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Dr Sainath Raman
Dr

Sainath Raman

Email: 

Overview

Availability

Dr Sainath Raman is:
Available for supervision
Media expert

Research interests

  • Paediatric Sepsis

    Early Diagnostics Therapeutic Interventions Long term outcome

  • Paediatric Critical Illness

    Common interventions in intensive care - Oxygen and intravenous fluid therapy

Works

Search Professor Sainath Raman’s works on UQ eSpace

54 works between 2009 and 2024

1 - 20 of 54 works

2024

Journal Article

Recommendations for the College of Intensive Care Medicine (CICM) trainee research project: A modified Delphi study

Ho, Ariel, Denny, Kerina J., Laupland, Kevin B., Ramanan, Mahesh, Tabah, Alexis, McCullough, James, Schults, Jessica A., Raman, Sainath, Apte, Yogesh, Attokaran, Antony, Baker, Stuart, Bartholdy, Roland, Bhadange, Neeraj, Brailsford, Jane, Cook, Katrina, David, Alexandre, Dhanani, Jayesh, Edwards, Felicity, Elkady, Hatem, Evans, Tess, Hutchinson, Jane, Lannon, Sean, Marshall, Andrea, McIlroy, Philippa, Milford, Elissa, Morrison, Lynette, Murray, Lauren, Serratore, Alyssa, Shah, Vikram ... White, Kyle (2024). Recommendations for the College of Intensive Care Medicine (CICM) trainee research project: A modified Delphi study. Critical Care and Resuscitation. doi: 10.1016/j.ccrj.2024.05.002

Recommendations for the College of Intensive Care Medicine (CICM) trainee research project: A modified Delphi study

2024

Journal Article

Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study

Schlapbach, Luregn J., Ganesamoorthy, Devika, Wilson, Clare, Raman, Sainath, George, Shane, Snelling, Peter J., Phillips, Natalie, Irwin, Adam, Sharp, Natalie, Le Marsney, Renate, Chavan, Arjun, Hempenstall, Allison, Bialasiewicz, Seweryn, MacDonald, Anna D., Grimwood, Keith, Cling, Jessica C., McPherson, Stephen J., Blumenthal, Antje, Kaforou, Myrsini, Levin, Michael, Herberg, Jethro A., Gibbons, Kristen S., Coin, Lachlan J. M., EUCLIDS consortium and RAPIDS Study Group (2024). Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study. The Lancet Child and Adolescent Health, 8 (5), 325-338. doi: 10.1016/S2352-4642(24)00017-8

Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study

2024

Journal Article

Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis

Khan, Nemat, Kumar, Vinod, Li, Pengcheng, RAPIDS Study Group, Raman, Sainath (RSG member), Sharp, Natalie (RSG member), Irwin, Adam (RSG member), Phillips, Natalie (RSG member), George, Shane (RSG member), Grimwood, Keith (RSG member), Snelling, Peter (RSG member), Chavan, Arjun (RSG member), Hempenstall, Allison (RSG member), Gibbons, Kristen (RSG member), Le Marsney, Renate (RSG member), Blumenthal, Antje (RSG member), Ganesamoorthy, Devika (RSG member), Coin, Lachlan (RSG member), Schlapbach, Luregn J., Boyd, Andrew W., Coulthard, Mark G. and Woodruff, Trent M. (2024). Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis. Science Translational Medicine, 16 (744) eadg5768, 1-15. doi: 10.1126/scitranslmed.adg5768

Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis

2024

Journal Article

Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis

Chai, Ming G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., Mcwhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (5), 810-810. doi: 10.1007/s00134-024-07393-9

Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis

2024

Journal Article

Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis

Chai, Gene G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., McWhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (4), 1-9. doi: 10.1007/s00134-024-07353-3

Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis

2024

Journal Article

Resuscitation with early adrenaline infusion for children with septic shock: a randomized pilot trial

Harley, Amanda, George, Shane, Phillips, Natalie, King, Megan, Long, Debbie, Keijzers, Gerben, Lister, Paula, Raman, Sainath, Bellomo, Rinaldo, Gibbons, Kristen, Schlapbach, Luregn J. and on behalf of Resuscitation in Paediatric Sepsis Randomized Controlled Pilot Platform Study in the Emergency Department (RESPOND ED) Study Group (2024). Resuscitation with early adrenaline infusion for children with septic shock: a randomized pilot trial. Pediatric Critical Care Medicine, 25 (2), 106-117. doi: 10.1097/PCC.0000000000003351

Resuscitation with early adrenaline infusion for children with septic shock: a randomized pilot trial

2024

Journal Article

Resuscitation with vitamin C, hydrocortisone, and thiamin in children with septic shock: a multicenter randomized pilot study

Schlapbach, Luregn J., Raman, Sainath, Buckley, David, George, Shane, King, Megan, Ridolfi, Roberta, Harley, Amanda, Cree, Michele, Long, Debbie, Erickson, Simon, Singh, Puneet, Festa, Marino, Gibbons, Kristen, Bellomo, Rinaldo and on behalf of Resuscitation in Paediatric Sepsis Randomized Controlled Pilot Platform in the Paediatric Intensive Care Unit (RESPOND PICU) Study Investigators and the Australian and New Zealand Intensive Care Society Paediatric Study Group (2024). Resuscitation with vitamin C, hydrocortisone, and thiamin in children with septic shock: a multicenter randomized pilot study. Pediatric Critical Care Medicine, 25 (2), 159-170. doi: 10.1097/PCC.0000000000003346

Resuscitation with vitamin C, hydrocortisone, and thiamin in children with septic shock: a multicenter randomized pilot study

2024

Journal Article

Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort study

McWhinney, Brett, Ungerer, Jacobus, LeMarsey, Renate, Phillips, Natalie, Raman, Sainath, Gibbons, Kristen, Schlapbach, Luregn J., on behalf of Rapid Acute Paediatric Infection Diagnosis in Suspected Sepsis (RAPIDS) Study Investigators and Irwin, Adam (RAPIDS member) (2024). Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort study. Pediatric Critical Care Medicine, 25 (2), 171-176. doi: 10.1097/PCC.0000000000003349

Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort study

2024

Journal Article

Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis

Harris, Patrick N. A., Bauer, Michelle J., Lüftinger, Lukas, Beisken, Stephan, Forde, Brian M., Balch, Ross, Cotta, Menino, Schlapbach, Luregn, Raman, Sainath, Shekar, Kiran, Kruger, Peter, Lipman, Jeff, Bialasiewicz, Seweryn, Coin, Lachlan, Roberts, Jason A., Paterson, David L. and Irwin, Adam D. (2024). Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis. Microbiology spectrum, 12 (2) e0306523, e0306523. doi: 10.1128/spectrum.03065-23

Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis

2024

Conference Publication

Extensively hydrolysed formula improves nutritional outcomes and decreases gut complication risk in infants with complex congenital heart disease

Woodgate, Jemma, Raman, Sainath, McBride, Craig, Marathe, Supreet, Ward, Cameron, Gillman, Nicholas and Joshi, Vineet (2024). Extensively hydrolysed formula improves nutritional outcomes and decreases gut complication risk in infants with complex congenital heart disease. Australian and New Zealand Intensive Care Society/Australian College of Critical Care Nursing Intensive Care Annual Scientific meeting, Brisbane, QLD Australia, 10-12 April 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2024.07.050

Extensively hydrolysed formula improves nutritional outcomes and decreases gut complication risk in infants with complex congenital heart disease

2024

Conference Publication

The fusion study – Compatibility of antibiotics with commonly used medication infusions in a paediatric intensive care unit

Tu, Quyen, Won, Hayoung Helen, Sime, Fekade, Wallis, Steven, Raman, Sainath, Stacey, Sonya, Cotta, Menino, Schlapbach, Luregn and Roberts, Jason (2024). The fusion study – Compatibility of antibiotics with commonly used medication infusions in a paediatric intensive care unit. Australian and New Zealand Intensive Care Society/Australian College of Critical Care Nursing Intensive Care Annual Scientific meeting, Brisbane, QLD Australia, 10-12 April 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2024.07.037

The fusion study – Compatibility of antibiotics with commonly used medication infusions in a paediatric intensive care unit

2023

Journal Article

Implementing paediatric appropriate use criteria for endotracheal suction to reduce complications in mechanically ventilated children with respiratory infections

Schults, Jessica A., Charles, Karina R., Harnischfeger, Jane, Ware, Robert S., Royle, Ruth H., Byrnes, Joshua M., Long, Debbie A., Ullman, Amanda J., Raman, Sainath, Waak, Michaela, Lake, Anna, Cooke, Marie, Irwin, Adam, Tume, Lyvonne and Hall, Lisa (2023). Implementing paediatric appropriate use criteria for endotracheal suction to reduce complications in mechanically ventilated children with respiratory infections. Australian Critical Care, 37 (1), 1-9. doi: 10.1016/j.aucc.2023.09.008

Implementing paediatric appropriate use criteria for endotracheal suction to reduce complications in mechanically ventilated children with respiratory infections

2023

Journal Article

Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis

Obonyo, Nchafatso G., Sela, Declan P., Raman, Sainath, Rachakonda, Reema, Schneider, Bailey, Hoe, Louise E. See, Fanning, Jonathon P., Bassi, Gianluigi Li, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2023). Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis. Systematic Reviews, 12 (1) 221, 1-17. doi: 10.1186/s13643-023-02385-0

Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis

2023

Journal Article

REstrictive versus StandarD FlUid Management in Mechanically Ventilated ChildrEn Admitted to PICU: study protocol for a pilot randomised controlled trial (REDUCE-1)

Raman, Sainath, Rahiman, Sarfaraz, Kennedy, Melanie, Mattke, Adrian, Venugopal, Prem, McBride, Craig, Tu, Quyen, Zapf, Florian, Kuhlwein, Eva, Woodgate, Jemma, Singh, Puneet, Schlapbach, Luregn J. and Gibbons, Kristen S. (2023). REstrictive versus StandarD FlUid Management in Mechanically Ventilated ChildrEn Admitted to PICU: study protocol for a pilot randomised controlled trial (REDUCE-1). BMJ Open, 13 (11) e076460, 1-8. doi: 10.1136/bmjopen-2023-076460

REstrictive versus StandarD FlUid Management in Mechanically Ventilated ChildrEn Admitted to PICU: study protocol for a pilot randomised controlled trial (REDUCE-1)

2023

Journal Article

Adaptive clinical trials in pediatric critical care: a systematic review

Gilholm, Patricia, Ergetu, Endrias, Gelbart, Ben, Raman, Sainath, Festa, Marino, Schlapbach, Luregn J., Long, Debbie, Gibbons, Kristen S. and on behalf of the Australian and New Zealand Intensive Care Society Paediatric Study Group (2023). Adaptive clinical trials in pediatric critical care: a systematic review. Pediatric Critical Care Medicine, 24 (9), 738-749. doi: 10.1097/pcc.0000000000003273

Adaptive clinical trials in pediatric critical care: a systematic review

2023

Journal Article

Longitudinal cohort study investigating neurodevelopmental and socioemotional outcomes in school-entry aged children after open heart surgery in Australia and New Zealand: the NITRIC follow-up study protocol

Long, Debbie, Anderson, Vicki A., Crossley, Louise, Sood, Nikita Tuli, Charles, Karina R., MacDonald, Anna D., Bora, Samudragupta, Pestell, Carmela F., Murrell, Kathryn, Pride, Natalie A., Anderson, Peter J., Badawi, Nadia, Rose, Brian, Baillie, Heidi, Masterson, Kate, Chumbes Flores, Jenipher, Sherring, Claire, Raman, Sainath, Beca, John, Erickson, Simon, Festa, Marino, Anderson, Benjamin W., Venugopal, Prem, Yim, Deane, Andrews, David, Cheung, Michael, Brizard, Christian, Gentles, Thomas L., Iyengar, Ajay ... Gibbons, Kristen S. (2023). Longitudinal cohort study investigating neurodevelopmental and socioemotional outcomes in school-entry aged children after open heart surgery in Australia and New Zealand: the NITRIC follow-up study protocol. BMJ Open, 13 (8) e075429, e075429. doi: 10.1136/bmjopen-2023-075429

Longitudinal cohort study investigating neurodevelopmental and socioemotional outcomes in school-entry aged children after open heart surgery in Australia and New Zealand: the NITRIC follow-up study protocol

2023

Journal Article

Author Correction: Combined effects of sepsis and extracorporeal membrane oxygenation on left ventricular performance in a murine model

Kayumov, Mukhammad, Kim, Dowan, Raman, Sainath, MacLaren, Graeme, Jeong, In Seok and Cho, Hwa Jin (2023). Author Correction: Combined effects of sepsis and extracorporeal membrane oxygenation on left ventricular performance in a murine model. Scientific Reports, 13 (1) 1049, 1-1. doi: 10.1038/s41598-023-28375-9

Author Correction: Combined effects of sepsis and extracorporeal membrane oxygenation on left ventricular performance in a murine model

2023

Journal Article

Resuscitation Associated Endotheliopathy (PubMed)

Obonyo, Nchafatso G., Sela, Declan P., Raman, Sainath, Rachakonda, Reema, Schneider, Bailey, Hoe, Louise E. See, Fanning, Jonathon P., Bassi, Gianluigi Li, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2023). Resuscitation Associated Endotheliopathy (PubMed). searchRxiv, 2023. doi: 10.1079/searchrxiv.2023.00206

Resuscitation Associated Endotheliopathy (PubMed)

2023

Journal Article

Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia

Gilholm, Patricia, Gibbons, Kristen, Lister, Paula, Harley, Amanda, Irwin, Adam, Raman, Sainath, Rice, Michael, Schlapbach, Luregn J. and Queensland Statewide Sepsis Collaborative (2023). Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia. BMJ Open, 13 (1) e061431, 1-25. doi: 10.1136/bmjopen-2022-061431

Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia

2022

Journal Article

Effect of Saline vs gluconate/acetate–buffered solution vs lactate-buffered solution on serum chloride among children in the pediatric Intensive Care Unit: the SPLYT-P randomized clinical trial

Raman, Sainath, Gibbons, Kristen S., Mattke, Adrian, Schibler, Andreas, Trnka, Peter, Kennedy, Melanie, Le Marsney, Renate and Schlapbach, Luregn J. (2022). Effect of Saline vs gluconate/acetate–buffered solution vs lactate-buffered solution on serum chloride among children in the pediatric Intensive Care Unit: the SPLYT-P randomized clinical trial. JAMA Pediatrics, 177 (2), 122-131. doi: 10.1001/jamapediatrics.2022.4912

Effect of Saline vs gluconate/acetate–buffered solution vs lactate-buffered solution on serum chloride among children in the pediatric Intensive Care Unit: the SPLYT-P randomized clinical trial

Funding

Current funding

  • 2023 - 2025
    Building together: Better consenting practices for the most vulnerable in healthcare research
    Metro South Research Support Scheme Co-funded Collaboration Grant
    Open grant
  • 2022 - 2027
    Resuscitation in Paediatric Septic Shock using Mega-Dose Vitamin C and Hydrocortisone - A Randomised Controlled Multicentre Trial (RESPOND study)
    NHMRC Clinical Trials and Cohort Studies Grants
    Open grant

Past funding

  • 2022 - 2024
    Resuscitation in Paediatric Septic Shock using Mega-Dose Vitamin C and Hydrocortisone - A Randomised Controlled Multicentre Trial (RESPOND study)
    Preclinical and Clinical Early Career Research
    Open grant
  • 2021 - 2022
    Preventing healthcare acquired, ventilator- associated conditions in the PICU: Implementation of new airway clearance guidance
    The Children's Hospital Foundation
    Open grant
  • 2021 - 2023
    Restrictive Fluid Strategy vs Standard Care in Mechanically Ventilated Children - a Feasibility Pilot Randomised Controlled Trial
    Preclinical and Clinical Early Career Research
    Open grant
  • 2020 - 2021
    Acute Resuscitation In Paediatric Sepsis (ARISE-KIDS) - a randomised controlled trail to reduce morbidity and mortality due to sepsis in children
    The Children's Hospital Foundation
    Open grant
  • 2020 - 2024
    Host Gene Expression Signatures to Diagnose Sepsis in Children
    MRFF Genomics Health Futures Mission, Project Grant administered by AusIndustry
    Open grant

Supervision

Availability

Dr Sainath Raman is:
Available for supervision

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Supervision history

Current supervision

Media

Enquiries

Contact Dr Sainath Raman directly for media enquiries about:

  • Paediatric Critical Illness
  • Paediatric Sepsis

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