Centre Director of Queensland Digital Health Centre
Queensland Digital Health Centre
Faculty of Health, Medicine and Behavioural Sciences
Conjoint Professor
Centre for Health Services Research
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Not available for supervision
Professor Clair Sullivan is an internationally-recognised leading practising and academic clinical informatician who helps drive digital health transformation in Queensland and globally.
Clair is the Director of the new Queensland Digital Health Centre within the Centre for Health Research at The University of Queensland.
A specialist endocrinologist, Clair graduated with Honours in Medicine from The University of Queensland and earned a Research Doctorate in Medicine from the University of Leeds. In 2014, Clair began a parallel career in the emerging field of digital health and has held significant leadership roles in digital health practice and governance across government and academia. Her work is regularly translated into practice and informs policy in Australia and globally.
Clair was appointed Associate Professor of Medicine in Clinical Informatics at UQ and is an Adjunct Professor at the Faculty of Health, Queensland University of Technology and an Adjunct Professor, School of Health and Biomedical Sciences at Royal Melbourne Institute of Technology.
She is a fellow of the Royal Australasian College of Physicians, the Australian College of Health Informatics and the Australasian Institute of Digital Health.
Clair serves on several national advisory boards for digital health. She is the recipient of several awards including the 2021 Premier’s Award for Excellence for her team’s work on the digital response to COVID-19 and the 2022 Telstra Brilliant Connected Women in Digital Health Award.
She has generated over $30M in grant funding and has deep collaborations with government and industry. She is ranked in the top 1% of Medical Informatics researchers globally.
Faculty of Health, Medicine and Behavioural Sciences
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Not available for supervision
Media expert
Dr Daniel Sullivan is a Clinical Psychologist and Adjunct Lecturer in the Child Health Research Centre, The University of Queensland. In his clinical role, Dr Sullivan leads a program of research to design Australia's first psychology extended scope of practice model of care for limited pharmacotherapy management, with an emphasis on deprescribing hypnotic medicines in the public sector sleep psychology setting (ExPEDiTe Sleep project). As a member of the Let’s Yarn about Sleep group at the University of the Sunshine Coast, Dr Sullivan is working to improve sleep health equity for First Nations Australians through community co-designed, culturally responsive sleep programs which harmonise sleep science with Indigenous Australian perspectives and knowledges about sleep.
Dr Sullivan’s research and clinical expertise is in the behavioural aspects of sleep; he is an Editor of the journal Research Directions: Sleep Psychology (Cambridge University Press) and is board certified by the US-based Board of Behavioral Sleep Medicine. Dr Sullivan completed postgraduate training in sleep at the University of Sydney (MSc), and his PhD in Clinical Psychology at Griffith University, where his doctoral research examined psychological factors involved in sleep-related headaches.
Centre Director of Centre for Nutrition and Food Sciences
Centre for Nutrition and Food Sciences
Queensland Alliance for Agriculture and Food Innovation
Affiliate of Centre for Geoanalytical Mass Spectrometry
Centre for Geoanalytical Mass Spectrometry
Faculty of Science
Centre Director, Nutrition & Food Science
Queensland Alliance for Agriculture and Food Innovation
Availability:
Not available for supervision
Professor Yasmina Sultanbawa's research is focused within the agribusiness development framework, specifically in the area of food processing, preservation, food safety and nutrition. Her current research includes the minimisation of post harvest losses through value addition and the search for natural preservatives to replace current synthetic chemicals. In addition, her research area also includes the challenge of nutrition security, in particular micronutrient deficiency (hidden hunger), lack of diet diversity and nutritional losses in the food supply chain, which are addressed by her work with underutilized Australian plant species and potential new crops. Her work on Australian native plant foods is focused on incorporation of these plants in mainstream agriculture and diet diversification Working with indigenous communities to develop nutritious and sustainable value added products from native plants for use in the food, feed, cosmetic and health care industries is a key strategy. The creation of employment, economic and social benefits to these remote communities is an anticipated outcome. She considers it a privilege to engage with these communities and is very passionate that her work will have a positive socio-economic impact.
Research Focus
Functional ingredients (natural additives)
Functional food/feed/nutraceutical ingredients with enhanced nutritional and phytochemical profiles are obtained from specialty crops (Australian native plant foods) and industry co/by-products. Natural additives are obtained from raw materials of vegetable, fruit, herbs/spices or microbiological origin. An example is plant extracts which can provide e.g. antioxidants, shelf-life extension (natural antimicrobials), trace-nutrients (vitamins/ minerals) and novel flavours. Innovative technology solutions
Novel packaging systems
Development of active, biodegradable packaging material with natural additives for shelf life extension, smart packaging with nanosensors for the effective detection of food contaminants, microperforated packaging systems with optimised modified atmospheres for fresh foods and high barrier packaging material for herbs and spices are practical objectives of her research. Engineered nano-delivery systems for plant bioactives Develop nano-platforms for targeted delivery and controlled release of plant bioactives including antioxidant and antimicrobial products, through testing of in vitro activities and shelf life under various conditions.
Photodynamic treatment
Photodynamic treatment or photosensitization is a novel light and photo dye based approach which offers promising alternatives to conventional methods for the control of microorganisms. Plant bioactives such as curcumin has been successfully used to control mycrotoxigenic fungi. This technology has potential as a decontamination tool to reduce the microbial load in food and feed.
Food safety
Her research focus in this field includes intervention strategies to inhibit and prevent food-borne pathogens and spoilage organisms in fresh food and beverages, elucidating mechanisms of antimicrobial action, shelf-life extension with natural antimicrobials, retaining bioactivity during processing and storage, search for natural inhibitors from Australian native plants, use of bioactive honey from Leptospermum polygalifolium (Jelly bush) in treating microbial wound infections.
School of Electrical Engineering and Computer Science
Faculty of Engineering, Architecture and Information Technology
Availability:
Available for supervision
Dr Hongfu Sun completed his PhD in Biomedical Engineering at the University of Alberta in 2015, followed by postdoctoral training in Calgary until 2018. He joined the Imaging, Sensing and Biomedical Engineering team in the School of ITEE at UQ in 2019 and was awarded the ARC DECRA fellowship in 2021. His research interests include developing novel magnetic resonance imaging (MRI) contrast mechanisms, e.g. Quantitative Susceptibility Mapping (QSM), fast and multi-parametric MRI acquisitions, and advanced image reconstruction techniques, including deep learning and artificial intelligence, to advance medical imaging techniques for clinical applications.
Dr Sun is currently recruiting graduate students. Check out Available Projects for details. Open to both Domestic and International students.
Affiliate Professor of School of Chemistry and Molecular Biosciences
School of Chemistry and Molecular Biosciences
Faculty of Science
Affiliate of The Centre for Cell Biology of Chronic Disease
Centre for Cell Biology of Chronic Disease
Institute for Molecular Bioscience
NHMRC Leadership Fellow - GL
Institute for Molecular Bioscience
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Available for supervision
Media expert
Matt Sweet is an NHMRC Leadership Fellow, Group Leader, and Director of Higher Degree Research (DHDR) at the Institute for Molecular Bioscience (IMB) at The University of Queensland, Brisbane, Australia. He was the founding Director of the IMB Centre for Inflammation and Disease Research (2014-2018), also serving as Deputy Head of the IMB Division of Cell Biology and Molecular Medicine during this period. Matt studies innate immunity, the body’s danger sensing system that responds to infection, injury and dysregulated homeostasis, and the role of this system in health and disease. Matt’s research team focuses on manipulating the innate immune system for the development of anti-infective and anti-inflammatory strategies. To do so, his lab characterizes the roles of specific innate immune pattern recognition receptors and their downstream signalling pathways/gene products in inflammatory disease processes, as well as in host responses to bacterial pathogens. He has authored >175 journal articles and book chapters, including in Science (2), Science Translational Medicine, Science Immunology, Nature Immunology, Nature Genetics, Nature Communications (4), PNAS USA (6) and Journal of Experimental Medicine (2), and his career publications have accrued >19,000 citations.
Biography
I was awarded a PhD (The University of Queensland) in 1996 for my research under the supervision of Prof David Hume into gene regulation in macrophages, immune cells with important roles in health and disease. I subsequently undertook a short postdoctoral position in the same laboratory, focusing on the activation of macrophages by pathogen products. I then embarked on a CJ Martin post-doctoral training fellowship with Prof Eddy Liew, FRS at the University of Glasgow in Scotland. Returning to The University of Queensland, I had a prominent role within the Cooperative Research Centre for Chronic Inflammatory Diseases (including as UQ node head from 2007-2008) and was appointed as a Group Leader at the IMB in 2007. I have continued fellowship support since this time, including as an ARC Future Fellow, an NHMRC Senior Research Fellow and an NHMRC Leadership Fellow (current, from 2021).
Key discoveries
CpG-containing DNA as an activator of innate immunity, and characterization of the receptor (TLR9) detecting this microbial component.
The IL-1 receptor family member ST2 as a critical regulator of innate immunity and inflammation.
Inflammatory and antimicrobial functions of histone deacetylase enzymes (HDACs) in macrophages.
Effects of the growth factor CSF-1 on inflammatory responses in macrophages.
Mechanisms responsible for divergence in TLR responses between human and mouse macrophages, as well as the functional consequences of such divergence.
TLR-inducible zinc toxicity as an antimicrobial weapon of macrophages and the identification of defects in this pathway in cystic fibrosis.
Host evasion strategies used by the bacterial pathogens Salmonella enterica serovar Typhimurium and uropathogenic E. coli.
SCIMP as a novel TLR adaptor that mediates TLR tyrosine phosphorylation and selective cytokine outputs.
Genes and pathways associated with the severity of chronic liver disease.
Molecular mechanisms controlling macrophage immunometabolism, as well as associated inflammatory and antimicrobial responses.
Anti-inflammatory and antibacterial activities of the metabolite ribulose-5-phosphate.
Research training
I have supervised or co-supervised 29 completed PhD students and 22 completed honours students, as well as 9 post-doctoral researchers. Many of my former staff and students continue to have active research careers around the world (USA, UK, Europe, Australia), including as independent laboratory heads. I currently supervise 5 PhD students in my laboratory, co-supervise 4 PhD students in other laboratories, and oversee the research activities of 2 post-doctoral researchers in my group. Current and former staff/students have received numerous fellowships and awards during their research careers (e.g. ARC DECRA, NHMRC CJ Martin fellowship, UQ post-doctoral fellowship, Smart State scholarship). I have also examined >25 PhD theses in the fields of innate immunity, inflammation and host defence.
Professional activities
I am an editorial board member of the Journal of Leukocyte Biology and Seminars in Cell & Developmental Biology, and have served as an editorial board member for several other journals in the past e.g. Immunology and Cell Biology. I have served on NHMRC project grant review panels in 2007, 2008, 2009, 2012 (as panel chair) and 2014, NHMRC Ideas panels in 2020 and 2024, NHMRC Investigator panels in 2021 and 2022, as well as a member of the NHMRC RGMS user reference group committee from 2010-2012. I acted as national representative for the Australasian Society of Immunology (ASI) Infection and Immunity special interest group from 2012-2017. At UQ, I served as chair of an animal ethics committee from 2013-2014, and co-organized the UQ Host-Pathogen interaction network from 2007-2010 (prior to the establishment of the Australian Infectious Diseases Research Centre). I am currently Director of Higher Degree by Research at IMB, overseeing HDR student recruitment and training.
I have made extensive contributions to conference organization in my discipline. I co-organized the national TLROZ2009 and TLROZ2012 conferences, I organized the first ever Australasian Society for Immunology (ASI) Infection and Immunity workshop (2009), was chair of the ASI Program Committee and co-organizer of the Infection and Immunity workshop for ASI2017, and I co-organized the annual IMB Inflammation Symposium (2014-2018). I also co-chaired the 2019 World Conference of Inflammation (Sydney, September 2019). In addition, I have been a member of the organizing committee for ASI2009, the 2014 International Cytokine and Interferon Society conference, the Lorne Infection and Immunity conference (2014-2020), and the Brisbane Immunology Group annual meeting (2008 to the present).
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Available for supervision
Tim is a clinical pharmacist and conjoint lecturer working at the School of Pharmacy and the Princess Alexandra Hospital. He graduated from the Bachelor of Pharmacy at the University of Queensland in 2014. After working in mental health at the Princess Alexandra Hospital, he become interested in schizophrenia and psychopharmacology. He began his PhD with the School of Clinical Medicine in 2020 and his research interests include clozapine, treatment refractory schizophrenia, and the safe use of antipsychotic medicines. He is the team leader of mental health pharmacy at the Princess Alexandra Hospital. Tim teaches into the Bachelor of Pharmacy and the Masters of Clinical Pharmacy programs at the University of Queensland, and supervises research project placements.
Faculty of Health, Medicine and Behavioural Sciences
Affiliate of Centre for Cardiovascular Health and Research
Centre for Cardiovascular Health and Research
Faculty of Health, Medicine and Behavioural Sciences
Centre Director of Centre for Research on Exercise, Physical Activity and Health
Centre for Research on Exercise, Physical Activity and Health
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Available for supervision
Media expert
Dr Jenna L. Taylor obtained her PhD in Exercise Physiology from The University of Queensland in 2019 as an NHMRC postgraduate research scholar. She then completed a 3-year postdoctoral research fellowship in the United States at The Mayo Clinic with the Department of Cardiovascular Medicine. She is now a Lecturer in Clinical Exercise Physiology with the School of Human Movement and Nutrition Sciences at UQ and heads up the Physiology and Ultrasound Laboratory for Science and Exercise (PULSE). Her interest in cardiovascular disease stems from her clinical experience as an exercise physiologist and dietitian working in a hospital-based cardiac rehabilitation program. Broadly, her research interests involve the effect of exercise training and intensity on improving cardiovascular and brain health, in the settings of healthy ageing and risk reduction for cardiovascular disease and vascular dementia. She is currently the PI on an NIH-funded Clinical Trial (1R21AG073726) investigating the influence of exercise training and intensity on cognitive function and cerebral blood flow regulation in patients with cardiovascular disease.
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Available for supervision
Wubshet is an accredited pharmacist, lecturer, and Mental Health First Aid Instructor at the University of Queensland’s Faculty of Health and Behavioural Sciences. He also holds an Affiliate Research Fellow position at the University of Sydney School of Pharmacy. Currently, he is a course coordinator for Pharmacy Practice and Medicines Management in the BPharm (Hons) program.
He completed his PhD at the University of Tasmania in 2019. Following that, he held postdoctoral researcher roles at the University of Canberra and University of Sydney, where he coordinated multiple government- and industry-funded clinical trials.
Wubshet's research primarily centres around understanding medication and patient outcomes in individuals with chronic diseases, with a special emphasis on kidney diseases. In collaboration with several researchers and stakeholders in Australia, Wubshet has attracted ~$2.1 million in grant funding. Currently, he is actively involved as an investigator in a large-scale cluster randomised trial (ACTRN12622000329763) funded by the Medical Research Future Fund and led by the University of Sydney. This trial is investigating the effectiveness of a community pharmacy-led point-of-care screening in improving the detection of chronic kidney disease and quality use of medicines.
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Available for supervision
Media expert
Professor Susan Tett is a registered pharmacist with research interests in Quality Use of Medicines (improving how medicines are used) and clinical pharmacokinetics (optimising medicine doses)
Sue completed her PhD in 1988. Since this time she has been in research positions and in academia at Sydney University, St Vincent’s Hospital, Sydney and at the University of Queensland. She has over 150 peer reviewed research publications and over 200 conference presentations and is on Editorial Board of Clinical Pharmacokinetics. Sue was Head of the School of Pharmacy, University of Queensland 1996-2004 and Deputy Executive Dean & Associate Dean Research for the Faculty of Health Sciences 2006-2010, including periods as Acting Executive Dean.
Susan Tett has been a member of many Australian national and State advisory committees, including Pharmaceutical Health and Rational use of Medicines Committee 1996-2004, Pharmaceutical Sub-Committee of the Australian Drug Evaluation Committee 1995-2004, Pharmaceutical Industry Working Group 2003-10 , Pharmaceutical Partnerships Program Committee of the Industry Research & Development Board 2003-09, and has participated in NHMRC Project Grant Review Panels and Fellowships Panels. She was also Councillor for the Pharmaceutical Society of Australia (Queensland Branch) and was the Australian Pharmacist of the Year in 1999, for her contributions to pharmacy education and research.
Sue’s research interests are directed towards optimising the clinical use of medications. General areas of research include quality use of medicines, clinical pharmacokinetics and pharmacodynamics. Sue supervises a number of postgraduate students and is actively involved in innovation in the pharmacy profession, pushing the professional boundaries. She is committed to enhancing the role of the health care team in optimising consumer health outcomes.
Faculty of Health, Medicine and Behavioural Sciences
Senior Research Fellow
General Practice Clinical Unit
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Available for supervision
Dr Hayley Thomas is a General Practitioner who works clinically on the north side of Brisbane, and academically as a clinical senior lecturer with the General Practice Clinical Unit. She is currently the academic co-coordinator for the General Practice course in the MD program. Hayley's research interests include whole person care and the GP-Patient relationship.
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Available for supervision
Media expert
Professor Thomas’ research is focused on the study of the biology and clinical use of human dendritic cells in autoimmune disease. It has explored basic mechanisms of immunity and dendritic cell function in autoimmune disease.
Professor Thomas is a graduate of the University of Western Australia. She received her MBBS in 1984, and then trained in Perth as a rheumatologist. She commenced a research fellowship with Peter Lipsky at Southwestern Medical Center, University of Texas in 1990, where she first identified and characterised human circulating dendritic cell precursors. She is now Professor of Rheumatology at The University of Queensland's Frazer Institute, Translational Research Institute, consultant Rheumatologist at Princess Alexandra Hospital and fellow of the Australian Academy of Health and Medical Sciences. In 2020 she was awarded Member of the Order of Australia. She has founded two spin-off companies Dendright (2006-2021), and Liperate in 2022.
Her research seeks to understand autoimmune disease and restoration of immune tolerance. Through this work, she developed dendritic cell-based citrullinated antigen-specific immunotherapy in the first proof-of-concept trial in Rheumatoid Arthritis. She then developed a liposome immunotherapy that targets dendritic cells to induce antigen-specific tolerance, opening new opportunities for the control and prevention of autoimmune disease. Dendright progressed a liposome-based tolerance strategy for rheumatoid arthritis to a phase I trial, and Liperate is planning to open a trial of a liposome-based tolerance strategy for type 1 diabetes in 2024. She has contributed major insights into immune tolerance mechanisms and interaction between microbiome and the immune system to trigger or control spondyloarthropathy.
Centre Director of Queensland Alliance for Environmental Health Science
Queensland Alliance for Environmental Health Sciences
Faculty of Health, Medicine and Behavioural Sciences
Centre Director of Minderoo Centre for Plastics and Human Health
Minderoo Centre for Plastics and Human Health
Faculty of Health, Medicine and Behavioural Sciences
Affiliate of ARC Training Centre for Bioplastics and Biocomposites
ARC Training Centre for Bioplastics and Biocomposites
Faculty of Engineering, Architecture and Information Technology
Affiliate of Centre for Marine Science
Centre for Marine Science
Faculty of Science
Centre Director - QAEHS
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Available for supervision
Media expert
Professor Kevin Thomas is Director of the Queensland Alliance for Environmental Health Sciences (QAEHS). Kevin is an environmental health scientist with a particular interest in understanding the environmental exposures associated with contaminants of emerging concern (CECs) with the goal of protecting environmental and human health. Kevin also leads the Minderoo Centre- Plastics and Human Health at UQ and is Deputy-Director of the Australian Research Council Industrial Transformation Training Centre for Hyphenated Analytical Separation Technologies (HyTech).
His current research is focused on understanding human exposure to plastics pollution and developing mass spectrometric analytical methods for characterizing plastics and other CECs, assessing community-wide health status through analysing wastewater (wastewater-based epidemiology) and establishing alternative approaches to exposure monitoring, for example explanted silicone prostheses and wristbands.
Author of over 300 peer-reviewed papers and Associate Editor for the journal Science of the Total Environment, Kevin is a strong collaborative researcher having founded the international SCORE network on sewer biomarker analysis for community health assessment (see www.score-network.eu) and together with colleagues has recently launched InSpectra- A platform for identifying emerging chemical threats.
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Available for supervision
Media expert
Professor Rachel Thomson is a Head of the Greenslopes Clinical Unit, Thoracic Physician and clinical researcher working at Greenslopes Private Hospital.
She has an international reputation in the area of Pulmonary Nontuberculous mycobacterial disease. She has published widely in the area and is regularly invited to speak at international and national meetings.https://medical-school.uq.edu.au/research/ntm-research-group
Her current research focuses on immunological and environmental aspects of susceptibility to NTM infection, characteristics of the lung and gut microbiome in NTM, and improving treatment outcomes.
In a clinical capacity, Professor Thomson is able to offer patients expert management of their disease at Pulmedica, Greenslopes Private Hospital, at public clinics at The Prince Charles Hospital and the MetroSouth Clinical TB service of the Princess Alexandra Hospital and via telehealth for patients across Australia. Patients can also access novel treatments through clinical trials in both the private and public sector.
Prof Thomson also has a special interest in respiratory problems of the elite athlete. This includes asthma management, vocal cord dysfunction, and the requirements of national and international doping organisations for asthma medications.
Affiliate of ARC COE for Children and Families Over the Lifecourse
ARC COE for Children and Families Over the Lifecourse
Faculty of Humanities, Arts and Social Sciences
Affiliate of Child Health Research Centre
Child Health Research Centre
Faculty of Health, Medicine and Behavioural Sciences
ARC Australian Laureate Fellow - Group Leader
Queensland Brain Institute
Faculty of Health, Medicine and Behavioural Sciences
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Available for supervision
Media expert
Karen Thorpe is Australian Research Council, Laureate Professor and Group Leader in Child Development, Education and Care at the Queensland Brain Institute, University of Queensland. Her research is grounded in the understanding that early learning experiences shape brain development and are critical in establishing trajectories of health, social inclusion and learning across the lifespan. A particular focus of her work is early care and education environments including parenting, parent work, quality of care and education, and the early years workforce.
Karen leads a multi-disciplinary team of developmental scientists undertaking large scale longitudinal studies with embedded studies to explicate mechanisms that enable or limit children’s life chances. She was Foundation Psychologist on the Avon Longitudinal Study of Parents and Children at the University of Bristol, UK; led the evaluation of the Preparing School Trial for Queensland Government; led the Queensland team of the E4Kids study of quality in Australian Early Education and Care and a recent data linkage project with Queensland Government to track participants through their school journey. In partnership with Queensland Government, Goodstart Early Learning and the Creche and Kindergarten Association she led a large population study of the Australian ECEC workforce (ARC Linkage). Her current research, as a chief investigator on the ARC Centre of Excellence for Children and Families across the life course, and through an ARC Laureate fellowship, is to examine barriers to providing high quality early learning services in developmentally vulnerable communities.
In 2013 and again in 2019 Karen was named by the Australian Financial Review as among Australia's 100 Women of Influence for the impacts of her research on educational and family policy. In 2020 she was recognised by Australian Government, Advance Global Awards for her international contribution to education. Karen chairs the Australian Early Years Reference Council for Evidence for Learning, Australia whose remit is to build a strong evidence-base in early childhood education and care with focus on translation into policy and practice. She is also director on the board of the Australian Research Council for Children and Youth and advisor to the national board of Beyond Blue – Be You.
Faculty of Health, Medicine and Behavioural Sciences
ATH - Lecturer
PA Southside Clinical Unit
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Not available for supervision
I graduated in 2013 with a MBBS from the University of Queensland. Currently, I work as a Junior Registrar in General Surgery (Pre-training position) at the Logan Hospital in Queensland, Australia. I love teaching medical students and involve myself in meaningful research during my spare time.
I am committed to practicing evidence based, safe and honest medicine in the field of Surgery.
Affiliate of Australian Women's and Girls' Health Research Centre
Australian Women's and Girls' Health Research Centre
Faculty of Health, Medicine and Behavioural Sciences
Principal Research Fellow
School of Public Health
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Not available for supervision
Media expert
A/Prof Leigh Tooth is a Principal Research Fellow who specialises in research on maternal and child health and general women's health, in particular on women carers, health inequalities and the socio-economic determinants of health, quality of life and comorbidity.
A/Prof Leigh Tooth is currently Principal Research Fellow and Deputy Director of the Australian Longitudinal Study on Women's Health (ALSWH). She chairs the Data Access Committee of the ALSWH. She is CI on the NHMRC funded Centre for Research Excellence on Women and Non-communicable Disease (CRE WaND): Prevention and Detection (2019–2024). She was CI on the NHMRC funded Mothers and their Children’s Health Study (MatCH) (2014-2018). MatCH is investigating the relationship between mothers’ health history, since 1996, and the family environment to children’s health and development outcomes, including health service utilisation. She is also leading a program of research into health inequalities and the socio-economic determinants of health, and women carers. Her other current research interests are quality of life and comorbidity. Her previous research experiences include a NHMRC Public Health Fellowship (1999-2003), during which she investigated the short and long term functional and community outcomes of people following stroke, and being a NHMRC Fellow with the Longitudinal Studies Unit in the School of Public Health at the University of Queensland researching statistical methodology and teaching into the epidemiology program. She has a PhD and first class honours degree in Occupational Therapy from the University of Queensland.
Affiliate of Centre for Extracellular Vesicle Nanomedicine
Centre for Extracellular Vesicle Nanomedicine
Faculty of Health, Medicine and Behavioural Sciences
Affiliate Research Fellow of School of Biomedical Sciences
School of Biomedical Sciences
Faculty of Health, Medicine and Behavioural Sciences
Research Fellow
Australian Institute for Bioengineering and Nanotechnology
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Available for supervision
Dr Tosolini is a cell biologist with a focus at the intersection of axonal transport, neurotrophic factors, motor neurons and skeletal muscle, in the context of motor neuron disease (MND)/amyotrophic lateral sclerosis (ALS). His research to date has focused on utilising the connectivity between skeletal muscle and motor neurons for the enhanced delivery of therapeutic agents to the spinal cord (e.g., viral-mediated gene therapy). Building upon these foundations, his postdoctoral training focused on defining the axonal transport dynamics in a number of different experimental conditions, including stimulation with different neurotrophic factors (e.g., BDNF, GDNF), α motor neuron subtypes (i.e., fast motor neurons vs slow motor neurons), and alterations to such factors in MND/ALS pathology.
Dr Tosolini has joined the laboratories of A/Prof. Shyuan Ngo (AIBN) and Dr. Derek Steyn (SBMS) to undertake a novel project looking at assessing a novel therapeutic compound in mouse models of ALS, and in as well as in ALS patient-derived muscle cultures. This project is in collaboration with Dr. Giovanni Nardo at Laboratory of Molecular Neurobiology, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Dr Tosolini completed his PhD in 2015 in the discipline of Anatomy at the School of Medical Sciences, University of New South Wales (UNSW). His PhD project focused on characterising the connectivity between various skeletal muscles and their innervating motor neuron pools, to optimally deliver agents (e.g., retrograde tracers, virus) to the spinal cord motor neurons via retrograde axonal transport. For the work produced in his PhD, Dr Tosolini was awarded a place on the Faculty of Medicine's Dean's List.
In 2016, Dr Tosolini joined the Schiavo Laboratory at University College London (UCL), UK as a Post-Doctoral Research Associate to undertake a project focused on: 1) understanding factors influencing axonal transport dynamics in distinct in vitro and in vivo models of motor neuron disease (MND)/amyotrophic lateral sclerosis (ALS), and 2) revealing the signalling elements governing neuronal trans-synaptic transfer.
In 2020, Dr Tosolini was awarded a Junior Non-Clinical Post-Doctoral Fellowship by the Motor Neuron Disease Association, UK to expand his work on evaluating axonal transport dynamics in mouse models of motor neuron disease (MND) as well as in diverse human induced pluripotent stem cell (hiPSC)-derived motor neurons. This project is a direct continuation of my post-doctoral training in the Schiavo laboratory, and included a novel collaboration with Prof. Rickie Patani (Francis Crick Institute, London, UK), to evaluate axonal transport dynamics of diverse organelles in mouse and human models of MND/ALS.
Faculty of Health, Medicine and Behavioural Sciences
Availability:
Available for supervision
Marion has several years teaching and learning and leadership experience in the higher education sector. She is also a Board Director for Metro South Hospital and Health Services and Chairs the Metro South Safety & Quality committee. She is also a Council member of a local school. Marion completed a Bachelor of Nursing (Hons) in Sydney and then worked across NSW, Vic and QLD with experience in critical care and acute medical surgical areas, specialising in cardiology and emergency nursing. She completed a Master of Nursing in Women’s Health through QUT and a PhD at Griffith University. Marion has broad experience is leading curriculum design, implementation and review and has been involved in numerous research projects around students’ experiences of university and supporting and assessing students’ learning. Her research interests include nurse education, the student experience of university, assessment of learning, supporting casual academic staff and clinical decision making in practice. Marion also supervises several PhD students across a range of interests and research methodologies.