Professor

Wally Thomas

Email: 
Phone: 
+61 7 336 51074

Availability

Professor Wally Thomas is:
Available for supervision
Media expert

Fields of research

Biological Sciences Cardiovascular medicine and haematology Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Science, The University of Queensland
  • Bachelor (Honours) of Science (Advanced), The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Search Professor Wally Thomas’s works on UQ eSpace

173 works between 1985 and 2024
All (173) Journal Article (139) Book Chapter (4) Conference Publication (30)

1 - 20 of 173 works

2024

Conference Publication

Targeting Cardiomyocytes with Adeno Associated Viruses to Protect Hearts from Trastuzumab-induced Cardiotoxicity

Reichelt, Melissa, Ho, Uda, Bunt, Kelsey, Watson, Sophie, Patel, Kinjal, Bradford, Julia and Thomas, Walter G. (2024). Targeting Cardiomyocytes with Adeno Associated Viruses to Protect Hearts from Trastuzumab-induced Cardiotoxicity. American Physiology Summit 2024, Long Beach, CA United States, 4-7 April 2024. Rockville, MD United States: American Physiological Society. doi: 10.1152/physiol.2024.39.s1.2480

Targeting Cardiomyocytes with Adeno Associated Viruses to Protect Hearts from Trastuzumab-induced Cardiotoxicity

2024

Journal Article

Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction

Redd, Meredith A, Yoshikawa, Yusuke, Khan, Nemat, Waqar, Maleeha, Saez, Natalie J, Outhwaite, Jennifer E, Russell, Jake S, Hanna, Amy D, Chiu, Han S, Er, Sing Yan, Butcher, Neville J, Mardon, Karine, Fraser, John F, Smythe, Mark L, Rash, Lachlan D, Thomas, Walter G, King, Glenn F, Reichelt, Melissa E and Palpant, Nathan J (2024). Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction. European Heart Journal, 45 (17), 1571-1574. doi: 10.1093/eurheartj/ehad793

Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction

2024

Journal Article

Cardiac human bitter taste receptors contain naturally occurring variants that alter function

Bloxham, Conor J., Hulme, Katina D., Fierro, Fabrizio, Fercher, Christian, Pegg, Cassandra L., O'Brien, Shannon L., Foster, Simon R., Short, Kirsty R., Furness, Sebastian G. B., Reichelt, Melissa E., Niv, Masha Y. and Thomas, Walter G. (2024). Cardiac human bitter taste receptors contain naturally occurring variants that alter function. Biochemical Pharmacology, 219 115932, 115932. doi: 10.1016/j.bcp.2023.115932

Cardiac human bitter taste receptors contain naturally occurring variants that alter function

2023

Journal Article

Angiotensin receptors in GtoPdb v.2023.1

Alexander, Wayne, Bernstein, Kenneth E., Catt, Kevin J., De Gasparo, Marc, Dhanachandra Singh, Khuraijam, Eguchi, Satoru, Escher, Emanuel, Goodfriend, Theodore L., Horiuchi, Mastgugu, Hunyady, László, Husain, Ahsan, Inagami, Tadashi, Karnik, Sadashiva, Kemp, Jacqueline, Thomas, Walter G., Timmermans, Pieter B. M. W. M., Tirupula, Kalyan, Unal, Hamiyet, Unger, Thomas and Vanderheyden, Patrick (2023). Angiotensin receptors in GtoPdb v.2023.1. IUPHAR/BPS Guide to Pharmacology CITE, 2023 (1), 1-21. doi: 10.2218/gtopdb/f6/2023.1

Angiotensin receptors in GtoPdb v.2023.1

2023

Journal Article

Early cardiac aging linked to impaired stress-resistance and transcriptional control of stress response, quality control and mitochondrial pathways

Ashton, Kevin J., Kiessling, Can J., Thompson, Jamie-Lee M., Aziz, Aliah Y., Thomas, Walter G., Headrick, John P. and Reichelt, Melissa E. (2023). Early cardiac aging linked to impaired stress-resistance and transcriptional control of stress response, quality control and mitochondrial pathways. Experimental Gerontology, 171 112011, 1-15. doi: 10.1016/j.exger.2022.112011

Early cardiac aging linked to impaired stress-resistance and transcriptional control of stress response, quality control and mitochondrial pathways

2023

Conference Publication

A bitter taste in your heart: cardiac cells expressing T2Rs and polymorhpisms that affect cardiac function

Thomas, Walter G., Bloxham, Conor J., Dashwood, Alexander, Cheesman, Elizabeth, Hulme, Katina D., Khoo, Hui Y., Russell, Jake D., Yoshikawa, Yusuke, Reichelt, Melissa E., Short, Kirsty R., Furness, Sebastian B. G., Foster, Simon R. and Molenaar, Peter (2023). A bitter taste in your heart: cardiac cells expressing T2Rs and polymorhpisms that affect cardiac function. 45th Annual Meeting of the Association-for-Chemoreception-Sciences, Bonita Springs, FL, United States, 19-22 April 2023. Oxford, United Kingdom: Oxford University Press.

A bitter taste in your heart: cardiac cells expressing T2Rs and polymorhpisms that affect cardiac function

2022

Journal Article

Akt acts as a switch for GPCR transactivation of the TGF‐β receptor type 1

Mohamed, Raafat, Shajimoon, Aravindra, Afroz, Rizwana, Gabr, Mai, Thomas, Wally, Little, Peter J. and Kamato, Danielle (2022). Akt acts as a switch for GPCR transactivation of the TGF‐β receptor type 1. The FEBS Journal, 289 (9), 2642-2656. doi: 10.1111/febs.16297

Akt acts as a switch for GPCR transactivation of the TGF‐β receptor type 1

2022

Journal Article

A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals

Eagles, David A., Saez, Natalie J., Krishnarjuna, Bankala, Bradford, Julia J., Chin, Yanni K.-Y., Starobova, Hana, Mueller, Alexander, Reichelt, Melissa E., Undheim, Eivind A. B., Norton, Raymond S., Thomas, Walter G., Vetter, Irina, King, Glenn F. and Robinson, Samuel D. (2022). A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals. Proceedings of the National Academy of Sciences, 119 (7) e2112630119. doi: 10.1073/pnas.2112630119

A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals

2021

Journal Article

Corrigendum to “BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes” [Biochem. Pharmacol. 158 (2108) 232–242] (Biochemical Pharmacology (2018) 158 (232–242), (S0006295218304386), (10.1016/j.bcp.2018.10.017))

O'Brien, Shannon L., Johnstone, Elizabeth K.M., Devost, Dominic, Conroy, Jacinta, Reichelt, Melissa E., Purdue, Brooke W., Ayoub, Mohammed A., Kawai, Tatsuo, Inoue, Asuka, Eguchi, Satoru, Hébert, Terence E., Pfleger, Kevin D.G. and Thomas, Walter G. (2021). Corrigendum to “BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes” [Biochem. Pharmacol. 158 (2108) 232–242] (Biochemical Pharmacology (2018) 158 (232–242), (S0006295218304386), (10.1016/j.bcp.2018.10.017)). Biochemical Pharmacology, 192 114756, 114756. doi: 10.1016/j.bcp.2021.114756

Corrigendum to “BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes” [Biochem. Pharmacol. 158 (2108) 232–242] (Biochemical Pharmacology (2018) 158 (232–242), (S0006295218304386), (10.1016/j.bcp.2018.10.017))

2021

Journal Article

Therapeutic inhibition of acid sensing ion channel 1a recovers heart function after ischemia-reperfusion injury

Redd, Meredith A., Scheuer, Sarah E., Saez, Natalie J., Yoshikawa, Yusuke, Chiu, Han Sheng, Gao, Ling, Hicks, Mark, Villanueva, Jeanette E., Joshi, Yashutosh, Chow, Chun Yuen, Cuellar-Partida, Gabriel, Peart, Jason N., See Hoe, Louise E., Chen, Xiaoli, Sun, Yuliangzi, Suen, Jacky Y., Hatch, Robert J., Rollo, Ben, Xiao, Di, Alzubaidi, Mubarak A.H., Maljevic, Snezana, Quaife-Ryan, Gregory A., Hudson, James E., Porrello, Enzo R., White, Melanie Y., Cordwell, Stuart J., Fraser, John F., Petrou, Steven, Reichelt, Melissa E. ... Palpant, Nathan J. (2021). Therapeutic inhibition of acid sensing ion channel 1a recovers heart function after ischemia-reperfusion injury. Circulation, 144 (12), 947-960. doi: 10.1161/circulationaha.121.054360

Therapeutic inhibition of acid sensing ion channel 1a recovers heart function after ischemia-reperfusion injury

2021

Journal Article

The concise guide to pharmacology 2021/22: G protein‐coupled receptors

Alexander, Stephen PH, Christopoulos, Arthur, Davenport, Anthony P, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Abbracchio, Maria Pia, Alexander, Wayne, Al‐hosaini, Khaled, Bäck, Magnus, Barnes, Nicholas M., Bathgate, Ross, Beaulieu, Jean‐Martin, Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel J.M., Blaho, Victoria, Boulay, Francois, Bousquet, Corinne, Bräuner‐Osborne, Hans, Burnstock, Geoffrey, Caló, Girolamo ... Ye, Richard D. (2021). The concise guide to pharmacology 2021/22: G protein‐coupled receptors. British Journal of Pharmacology, 178 (S1), S27-S156. doi: 10.1111/bph.15538

The concise guide to pharmacology 2021/22: G protein‐coupled receptors

2021

Journal Article

Type I diabetes mellitus increases the cardiovascular complications of influenza virus infection

Sinclair, Jane E., Bloxham, Conor J., Chiu, Han, Chew, Keng Yih, Russell, Jake, Yoshikawa, Yusuke, Bielefeldt-Ohmann, Helle, Steele, Lauren E., Hulme, Katina D., Verzele, Nathalie A. J., Noye, Ellesandra C., Wu, Melanie, Reichelt, Melissa E., Thomas, Walter G., Gallo, Linda A., Redd, Meredith A. and Short, Kirsty R. (2021). Type I diabetes mellitus increases the cardiovascular complications of influenza virus infection. Frontiers in Cellular and Infection Microbiology, 11 714440, 714440. doi: 10.3389/fcimb.2021.714440

Type I diabetes mellitus increases the cardiovascular complications of influenza virus infection

2021

Journal Article

Stimulation of the four isoforms of receptor tyrosine kinase ErbB4, but not ErbB1, confers cardiomyocyte hypertrophy

Wang, Zhen, Chan, Hsiu‐Wen, Gambarotta, Giovanna, Smith, Nicola J., Purdue, Brooke W., Pennisi, David J., Porrello, Enzo R., O'Brien, Shannon L., Reichelt, Melissa E., Thomas, Walter G. and Paravicini, Tamara M. (2021). Stimulation of the four isoforms of receptor tyrosine kinase ErbB4, but not ErbB1, confers cardiomyocyte hypertrophy. Journal of Cellular Physiology, 236 (12) jcp.30487, 8160-8170. doi: 10.1002/jcp.30487

Stimulation of the four isoforms of receptor tyrosine kinase ErbB4, but not ErbB1, confers cardiomyocyte hypertrophy

2021

Journal Article

Complex interactions between the angiotensin II type 1 receptor, the epidermal growth factor receptor and TRIO-dependent signaling partners

Johnstone, Elizabeth K.M., Abhayawardana, Rekhati S., See, Heng B., Seeber, Ruth M., O'Brien, Shannon L., Thomas, Walter G. and Pfleger, Kevin D.G. (2021). Complex interactions between the angiotensin II type 1 receptor, the epidermal growth factor receptor and TRIO-dependent signaling partners. Biochemical Pharmacology, 188 114521, 1-16. doi: 10.1016/j.bcp.2021.114521

Complex interactions between the angiotensin II type 1 receptor, the epidermal growth factor receptor and TRIO-dependent signaling partners

2020

Journal Article

Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies

Gormal, Rachel S., Padmanabhan, Pranesh, Kasula, Ravikiran, Bademosi, Adekunle T., Coakley, Sean, Giacomotto, Jean, Blum, Ailisa, Joensuu, Merja, Wallis, Tristan P., Lo, Harriet P., Budnar, Srikanth, Rae, James, Ferguson, Charles, Bastiani, Michele, Thomas, Walter G., Pardon, Els, Steyaert, Jan, Yap, Alpha S., Goodhill, Geoffrey J., Hilliard, Massimo A., Parton, Robert G. and Meunier, Frédéric A. (2020). Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies. Proceedings of the National Academy of Sciences of the United States of America, 117 (48), 30476-30487. doi: 10.1073/pnas.2007443117

Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies

2020

Journal Article

A high fat diet increases influenza A virus-associated cardiovascular damage

Siegers, Jurre Y., Novakovic, Boris, Hulme, Katina D., Marshall, Rebecca, Bloxham, Conor J., Thomas, Walter G., Reichelt, Mellissa E., Leijten, Lonneke, van Run, Peter, Knox, Karen, Sokolowski, Kamil A., Tse, Brian W. C., Chew, Keng Yih, Christ, Angelika N., Howe, Greg, Bruxner, Timothy J. C., Karolyi, Mario, Pawelka, Erich, Koch, Rebecca M., Bellmann-Weiler, Rosa, Burkert, Francesco, Weiss, Günter, Samanta, Romit J., Openshaw, Peter J. M., Bielefeldt-Ohmann, Helle, van Riel, Debby and Short, Kirsty R. (2020). A high fat diet increases influenza A virus-associated cardiovascular damage. The Journal of infectious diseases, 222 (5), 820-831. doi: 10.1093/infdis/jiaa159

A high fat diet increases influenza A virus-associated cardiovascular damage

2020

Journal Article

A bitter taste in your heart

Bloxham, Conor J., Foster, Simon R. and Thomas, Walter G. (2020). A bitter taste in your heart. Frontiers in Physiology, 11 431, 431. doi: 10.3389/fphys.2020.00431

A bitter taste in your heart

2020

Conference Publication

Naturally occurring, non-functional polymorphisms in cardiac T2R (bitter taste) receptors

Bloxham, Conor, Foster, Simon and Thomas, Walter (2020). Naturally occurring, non-functional polymorphisms in cardiac T2R (bitter taste) receptors. 29th Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Trieste, Italy, 11-14 September 2019. Oxford, United Kingdom: Oxford University Press.

Naturally occurring, non-functional polymorphisms in cardiac T2R (bitter taste) receptors

2019

Journal Article

The Concise Guide to Pharmacology 2019/20: G protein‐coupled receptors

Alexander, Stephen P. H., Christopoulos, Arthur, Davenport, Anthony P., Kelly, Eamonn, Mathie, Alistair, Peters, John A., Veale, Emma L., Armstrong, Jane F., Faccenda, Elena, Harding, Simon D., Pawson, Adam J., Sharman, Joanna L., Southan, Christopher, Davies, Jamie A., Abbracchio, Maria P., Alexander, Wayne, Al-hosaini, Khaled, Bäck, Magnus, Beaulieu, Jean‐Martin, Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel J.M., Blaho, Victoria, Bousquet, Corinne, Bräuner-Osborne, Hans, Burnstock, Geoffrey, Caló, Girolamo, Castaño, Justo P., Catt, Kevin J. ... Yao, Chengcan (2019). The Concise Guide to Pharmacology 2019/20: G protein‐coupled receptors. British Journal of Pharmacology, 176 (S1), S21-S141. doi: 10.1111/bph.14748

The Concise Guide to Pharmacology 2019/20: G protein‐coupled receptors

2019

Conference Publication

Cardiomyocyte ErbB4 receptors are essential for developmental cardiac hypertrophy and cardiac function in adult hearts

Reichelt, M., Wang, Z., Thorn, C., Paravicini, T. and Thomas, W. G. (2019). Cardiomyocyte ErbB4 receptors are essential for developmental cardiac hypertrophy and cardiac function in adult hearts. ESC Congress / World Congress of Cardiology, Paris, France, 31 August - 4 September 2019. Oxford, United Kingdom: Oxford University Press.

Cardiomyocyte ErbB4 receptors are essential for developmental cardiac hypertrophy and cardiac function in adult hearts

Current funding

  • 2023 - 2025
    Protecting hearts from trastuzumab-induced cardiomyopathy
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2023 - 2024
    Studying the basis of and developing new therapies to treat heart disease
    IPF Healthy - Medical Research
    Open grant
  • 2022 - 2024
    Targeting cavin-1 via gene therapy in a model of metabolic/low-level chronic stress
    Diabetes Australia Research Program
    Open grant
  • 2020 - 2023
    Understanding how an old heart gets stiff
    ARC Discovery Projects
    Open grant
  • 2019 - 2022
    How tissues generate the peptide hormone angiotensin II
    ARC Discovery Projects
    Open grant
  • 2019
    Vevo 3100 Imaging System for ultrahigh resolution and frame rate echocardiographic assessment of small animals.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017 - 2018
    A potential role for C5a antagonism in the medical management of feline hypertrophic cardiornyopathy
    Peter & Mary Ellen Stone Memorial Fund
    Open grant
  • 2017 - 2018
    A Pharmacology Screening Facility to Accelerate Drug Discovery and Development
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015
    A state-of-the-art spinning disc confocal microscope for high speed imaging of live cells and super resolution microscopy
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2017
    New mediators of GPCR-growth factor receptor transactivation
    NHMRC Project Grant
    Open grant
  • 2015 - 2017
    PIPS regulate the type 1 angiotensin receptor (NHMRC Project Grant administered by Monash University)
    Monash University
    Open grant
  • 2014 - 2016
    Dietary Na reduction, food hedonism and hypertension
    UQ Collaboration and Industry Engagement Fund - Seed Research Grant
    Open grant
  • 2014
    Establishment of a small animal surgical suite for integrative physiology.
    Open grant
  • 2014
    Mitochondrial analysis suite
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013
    Establishment of an Integrated Facility for Single Cell Analysis
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012
    Establishment of Integrated Small Animal Metabolic and Physiology Assessment Facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012
    Examining vascular structure and function using pressurised myography
    NHMRC Equipment Grant
    Open grant
  • 2012 - 2016
    Manipulating store-operated Ca2+ entry to improve muscle function in dystrophy
    NHMRC Project Grant
    Open grant
  • 2012 - 2014
    Mechanism of Epidermal Growth Factor Receptor Transactivation
    NHMRC Project Grant
    Open grant
  • 2011
    A Multi-Channel Fluorescence Plate Reader for Studying Receptor-Ligand Interactions
    NHMRC Equipment Grant
    Open grant
  • 2011 - 2013
    Role of extracellular surface residues in agonist activation of the alpha1 adrenoceptor
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    Improving muscle function in dystrophy
    UQ Collaboration and Industry Engagement Fund
    Open grant
  • 2010
    Dual channel electrophysiological recordings
    NHMRC Equipment Grant
    Open grant
  • 2010
    High content imaging analysis for bioactive and novel therapeutic target evaluation
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2012
    Molecular regulation of angiotensin receptors
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    Unravelling the sub-nuclear complexity of the brain (ARC Discovery Project administered by the University of Melbourne)
    University of Melbourne
    Open grant
  • 2009
    "Real Time PCR Facility for Biomedical Researchers"
    UQ School/Centre Co-Funding
    Open grant
  • 2009
    Establishment of a rodent cardiovascular and metabolic phenotyping platform
    UQ School/Centre Co-Funding
    Open grant
  • 2009
    Liquid Scintillation Spectroscopy Facility
    UQ School/Centre Co-Funding
    Open grant
  • 2008 - 2010
    NHMRC Senior Research Fellowship B
    NHMRC Research Fellowship
    Open grant
  • 2008 - 2010
    EGFR transactivation in cardiac hypertrophy
    NHMRC Project Grant
    Open grant
  • 2008 - 2009
    Molecular regulation of the type 1 angiotensin receptor
    NHMRC Project Grant
    Open grant
  • 2008 - 2010
    Regulation of Cardiac Hypertrophy (NHMRC grant administered by the University of Melbourne)
    Peter MacCallum Cancer Centre
    Open grant
  • 2008
    Understanding cell physiology by confocal laser scanning microscopy
    UQ Major Equipment and Infrastructure
    Open grant

Availability

Professor Wally Thomas is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    The role of neuregulin in cardiac function and failure

    Principal Advisor

    Other advisors: Dr Melissa Reichelt

  • Doctor Philosophy

    Epidermal growth factor receptors in cardiac function and disease

    Principal Advisor

    Other advisors: Dr Melissa Reichelt

  • Doctor Philosophy

    Understanding the role of HER2 in cardiac function.

    Associate Advisor

    Other advisors: Associate Professor Fiona Simpson, Dr Melissa Reichelt

  • Doctor Philosophy

    Deciphering the Role of Immune Signalling in Cardiac Dysfunction

    Associate Advisor

  • Doctor Philosophy

    Understanding the role of WD40-Repeat Protein 62 (WDR62) in the regulation of heart function.

    Associate Advisor

    Other advisors: Associate Professor Dominic Ng, Dr Melissa Reichelt

  • Doctor Philosophy

    The role of C5a and ß-1 adrenergic receptors on cardiovascular function in cats

    Associate Advisor

    Other advisors: Professor Trent Woodruff, Professor Paul Mills

  • Doctor Philosophy

    Understanding how an old heart gets stiff

    Associate Advisor

    Other advisors: Dr Melissa Reichelt

Completed supervision

Enquiries

Contact Professor Wally Thomas directly for media enquiries about:

  • Cardiovascular disease
  • Cardiovascular system
  • Cell biology
  • Cell signalling
  • G protein-coupled receptors
  • Heart disease

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