
Overview
Background
I graduated from The University of Tasmania, and received my PhD in Developmental Biology from The University of Queensland in 2003. My PhD, performed at the Institute for Molecular Bioscience with Prof. Melissa Little, centred on understanding the cellular and molecular mechanisms underlying embryonic kidney development. My first postdoc was performed with Prof. Christine Holt at The University of Cambridge, UK, where I studied the mechanisms by which axonal growth cones navigate to their targets in the brain, using the frog Xenopus laevis as a model system. In my second postdoctoral position, with Prof. Linda Richards at the Queensland Brain Institute at The University of Queensland, my work focussed on understanding the molecular mechanisms of neural progenitor cell specification in the developing cerebral cortex. In late 2010, I took up a joint position with the Queensland Brain Institute and The School of Biomedical Sciences (SBMS) to continue my research into the mechanisms underlying neural stem cell differentiation. I have held numerous fellowships during my career, including an NHMRC Howard Florey Fellowship, an NHMRC CDF and an ARC Future Fellowship. I currently hold a continuing Teaching and Research position within SBMS, and am currently the Director for Higher Degree Research Training at SBMS.
Availability
- Professor Michael Piper is:
- Available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), University of Tasmania
- Doctor of Philosophy, The University of Queensland
Research interests
-
Understanding the drivers of neural stem cell differentiation
What are the mechanisms that control neural stem cell (NSC) differentiation during embryogenesis, and that enable the generation of the diverse suite of neurons and glia that comprise the brain? This is a key question in developmental neuroscience. My contribution to this field to date has been to reveal central transcriptional regulators that mediate NSC biology within the brain. Using rodent model systems, I demonstrated that transcription factors of the Nuclear Factor One (NFI) family mediate NSC proliferation and differentiation in the embryonic, postnatal and adult nervous system. This work has received international recognition, as evidenced by numerous invited international presentations and high-impact reviews (e.g. Trends in Cell Biology), and forms the framework around which the hypotheses of this program will be addressed. I am interested in defining how NSC proliferation and differentiation is regulated at a transcriptional and epigenomic level within the developing nervous system. Using the developing mouse brain as a model system, we are using a suite of molecular and cellular techniques to understand how diverse regions of the nervous system are generated, including the cerebral cortex, the cerebellum, the spinal cord and the hypothalamus. For example, within the cerebral cortex, we are investigating how the NFI family of transcription factors mediate NSC differentiation, and how mutations to the NFI family culminate in macrocephaly, and disorders such as Malan syndrome. Moreover, we are using mice lacking the gene Nsd1 (a histone modifying protein) to investigate the development of a human syndrome known as Sotos syndrome, which is also characterised by macrocephaly. In collaboration with Mikael Boden (SCMB), we are also investigating how changes to chromatin landscapes mediate NSC differentiation, and developing bioinformatic tools to enhance the analysis of RNA-seq and ChIP-seq datasets. Collectively, this work will provide fundamental insights into neural development, as well as insights into human neurodevelopmental disorders that arise as a result of abnormal neural stem cell biology in utero.
Research impacts
The human brain is an incredibly complex organ, consisting of over 100 billion neurons, and even more glial cells. Further adding to this complexity is the fact that there are a wide variety of distinct neuronal subpopulations within the brain, each with different morphological characteristics, neurochemical properties and patterns of connectivity. Amazingly, nearly all of the cells within the brain are derived from a relatively small population of neural stem cells (NSCs) that proliferate, then differentiate, during embryogenesis. Understanding how NSC biology is coordinated, both spatially and temporally, to generate the mature brain remains one of the great challenges in biology. My vision is to reveal the mechanisms that control NSC differentiation within the developing brain, and to apply this knowledge to understand diseases caused by abnormal NSC differentiation, such as autism and hydrocephalus.
I have made a number of significant contributions to understanding how NSC differentiation is coordinated during neural development since starting my own group in late 2010. This work, which was supported by competitive fellowship (NHMRC Career Development Fellowship 2009-2012; ARC Future Fellowship 2013-2017) and grant funding (three NHMRC project grants as CIA; two ARC Discovery Projects as sole CI), has helped to elucidate the fundamental mechanisms underpinning neurogenesis within the neocortex, hippocampus and cerebellum. I have also defined critical molecular controllers of NSC quiescence, a cellular state that ensures the longevity of adult NSCs, as well as describing the behavioural consequences of aberrant adult neurogenesis. Finally, I have provided new insights into how abnormal stem cell biology can contribute to a range of neurodevelopmental disorders, as well as cancers of the brain and skin. The significance of my findings has been recognised by multiple awards for research excellence, from both national (e.g. 2018 Emerging Leader Award, Australian and New Zealand Society for Cell and Developmental Biology; 2010 AW Campbell Award, Australasian Neuroscience Society) and international agencies (2015 Innovator Award, Hydrocephalus Association; 2010 CJ Herrick Award, American Association for Anatomists). I now am in an ideal position to address aspects of two key questions in the field, namely, what are the transcriptomic and epigenomic factors that control the differentiation of NSCs during brain development, and how do deficits in this process contribute to disease?
I have published 111 manuscripts, over 70% of which have been as first or last author. These include manuscripts in leading jourals such as Nature, Nature Neuroscience, Neuron, The Journal of Neuroscience and Cerebral Cortex. For my full publication record, please visit my Orcid site
Works
Search Professor Michael Piper’s works on UQ eSpace
Featured
2014
Journal Article
NFIX regulates neural progenitor cell differentiation during hippocampal morphogenesis
Heng, Yee Hsieh Evelyn, McLeay, Robert C., Harvey, Tracey J., Smith, Aaron G., Barry, Guy, Cato, Kathleen, Plachez, Celine, Little, Erica, Mason, Sharon, Dixon, Chantelle, Gronostajski, Richard M., Bailey, Timothy L., Richards, Linda J. and Piper, Michael (2014). NFIX regulates neural progenitor cell differentiation during hippocampal morphogenesis. Cerebral Cortex, 24 (1), 261-279. doi: 10.1093/cercor/bhs307
Featured
2011
Journal Article
Transcription factor Lhx2 is necessary and sufficient to suppress astrogliogenesis and promote neurogenesis in the developing hippocampus
Subramanian, Lakshmi, Sarkar, Anindita, Shetty, Ashwin S., Muralidharan, Bhavana, Padmanabhan, Hari, Piper, Michael, Monuki, Edwin S., Bach, Ingolf, Gronostajski, Richard M., Richards, Linda J. and Tole, Shubha (2011). Transcription factor Lhx2 is necessary and sufficient to suppress astrogliogenesis and promote neurogenesis in the developing hippocampus. Proceedings of the National Academy of Sciences of the United States of America, 108 (27), E-265-E-274. doi: 10.1073/pnas.1101109108
Featured
2010
Journal Article
Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs
Zivraj, KH, Tung, YCL, Piper, M, Gumy, L, Fawcett, JW, Yeo, GSH and Holt, CE (2010). Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs. Journal of Neuroscience, 30 (46), 15464-15478. doi: 10.1523/JNEUROSCI.1800-10.2010
Featured
2010
Journal Article
NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1
Piper, Michael, Barry, Guy, Hawkins, John, Mason, Sharon, Lindwall, Charlotta, Little, Erica, Sarkar, Anindita, Smith, Aaron G., Moldrich, Randal X., Boyle, Glen M., Tole, Shubjha, Gronostajski, Richard M., Bailey, Timothy L. and Richards, Linda J. (2010). NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. Journal of Neuroscience, 30 (27), 9127-9139. doi: 10.1523/JNEUROSCI.6167-09.2010
Featured
2009
Journal Article
Neuropilin 1-Sema signaling regulates crossing of cingulate pioneering axons during development of the corpus callosum
Piper, Michael, Plachez, Celine, Zalucki, Oressia, Fothergill, Thomas, Goudreau, Guy, Erzurumlu, Reha, Gu, Chenghua and Richards, Linda J. (2009). Neuropilin 1-Sema signaling regulates crossing of cingulate pioneering axons during development of the corpus callosum. Cerebral Cortex, 19 (Supplement 1), i11-i21. doi: 10.1093/cercor/bhp027
Featured
2008
Journal Article
Specific glial populations regulate hippocampal morphogenesis
Barry, Guy, Michael Piper, Lindwall, Charlotta, Moldrich, Randal, Mason, Sharon, Little, Erica, Sarkar, Anindita, Tole, Shubha, Gronostajski, Richard M. and Richards, Linda J. (2008). Specific glial populations regulate hippocampal morphogenesis. The Journal of Neuroscience, 28 (47), 12328-12340. doi: 10.1523/JNEUROSCI.4000-08.2008
Featured
2008
Journal Article
NF-protocadherin and TAF1 regulate retinal axon initiation and elongation in vivo
Piper, Michael, Dwivedy, Asha, Leung, Louis, Bradley, Roger S. and Holt, Christine E. (2008). NF-protocadherin and TAF1 regulate retinal axon initiation and elongation in vivo. The Journal of Neuroscience, 28 (1), 100-105. doi: 10.1523/JNEUROSCI.4490-07.2008
Featured
2006
Journal Article
Signaling mechanisms underlying Slit2-induced collapse of Xenopus retinal growth cones
Piper, M., Anderson, R., Dwivedy, A., Weinl, C., van Horck, F., Leung, K. M., Cogill, E. and Holt, C. (2006). Signaling mechanisms underlying Slit2-induced collapse of Xenopus retinal growth cones. Neuron, 49 (2), 215-228. doi: 10.1016/j.neuron.2005.12.008
Featured
2005
Journal Article
The transcription factor Engrailed-2 guides retinal axons
Brunet, Isabelle, Weinl, Christine, Piper,Michael, Trembleau, Alain, Volovitch, Michel, Harris, William, Prochiantz, Alain and Holt, Christine (2005). The transcription factor Engrailed-2 guides retinal axons. Nature, 438 (7064), 94-98. doi: 10.1038/nature04110
Featured
2005
Journal Article
Endocytosis-dependent desensitization and protein synthesis-dependent resensitization in retinal growth cone adaptation
Piper, Michael, Salih, Saif, Weinl, Christine, Holt, Christine E. and Harris, William A. (2005). Endocytosis-dependent desensitization and protein synthesis-dependent resensitization in retinal growth cone adaptation. Nature Neuroscience, 8 (2), 179-186. doi: 10.1038/nn1380
2025
Journal Article
Systematic analysis of the transcriptional landscape of melanoma reveals drug-target expression plasticity
Balderson, Brad, Fane, Mitchell, Harvey, Tracey J., Piper, Michael, Smith, Aaron and Bodén, Mikael (2025). Systematic analysis of the transcriptional landscape of melanoma reveals drug-target expression plasticity. Briefings in Functional Genomics, 24 elad055. doi: 10.1093/bfgp/elad055
2024
Journal Article
Single cell transcriptomics of the cerebral cortex of mice lacking the PRC2 gene eed
Currey, Laura, Harris, Lachlan and Piper, Michael (2024). Single cell transcriptomics of the cerebral cortex of mice lacking the PRC2 gene eed. BMC Research Notes, 17 (1) 382. doi: 10.1186/s13104-024-07008-y
2024
Journal Article
Expression of the Hippo pathway effector, TEAD1, within the developing murine forebrain
Pelenyi, Alexandra, Atterton, Cooper, Jones, Justin, Currey, Laura, Al-Khalily, Majd, Wright, Lucinda, Kurniawan, Nyoman D., Thor, Stefan and Piper, Michael (2024). Expression of the Hippo pathway effector, TEAD1, within the developing murine forebrain. Gene Expression Patterns, 54 119384, 119384. doi: 10.1016/j.gep.2024.119384
2024
Journal Article
Polycomb repressive complex 2 is critical for mouse cortical glutamatergic neuron development
Currey, Laura, Mitchell, Benjamin, Al-Khalily, Majd, McElnea, Sarah-Jayne, Kozulin, Peter, Harkins, Danyon, Pelenyi, Alexandra, Fenlon, Laura, Suarez, Rodrigo, Kurniawan, Nyoman D, Burne, Thomas H, Harris, Lachlan, Thor, Stefan and Piper, Michael (2024). Polycomb repressive complex 2 is critical for mouse cortical glutamatergic neuron development. Cerebral Cortex, 34 (7) bhae268. doi: 10.1093/cercor/bhae268
2024
Journal Article
A protocol for high-resolution episcopic microscopy and 3D volumetric analyses of the adult mouse brain
Mitchell, Benjamin, Mu, Erica, Currey, Laura, Whitehead, Darryl, Walters, Shaun, Thor, Stefan, Kasherman, Maria and Piper, Michael (2024). A protocol for high-resolution episcopic microscopy and 3D volumetric analyses of the adult mouse brain. Neuroscience Letters, 824 137675, 1-6. doi: 10.1016/j.neulet.2024.137675
2024
Conference Publication
The Influence of b value and Resolution on MR Tractography and Connectome Construction in Adult Mouse Brain at 16.4 Tesla
Alkhalily, Majd, Currey, Laura, Piper, Michael and Kurniawan, Nyoman (2024). The Influence of b value and Resolution on MR Tractography and Connectome Construction in Adult Mouse Brain at 16.4 Tesla. 2023 ISMRM & ISMRT Annual Meeting & Exhibition, Toronto, Canada, 3-8 June 2023. Concord, CA United States: ISMRM. doi: 10.58530/2023/0226
2024
Conference Publication
Application of Diffusion MRI to Characterize Connectome Changes Associated with EED Ablation
Alkhalily, Majd, Currey, Laura, Piper, Michael and Kurniawan, Nyoman (2024). Application of Diffusion MRI to Characterize Connectome Changes Associated with EED Ablation. 2023 ISMRM & ISMRT Annual Meeting & Exhibition, Toronto, Canada, 3-8 June 2023. Concord, CA United States: ISMRM. doi: 10.58530/2023/2685
2023
Journal Article
Cellular and molecular functions of SETD2 in the central nervous system
Mitchell, Benjamin, Thor, Stefan and Piper, Michael (2023). Cellular and molecular functions of SETD2 in the central nervous system. Journal of Cell Science, 136 (21) jcs261406, 1-11. doi: 10.1242/jcs.261406
2023
Conference Publication
Polycomb Protein EED Regulates Identity Of Glutamatergic Neurons
Currey, Laura, Mitchell, Benjamin, Harris, Lachlan, Thor, Stefan and Piper, Michael (2023). Polycomb Protein EED Regulates Identity Of Glutamatergic Neurons. IBRO 11th World Congress of Neuroscience, Granada, Spain, 9-13 September 2023. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.ibneur.2023.08.045
2023
Journal Article
Cytocipher determines significantly different populations of cells in single cell RNA-seq data
Balderson, Brad, Piper, Michael, Thor, Stefan and Boden, Mikael (2023). Cytocipher determines significantly different populations of cells in single cell RNA-seq data. Bioinformatics, 39 (7) btad435. doi: 10.1093/bioinformatics/btad435
Funding
Current funding
Past funding
Supervision
Availability
- Professor Michael Piper is:
- Available for supervision
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Available projects
-
Understanding the drivers of neural stem cell differentiation
What are the mechanisms that control neural stem cell (NSC) differentiation during embryogenesis, and that enable the generation of the diverse suite of neurons and glia that comprise the brain? This is a key question in developmental neuroscience. My contribution to this field to date has been to reveal central transcriptional regulators that mediate NSC biology within the brain. Using rodent model systems, I demonstrated that transcription factors of the Nuclear Factor One (NFI) family mediate NSC proliferation and differentiation in the embryonic, postnatal and adult nervous system. This work has received international recognition, as evidenced by numerous invited international presentations and high-impact reviews (e.g. Trends in Cell Biology), and forms the framework around which the hypotheses of this program will be addressed.
I am interested in defining how NSC proliferation and differentiation is regulated at a transcriptional and epigenomic level within the developing nervous system. Using the developing mouse brain as a model system, we are using a suite of molecular and cellular techniques to understand how diverse regions of the nervous system are generated, including the cerebral cortex, the cerebellum, the spinal cord and the hypothalamus. For example, within the cerebral cortex, we are investigating how the NFI family of transcription factors mediate NSC differentiation, and how mutations to the NFI family culminate in macrocephaly, and disorders such as Malan syndrome. Moreover, we are using mice lacking the gene Nsd1(a histone modifying protein) to investigate the development of a human syndrome known as Sotos syndrome, which is also characterised by macrocephaly. In collaboration with Mikael Boden (SCMB), we are also investigating how changes to chromatin landscapes mediate NSC differentiation, and developing bioinformatic tools to enhance the analysis of RNA-seq and ChIP-seq datasets. Collectively, this work will provide fundamental insights into neural development, as well as insights into human neurodevelopmental disorders that arise as a result of abnormal neural stem cell biology in utero.
-
Adult neurogenesis
The birth of new neurons within the mature cerebral cortex, a process termed neurogenesis, plays a critical role in learning, memory and spatial navigation. We are investigating various aspects of adult neurogenesis in rodent models, such as neural stem cell quiescence . We are also interrogating the consequences of abnormal neurogenesis using behavioural tests for learning and memory.
We employ a range of transgenic mice to investigate adult neurogenesis, coupled with techniques ranging from immunocytochemistry, behavioural testing, analysis of axonal connectivity and genome-wide sequencing platforms. Given the critical roles that learning and memory play in our everyday lives, and the fact that neurogenesis within the adult brain diminishes with age, this research will provide fundamental insights into how this vital process is co-ordinated at a cellular and molecular level.
-
Identifying how abnormal neural stem cell biology contributes to disease
The importance of NSC biology to brain development is underscored by disorders associated with abnormal NSC differentiation, including autism, hydrocephalus and macrocephaly. Despite the role of aberrant NSC development to these disorders, our understanding of the cellular and molecular deficits that contribute to disease onset and progression remains limited. Recently, my work has begun to focus on these disorders. Moreover, as the transcriptional landscape of many cancers resembles that of stem cells during development, I am also applying my expertise to understand how abnormal transcriptional activity contributes to cancer progression. This approach has gained significant traction, as evidenced by international awards (2015 Innovator Award, Hydrocephalus Association) and grants (Simons Foundation Autism Research Initiative, 2018-2019; Cancer Council Queensland, 2016-2017) I have received.
-
Understanding the drivers of neural stem cell differentiation
What are the mechanisms that control neural stem cell (NSC) differentiation during embryogenesis, and that enable the generation of the diverse suite of neurons and glia that comprise the brain? This is a key question in developmental neuroscience. My contribution to this field to date has been to reveal central transcriptional regulators that mediate NSC biology within the brain. Using rodent model systems, I demonstrated that transcription factors of the Nuclear Factor One (NFI) family mediate NSC proliferation and differentiation in the embryonic, postnatal and adult nervous system. This work has received international recognition, as evidenced by numerous invited international presentations and high-impact reviews (e.g. Trends in Cell Biology), and forms the framework around which the hypotheses of this program will be addressed.
I am interested in defining how NSC proliferation and differentiation is regulated at a transcriptional and epigenomic level within the developing nervous system. Using the developing mouse brain as a model system, we are using a suite of molecular and cellular techniques to understand how diverse regions of the nervous system are generated, including the cerebral cortex, the cerebellum, the spinal cord and the hypothalamus. For example, within the cerebral cortex, we are investigating how the NFI family of transcription factors mediate NSC differentiation, and how mutations to the NFI family culminate in macrocephaly, and disorders such as Malan syndrome. Moreover, we are using mice lacking the gene Nsd1(a histone modifying protein) to investigate the development of a human syndrome known as Sotos syndrome, which is also characterised by macrocephaly. In collaboration with Mikael Boden (SCMB), we are also investigating how changes to chromatin landscapes mediate NSC differentiation, and developing bioinformatic tools to enhance the analysis of RNA-seq and ChIP-seq datasets. Collectively, this work will provide fundamental insights into neural development, as well as insights into human neurodevelopmental disorders that arise as a result of abnormal neural stem cell biology in utero.
-
Adult neurogenesis
The birth of new neurons within the mature cerebral cortex, a process termed neurogenesis, plays a critical role in learning, memory and spatial navigation. We are investigating various aspects of adult neurogenesis in rodent models, such as neural stem cell quiescence . We are also interrogating the consequences of abnormal neurogenesis using behavioural tests for learning and memory.
We employ a range of transgenic mice to investigate adult neurogenesis, coupled with techniques ranging from immunocytochemistry, behavioural testing, analysis of axonal connectivity and genome-wide sequencing platforms. Given the critical roles that learning and memory play in our everyday lives, and the fact that neurogenesis within the adult brain diminishes with age, this research will provide fundamental insights into how this vital process is co-ordinated at a cellular and molecular level.
-
Identifying how abnormal neural stem cell biology contributes to disease
The importance of NSC biology to brain development is underscored by disorders associated with abnormal NSC differentiation, including autism, hydrocephalus and macrocephaly. Despite the role of aberrant NSC development to these disorders, our understanding of the cellular and molecular deficits that contribute to disease onset and progression remains limited. Recently, my work has begun to focus on these disorders. Moreover, as the transcriptional landscape of many cancers resembles that of stem cells during development, I am also applying my expertise to understand how abnormal transcriptional activity contributes to cancer progression. This approach has gained significant traction, as evidenced by international awards (2015 Innovator Award, Hydrocephalus Association) and grants (Simons Foundation Autism Research Initiative, 2018-2019; Cancer Council Queensland, 2016-2017) I have received.
Supervision history
Current supervision
-
Doctor Philosophy
The role of transcription factor Tead1 in cortical development
Principal Advisor
Other advisors: Professor Stefan Thor
-
Doctor Philosophy
How SETD2 shapes cortical development
Principal Advisor
Other advisors: Professor Mikael Boden, Professor Stefan Thor
-
Doctor Philosophy
How epigenetic modifiers regulate brain size
Principal Advisor
Other advisors: Professor Stefan Thor
-
Doctor Philosophy
Understanding how PCP signalling drives junctional neural tube formation
Associate Advisor
Other advisors: Dr Yanina Alvarez, Dr Mel White
-
Doctor Philosophy
Decoding the genetic pathways governing cell diversity in the mammalian hypothalamus
Associate Advisor
Other advisors: Professor Mikael Boden, Professor Stefan Thor
-
Doctor Philosophy
Developing an in vitro human sleep system
Associate Advisor
Other advisors: Professor Ernst Wolvetang, Professor Stefan Thor
-
Doctor Philosophy
Unmasking the function of the transcription factor NFIX in mammalian gonads
Associate Advisor
Other advisors: Dr Cassy Spiller, Professor Josephine Bowles
-
Doctor Philosophy
Generating hypothalamic neurons from human stem cells
Associate Advisor
Other advisors: Professor Ernst Wolvetang, Professor Stefan Thor
-
Doctor Philosophy
Generating complex brain organoids from human stem cells
Associate Advisor
Other advisors: Professor Ernst Wolvetang, Professor Stefan Thor
-
Doctor Philosophy
Using Statistical Models to Integrate Epigenetic Information by Distinguishing Sources of Variability
Associate Advisor
Other advisors: Professor Mikael Boden
-
Doctor Philosophy
Direct targeting of quiescent cancer stem cells.
Associate Advisor
-
Doctor Philosophy
To identify novel regulators of quiescence in neural stem cells (NSCs) and glioma stem cells.
Associate Advisor
-
Doctor Philosophy
Unmasking the function of the transcription factor NFIX in mammalian gonads
Associate Advisor
Other advisors: Dr Cassy Spiller, Professor Josephine Bowles
Completed supervision
-
2023
Doctor Philosophy
The role of the Polycomb protein Eed in the mouse cerebral cortex
Principal Advisor
Other advisors: Professor Stefan Thor
-
2022
Doctor Philosophy
Understanding the role of nuclear factor one X (NFIX) in ependymal differentiation and maintenance
Principal Advisor
-
2020
Doctor Philosophy
Molecular mechanisms underlying malformations of cortical development
Principal Advisor
-
2020
Doctor Philosophy
The role of Nuclear Factor One transcription factors in cerebellar development
Principal Advisor
Other advisors: Professor Brandon Wainwright
-
2019
Doctor Philosophy
The investigation of hydrocephalus in mice lacking the transcription factor NFIX
Principal Advisor
-
2017
Doctor Philosophy
The function of NFIX during developmental and adult neurogenesis
Principal Advisor
Other advisors: Professor Thomas Burne
-
2017
Doctor Philosophy
Analysis of the Role of Crim1 in Heart Development
Principal Advisor
Other advisors: Professor Wally Thomas
-
2014
Doctor Philosophy
The role of Nfix in the development of the embryonic and postnatal cerebral cortex
Principal Advisor
-
2025
Doctor Philosophy
Unmasking the function of the transcription factor NFIX in mammalian gonads
Associate Advisor
Other advisors: Dr Cassy Spiller, Professor Josephine Bowles
-
2024
Doctor Philosophy
Development of Diffusion MRI and Tractography Protocols to Characterise Mouse Brain Development
Associate Advisor
Other advisors: Dr Nyoman Kurniawan
-
2023
Doctor Philosophy
Aberrant ependymal development and the formation of hydrocephalus
Associate Advisor
Other advisors: Professor Helen Cooper
-
2023
Doctor Philosophy
Cell Type Definition from Single Cell RNA-seq
Associate Advisor
Other advisors: Professor Jessica Mar, Professor Stefan Thor, Professor Mikael Boden
-
2021
Doctor Philosophy
Mobilisation and Regulation of L1 Retrotransposons in Mammalian Development
Associate Advisor
Other advisors: Dr Sandra Richardson, Professor Geoff Faulkner
-
2021
Doctor Philosophy
Endocytosis Inhibition to Improve Responses to Antibody Dependent Cellular Cytotoxicity-Mediating Antibodies
Associate Advisor
Other advisors: Professor Ben Panizza, Associate Professor James Wells, Professor Fiona Simpson
-
2020
Doctor Philosophy
NOVEL THERAPEUTIC STRATEGIES FOR THE TREATMENT OF PAEDIATRIC BRAIN CANCER
Associate Advisor
-
2020
Doctor Philosophy
p75 neurotrophin receptor function in brain development
Associate Advisor
Other advisors: Professor Elizabeth Coulson
-
2020
Doctor Philosophy
A computational analysis of transcription factor interactions and binding guided by epigenetics
Associate Advisor
Other advisors: Professor Brandon Wainwright, Professor Mikael Boden
-
2018
Master Philosophy
Investigating the role of Dscam2 in the Drosophila mushroom bodies
Associate Advisor
Other advisors: Associate Professor Sean Millard
-
2012
Doctor Philosophy
The Role of Nuclear Factor One (NFI) in Cortical Development
Associate Advisor
-
2010
Doctor Philosophy
Role of Slit and Robo in the development of midline glia and corpus callosum
Associate Advisor
Other advisors: Professor Helen Cooper
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