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2024

Journal Article

The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy

McCulloch, Timothy R, Rossi, Gustavo R, Miranda‐Hernandez, Socorro, Valencia‐Hernandez, Ana Maria, Alim, Louisa, Belle, Clemence J, Krause, Andrew, Zacchi, Lucia F, Lam, Pui Yeng, Nakamura, Kyohei, Kupz, Andreas, Wells, Timothy J and Souza‐Fonseca‐Guimaraes, Fernando (2024). The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy. Immunology & Cell Biology. doi: 10.1111/imcb.12794

The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy

2024

Journal Article

TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer

Wong, Joshua K.M., McCulloch, Timothy R., Alim, Louisa, Omer, Natacha, Mehdi, Ahmed M., Tuong, Zewen Kelvin, Bonfim-Melo, Alexis, Chung, Eric, Nicol, Alice, Simpson, Fiona, Rhee, Handoo, Rossi, Gustavo Rodrigues and Souza-Fonseca-Guimaraes, Fernando (2024). TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer. eBioMedicine, 104 105176, 105176. doi: 10.1016/j.ebiom.2024.105176

TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer

2024

Journal Article

Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis

Tu, Cui, Buckle, Irina, Leal Rojas, Ingrid, Rossi, Gustavo Rodrigues, Sester, David P, Moore, Andrew S, Radford, Kristen, Guillerey, Camille and Souza‐Fonseca‐Guimaraes, Fernando (2024). Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis. Clinical & Translational Immunology, 13 (3) e1501, e1501. doi: 10.1002/cti2.1501

Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis

2023

Journal Article

Development of physiologically relevant skin organoids from human induced pluripotent stem cells

Shafiee, Abbas, Sun, Jane, Ahmed, Imaan A., Phua, Felicia, Rossi, Gustavo R., Lin, Cheng‐Yu, Souza‐Fonseca‐Guimaraes, Fernando, Wolvetang, Ernst J., Brown, Jason and Khosrotehrani, Kiarash (2023). Development of physiologically relevant skin organoids from human induced pluripotent stem cells. Small, 20 (16) e2304879, 1-14. doi: 10.1002/smll.202304879

Development of physiologically relevant skin organoids from human induced pluripotent stem cells

2023

Journal Article

Differential regulation of natural killer cells by tumor necrosis factor receptors 1 and 2

McCulloch, Timothy R., Rossi, Gustavo Rodrigues, Lam, Allie, Wong, Joshua, Kane, Lawrence P, Herold, Marco, Wells, Timothy and Souza-Fonseca-Guimaraes, Fernando (2023). Differential regulation of natural killer cells by tumor necrosis factor receptors 1 and 2. The Journal of Immunology, 210 (S1), 72.28-72.28. doi: 10.4049/jimmunol.210.supp.72.28

Differential regulation of natural killer cells by tumor necrosis factor receptors 1 and 2

2023

Journal Article

Fucoidan from Spatoglossum schröederi promotes B16-F10 malignancy features modulation and antimelanoma in vivo activities

Bellan, D.L., Bini, I.H., Santi, F.C., Rossi, G.R., Biscaia, S.M.P., Maximo, A.I., Reis, M.B., Simas, F.F., Oliveira, C.C., Winnischofer, S.M.B., Leme, D.M., Chammas, R., Rocha, H.A.O. and Trindade, E.S. (2023). Fucoidan from Spatoglossum schröederi promotes B16-F10 malignancy features modulation and antimelanoma in vivo activities. Algal Research, 72 103134, 1-12. doi: 10.1016/j.algal.2023.103134

Fucoidan from Spatoglossum schröederi promotes B16-F10 malignancy features modulation and antimelanoma in vivo activities

2023

Journal Article

IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study

Shojaei, Maryam, Shamshirian, Amir, Monkman, James, Grice, Laura, Tran, Minh, Tan, Chin Wee, Teo, Siok Min, Rodrigues Rossi, Gustavo, McCulloch, Timothy R., Nalos, Marek, Raei, Maedeh, Razavi, Alireza, Ghasemian, Roya, Gheibi, Mobina, Roozbeh, Fatemeh, Sly, Peter D., Spann, Kirsten M., Chew, Keng Yih, Zhu, Yanshan, Xia, Yao, Wells, Timothy J., Senegaglia, Alexandra Cristina, Kuniyoshi, Carmen Lúcia, Franck, Claudio Luciano, dos Santos, Anna Flavia Ribeiro, Noronha, Lucia de, Motamen, Sepideh, Valadan, Reza, Amjadi, Omolbanin ... Tang, Benjamin (2023). IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study. Frontiers in Immunology, 13 1060438, 1-14. doi: 10.3389/fimmu.2022.1060438

IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study

2022

Journal Article

A simple method to evaluate the toxic effects of Prorocentrum lima extracts to fish (sea bass) kidney cells

da Silva, Cesar Aparecido, Mafra, Luiz Laureno, Rossi, Gustavo Rodrigues, da Silva Trindade, Edvaldo and Matias, William Gerson (2022). A simple method to evaluate the toxic effects of Prorocentrum lima extracts to fish (sea bass) kidney cells. Toxicology in Vitro, 85 105476, 1-8. doi: 10.1016/j.tiv.2022.105476

A simple method to evaluate the toxic effects of Prorocentrum lima extracts to fish (sea bass) kidney cells

2022

Journal Article

Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy

Raza, Aun, Rossi, Gustavo Rodrigues, Janjua, Taskeen Iqbal, Souza-Fonseca-Guimaraes, Fernando and Popat, Amirali (2022). Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy. Trends in Biotechnology, 41 (1), 77-92. doi: 10.1016/j.tibtech.2022.06.011

Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy

2022

Journal Article

TGF-β and CIS inhibition overcomes NK cell suppression to restore anti-tumor immunity

Souza-Fonseca Guimaraes, Fernando, Rossi, Gustavo R., Dagley, Laura F., Foroutan, Momeneh, McCulloch, Timothy R., Yousef, Jumana, Park, Hae-Young, Gunter, Jennifer H., Beavis, Paul A., Lin, Cheng-Yu, Hediyeh-zadeh, Soroor, Camilleri, Tania, Davis, Melissa J. and Huntington, Nicholas D. (2022). TGF-β and CIS inhibition overcomes NK cell suppression to restore anti-tumor immunity. Cancer Immunology Research, 10 (9), 1047-1054. doi: 10.1158/2326-6066.cir-21-1052

TGF-β and CIS inhibition overcomes NK cell suppression to restore anti-tumor immunity

2022

Journal Article

CIS and TGF ‐β regulatory pathways influence immunity to bacterial infection

McCulloch, Timothy R., Rossi, Gustavo R., Schreuder, Jaring, Belz, Gabrielle T., Wells, Timothy J. and Souza‐Fonseca‐Guimaraes, Fernando (2022). CIS and TGF ‐β regulatory pathways influence immunity to bacterial infection. Immunology, 167 (1), 54-63. doi: 10.1111/imm.13516

CIS and TGF ‐β regulatory pathways influence immunity to bacterial infection

2022

Journal Article

Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures

Kulasinghe, Arutha, Tan, Chin Wee, dos Santos Miggiolaro, Anna Flavia Ribeiro, Monkman, James, SadeghiRad, Habib, Bhuva, Dharmesh D., da Silva Motta Junior, Jarbas, Vaz de Paula, Caroline Busatta, Nagashima, Seigo, Baena, Cristina Pellegrino, Souza-Fonseca-Guimaraes, Paulo, de Noronha, Lucia, McCulloch, Timothy, Rodrigues Rossi, Gustavo, Cooper, Caroline, Tang, Benjamin, Short, Kirsty R., Davis, Melissa J., Souza-Fonseca-Guimaraes, Fernando, Belz, Gabrielle T. and O'Byrne, Ken (2022). Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures. European Respiratory Journal, 59 (6) 2101881, 1-19. doi: 10.1183/13993003.01881-2021

Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures

2021

Journal Article

Enhancing natural killer cell targeting of pediatric sarcoma

Omer, Natacha, Nicholls, Wayne, Ruegg, Bronte, Souza-Fonseca-Guimaraes, Fernando and Rossi, Gustavo Rodrigues (2021). Enhancing natural killer cell targeting of pediatric sarcoma. Frontiers in Immunology, 12 791206, 791206. doi: 10.3389/fimmu.2021.791206

Enhancing natural killer cell targeting of pediatric sarcoma

2021

Journal Article

Electrospun polyvinyl-alcohol/gum arabic nanofibers: biomimetic platform for in vitro cell growth and cancer nanomedicine delivery

Serio, Francesca, da Cruz, Anderson Fraga, Chandra, Anil, Nobile, Concetta, Rossi, Gustavo Rodrigues, D'Amone, Eliana, Gigli, Giuseppe, del Mercato, Loretta Laureana and de Oliveira, Carolina Camargo (2021). Electrospun polyvinyl-alcohol/gum arabic nanofibers: biomimetic platform for in vitro cell growth and cancer nanomedicine delivery. International Journal of Biological Macromolecules, 188, 764-773. doi: 10.1016/j.ijbiomac.2021.08.069

Electrospun polyvinyl-alcohol/gum arabic nanofibers: biomimetic platform for in vitro cell growth and cancer nanomedicine delivery

2021

Journal Article

Biocompatible gum arabic-gold nanorod composite as an effective therapy for mistreated melanomas

Gonçalves, Jenifer P., da Cruz, Anderson F., Nunes, Ábner M., Meneghetti, Mario R., de Barros, Heloise R., Borges, Beatriz S., de Medeiros, Lia C.A.S., Soares, Maurilio J., dos Santos, Mayara P., Grassi, Marco T., Rossi, Gustavo R., Bellan, Daniel L., Biscaia, Stellee M.P., Cristal, Aline M., Buzzo, João L.A., Ribeiro, Yasmin C., Acco, Alexandra, Cardoso, Mateus B., Simas, Fernanda F., Trindade, Edvaldo S., Riegel-Vidotti, Izabel C. and de Oliveira, Carolina C. (2021). Biocompatible gum arabic-gold nanorod composite as an effective therapy for mistreated melanomas. International Journal of Biological Macromolecules, 185, 551-561. doi: 10.1016/j.ijbiomac.2021.06.172

Biocompatible gum arabic-gold nanorod composite as an effective therapy for mistreated melanomas

2021

Journal Article

Production of a novel recombinant brown spider hyaluronidase in baculovirus-infected insect cells

De-Bona, Elidiana, Chaves-Moreira, Daniele, Batista, Thiago Beltrami Dias, Justa, Hanna Câmara da, Rossi, Gustavo Rodrigues, Antunes, Bruno Cesar, Matsubara, Fernando Hitomi, Minozzo, João Carlos, Wille, Ana Carolina Martins, Veiga, Silvio Sanches, Senff-Ribeiro, Andrea and Gremski, Luiza Helena (2021). Production of a novel recombinant brown spider hyaluronidase in baculovirus-infected insect cells. Enzyme and Microbial Technology, 146 109759, 1-13. doi: 10.1016/j.enzmictec.2021.109759

Production of a novel recombinant brown spider hyaluronidase in baculovirus-infected insect cells

2020

Journal Article

Green does not always mean go: a sulfated galactan from Codium isthmocladum green seaweed reduces melanoma metastasis through direct regulation of malignancy features

Bellan, D.L., Biscaia, S.M.P., Rossi, G.R., Cristal, A.M., Gonçalves, J.P., Oliveira, C.C., Simas, F.F., Sabry, D.A., Rocha, H.A.O., Franco, C.R.C., Chammas, R., Gillies, R.J. and Trindade, E.S. (2020). Green does not always mean go: a sulfated galactan from Codium isthmocladum green seaweed reduces melanoma metastasis through direct regulation of malignancy features. Carbohydrate Polymers, 250 116869, 116869. doi: 10.1016/j.carbpol.2020.116869

Green does not always mean go: a sulfated galactan from Codium isthmocladum green seaweed reduces melanoma metastasis through direct regulation of malignancy features

2020

Journal Article

Beyond gold nanoparticles cytotoxicity: potential to impair metastasis hallmarks

Pendiuk Gonçalves, Jenifer, Fraga da Cruz, Anderson, Ribeiro de Barros, Heloise, Santana Borges, Beatriz, Almeida Soares de Medeiros, Lia Carolina, Soares, Maurilio José, Padovan dos Santos, Mayara, Grassi, Marco Tadeu, Chandra, Anil, del Mercato, Loretta Laureana, Rodrigues Rossi, Gustavo, da Silva Trindade, Edvaldo, Riegel-Vidotti, Izabel Cristina and Camargo de Oliveira, Carolina (2020). Beyond gold nanoparticles cytotoxicity: potential to impair metastasis hallmarks. European Journal of Pharmaceutics and Biopharmaceutics, 157, 221-232. doi: 10.1016/j.ejpb.2020.10.019

Beyond gold nanoparticles cytotoxicity: potential to impair metastasis hallmarks

2020

Journal Article

The antitumor effect of heparin is not mediated by direct NK cell activation

Rossi, Gustavo R., Gonçalves, Jenifer P., McCulloch, Timothy, Delconte, Rebecca B., Hennessy, Robert J., Huntington, Nicholas D., Trindade, Edvaldo S. and Souza-Fonseca-Guimaraes, Fernando (2020). The antitumor effect of heparin is not mediated by direct NK cell activation. Journal of Clinical Medicine, 9 (8) 2666, 2666-11. doi: 10.3390/jcm9082666

The antitumor effect of heparin is not mediated by direct NK cell activation

2020

Journal Article

Tumor microenvironment-associated extracellular matrix components regulate NK cell function

Rossi, Gustavo Rodrigues, Trindade, Edvaldo S. and Souza-Fonseca-Guimaraes, Fernando (2020). Tumor microenvironment-associated extracellular matrix components regulate NK cell function. Frontiers in Immunology, 11 73, 73. doi: 10.3389/fimmu.2020.00073

Tumor microenvironment-associated extracellular matrix components regulate NK cell function