Professor

Wally Thomas

Email: 
Phone: 
+61 7 336 51074

Availability

Professor Wally Thomas is:
Available for supervision
Media expert

Fields of research

Biological Sciences Cardiovascular medicine and haematology Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Science, The University of Queensland
  • Bachelor (Honours) of Science (Advanced), The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Search Professor Wally Thomas’s works on UQ eSpace

174 works between 1985 and 2024
All (174) Journal Article (139) Book Chapter (4) Conference Publication (31)

61 - 80 of 174 works

2011

Journal Article

Heteromerization of angiotensin receptors changes trafficking and arrestin recruitment profiles

Porrello, Enzo R., Pfleger, Kevin D. G., Seeber, Ruth M., Qian, Hongwei, Oro, Cristina, Abogadie, Fe, Delbridge, Lea M. D. and Thomas, Walter G. (2011). Heteromerization of angiotensin receptors changes trafficking and arrestin recruitment profiles. Cellular Signalling, 23 (11), 1767-1776. doi: 10.1016/j.cellsig.2011.06.011

Heteromerization of angiotensin receptors changes trafficking and arrestin recruitment profiles

2011

Journal Article

Relative affinity of angiotensin peptides and novel ligands at AT(1) and AT(2) receptors

Bosnyak, Sanja, Jones, Emma S., Christopoulos, Arthur, Aguilar, Marie-Isabel, Thomas, Walter G. and Widdop, Robert E. (2011). Relative affinity of angiotensin peptides and novel ligands at AT(1) and AT(2) receptors. Clinical Science, 121 (7), 297-303. doi: 10.1042/CS20110036

Relative affinity of angiotensin peptides and novel ligands at AT(1) and AT(2) receptors

2011

Journal Article

Regulation of angiotensinogen by angiotensin II in mouse primary astrocyte cultures

O'Callaghan, E.L., Bassi, J.K., Porrello, E.R., Delbridge, L.M.D., Thomas, W.G. and Allen, A.M. (2011). Regulation of angiotensinogen by angiotensin II in mouse primary astrocyte cultures. Journal of Neurochemistry, 119 (1), 18-26. doi: 10.1111/j.1471-4159.2011.07406.x

Regulation of angiotensinogen by angiotensin II in mouse primary astrocyte cultures

2011

Conference Publication

Knockdown of Angiotensinogen Protein in Vivo

O'Callaghan, E. L., Thomas, W. G. and Allen, A. M. (2011). Knockdown of Angiotensinogen Protein in Vivo. 32nd Annual Scientific Meeting of the High Blood Pressure Research Council of Australia, Melbourne Australia, Dec 01-03, 2010. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Knockdown of Angiotensinogen Protein in Vivo

2011

Conference Publication

SINGLE BETA-AMINO ACID SUBSTITUTIONS TO ANGIOTENSIN II CONFER AT2 RECEPTOR SELECTIVITY AND VASCULAR FUNCTION

Bosnyak, S., Jones, E. S., Kirsch, J. F., Del Borgo, M. P., Welungoda, I., Clayton, D., Hausler, N., Unabia, S., Perlmutter, P., Thomas, W. G., Aguilar, M-I and Widdop, R. E. (2011). SINGLE BETA-AMINO ACID SUBSTITUTIONS TO ANGIOTENSIN II CONFER AT2 RECEPTOR SELECTIVITY AND VASCULAR FUNCTION. 32nd Annual Scientific Meeting of the High Blood Pressure Research Council of Australia, Melbourne Australia, Dec 01-03, 2010. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

SINGLE BETA-AMINO ACID SUBSTITUTIONS TO ANGIOTENSIN II CONFER AT2 RECEPTOR SELECTIVITY AND VASCULAR FUNCTION

2011

Journal Article

Determination of the exact molecular requirements for type 1 angiotensin receptor epidermal growth factor receptor transactivation and cardiomyocyte hypertrophy

Smith, Nicola J., Chan, Hsiu-Wen, Qian, Hongwei, Bourne, Allison M., Hannan, Katherine M, Warner, Fiona J., Ritchie, Rebecca H., Pearson, Richard B., Hannan, Ross D. and Thomas, Walter G. (2011). Determination of the exact molecular requirements for type 1 angiotensin receptor epidermal growth factor receptor transactivation and cardiomyocyte hypertrophy. Hypertension, 57 (5), 973-980. doi: 10.1161/HYPERTENSIONAHA.110.166710

Determination of the exact molecular requirements for type 1 angiotensin receptor epidermal growth factor receptor transactivation and cardiomyocyte hypertrophy

2011

Conference Publication

Role of angiotensin in the rostral ventrolateral medulla in the pressor response to aversive stress

Chen, Daian, Thu-Phuc Nguyen-Huu, Bassi, Jaspreet K., Davern, Pamela, Thomas, Walter G., Head, Geoff A. and Allen, Andrew M. (2011). Role of angiotensin in the rostral ventrolateral medulla in the pressor response to aversive stress. Experimental Biology Meeting 2011, Washington Dc, Apr 09-13, 2011. BETHESDA: FEDERATION AMER SOC EXP BIOL.

Role of angiotensin in the rostral ventrolateral medulla in the pressor response to aversive stress

2011

Journal Article

A single beta-amino acid substitution to angiotensin II confers AT(2) receptor selectivity and vascular function

Jones, Emma S., Del Borgo, Mark P., Kirsch, Julian F., Clayton, Daniel, Bosnyak, Sanja, Welungoda, Iresha, Hausler, Nicholas, Unabia, Sharon, Perlmutter, Patrick, Thomas, Walter G., Aguilar, Marie-Isabel and Widdop, Robert E. (2011). A single beta-amino acid substitution to angiotensin II confers AT(2) receptor selectivity and vascular function. Hypertension, 57 (3 Part 2), 570-576. doi: 10.1161/HYPERTENSIONAHA.110.164301

A single beta-amino acid substitution to angiotensin II confers AT(2) receptor selectivity and vascular function

2011

Conference Publication

UMR-106 osteoblast cells express components of the renin-angiotensin system and are regulated by glucocorticoids

Lei, C., MacRae, K., Thomas, W. and Sernia, C. (2011). UMR-106 osteoblast cells express components of the renin-angiotensin system and are regulated by glucocorticoids. 2nd Asia-Pacific Osteoporosis and Bone Meeting, Gold Coast , QLD Australia, 4th-8th September 2011.

UMR-106 osteoblast cells express components of the renin-angiotensin system and are regulated by glucocorticoids

2011

Conference Publication

ANGIOTENSIN II INCREASES OSTEOBLAST RANKL:OPG RATIO THROUGH TRANSACTIVATION OF ERBB RECEPTORS BY EGF-LIKE LIGANDS

MacRae, K, Thomas, W and Sernia C (2011). ANGIOTENSIN II INCREASES OSTEOBLAST RANKL:OPG RATIO THROUGH TRANSACTIVATION OF ERBB RECEPTORS BY EGF-LIKE LIGANDS. European Congress on Osteoporosis and Osteoarthritis – ESCEO11, Valencia Spain, 23-26 March 2011.

ANGIOTENSIN II INCREASES OSTEOBLAST RANKL:OPG RATIO THROUGH TRANSACTIVATION OF ERBB RECEPTORS BY EGF-LIKE LIGANDS

2011

Conference Publication

Angiotensin II increases osteoblast RANKL:OPG ratio through transactivation of ErbB receptors by EGF-like ligands

MacRae, Kirsty, Thomas, Walter and Senia, Conrad (2011). Angiotensin II increases osteoblast RANKL:OPG ratio through transactivation of ErbB receptors by EGF-like ligands. 1st IOF-ESCEO Pre-Clinical Symposium, Valencia, SPAIN, 23-26, 2011.

Angiotensin II increases osteoblast RANKL:OPG ratio through transactivation of ErbB receptors by EGF-like ligands

2011

Conference Publication

Angiotensin II regulates RANKL:OPG ratio potentially through transactivation of ErbB receptors by EGF-like ligands

MacRae, K., Thomas, W. and Sernia C. (2011). Angiotensin II regulates RANKL:OPG ratio potentially through transactivation of ErbB receptors by EGF-like ligands. 2nd Asia-Pacific Osteoporosis and Bone Meeting, Gold Coast , QLD, Australia, 4th-8th September 2011. Springer.

Angiotensin II regulates RANKL:OPG ratio potentially through transactivation of ErbB receptors by EGF-like ligands

2010

Journal Article

The renin-angiotensin system and cancer: Old dog, new tricks

George, AJ, Thomas, WG and Hannan, RD (2010). The renin-angiotensin system and cancer: Old dog, new tricks. Nature Reviews Cancer, 10 (11), 745-759. doi: 10.1038/nrc2945

The renin-angiotensin system and cancer: Old dog, new tricks

2010

Journal Article

Ligand-supported purification of the urotensin-II receptor

Du, Ann T., Onan, Döne, Dinh, Diem T., Lew, Michael J., Ziogas, James, Aguilar, Marie-Isabel, Pattenden, Leonard K. and Thomas, Walter G. (2010). Ligand-supported purification of the urotensin-II receptor. Molecular Pharmacology, 78 (4), 639-647. doi: 10.1124/mol.110.065151

Ligand-supported purification of the urotensin-II receptor

2010

Journal Article

Expression of angiotensin type 1A receptors in C1 neurons restores the sympathoexcitation to angiotensin in the rostral ventrolateral medulla of angiotensin type 1A knockout mice

Chen, DA, Bassi, JK, Walther, T, Thomas, WG and Allen, AM (2010). Expression of angiotensin type 1A receptors in C1 neurons restores the sympathoexcitation to angiotensin in the rostral ventrolateral medulla of angiotensin type 1A knockout mice. Hypertension, 56 (1), 143-150. doi: 10.1161/HYPERTENSIONAHA.110.151704

Expression of angiotensin type 1A receptors in C1 neurons restores the sympathoexcitation to angiotensin in the rostral ventrolateral medulla of angiotensin type 1A knockout mice

2010

Conference Publication

REDUCED ANGIOTENSINOGEN GENE EXPRESSION FOLLOWING ANGIOTENSIN II STIMULATION OF ASTROCYTES EXPRESSING THE ANGIOTENSIN TYPE 1A RECEPTOR

O'Callaghan, EL, Thomas, WG and Allen, AM (2010). REDUCED ANGIOTENSINOGEN GENE EXPRESSION FOLLOWING ANGIOTENSIN II STIMULATION OF ASTROCYTES EXPRESSING THE ANGIOTENSIN TYPE 1A RECEPTOR. 31st Annual Scientific Meeting of the High-Blood-Pressure-Research-Council-of-Australia, Sydney AUSTRALIA, DEC 01-03, 2009.

REDUCED ANGIOTENSINOGEN GENE EXPRESSION FOLLOWING ANGIOTENSIN II STIMULATION OF ASTROCYTES EXPRESSING THE ANGIOTENSIN TYPE 1A RECEPTOR

2010

Conference Publication

Beta-amino acid substituted Angiotensin II peptidomimetics as AT2 receptor-selective ligands

Widdop, RE, Kirsch, J, Bosnyak, S, Unabia, S, Del Borgo, M, Perlmutter, P, Thomas, W, Aguilar, MI and Jones, ES (2010). Beta-amino acid substituted Angiotensin II peptidomimetics as AT2 receptor-selective ligands. Conference on High Blood Pressure Research, Washington, DC, U.S.A., 13-16 October 2010. Philadelphia, PA, U.S.A.: Lippincott Williams & Wilkins. doi: 10.1161/HYP.0b013e3181faa059

Beta-amino acid substituted Angiotensin II peptidomimetics as AT2 receptor-selective ligands

2009

Journal Article

Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival

Lattin, J. E., Greenwood, K. P., Daly, N. L., Kelly, G, Zidar, D. A., Clark, R. J., Thomas, W. G., Kellie, Stuart, Craik, D. J., Hume, D. A. and Sweet, M. J. (2009). Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival. Molecular Immunology, 47 (2-3), 340-347. doi: 10.1016/j.molimm.2009.09.012

Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival

2009

Journal Article

Glucocorticoids Suppress Growth in Neonatal Cardiomyocytes Co-Expressing AT(2) and AT(1) Angiotensin Receptors

Porrello, Enzo R, Meeker, William F, Thomas, Walter G, Widdop, Robert E and Delbridge, Lea MD (2009). Glucocorticoids Suppress Growth in Neonatal Cardiomyocytes Co-Expressing AT(2) and AT(1) Angiotensin Receptors. Neonatology, 97 (3), 257-265. doi: 10.1159/000253757

Glucocorticoids Suppress Growth in Neonatal Cardiomyocytes Co-Expressing AT(2) and AT(1) Angiotensin Receptors

2009

Journal Article

Endothelin-1 activates ETA receptors on human vascular smooth muscle cells to yield proteoglycans with increased binding to LDL

Ballinger, M. L., Ivey, M. E., Osman, N., Thomas, W. G. and Little, P. J. (2009). Endothelin-1 activates ETA receptors on human vascular smooth muscle cells to yield proteoglycans with increased binding to LDL. Atherosclerosis, 205 (2), 451-457. doi: 10.1016/j.atherosclerosis.2009.01.024

Endothelin-1 activates ETA receptors on human vascular smooth muscle cells to yield proteoglycans with increased binding to LDL

Current funding

  • 2023 - 2025
    Studying the basis of and developing new therapies to treat heart disease
    IPF Healthy - Medical Research
    Open grant
  • 2023 - 2025
    Protecting hearts from trastuzumab-induced cardiomyopathy
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2022 - 2024
    Targeting cavin-1 via gene therapy in a model of metabolic/low-level chronic stress
    Diabetes Australia Research Program
    Open grant
  • 2020 - 2023
    Understanding how an old heart gets stiff
    ARC Discovery Projects
    Open grant
  • 2019 - 2022
    How tissues generate the peptide hormone angiotensin II
    ARC Discovery Projects
    Open grant
  • 2019
    Vevo 3100 Imaging System for ultrahigh resolution and frame rate echocardiographic assessment of small animals.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017 - 2018
    A potential role for C5a antagonism in the medical management of feline hypertrophic cardiornyopathy
    Peter & Mary Ellen Stone Memorial Fund
    Open grant
  • 2017 - 2018
    A Pharmacology Screening Facility to Accelerate Drug Discovery and Development
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015
    A state-of-the-art spinning disc confocal microscope for high speed imaging of live cells and super resolution microscopy
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2017
    New mediators of GPCR-growth factor receptor transactivation
    NHMRC Project Grant
    Open grant
  • 2015 - 2017
    PIPS regulate the type 1 angiotensin receptor (NHMRC Project Grant administered by Monash University)
    Monash University
    Open grant
  • 2014 - 2016
    Dietary Na reduction, food hedonism and hypertension
    UQ Collaboration and Industry Engagement Fund - Seed Research Grant
    Open grant
  • 2014
    Establishment of a small animal surgical suite for integrative physiology.
    Open grant
  • 2014
    Mitochondrial analysis suite
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013 - 2015
    Chemosensory receptors in heart
    National Heart Foundation of Australia
    Open grant
  • 2013
    Establishment of an Integrated Facility for Single Cell Analysis
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012
    Establishment of Integrated Small Animal Metabolic and Physiology Assessment Facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012
    Examining vascular structure and function using pressurised myography
    NHMRC Equipment Grant
    Open grant
  • 2012 - 2016
    Manipulating store-operated Ca2+ entry to improve muscle function in dystrophy
    NHMRC Project Grant
    Open grant
  • 2012 - 2014
    Mechanism of Epidermal Growth Factor Receptor Transactivation
    NHMRC Project Grant
    Open grant
  • 2011
    A Multi-Channel Fluorescence Plate Reader for Studying Receptor-Ligand Interactions
    NHMRC Equipment Grant
    Open grant
  • 2011 - 2013
    Role of extracellular surface residues in agonist activation of the alpha1 adrenoceptor
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    Improving muscle function in dystrophy
    UQ Collaboration and Industry Engagement Fund
    Open grant
  • 2010
    Dual channel electrophysiological recordings
    NHMRC Equipment Grant
    Open grant
  • 2010
    High content imaging analysis for bioactive and novel therapeutic target evaluation
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2012
    Molecular regulation of angiotensin receptors
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    Unravelling the sub-nuclear complexity of the brain (ARC Discovery Project administered by the University of Melbourne)
    University of Melbourne
    Open grant
  • 2009
    "Real Time PCR Facility for Biomedical Researchers"
    UQ School/Centre Co-Funding
    Open grant
  • 2009
    Establishment of a rodent cardiovascular and metabolic phenotyping platform
    UQ School/Centre Co-Funding
    Open grant
  • 2009
    Liquid Scintillation Spectroscopy Facility
    UQ School/Centre Co-Funding
    Open grant
  • 2008 - 2010
    NHMRC Senior Research Fellowship B
    NHMRC Research Fellowship
    Open grant
  • 2008 - 2010
    EGFR transactivation in cardiac hypertrophy
    NHMRC Project Grant
    Open grant
  • 2008 - 2009
    Molecular regulation of the type 1 angiotensin receptor
    NHMRC Project Grant
    Open grant
  • 2008 - 2010
    Regulation of Cardiac Hypertrophy (NHMRC grant administered by the University of Melbourne)
    Peter MacCallum Cancer Centre
    Open grant
  • 2008
    Understanding cell physiology by confocal laser scanning microscopy
    UQ Major Equipment and Infrastructure
    Open grant

Availability

Professor Wally Thomas is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    The role of neuregulin in cardiac function and failure

    Principal Advisor

    Other advisors: Dr Melissa Reichelt

  • Doctor Philosophy

    Epidermal growth factor receptors in cardiac function and disease

    Principal Advisor

    Other advisors: Dr Melissa Reichelt

  • Doctor Philosophy

    Understanding the role of HER2 in cardiac function.

    Associate Advisor

    Other advisors: Professor Fiona Simpson, Dr Melissa Reichelt

  • Doctor Philosophy

    Deciphering the Role of Immune Signalling in Cardiac Dysfunction

    Associate Advisor

  • Doctor Philosophy

    Understanding the role of WD40-Repeat Protein 62 (WDR62) in the regulation of heart function.

    Associate Advisor

    Other advisors: Associate Professor Dominic Ng, Dr Melissa Reichelt

  • Doctor Philosophy

    Understanding cardiomyocyte-endothelial cell interactions in regulating cardiac function

    Associate Advisor

    Other advisors: Dr Melissa Reichelt

  • Doctor Philosophy

    The role of C5a and ß-1 adrenergic receptors on cardiovascular function in cats

    Associate Advisor

    Other advisors: Professor Trent Woodruff, Professor Paul Mills

  • Doctor Philosophy

    Understanding cardiomyocyte-endothelial cell interactions in regulating cardiac function

    Associate Advisor

    Other advisors: Dr Melissa Reichelt

  • Doctor Philosophy

    Understanding the role of WD40-Repeat Protein 62 (WDR62) in the regulation of heart function.

    Associate Advisor

    Other advisors: Associate Professor Dominic Ng, Dr Melissa Reichelt

Completed supervision

Enquiries

Contact Professor Wally Thomas directly for media enquiries about:

  • Cardiovascular disease
  • Cardiovascular system
  • Cell biology
  • Cell signalling
  • G protein-coupled receptors
  • Heart disease

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