Overview
Background
A/Prof Wayne Nicholls is a highly regarded paediatric oncologist who currently holds the position of Director of the Oncology Services Group at Queensland Children’s Hospital. Additionally, he serves as the Clinical Director of the Ian Frazer Centre for Children’s Immunotherapy Research (IFCCIR) at the University of Queensland. A/Prof Nicholls is committed to supporting the translation of research into clinical practice, with a particular emphasis on the treatment of paediatric, adolescent, and young adult (AYA) brain tumours and sarcomas.
He is a strong advocate for the advancement of immunotherapy research and treatment options for children with cancer. Under his leadership at the IFCCIR, efforts are focused on the development of novel and innovative immunotherapies that address the unique challenges associated with high-risk paediatric cancers and other immune-related diseases. His work is driven by a deep commitment to improving outcomes for young patients and their families.
Availability
- Associate Professor Wayne Nicholls is:
- Not available for supervision
Research impacts
Associate Professor Wayne Nicholls has demonstrated exceptional leadership and dedication in the field of paediatric oncology through his extensive involvement in professional organisations including the Clinical Oncology Society of Australia, the Australian and New Zealand Sarcoma Association (ANZSA), and the Clinical Oncology Society of Australia (COSA).
Through his involvement in Queensland Health Steering Committees and as the Paediatric representative for the Statewide Cancer Clinical Network, he has played a pivotal role in shaping policies and advancing research initiatives aimed at improving cancer care for adolescents and young adults. His community engagement efforts, including close collaboration with non-government organizations such as the Children’s Hospital Foundation, Childhood Cancer Support, Richie’s Rainbow Foundation, and the Cooper Rice-Brading Foundation, demonstrate his dedication to translating research findings into tangible benefits for patients and their families.
A/Prof Nicholls has been awarded grant funding from the Medical Research Future Fund, the National Health & Medical Research Council, Tour de Cure, and the Australian and New Zealand Sarcoma Association.
Works
Search Professor Wayne Nicholls’s works on UQ eSpace
2024
Journal Article
Precision-guided treatment in high-risk pediatric cancers
Lau, Loretta M. S., Khuong-Quang, Dong-Anh, Mayoh, Chelsea, Wong, Marie, Barahona, Paulette, Ajuyah, Pamela, Senapati, Akanksha, Nagabushan, Sumanth, Sherstyuk, Alexandra, Altekoester, Ann-Kristin, Fuentes-Bolanos, Noemi A., Yeung, Veronica, Sullivan, Ashleigh, Omer, Natacha, Diamond, Yonatan, Jessop, Sophie, Battaglia, Lauren, Zhukova, Nataliya, Cui, Louise, Lin, Angela, Gifford, Andrew J., Fleuren, Emmy D. G., Dalla-Pozza, Luciano, Moore, Andrew S., Khaw, Seong-Lin, Eisenstat, David D., Gottardo, Nicholas G., Wood, Paul J., Tapp, Heather ... Ziegler, David S. (2024). Precision-guided treatment in high-risk pediatric cancers. Nature Medicine, 30 (7), 1913-1922. doi: 10.1038/s41591-024-03044-0
2023
Journal Article
A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer
Mayoh, Chelsea, Gifford, Andrew J., Terry, Rachael, Lau, Loretta M S, Wong, Marie, Rao, Padmashree, Shai-Hee, Tyler, Saletta, Federica, Khuong-Quang, Dong-Anh, Qin, Vicky, Mateos, Marion K., Meyran, Deborah, Miller, Katherine E., Yuksel, Aysen, Mould, Emily V A, Bowen-James, Rachel, Govender, Dinisha, Senapati, Akanksha, Zhukova, Nataliya, Omer, Natacha, Dholaria, Hetal, Alvaro, Frank, Tapp, Heather, Diamond, Yonatan, Pozza, Luciano Dalla, Moore, Andrew S., Nicholls, Wayne, Gottardo, Nicholas G., McCowage, Geoffrey ... Ekert, Paul G. (2023). A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer. Genome Medicine, 15 (1) 20, 20. doi: 10.1186/s13073-023-01170-x
2023
Journal Article
One Hundred Times Better, at Home in Our Own Beds: Implementation of Home Intravenous Hydration After Chemotherapy in Children With Cancer
Orford, Rebekah, Slater, Penelope, Spencer, Brooke, Giarola, Teghan, Nicholls, Wayne, Walker, Rick, Foresto, Steven and Bradford, Natalie (2023). One Hundred Times Better, at Home in Our Own Beds: Implementation of Home Intravenous Hydration After Chemotherapy in Children With Cancer. Journal of Pediatric Hematology/Oncology Nursing, 40 (4), 265-276. doi: 10.1177/27527530221147880
2022
Journal Article
COVID-19 vaccination in children and adolescents aged 5 years and older undergoing treatment for cancer and non-malignant haematological conditions: Australian and New Zealand Children’s Haematology/Oncology Group consensus statement
Furlong, Eliska, Kotecha, Rishi S, Conyers, Rachel, O'Brien, Tracey A, Hansford, Jordan R, Super, Leanne, Downie, Peter, Eisenstat, David D, Haeusler, Gabrielle, McMullan, Brendan, Phillips, Marianne B, Padhye, Bhavna, Dalla-Pozza, Luciano, Alvaro, Frank, Fraser, Christopher J, Nicholls, Wayne, Clark, Julia E, O'Connor, Matthew, Saxon, Benjamin R, Tapp, Heather, Heath, John, Hunter, Sarah E, Tsui, Karen, Winstanley, Mark, Lyver, Amanda, Best, Emma J, Wadia, Ushma, Yeoh, Daniel, Blyth, Christopher C and Gottardo, Nicholas G (2022). COVID-19 vaccination in children and adolescents aged 5 years and older undergoing treatment for cancer and non-malignant haematological conditions: Australian and New Zealand Children’s Haematology/Oncology Group consensus statement. Medical Journal of Australia, 216 (6), 312-319. doi: 10.5694/mja2.51444
2022
Journal Article
Laparoscopic resection of a pediatric intestinal leiomyosarcoma
Brough, Dr David, Miller, Dr Greg, Ross, Dr Ian, Nicholls, Dr Wayne and Cavallucci, A/Prof David (2022). Laparoscopic resection of a pediatric intestinal leiomyosarcoma. Journal of Pediatric Surgery Case Reports, 79 102219, 102219. doi: 10.1016/j.epsc.2022.102219
2021
Journal Article
Enhancing natural killer cell targeting of pediatric sarcoma
Omer, Natacha, Nicholls, Wayne, Ruegg, Bronte, Souza-Fonseca-Guimaraes, Fernando and Rossi, Gustavo Rodrigues (2021). Enhancing natural killer cell targeting of pediatric sarcoma. Frontiers in Immunology, 12 791206, 791206. doi: 10.3389/fimmu.2021.791206
2021
Journal Article
Treatment and Outcomes for Central Nervous System Tumors in Australian Adolescents and Young Adults: A Population-Based National Study
Harrup, Rosemary, White, Victoria M., Coory, Michael, Walker, Rick, Anazodo, Antoinette, Skaczkowski, Gemma, Bibby, Helen, Osborn, Michael, Phillips, Marianne B., Conyers, Rachel, Thompson, Kate, Orme, Lisa M., Pinkerton, Ross and Nicholls, Wayne (2021). Treatment and Outcomes for Central Nervous System Tumors in Australian Adolescents and Young Adults: A Population-Based National Study. Journal of Adolescent and Young Adult Oncology, 10 (2), 202-208. doi: 10.1089/jayao.2020.0074
2021
Journal Article
Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03)
Gajjar, Amar, Robinson, Giles W., Smith, Kyle S., Lin, Tong, Merchant, Thomas E., Chintagumpala, Murali, Mahajan, Anita, Su, Jack, Bouffet, Eric, Bartels, Ute, Schechter, Tal, Hassall, Tim, Robertson, Thomas, Nicholls, Wayne, Gururangan, Sridharan, Schroeder, Kristin, Sullivan, Michael, Wheeler, Greg, Hansford, Jordan R., Kellie, Stewart J., McCowage, Geoffrey, Cohn, Richard, Fisher, Michael J., Krasin, Matthew J., Stewart, Clinton F., Broniscer, Alberto, Buchhalter, Ivo, Tatevossian, Ruth G., Orr, Brent A. ... Northcott, Paul A. (2021). Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03). Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 39 (7), 822-835. doi: 10.1200/JCO.20.01372
2020
Journal Article
Prevention of occlusion of cEnTral lInes for children with cancer: an implementation study
Ullman, Amanda J., Condon, Paula, Edwards, Rachel, Gibson, Victoria, Takashima, Mari, Schults, Jessica, Dean, Anna, Cattanach, Paula, Nicholls, Wayne, Osborne, Sonya, Rickard, Claire M., Cooke, Marie and Kleidon, Tricia (2020). Prevention of occlusion of cEnTral lInes for children with cancer: an implementation study. Journal of Paediatrics and Child Health, 56 (12), 1875-1884. doi: 10.1111/jpc.15067
2020
Journal Article
Primitive myxoid mesenchymal tumor of infancy in the orbit: a new location for a rare tumor
Hayes, Rylan A., Nicholls, Wayne, Davies, Janene and Sullivan, Timothy J. (2020). Primitive myxoid mesenchymal tumor of infancy in the orbit: a new location for a rare tumor. Ophthalmic Plastic and Reconstructive Surgery, 36 (4), e91-e93. doi: 10.1097/iop.0000000000001604
2020
Journal Article
Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1-2 trial
Geoerger, Birgit, Kang, Hyoung Jin, Yalon-Oren, Michal, Marshall, Lynley V., Vezina, Catherine, Pappo, Alberto, Laetsch, Theodore W., Petrilli, Antonio S., Ebinger, Martin, Toporski, Jacek, Glade-Bender, Julia, Nicholls, Wayne, Fox, Elizabeth, DuBois, Steven G., Macy, Margaret E., Cohn, Susan L., Pathiraja, Kumudu, Diede, Scott J., Ebbinghaus, Scot and Pinto, Navin (2020). Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1-2 trial. The Lancet Oncology, 21 (1), 121-133. doi: 10.1016/s1470-2045(19)30671-0
2019
Journal Article
Management of sarcoma in adolescents and young adults: an Australian population-based study
White, Victoria M., Orme, Lisa M., Skaczkowski, Gemma, Pinkerton, Ross, Coory, Michael, Osborn, Michael, Bibby, Helen, Nicholls, Wayne, Conyers, Rachel, Phillips, Marianne B., Harrup, Rosemary, Walker, Rick, Thompson, Kate and Anazodo, Antoinette (2019). Management of sarcoma in adolescents and young adults: an Australian population-based study. Journal of Adolescent and Young Adult Oncology, 8 (3), 272-280. doi: 10.1089/jayao.2018.0136
2018
Journal Article
Gender differences in doxorubicin pharmacology for subjects with chemosensitive cancers of young adulthood
Liu, Z., Martin, J., Orme, L., Seddon, B., Desai, J., Nicholls, W., Thomson, D., Porter, D., McCowage, G., Underhill, C., Cranswick, N., Michael, M., Zacharin, M., Herschtal, A., Sivasuthan, J. and Thomas, D. M. (2018). Gender differences in doxorubicin pharmacology for subjects with chemosensitive cancers of young adulthood. Cancer Chemotherapy and Pharmacology, 82 (5), 887-898. doi: 10.1007/s00280-018-3683-8
2018
Journal Article
Clinical management of Australian adolescents and young adults with acute lymphoblastic and myeloid leukemias: a national population-based study
White, V. M., Skaczkowski, G., Pinkerton, R., Coory, M., Osborn, M., Bibby, H., Nicholls, W., Orme, L. M., Conyers, R., Phillips, M. B., Harrup, R., Walker, R., Thompson, K. and Anazodo, A. (2018). Clinical management of Australian adolescents and young adults with acute lymphoblastic and myeloid leukemias: a national population-based study. Pediatric Blood & Cancer, 65 (11) e27349. doi: 10.1002/pbc.27349
2018
Journal Article
Clinical trial participation by adolescents and young adults with cancer: a continued cause for concern?
White, Victoria, Skaczkowski, Gemma, Anazodo, Antoinette, Bibby, Helen, Nicholls, Wayne, Pinkerton, Ross, Thompson, Kate, Orme, Lisa M., Conyers, Rachel, Osborn, Michael, Phillips, Marianne B., Harrup, Rosemary, Walker, Rick and Coory, Michael (2018). Clinical trial participation by adolescents and young adults with cancer: a continued cause for concern?. Seminars in Oncology, 45 (5-6), 275-283. doi: 10.1053/j.seminoncol.2018.04.002
2018
Journal Article
Osteogenic sarcoma in an adolescent with cystic fibrosis: successful treatment despite significant obstacles
Ruffles, Thomas J. C., Black, Ryan, Nicholls, Wayne, Laing, Barbara and Isles, Alan (2018). Osteogenic sarcoma in an adolescent with cystic fibrosis: successful treatment despite significant obstacles. Frontiers in Pediatrics, 6 245. doi: 10.3389/fped.2018.00245
2018
Journal Article
Factors influencing the documentation of fertility-related discussions for adolescents and young adults with cancer
Skaczkowski, G., White, V., Thompson, K., Bibby, H., Coory, M., Pinkerton, R., Nicholls, W., Orme, L. M., Conyers, R., Phillips, M. B., Osborn, M., Harrup, R. and Anazodo, A. (2018). Factors influencing the documentation of fertility-related discussions for adolescents and young adults with cancer. European Journal of Oncology Nursing, 34, 42-48. doi: 10.1016/j.ejon.2018.02.007
2018
Conference Publication
Queensland Youth Cancer Service: a partnership model to facilitate access to quality care for young people diagnosed with cancer
Bradford, Natalie K., Henney, Roslyn, Walker, Rick, Walpole, Euan, Kennedy, Glen, Nicholls, Wayne and Pinkerton, Ross (2018). Queensland Youth Cancer Service: a partnership model to facilitate access to quality care for young people diagnosed with cancer. New Rochelle, NY, United States: Mary Ann Liebert. doi: 10.1089/jayao.2017.0080
2018
Journal Article
Experiences of care of adolescents and young adults with cancer in Australia
White, Victoria, Skaczkowski, Gemma, Thompson, Kate, Bibby, Helen, Coory, Michael, Pinkerton, Ross, Nicholls, Wayne, Orme, Lisa M., Conyers, Rachel, Phillips, Marianne B., Osborn, Michael, Harrup, Rosemary and Anazodo, Antoinette (2018). Experiences of care of adolescents and young adults with cancer in Australia. Journal of Adolescent and Young Adult Oncology, 7 (3), 315-325. doi: 10.1089/jayao.2017.0104
2017
Journal Article
Phase 1/2 KEYNOTE-051 study of pembrolizumab (pembro) in pediatric patients (pts) with advanced melanoma or a PD-L1<sup>+</sup> advanced, relapsed, or refractory solid tumor or lymphoma
Geoerger, Birgit, Kang, Hyoung Jin, Yalon-Oren, Michal, Marshall, Lynley V., Vezina, Catherine, Pappo, Alberto S., Laetsch, Theodore Willis, Petrilli, Antonio Sergio, Handgretinger, Rupert, Toporski, Jacek, Glade-Bender, Julia, Nicholls, Wayne, Fox, Elizabeth, DuBois, Steven G., Macy, Margaret, Cohn, Susan Lerner, Pathiraja, Kumudu, Diede, Scott J., Ebbinghaus, Scot and Pinto, Navin R. (2017). Phase 1/2 KEYNOTE-051 study of pembrolizumab (pembro) in pediatric patients (pts) with advanced melanoma or a PD-L1+ advanced, relapsed, or refractory solid tumor or lymphoma. Journal of Clinical Oncology, 35 (S15), 10525-10525. doi: 10.1200/jco.2017.35.15_suppl.10525
Funding
Current funding
Supervision
Availability
- Associate Professor Wayne Nicholls is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
KIR-mismatched NK-cells graft-versus-paediatric sarcoma effect
Associate Advisor
Other advisors: Dr Gustavo Rodrigues Rossi, Associate Professor Fernando Guimaraes
Media
Enquiries
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