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2019 Conference Publication Cardiomyocyte ErbB4 receptors are essential for developmental cardiac hypertrophy and cardiac function in adult heartsReichelt, M., Wang, Z., Thorn, C., Paravicini, T. and Thomas, W. G. (2019). Cardiomyocyte ErbB4 receptors are essential for developmental cardiac hypertrophy and cardiac function in adult hearts. ESC Congress / World Congress of Cardiology, Paris, France, 31 August - 4 September 2019. Oxford, United Kingdom: Oxford University Press. |
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2019 Journal Article Mutations in the NPxxY motif stabilize pharmacologically distinct conformational states of the α1B- and β2-adrenoceptorsRagnarsson, Lotten, Andersson, Åsa, Thomas, Walter G. and Lewis, Richard J. (2019). Mutations in the NPxxY motif stabilize pharmacologically distinct conformational states of the α1B- and β2-adrenoceptors. Science Signaling, 12 (572) eaas9485, eaas9485. doi: 10.1126/scisignal.aas9485 |
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2018 Journal Article BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexesO'Brien, Shannon L., Johnstone, Elizabeth K. M., Devost, Dominic, Conroy, Jacinta, Reichelt, Melissa E., Purdue, Brooke W., Ayoub, Mohammed A., Kawai, Tatsuo, Inoue, Asuka, Eguchi, Satoru, Hébert, Terence E., Pfleger, Kevin D.G. and Thomas, Walter G. (2018). BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes. Biochemical Pharmacology, 158, 232-242. doi: 10.1016/j.bcp.2018.10.017 |
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2017 Journal Article Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrestMills, Richard J., Titmarsh, Drew M., Koenig, Xaver, Parker, Benjamin L., Ryall, James G., Quaife-Ryan, Gregory A., Voges, Holly K., Hodson, Mark P., Ferguson, Charles, Drowley, Lauren, Plowright, Alleyn T., Needham, Elise J., Wang, Qing-Dong, Gregorevic, Paul, Xin, Mei, Thomas, Walter G., Parton, Robert G., Nielsen, Lars K., Launikonis, Bradley S., James, David E., Elliott, David A., Porrello, Enzo R. and Hudson, James E. (2017). Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest. Proceedings of the National Academy of Sciences of the United States of America, 114 (40), E8372-E8381. doi: 10.1073/pnas.1707316114 |
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2017 Journal Article Cavin-1 deficiency modifies myocardial and coronary function, stretch responses and ischaemic tolerance: roles of NOS over-activityKaakinen, Mika, Reichelt, Melissa E., Ma, Zhibin, Ferguson, Charles, Martel, Nick, Porrello, Enzo R., Hudson, James E., Thomas, Walter G., Parton, Robert G. and Headrick, John P. (2017). Cavin-1 deficiency modifies myocardial and coronary function, stretch responses and ischaemic tolerance: roles of NOS over-activity. Basic Research in Cardiology, 112 (3) 24, 24. doi: 10.1007/s00395-017-0613-6 |
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2017 Journal Article Gaq proteins: molecular pharmacology and therapeutic potentialKamato, Danielle, Mitra, Partha, Davis, Felicity, Osman, Narin, Chaplin, Rebecca, Cabot, Peter J., Afroz, Rizwana, Thomas, Walter, Zheng, Wenhua, Kaur, Harveen, Brimble, Margaret and Little, Peter J. (2017). Gaq proteins: molecular pharmacology and therapeutic potential. Cellular and Molecular Life Sciences, 74 (8), 1379-1390. doi: 10.1007/s00018-016-2405-9 |
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2017 Journal Article CRIM1 is necessary for coronary vascular endothelial cell development and homeostasisIyer, Swati, Chhabra, Yash, Harvey, Tracey J., Wang, Richard, Chiu, Han Sheng, Smith, A. G., Thomas, Walter G., Pennisi, David J. and Piper, Michael (2017). CRIM1 is necessary for coronary vascular endothelial cell development and homeostasis. Journal of Molecular Histology, 48 (1), 53-61. doi: 10.1007/s10735-016-9702-3 |
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2017 Journal Article Transactivation of the epidermal growth factor receptor in responses to myocardial stress and cardioprotectionReichelt, Melissa E., O'Brien, Shannon, Thomas, Walter G. and Headrick, John P. (2017). Transactivation of the epidermal growth factor receptor in responses to myocardial stress and cardioprotection. International Journal of Biochemistry and Cell Biology, 83, 97-110. doi: 10.1016/j.biocel.2016.12.014 |
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2017 Conference Publication Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrestHudson, J., Mills, R., Titmarsh, D., Koenig, X., Parker, B., Ryall, J., Quaife-Ryan, G., Voges, H., Hodson, M., Ferguson, C., Drowley, L., Plowright, A., Wang, Q., Gregorevic, P., Xin, M., Thomas, W., Parton, R., Nielsen, L., Launikonis, B., James, D., Elliott, D. and Porrello, E. (2017). Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest. Abstracts for the 65th Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Perth, Australia, 10 - 13 August 2017. Chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2017.06.375 |
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2016 Conference Publication Cellular transcriptomic analysis of multiple cardiac lineages during heart development and regenerationRyan, Quaife-G., Ma, Z., Sim, C., Ramialison, M., Thomas, W., Hudson, J. and Porrello, E. (2016). Cellular transcriptomic analysis of multiple cardiac lineages during heart development and regeneration. 64th Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Adelaide, SA Australia, 4 – 7 August 2016. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2016.06.079 |
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2016 Conference Publication TAS2Rs-A new class of functional G protein-coupled receptors in heart.Thomas, Walter (2016). TAS2Rs-A new class of functional G protein-coupled receptors in heart.. 25th Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Istanbul Turkey, Sep 01-05, 2015. OXFORD: OXFORD UNIV PRESS. |
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2016 Journal Article Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signallingLittle, P. J., Hollenberg, M. D, Kamato, D., Thomas, W., Chen, J., Wang, T., Zheng, W. and Osman, N. (2016). Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signalling. British Journal of Pharmacology, 173 (20), 2992-3000. doi: 10.1111/bph.13398 |
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2016 Journal Article Crim1 has cell-autonomous and paracrine roles during embryonic heart developmentIyer, Swati, Chou, Fang Yu, Wang, Richard, Chiu, Han Sheng, Raju, Vinay K. Sundar, Little, Melissa H., Thomas, Walter G., Piper, Michael and Pennisi, David J. (2016). Crim1 has cell-autonomous and paracrine roles during embryonic heart development. Scientific Reports, 6 (1) 19832, 19832 .1-19832 .15. doi: 10.1038/srep19832 |
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2016 Journal Article Epidermal growth factor receptor transactivation: mechanisms, pathophysiology, and potential therapies in the cardiovascular systemForrester, Steven J., Kawai, Tatsuo, O'Brien, Shannon, Thomas, Walter, Harris, Raymond C. and Eguchi, Satoru (2016). Epidermal growth factor receptor transactivation: mechanisms, pathophysiology, and potential therapies in the cardiovascular system. Annual Review of Pharmacology and Toxicology, 56 (1), 627-653. doi: 10.1146/annurev-pharmtox-070115-095427 |
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2016 Journal Article Taste and hypertension in humans: targeting cardiovascular diseaseRoura, Eugeni, Foster, Simon, Winklebach, Anja, Navarro, Marta, Thomas, Walter, Campbell, Katrina and Stowasser, Michael (2016). Taste and hypertension in humans: targeting cardiovascular disease. Current Pharmaceutical Design, 22 (15), 2290-2305. doi: 10.2174/1381612822666160216151545 |
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2015 Journal Article Angiotensin receptors: Interpreters of pathophysiological angiotensinergic stimulisKarnik, Sadashiva S., Unal, Hamiyet, Kemp, Jacqueline R., Tirupula, Kalyan C., Eguchi, Satoru, Vanderheyden, Patrick M. L. and Thomas, Walter G. (2015). Angiotensin receptors: Interpreters of pathophysiological angiotensinergic stimulis. Pharmacological Reviews, 67 (4), 754-819. doi: 10.1124/pr.114.010454 |
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2015 Journal Article Variability in human bitter taste sensitivity to chemically diverse compounds can be accounted for by differential TAS2R activationRoura, Eugeni, Aldayyani, Asya, Thavaraj, Pridhuvi, Prakash, Sangeeta, Greenway, Delma, Thomas, Walter G., Meyerhof, Wolfgang, Roudnitzky, Natacha and Foster, Simon R. (2015). Variability in human bitter taste sensitivity to chemically diverse compounds can be accounted for by differential TAS2R activation. Chemical Senses, 40 (6), 427-435. doi: 10.1093/chemse/bjv024 |
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2015 Journal Article Helix 8 of the angiotensin- II type 1A receptor interacts with phosphatidylinositol phosphates and modulates membrane insertionHirst, Daniel J., Lee, Tzong-Hsien, Pattenden, Leonard K., Thomas, Walter G. and Aguilar, Marie-Isabel (2015). Helix 8 of the angiotensin- II type 1A receptor interacts with phosphatidylinositol phosphates and modulates membrane insertion. Scientific Reports, 5 (1) 9972, 1-14. doi: 10.1038/srep09972 |
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2015 Journal Article Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulationFoster, Simon R., Porrello, Enzo R., Stefani, Maurizio, Smith, Nicola J., Molenaar, Peter, Dos Remedios, Cristobal G., Thomas, Walter G. and Ramialison, Mirana (2015). Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation. Naunyn-Schmiedeberg's Archives of Pharmacology, 388 (10) 1118, 1009-1027. doi: 10.1007/s00210-015-1118-1 |
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2015 Journal Article Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors 1 and 2Clayton, Daniel, Hanchapola, Iresha, Thomas, Walter G., Widdop, Robert E., Smith, Alexander I., Perlmutter, Patrick and Aguilar, Marie-Isabel (2015). Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors 1 and 2. Frontiers in Pharmacology, 6 (JAN) 05, 5.1-5.9. doi: 10.3389/fphar.2015.00005 |
