Overview
Background
I completed my PhD in the Molecular and Cellular Biology Program at the Federal University of Parana (UFPR – Curitiba, Brazil). My PhD research focused on developing new treatments based on chemically modified heparins for preventing melanoma metastatic spread in different experimental models. During my PhD, I also performed an international exchange with Prof. Nicholas Huntington and Dr. Fernando Guimaraes at the Walter and Eliza Hall Institute (WEHI, Melbourne) to elucidate the mechanisms of how these new compounds can impact innate immunity, particularly in activation of natural killer (NK) cells. My current postdoctoral interests at the Translational Innate Immunotherapy Laboratory (TI2) at UQDI focuses on understanding the impact of tumour microenvironment (TME)-mediated regulation of NK cell tumoricidal immunity, and how to take advantage of this new knowledge to model and develop new immune-cellular interventions to fight cancer. My projects now take advantage of multi-disciplinary approaches combining cutting edge molecular/immune/stem cell biology and systems biology to build on and create innovative solutions for complex clinical challenges.
Availability
- Dr Gustavo Rodrigues Rossi is:
- Available for supervision
Qualifications
- Doctor of Philosophy, unknown
Works
Search Professor Gustavo Rodrigues Rossi’s works on UQ eSpace
2020
Journal Article
Tumor microenvironment-associated extracellular matrix components regulate NK cell function
Rossi, Gustavo Rodrigues, Trindade, Edvaldo S. and Souza-Fonseca-Guimaraes, Fernando (2020). Tumor microenvironment-associated extracellular matrix components regulate NK cell function. Frontiers in Immunology, 11 73, 73. doi: 10.3389/fimmu.2020.00073
2020
Journal Article
Non-cytotoxic sulfated heterorhamnan from Gayralia brasiliensis green seaweed reduces driver features of melanoma metastatic progression
Bellan, D. L., Mazepa, E., Biscaia, S. M. P., Gonçalves, J. P., Oliveira, C. C., Rossi, G. R., Ferreira, L. G., Noseda, M. D., Trindade, E. S., Duarte, M. E. R. and Franco, C. R. C. (2020). Non-cytotoxic sulfated heterorhamnan from Gayralia brasiliensis green seaweed reduces driver features of melanoma metastatic progression. Marine Biotechnology, 22 (2), 194-206. doi: 10.1007/s10126-020-09944-9
2019
Journal Article
Preparation and characterization of 4-nitrochalcone-folic acid-poly(methyl methacrylate) nanocapsules and cytotoxic activity on HeLa and NIH3T3 cells
Carpio Arévalo, Juan Marcelo, Feuser, Paulo Emilio, Rossi, Gustavo Rodrigues, Trindade, Edvaldo S., da Silva Córneo, Emily, Machado-de-Ávila, Ricardo Andrez, Sayer, Claudia, Cadena, Silvia Maria Suter C., Noleto, Guilhermina Rodrigues, Martinez, Glaucia Regina, Hermes de Araújo, Pedro H. and Merlin Rocha, Maria Eliane (2019). Preparation and characterization of 4-nitrochalcone-folic acid-poly(methyl methacrylate) nanocapsules and cytotoxic activity on HeLa and NIH3T3 cells. Journal of Drug Delivery Science and Technology, 54 101300, 101300. doi: 10.1016/j.jddst.2019.101300
2019
Journal Article
Microscopic analysis of colonization of Colletotrichum abscissum in citrus tissues
Savi, Daiani Cristina, Rossi, Bruno Janoski, Rossi, Gustavo Rodrigues, Ferreira-Maba, Lisandra Santos, Bini, Israel Henrique, Trindade, Edvaldo da Silva, Goulin, Eduardo Henrique, Machado, Marcos Antonio and Glienke, Chirlei (2019). Microscopic analysis of colonization of Colletotrichum abscissum in citrus tissues. Microbiological Research, 226, 27-33. doi: 10.1016/j.micres.2019.05.005
2019
Journal Article
Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β
Healy, Lachlan P., Rossi, Gustavo R., Rautela, Jai, Slade, Charlotte A., Huntington, Nicholas D., Winship, Ingrid M. and Souza-Fonseca-Guimaraes, Fernando (2019). Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β. Frontiers in Immunology, 10 (MAY) 904. doi: 10.3389/fimmu.2019.00904
2019
Journal Article
Viscera of fishes as raw material for extraction of glycosaminoglycans of pharmacological interest
Nogueira, Alexsandro V., Rossi, Gustavo R., Iacomini, Marcello, Sassaki, Guilherme L., Trindade, Edvaldo S. and Cipriani, Thales R. (2019). Viscera of fishes as raw material for extraction of glycosaminoglycans of pharmacological interest. International Journal of Biological Macromolecules, 121, 239-248. doi: 10.1016/j.ijbiomac.2018.09.156
2019
Journal Article
In vitro attenuation of classic metastatic melanoma-related features by highly diluted natural complexes: molecular and functional analyses
Gonçalves, Jenifer Pendiuk, Potrich, Francine Bittencourt, Dos Santos, Maria Luiza Ferreira, Gagosian, Viviana Stephanie Costa, Rossi, Gustavo Rodrigues, Thiago, Jacomasso, Mendes, Aline, Nader, Helena Bonciani, Winnischofer, Sheila Maria Brochado, Trindade, Edvaldo S. and De Oliveira, Carolina Camargo (2019). In vitro attenuation of classic metastatic melanoma-related features by highly diluted natural complexes: molecular and functional analyses. International Journal of Oncology, 55 (3), 721-732. doi: 10.3892/ijo.2019.4846
2018
Journal Article
Monoclonal antibody DL11C8 identifies ADAM23 as a component of lipid raft microdomains
Borgonovo, Zaine L. M., Ribeiro, Caroline F., Costa, Michele D. M., Souza, Ingrid L. M., Rossi, Gustavo R., Alcantara, Monica V., Ingberman, Max, Braga, Luciano G., Mercadante, Adriana F., Nakao, Lia S. and Zanata, Silvio M. (2018). Monoclonal antibody DL11C8 identifies ADAM23 as a component of lipid raft microdomains. Neuroscience, 384, 165-177. doi: 10.1016/j.neuroscience.2018.05.016
2018
Journal Article
A low-molecular-weight galactofucan from the seaweed, Spatoglossum schröederi, binds fibronectin and inhibits capillary-like tube formation in vitro
Menezes, Maira Maria, Nobre, Leonardo Thiago Duarte Barreto, Rossi, Gustavo Rodrigues, Almeida-Lima, Jailma, Melo-Silveira, Raniere Fagundes, Franco, Celia Regina Cavichiolo, Trindade, Edvaldo Silva, Nader, Helena Bonciani and Rocha, Hugo Alexandre Oliveira (2018). A low-molecular-weight galactofucan from the seaweed, Spatoglossum schröederi, binds fibronectin and inhibits capillary-like tube formation in vitro. International Journal of Biological Macromolecules, 111, 1067-1075. doi: 10.1016/j.ijbiomac.2018.01.119
2017
Journal Article
Safe therapeutics of murine melanoma model using a novel antineoplasic, the partially methylated mannogalactan from Pleurotus eryngii
Biscaia, S. M.P., Carbonero, E. R., Bellan, D. L., Borges, B. S., Costa, C. R., Rossi, G. R., Gonçalves, J. P., Melo, C. M., Lívero, F. A.R., Ruthes, A. C., Zotz, R., Silva, E. V., Oliveira, C. C., Acco, A., Nader, H. B., Chammas, R., Iacomini, M., Franco, C. R.C. and Trindade, E. S. (2017). Safe therapeutics of murine melanoma model using a novel antineoplasic, the partially methylated mannogalactan from Pleurotus eryngii. Carbohydrate Polymers, 178, 95-104. doi: 10.1016/j.carbpol.2017.08.117
2016
Journal Article
Increased cellular uptake of lauryl gallate loaded in superparamagnetic poly(methyl methacrylate) nanoparticles due to surface modification with folic acid
Feuser, Paulo Emilio, Arévalo, Juan Marcelo Carpio, Junior, Enio Lima, Rossi, Gustavo Rodrigues, da Silva Trindade, Edvaldo, Rocha, Maria Eliane Merlin, Jacques, Amanda Virtuoso, Ricci-Júnior, Eduardo, Santos-Silva, Maria Claudia, Sayer, Claudia and de Araújo, Pedro H. Hermes (2016). Increased cellular uptake of lauryl gallate loaded in superparamagnetic poly(methyl methacrylate) nanoparticles due to surface modification with folic acid. Journal of Materials Science: Materials in Medicine, 27 (12) 185. doi: 10.1007/s10856-016-5796-0
2015
Journal Article
Effect of pegylated phosphatidylserine-containing liposomes in experimental chronic arthritis
Urbano, Paulo C.M., Soccol, Vanete T., Teixeira, Vivian N., Oliveira, Patrícia G., Filippin, Lidiane I., Bonat, Wagner H., de Oliveira, Carolina, Rossi, Gustavo R., Xavier, Ricardo M. and Azevedo, Valderilio F. (2015). Effect of pegylated phosphatidylserine-containing liposomes in experimental chronic arthritis. BMC Pharmacology and Toxicology, 16 (1) 24. doi: 10.1186/s40360-015-0022-0
Supervision
Availability
- Dr Gustavo Rodrigues Rossi is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Immune regulation through bi-directional interactions between subsets of Natural Killer cells and Dendritic cells.
Associate Advisor
Other advisors: Professor Andrew Barbour, Dr Arutha Kulasinghe, Dr Camille Guillerey, Associate Professor Fernando Guimaraes
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Doctor Philosophy
Enhancement of natural killer cell function for therapeutic targeting and elimination of metastatic breast cancer
Associate Advisor
Other advisors: Associate Professor Fiona Simpson, Associate Professor Fernando Guimaraes
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Doctor Philosophy
KIR-mismatched NK-cells graft-versus-paediatric sarcoma effect
Associate Advisor
Other advisors: Associate Professor Wayne Nicholls, Associate Professor Fernando Guimaraes
Media
Enquiries
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