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2024 Conference Publication Targeting Cardiomyocytes with Adeno Associated Viruses to Protect Hearts from Trastuzumab-induced CardiotoxicityReichelt, Melissa, Ho, Uda, Bunt, Kelsey, Watson, Sophie, Patel, Kinjal, Bradford, Julia and Thomas, Walter G. (2024). Targeting Cardiomyocytes with Adeno Associated Viruses to Protect Hearts from Trastuzumab-induced Cardiotoxicity. American Physiology Summit 2024, Long Beach, CA United States, 4-7 April 2024. Rockville, MD United States: American Physiological Society. doi: 10.1152/physiol.2024.39.s1.2480 |
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2024 Journal Article Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarctionRedd, Meredith A, Yoshikawa, Yusuke, Khan, Nemat, Waqar, Maleeha, Saez, Natalie J, Outhwaite, Jennifer E, Russell, Jake S, Hanna, Amy D, Chiu, Han S, Er, Sing Yan, Butcher, Neville J, Mardon, Karine, Fraser, John F, Smythe, Mark L, Rash, Lachlan D, Thomas, Walter G, King, Glenn F, Reichelt, Melissa E and Palpant, Nathan J (2024). Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction. European Heart Journal, 45 (17), 1571-1574. doi: 10.1093/eurheartj/ehad793 |
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2024 Journal Article Cardiac human bitter taste receptors contain naturally occurring variants that alter functionBloxham, Conor J., Hulme, Katina D., Fierro, Fabrizio, Fercher, Christian, Pegg, Cassandra L., O'Brien, Shannon L., Foster, Simon R., Short, Kirsty R., Furness, Sebastian G. B., Reichelt, Melissa E., Niv, Masha Y. and Thomas, Walter G. (2024). Cardiac human bitter taste receptors contain naturally occurring variants that alter function. Biochemical Pharmacology, 219 115932, 115932. doi: 10.1016/j.bcp.2023.115932 |
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2023 Journal Article Angiotensin receptors in GtoPdb v.2023.1Alexander, Wayne, Bernstein, Kenneth E., Catt, Kevin J., De Gasparo, Marc, Dhanachandra Singh, Khuraijam, Eguchi, Satoru, Escher, Emanuel, Goodfriend, Theodore L., Horiuchi, Mastgugu, Hunyady, László, Husain, Ahsan, Inagami, Tadashi, Karnik, Sadashiva, Kemp, Jacqueline, Thomas, Walter G., Timmermans, Pieter B. M. W. M., Tirupula, Kalyan, Unal, Hamiyet, Unger, Thomas and Vanderheyden, Patrick (2023). Angiotensin receptors in GtoPdb v.2023.1. IUPHAR/BPS Guide to Pharmacology CITE, 2023 (1), 1-21. doi: 10.2218/gtopdb/f6/2023.1 |
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2023 Conference Publication A bitter taste in your heart: cardiac cells expressing T2Rs and polymorhpisms that affect cardiac functionThomas, Walter G., Bloxham, Conor J., Dashwood, Alexander, Cheesman, Elizabeth, Hulme, Katina D., Khoo, Hui Y., Russell, Jake D., Yoshikawa, Yusuke, Reichelt, Melissa E., Short, Kirsty R., Furness, Sebastian B. G., Foster, Simon R. and Molenaar, Peter (2023). A bitter taste in your heart: cardiac cells expressing T2Rs and polymorhpisms that affect cardiac function. 45th Annual Meeting of the Association-for-Chemoreception-Sciences, Bonita Springs, FL, United States, 19-22 April 2023. Oxford, United Kingdom: Oxford University Press. |
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2023 Journal Article Early cardiac aging linked to impaired stress-resistance and transcriptional control of stress response, quality control and mitochondrial pathwaysAshton, Kevin J., Kiessling, Can J., Thompson, Jamie-Lee M., Aziz, Aliah Y., Thomas, Walter G., Headrick, John P. and Reichelt, Melissa E. (2023). Early cardiac aging linked to impaired stress-resistance and transcriptional control of stress response, quality control and mitochondrial pathways. Experimental Gerontology, 171 112011, 1-15. doi: 10.1016/j.exger.2022.112011 |
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2022 Journal Article Akt acts as a switch for GPCR transactivation of the TGF‐β receptor type 1Mohamed, Raafat, Shajimoon, Aravindra, Afroz, Rizwana, Gabr, Mai, Thomas, Wally, Little, Peter J. and Kamato, Danielle (2022). Akt acts as a switch for GPCR transactivation of the TGF‐β receptor type 1. The FEBS Journal, 289 (9), 2642-2656. doi: 10.1111/febs.16297 |
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2022 Journal Article A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammalsEagles, David A., Saez, Natalie J., Krishnarjuna, Bankala, Bradford, Julia J., Chin, Yanni K.-Y., Starobova, Hana, Mueller, Alexander, Reichelt, Melissa E., Undheim, Eivind A. B., Norton, Raymond S., Thomas, Walter G., Vetter, Irina, King, Glenn F. and Robinson, Samuel D. (2022). A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals. Proceedings of the National Academy of Sciences, 119 (7) e2112630119. doi: 10.1073/pnas.2112630119 |
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2021 Journal Article Corrigendum to “BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes” [Biochem. Pharmacol. 158 (2108) 232–242] (Biochemical Pharmacology (2018) 158 (232–242), (S0006295218304386), (10.1016/j.bcp.2018.10.017))O'Brien, Shannon L., Johnstone, Elizabeth K.M., Devost, Dominic, Conroy, Jacinta, Reichelt, Melissa E., Purdue, Brooke W., Ayoub, Mohammed A., Kawai, Tatsuo, Inoue, Asuka, Eguchi, Satoru, Hébert, Terence E., Pfleger, Kevin D.G. and Thomas, Walter G. (2021). Corrigendum to “BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes” [Biochem. Pharmacol. 158 (2108) 232–242] (Biochemical Pharmacology (2018) 158 (232–242), (S0006295218304386), (10.1016/j.bcp.2018.10.017)). Biochemical Pharmacology, 192 114756, 114756. doi: 10.1016/j.bcp.2021.114756 |
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2021 Journal Article Therapeutic inhibition of acid sensing ion channel 1a recovers heart function after ischemia-reperfusion injuryRedd, Meredith A., Scheuer, Sarah E., Saez, Natalie J., Yoshikawa, Yusuke, Chiu, Han Sheng, Gao, Ling, Hicks, Mark, Villanueva, Jeanette E., Joshi, Yashutosh, Chow, Chun Yuen, Cuellar-Partida, Gabriel, Peart, Jason N., See Hoe, Louise E., Chen, Xiaoli, Sun, Yuliangzi, Suen, Jacky Y., Hatch, Robert J., Rollo, Ben, Xiao, Di, Alzubaidi, Mubarak A.H., Maljevic, Snezana, Quaife-Ryan, Gregory A., Hudson, James E., Porrello, Enzo R., White, Melanie Y., Cordwell, Stuart J., Fraser, John F., Petrou, Steven, Reichelt, Melissa E. ... Palpant, Nathan J. (2021). Therapeutic inhibition of acid sensing ion channel 1a recovers heart function after ischemia-reperfusion injury. Circulation, 144 (12), 947-960. doi: 10.1161/circulationaha.121.054360 |
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2021 Journal Article The concise guide to pharmacology 2021/22: G protein‐coupled receptorsAlexander, Stephen PH, Christopoulos, Arthur, Davenport, Anthony P, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Abbracchio, Maria Pia, Alexander, Wayne, Al‐hosaini, Khaled, Bäck, Magnus, Barnes, Nicholas M., Bathgate, Ross, Beaulieu, Jean‐Martin, Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel J.M., Blaho, Victoria, Boulay, Francois, Bousquet, Corinne, Bräuner‐Osborne, Hans, Burnstock, Geoffrey, Caló, Girolamo ... Ye, Richard D. (2021). The concise guide to pharmacology 2021/22: G protein‐coupled receptors. British Journal of Pharmacology, 178 (S1), S27-S156. doi: 10.1111/bph.15538 |
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2021 Journal Article Type I diabetes mellitus increases the cardiovascular complications of influenza virus infectionSinclair, Jane E., Bloxham, Conor J., Chiu, Han, Chew, Keng Yih, Russell, Jake, Yoshikawa, Yusuke, Bielefeldt-Ohmann, Helle, Steele, Lauren E., Hulme, Katina D., Verzele, Nathalie A. J., Noye, Ellesandra C., Wu, Melanie, Reichelt, Melissa E., Thomas, Walter G., Gallo, Linda A., Redd, Meredith A. and Short, Kirsty R. (2021). Type I diabetes mellitus increases the cardiovascular complications of influenza virus infection. Frontiers in Cellular and Infection Microbiology, 11 714440, 714440. doi: 10.3389/fcimb.2021.714440 |
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2021 Journal Article Stimulation of the four isoforms of receptor tyrosine kinase ErbB4, but not ErbB1, confers cardiomyocyte hypertrophyWang, Zhen, Chan, Hsiu‐Wen, Gambarotta, Giovanna, Smith, Nicola J., Purdue, Brooke W., Pennisi, David J., Porrello, Enzo R., O'Brien, Shannon L., Reichelt, Melissa E., Thomas, Walter G. and Paravicini, Tamara M. (2021). Stimulation of the four isoforms of receptor tyrosine kinase ErbB4, but not ErbB1, confers cardiomyocyte hypertrophy. Journal of Cellular Physiology, 236 (12) jcp.30487, 8160-8170. doi: 10.1002/jcp.30487 |
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2021 Journal Article Complex interactions between the angiotensin II type 1 receptor, the epidermal growth factor receptor and TRIO-dependent signaling partnersJohnstone, Elizabeth K.M., Abhayawardana, Rekhati S., See, Heng B., Seeber, Ruth M., O'Brien, Shannon L., Thomas, Walter G. and Pfleger, Kevin D.G. (2021). Complex interactions between the angiotensin II type 1 receptor, the epidermal growth factor receptor and TRIO-dependent signaling partners. Biochemical Pharmacology, 188 114521, 1-16. doi: 10.1016/j.bcp.2021.114521 |
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2020 Journal Article Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodiesGormal, Rachel S., Padmanabhan, Pranesh, Kasula, Ravikiran, Bademosi, Adekunle T., Coakley, Sean, Giacomotto, Jean, Blum, Ailisa, Joensuu, Merja, Wallis, Tristan P., Lo, Harriet P., Budnar, Srikanth, Rae, James, Ferguson, Charles, Bastiani, Michele, Thomas, Walter G., Pardon, Els, Steyaert, Jan, Yap, Alpha S., Goodhill, Geoffrey J., Hilliard, Massimo A., Parton, Robert G. and Meunier, Frédéric A. (2020). Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies. Proceedings of the National Academy of Sciences of the United States of America, 117 (48), 30476-30487. doi: 10.1073/pnas.2007443117 |
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2020 Journal Article A high fat diet increases influenza A virus-associated cardiovascular damageSiegers, Jurre Y., Novakovic, Boris, Hulme, Katina D., Marshall, Rebecca, Bloxham, Conor J., Thomas, Walter G., Reichelt, Mellissa E., Leijten, Lonneke, van Run, Peter, Knox, Karen, Sokolowski, Kamil A., Tse, Brian W. C., Chew, Keng Yih, Christ, Angelika N., Howe, Greg, Bruxner, Timothy J. C., Karolyi, Mario, Pawelka, Erich, Koch, Rebecca M., Bellmann-Weiler, Rosa, Burkert, Francesco, Weiss, Günter, Samanta, Romit J., Openshaw, Peter J. M., Bielefeldt-Ohmann, Helle, van Riel, Debby and Short, Kirsty R. (2020). A high fat diet increases influenza A virus-associated cardiovascular damage. The Journal of infectious diseases, 222 (5), 820-831. doi: 10.1093/infdis/jiaa159 |
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2020 Journal Article A bitter taste in your heartBloxham, Conor J., Foster, Simon R. and Thomas, Walter G. (2020). A bitter taste in your heart. Frontiers in Physiology, 11 431, 431. doi: 10.3389/fphys.2020.00431 |
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2020 Conference Publication Naturally occurring, non-functional polymorphisms in cardiac T2R (bitter taste) receptorsBloxham, Conor, Foster, Simon and Thomas, Walter (2020). Naturally occurring, non-functional polymorphisms in cardiac T2R (bitter taste) receptors. 29th Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Trieste, Italy, 11-14 September 2019. Oxford, United Kingdom: Oxford University Press. |
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2019 Journal Article The Concise Guide to Pharmacology 2019/20: G protein‐coupled receptorsAlexander, Stephen P. H., Christopoulos, Arthur, Davenport, Anthony P., Kelly, Eamonn, Mathie, Alistair, Peters, John A., Veale, Emma L., Armstrong, Jane F., Faccenda, Elena, Harding, Simon D., Pawson, Adam J., Sharman, Joanna L., Southan, Christopher, Davies, Jamie A., Abbracchio, Maria P., Alexander, Wayne, Al-hosaini, Khaled, Bäck, Magnus, Beaulieu, Jean‐Martin, Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel J.M., Blaho, Victoria, Bousquet, Corinne, Bräuner-Osborne, Hans, Burnstock, Geoffrey, Caló, Girolamo, Castaño, Justo P., Catt, Kevin J. ... Yao, Chengcan (2019). The Concise Guide to Pharmacology 2019/20: G protein‐coupled receptors. British Journal of Pharmacology, 176 (S1), S21-S141. doi: 10.1111/bph.14748 |
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2019 Conference Publication Cardiomyocyte ErbB4 receptors are essential for developmental cardiac hypertrophy and cardiac function in adult heartsReichelt, M., Wang, Z., Thorn, C., Paravicini, T. and Thomas, W. G. (2019). Cardiomyocyte ErbB4 receptors are essential for developmental cardiac hypertrophy and cardiac function in adult hearts. ESC Congress / World Congress of Cardiology, Paris, France, 31 August - 4 September 2019. Oxford, United Kingdom: Oxford University Press. |
