – Paediatric and Neonatal, 2 (1) 13. doi: 10.1007/s44253-024-00037-2
2024
Journal Article
Raising AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care: results from the PERFORM study assessing consistency and appropriateness of antibiotic prescribing across Europe
Kolberg, Laura, Khanijau, Aakash, van der Velden, Fabian J S, Herberg, Jethro, De, Tisham, Galassini, Rachel, Cunnington, Aubrey J, Wright, Victoria, Shah, Priyen, Kaforou, Myrsini, Wilson, Clare, Kuijpers, Taco, Martinón-Torres, Federico, Rivero-Calle, Irene, Moll, Henriette, Vermont, Clementien, Pokorn, Marko, Kolnik, Mojca, Pollard, Andrew J, Agyeman, Philipp K A, Schlapbach, Luregn J, Tsolia, Maria N, Yeung, Shunmay, Zavadska, Dace, Zenz, Werner, Schweintzger, Nina A, van der Flier, Michiel, de Groot, Ronald, Usuf, Effua ... The PERFORM Consortium (2024). Raising AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care: results from the PERFORM study assessing consistency and appropriateness of antibiotic prescribing across Europe. Clinical Infectious Diseases, 78 (3), 526-534. doi: 10.1093/cid/ciad615
2024
Journal Article
Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis
Chai, Gene G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., McWhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (4), 1-9. doi: 10.1007/s00134-024-07353-3
2024
Journal Article
Intravenous maintenance fluid therapy in acutely and critically ill children: state of the evidence
Brossier, David W., Goyer, Isabelle, Verbruggen, Sascha C. A. T., Jotterand Chaparro, Corinne, Rooze, Shancy, Marino, Luise V., Schlapbach, Luregn J., Tume, Lyvonne N. and Valla, Frederic V. (2024). Intravenous maintenance fluid therapy in acutely and critically ill children: state of the evidence. The Lancet Child and Adolescent Health, 8 (3), 236-244. doi: 10.1016/s2352-4642(23)00288-2
Funding
Current funding
Supervision
Availability
- Honorary Professor Luregn Schlapbach is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Improving drug therapy for children with sepsis and life-threatening infections
Associate Advisor
Other advisors: Dr Sainath Raman, Professor Jason Roberts
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Doctor Philosophy
Establishing effective antibiotic and sedative dosing in paediatrics with extracorporeal therapies (including extracorporeal membrane oxygenation and renal replacement therapies)
Associate Advisor
Other advisors: Professor Jason Roberts, Dr Suzanne Parker
Completed supervision
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2022
Doctor Philosophy
Recognition, Escalation, and Management of Paediatric Sepsis in the Emergency Department
Associate Advisor
Other advisors: Dr Amy Johnston
Media
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