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Dr. Nguyen is an expert in applying long-read Oxford Nanopore Sequencing Technologies (ONT) in agriculture, particularly livestock and other sectors. Her groundbreaking contributions include being the pioneer in sequencing the genomes of Brahman and Wagyu cattle, developing an innovative epigenetic clock for age prediction in cattle, and successfully implementing ONT portable sequencers for Blockchain traceability systems in Australia.

As a leader in the field, Dr. Nguyen spearheads the use of ONT long-read technology to scaffold genome assemblies in livestock, plants, protists, and insects. Her multidisciplinary expertise in molecular biology, advanced genomics, and animal sciences also empowers her to explore causative markers for commercial SNP arrays and identify significant DNA variants from low-coverage sequencing data sets.

Dr. Nguyen's exceptional achievements and expertise have been acknowledged through the prestigious ARC Industry Fellowship, recognising her as a promising early career researcher. Her work has significantly contributed to advancing genomic research in agriculture and has opened new avenues for utilising ONT sequencing technologies across diverse domains.

Dr Quan Nguyen is a Group Leader at the Institute for Molecular Bioscience (IMB), The University of Queensland. He is leading the Genomics and Machine Learning (GML) lab to study neuroinflammation and cancer-immune cells at single-cell resolution and within spatial morphological tissue context. His research interest is about revealing gene and cell regulators that determine the states of the complex cancer and neuronal ecosystems. Particularly, he is interested in quantifying cellular diversity and the dynamics of cell-cell interactions within the tissues to find ways to improve cancer diagnosis or cell-type specific treatments or the immunoinflammation responses that cause neuronal disease.

Using machine learning and genomic approaches, his group are integrating single-cell spatiotemporal sequencing data with tissue imaging data to find causal links between cellular genotypes, tissue microenvironment, and disease phenotypes. GML lab is also developing experimental technologies that enable large-scale profiling of spatial gene and protein expression (spatial omics) in a range of cancer tissues (focusing on brain and skin cancer) and in mouse brain and spinal cord.

Dr Quan Nguyen completed a PhD in Bioengineering at the University of Queensland in 2013, postdoctoral training in Bioinformatics at RIKEN institute in Japan in 2015, a CSIRO Office of Chief Executive (OCE) Research Fellowship in 2016, an IMB Fellow in 2018, an Australian Research Council DECRA fellowship (2019-2021), and is currently a National Health and Medical Research Council leadership fellow (EL2). He has published in top-tier journals, including Cell, Cell Stem Cell, Nature Methods, Nature Protocols, Nature Communications, Genome Research, Genome Biology and a prize-winning paper in GigaScience. In the past three years, he has contributed to the development of x8 open-source software, x2 web applications, and x4 databases for analysis of single-cell data and spatial transcriptomics. He is looking for enthusiastic research students and research staff to join his group.

Professor Lars Nielsen is leading the development of experimental and computational tools to analyse and design complex biological systems. His expertise in metabolic modelling and flux analysis is available nowhere else in Australia – and in few labs across the world. Professor Nielsen’s studies of biological systems as diverse as bacteria, baker's yeast, sugarcane, insects and mammals has attracted industrial partnerships with companies including Dow, Metabolix, Amyris, LanzaTech, Boeing, Virgin Australia and GE. These metabolic engineering partnerships have focussed on developing new ways of producing aviation fuel, various materials and bioactives (antibiotics, biopesticides, monoclonal antibodies). Professor Nielsen is also applying system analysis and design approaches to tissue engineering including novel strategies for generating microtissues for drug screening and using stem cells to produce red and white blood cells for transfusion.

International links

Professor Nielsen collaborates with some of the world’s pre-eminent metabolic engineers. A joint project with Prof Sang Yup Lee (KAIST, Korea) enabled several extended mutual visits to explore use of sugar for higher value products. A separate project focused on producing synthetic aviation fuel based on isoprenoids involves Professor Nielsen collaborating with global synthetic biotechnology company Amyris and leading isoprenoid metabolic engineer Professor Jay Keasling, from UC Berkeley. Professor Nielsen has secured $8million since 2006 from industry through research grants with US, European, Japanese, Korean, New Zealand and Australian companies.

Dr Marloes Dekker Nitert is an Associate Professor at The University of Queensland. Marloes is a biomedical researcher with a PhD from Lund University in Sweden. Her research focuses on the role of metabolism in complications of pregnancy. She currently heads a laboratory research group at the School of Chemistry and Molecular Biosciences studying the role of metabolism in pregnancy complications and especially how the gut microbiome contributes to a healthy pregnancy and to pregnancy complications. Marloes works closely together with clinician-scientists and clinicians at the Royal Brisbane and Women’s Hospital and the Mater Mothers' Hospital to do her translational research. Marloes is a board member of the Australian Society for Medical Research and a past Council member of the Society of Obstetric Medicine Australia and New Zealand.

Michael Noad graduated with a Bachelor of Veterinary Science from UQ in 1990. After working primarily as a small animal vet in Queensland and the UK, Mike returned to Australia to undertake a PhD in humpback whale acoustic behaviour at the University of Sydney in 1995. In 2002, after finishing his PhD, Mike became a postdoctoral fellow in the School of Integraitve Biology at UQ. In 2003 he was employed as a lecturer in the School of Veterinary Science. He is currently a professor at UQ, dividing his time between veterinary science, where he teaches anatomy, and marine science, the focus of his research. In 2019 he became the Academic Director of the Moreton Bay Research Station, and in 2022 the Director of the Centre for Marine Science while still retaining a substantive apointment in the School of Veterinary Science.

Research:

The key areas of Mike's research are the effects of anthopogenic underwater noise on whales, the evolution and function of humpback whale song, social learning and culture in animals, and marine mammal population ecology. With regards to the effects of anthropogenic underwater noise on whales, there is currently a great deal of concern about how anthropogenic noise such as military sonar, oil and gas exploration activity and commercial shipping traffic, may adversely affect marine mammals. Mike has been involved in several large collaborative projects in this area, the largest being BRAHSS where the team studied the behavioural changes of humpback whales in response to powerful seismic airguns. His work on the evolution and function of humpback whale song is focused on how the animals themselves use sound to communicate. The songs of these whales is one of the most complex acoustic displays of any animal known. The songs are not static, but constantly change, and although the songs are almost certainly used as a sexual signal, the changing nature of the song makes understanding how this works challenging. His work on social learning and culture in animals also involves humpback whale songs, but focuses on how the whales learn the songs from each other, both within and between populations. As the patterns are usually unique to a population but can be transmitted over time to other populations, humpback song is the most extreme example of a vocal cultural trait in any species as well as an excellent model for studying social learning, the process whereby the whales perceive and learn new songs. Mike's last research area is marine mammal population ecology, and the primary project is the population ecology of the east Australian humpback whales. This population was almost completely extirpated in the early 1960s through hunting, but has since undergone a rapid recovery. Its long term trajectory, however, is uncertain due to a number of factors including possibly overshooting the natural carrying capacity of the population, and climate change.

Megan O’Mara is a Professor and Group Leader at the Australian Institute for Bioengineering and Nanotechnology (AIBN), UQ. Her group uses multiscale modelling techniques to understand how changes in the biochemical environment of the cell membranes alters membrane properties and modulates the function of membrane proteins. She has research interests in multidrug resistance, computational drug design and delivery, biopolymers, and personalized medicine. Megan completed her PhD in biophysics at the Australian National University in 2005 before moving to the University of Calgary, Canada, to take up a Canadian Institutes of Health Research Postdoctoral Fellowship. In 2009, she returned to Australia to join University of Queensland’s School of Chemistry and Molecular Biosciences as a UQ Postdoctoral Fellow, before commencing an ARC DECRA in 2012 where she continued her computational work on membrane protein dynamics. In 2015, Megan joined the Research School of Chemistry, Australian National University in 2015 as Rita Cornforth Fellow and Senior Lecturer. In 2019 she was promoted to Associate Professor and was Associate Director (Education) of the Research School of Chemistry ANU in 2019-2021. In April 2022 she relocated to AIBN.

Professor Obermair is the Director of Queensland Centre for Gynaecological Cancer Research (QCGC Research). He is a Professor of Gynaecological Oncology since 2007, a Senior Medical Officer at Royal Brisbane & Women’s Hospital and a Visiting Medical Officer at St Andrews War Memorial Hospital and Buderim Private Hospital. He holds an Honorary title of Professor at UQ since 2006.

Professor Obermair is an internationally recognised leader in gynaecological oncology research and treatment and has lead the research team at QCGC Research since establishing it in 2003.

I studied Technical Mathematics at the Vienna University of Technology. I also earned a Master's degree in Law and I finished the first ("non-clinical") part of Medical Studies at the University of Vienna. I earned my PhD in Applied Mathematics at the University of Vienna in 2007. My PhD advisor was Christian Schmeiser, my co-advisor was Peter Markowich. I spent several months at the University of Buenos Aires working with C. Lederman and at the ENS-Paris rue d'Ulm in the group of B. Perthame.

Before coming to UQ, I held post-doc positions at the Wolfgang Pauli Insitute (Vienna), University of Vienna and the Austrian Academy of Sciences (RICAM). In 2013 I won an Erwin Schrödinger Fellowship of the Austrian Science Fund (FWF). I was a post-doc researcher in the group of Alex Mogilner first at UC Davis, then at the Courant Institute of Math. Sciences (New York University).

I moved to UQ in Dec. 2016. More recently, in 2024, I spent 4 months at the department of Mathemetics of the U. of Heidelberg as a visiting scientist.

Dr. Melanie Oey is currently Research Officer at the Institute for Molecular Bioscience in the Group of Prof. Ben Hankamer. She was born in Berlin, Germany, and went to the University of Potsdam to study Biochemistry. During her studies she worked at the Max-Planck Institute of Molecular Plant Physiology in Golm, Germany, where she also received her Ph.D. in 2009 for her work on the production of lysin antibiotics in tobacco plants. In the same year she came to Australia to work at the University of Queensland, and has since then developed new technologies which are base for the newly launched "Breakthrough Science Program in Algal Biomedicine" at the Institute for Molecular Bioscience.

Her research interestes are:

- High value product production (e.g. vaccines, antibiotics, pain killer) in Algae via chloroplast and nuclear transformation

- Improvement of bio-hydrogen production from microalgae

- Development of new molecular tools for microalgae

Her work has been funded by the Australian Research Council (ARC), the National Health and Medical Research Council (NHMRC) and the German Academic Exchange Service (DAAD).

Dr. Ong is an exceptional and driven researcher in the field of Animal Health, and her work revolves around studying pathogen genomes, transcriptomes, and host-associated metagenomes to enhance animals' resistance to diseases and improve their overall health and productivity.

One remarkable aspect of Dr. Ong's expertise is her versatility and enthusiasm for both wet lab and dry lab (bioinformatics) work. She finds equal joy in conducting hands-on experiments in the wet lab and diving into data analysis and computational work in the bioinformatics domain. This multidisciplinary approach empowers her to gain comprehensive insights into her research subjects and tackle complex challenges from various angles. Dr. Ong's vast skillset encompasses molecular biology and expertise in utilizing 2nd and 3rd generation sequencing technologies, along with her proficiency in bioinformatics tools and techniques. This diverse knowledge allows her to explore and employ cutting-edge methodologies, providing her with a unique advantage in her research endeavors.

One of Dr. Ong's significant achievements was conducting the first cattle reproductive tract metagenomic study in Australia. This groundbreaking study likely contributed valuable information about the reproductive health of cattle and opened new avenues for further research in this area. Additionally, her contributions extend to the assembly of complete genomes for multiple pathogens, such as Campylobacter fetus and Bovicola ovis. This accomplishment is instrumental in understanding these pathogens' genetic makeup, evolution, and mechanisms of infection, which is vital in developing targeted strategies to combat diseases affecting animals.

Keywords: Microbiome and Metagenomics, Pathogen genomics, Animal health, PCR, Sequencing, Host-microbe interactions

In The Ortiz-Barrientos Lab we seek to understand how natural selection drives the origin of traits and new species. We combine empirical and theoretical approaches from across multiple disciplines.

We are located in beautiful Brisbane, Australia, in the School of The Environment at The University of Queensland.

Please explore our pages to learn about research, culture, and the team of scientists that bring their passion and creativity to discovering how nature works.

Career Summary: 2009: PhD, University of Michigan, USA with training in cardiac physiology, modelling myocardial ischemia in vivo and in vitro, and development of therapeutic approaches for myocardial ischemia; 2009–2015: Postdoctoral Research Fellow, University of Washington, Institute for Stem Cell and Regenerative Medicine, USA with training in stem cell biology, genomics, genome editing, and cell therapeutics for ischemic heart disease; 2015–current: Group Leader, University of Queensland (UQ), Institute for Molecular Bioscience; 2022-current: Associate Professor, UQ; 2018–2021 and 2023-2026: National Heart Foundation Future Leader Fellow. Dr. Palpant’s research team has expertise in human stem cell biology, computational genomics, and cardiac physiology, which enables them to translate outcomes from cell biology and genomics to disease modelling, drug discovery, and preclinical modelling.

Marie-Odile Parat (MO) joined the School of Pharmacy as Senior Lecturer in December 2007.

MO obtained her Pharm.D. from University Joseph Fourier in Grenoble, France, a Masters in Cutaneous Biology from University Claude Bernard in Lyon, France and her Ph.D. in Cell Biology from University Joseph Fourier in Grenoble, France. She further has post graduate diplomas in the fields of Biomedical and Industrial Pharmacy, Photobiology, Pharmaceutical Management, and Public Health.

MO did her Pharmaceutical Residency at the University Hospitals of Grenoble, France in the Sterile Pharmaceutical Supplies Headquarters, the Department of Nuclear Medicine, and the Laboratory Medicine Department of Biochemistry. Attracted by international working experience, she carried out research within the R&D laboratories of Estee Lauder in Melville, NY. She further worked for the United Nations International Trade center in Geneva, Switzerland, where she was the Product Specialist on market information for pharmaceutical raw materials/essential drugs for three years in collaboration with the World Health Organization.

She later performed post-doctoral research in the Universidade de São Paulo, SP, Brasil and The Cleveland Clinic Foundation in the United States. She was appointed as a Staff Scientist in the Center for Anesthesiology Research of the Cleveland Clinic in 2003, an Assistant Professor of Molecular Medicine in the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, and a Member of the Case Cancer Center.

During her research career MO has attracted awards from various funding agencies including the Research Funding Agency of the State of São Paulo (FAPESP), the American Heart Association, the Ohio Cancer Research Associates, the American Cancer Society, the National Heart Foundation of Australia, Cancer Council Queensland, Australian and New Zealand College of Anaesthetists and the Australia Research Council (ARC).

The long term goal of the Parat laboratory is to provide insight for novel cancer therapies. A basic science team focusses on endothelial and cancer cell migration, invasion, angiogenesis, and specialized plasma membrane subdomains termed caveolae. A translational axis of research evaluates novel mechanisms by which opioids administered to cancer patients modulate the risk of long term tumour recurrence and metastasis.

I am a molecular virologist and postdoctoral research fellow in Prof. Alexander Khromykh's laboratory, specialising in virus evolution, virus bioinformatics, and reverse genetics.

My research journey began with a Bachelor of Science, First Class Honours in Molecular Biology from The University of Queensland (2015). I then pursued my PhD (2016-2021) at UQ's School of Biology under Prof. Sassan Asgari, where I analysed the virome and microbiome of Aedes aegypti and Aedes albopictus mosquitoes, focusing on their interactions with Wolbachia pipientis infections.

Since 2021, I have been a postdoctoral researcher in Prof. Alexander Khromykh's RNA Virology lab. Here, I contributed to developing the SARS-CoV-2 circular polymerase extension reaction (CPER) reverse-genetics methodology. As a physical containment 3 (PC3) researcher, I examine the virological properties of Flaviviruses and SARS-CoV-2 viruses under stringent PC3 conditions. Recently, with support from Therapeutic Innovation Australia and the Australian Infectious Diseases Research Centre, I have been utilising the Kunjin virus replicon system as a versatile and durable self-replicating RNA platform for vaccine and protein replacement therapy.

Beyond my virology work, I actively provide bioinformatics and phylogenetics support within UQ and internationally. Let's connect if you’re interested in collaborating on differential gene and ncRNA expression analysis, ATAC-sequencing, ancestral state prediction, virus discovery, or microbiome analyses.

I am also on the organising committee of MicroSeq (2023-2024), an Australasian Microbiology conference focused on microbial sequencing promoting PhD students and early career researchers. Additionally, I am an incoming Ex Officio member of the Australian Society for Microbiology (ASM) Queensland branch.

Our research focuses on understanding how cells work and what goes wrong in disease. We are studying the role of cellular organelles in defence against pathogens, the molecular changes underlying muscle disease, and optimising methods to deliver therapeutics to specific cell types in whole animals.

Professor Robert Parton is an ARC Laureate Fellow, a group leader in the IMB Centre for Cell Biology of Chronic Disease, and Deputy Director of the Centre for Microscopy and Microanalysis. He is a Fellow of the Australian Academy of Science and an Associate Member of EMBO.