Overview
Availability
- Professor Geoff Faulkner is:
- Available for supervision
Qualifications
- Bachelor (Honours) of Science (Advanced), The University of Queensland
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Geoff Faulkner’s works on UQ eSpace
2025
Journal Article
OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide
Sepulveda, Hugo, Li, Xiang, Arteaga-Vazquez, Leo J., López-Moyado, Isaac F., Brunelli, Melina, Hernández-Espinosa, Lot, Yue, Xiaojing, Angel, J. Carlos, Brown, Caitlin, Dong, Zhen, Jansz, Natasha, Puddu, Fabio, Modat, Aurélie, Scotcher, Jamie, Creed, Páidí, Kennedy, Patrick H., Manriquez-Rodriguez, Cindy, Myers, Samuel A., Crawford, Robert, Faulkner, Geoffrey J. and Rao, Anjana (2025). OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide. Nature Structural & Molecular Biology 3, 1-15. doi: 10.1038/s41594-025-01505-9
2025
Journal Article
A mutant ASXL1-BAP1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia
Dong, Zhen, Sepulveda, Hugo, Arteaga-Vazquez, Leo J., Blouin, Chad, Fernandez, Jenna, Binder, Moritz, Chou, Wen-Chien, Tien, Hwei-Fang, Patnaik, Mrinal M., Faulkner, Geoffrey J., Myers, Samuel A. and Rao, Anjana (2025). A mutant ASXL1-BAP1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia. Proceedings of the National Academy of Sciences, 122 (1) e2413302121, 1. doi: 10.1073/pnas.2413302121
2024
Journal Article
Chromatin-based memory as a self-stabilizing influence on cell identity
Bell, Charles C., Faulkner, Geoffrey J. and Gilan, Omer (2024). Chromatin-based memory as a self-stabilizing influence on cell identity. Genome Biology, 25 (1) 320. doi: 10.1186/s13059-024-03461-x
2024
Journal Article
Two HUSH complexes connect a direct LINE to innate immunity
Faulkner, Geoffrey J. (2024). Two HUSH complexes connect a direct LINE to innate immunity. Molecular Cell, 84 (15), 2801-2803. doi: 10.1016/j.molcel.2024.07.010
2024
Journal Article
LINE-1 retrotransposons contribute to mouse PV interneuron development
Bodea, Gabriela O., Botto, Juan M., Ferreiro, Maria E., Sanchez-Luque, Francisco J., de los Rios Barreda, Jose, Rasmussen, Jay, Rahman, Muhammed A., Fenlon, Laura R., Jansz, Natasha, Gubert, Carolina, Gerdes, Patricia, Bodea, Liviu-Gabriel, Ajjikuttira, Prabha, Da Costa Guevara, Darwin J., Cumner, Linda, Bell, Charles C., Kozulin, Peter, Billon, Victor, Morell, Santiago, Kempen, Marie-Jeanne H. C., Love, Chloe J., Saha, Karabi, Palmer, Lucy M., Ewing, Adam D., Jhaveri, Dhanisha J., Richardson, Sandra R., Hannan, Anthony J. and Faulkner, Geoffrey J. (2024). LINE-1 retrotransposons contribute to mouse PV interneuron development. Nature Neuroscience, 27 (7), 1-34. doi: 10.1038/s41593-024-01650-2
2024
Journal Article
Comparative cofactor screens show the influence of transactivation domains and core promoters on the mechanisms of transcription
Bell, Charles C., Balic, Jesse J., Talarmain, Laure, Gillespie, Andrea, Scolamiero, Laura, Lam, Enid Y. N., Ang, Ching-Seng, Faulkner, Geoffrey J., Gilan, Omer and Dawson, Mark A. (2024). Comparative cofactor screens show the influence of transactivation domains and core promoters on the mechanisms of transcription. Nature Genetics, 56 (6), 1181-1192. doi: 10.1038/s41588-024-01749-z
2024
Journal Article
Viral genome sequencing methods: benefits and pitfalls of current approaches
Jansz, Natasha and Faulkner, Geoffrey J. (2024). Viral genome sequencing methods: benefits and pitfalls of current approaches. Biochemical Society Transactions, 52 (3), 1431-1447. doi: 10.1042/bst20231322
2024
Journal Article
Stimulation of the muscarinic receptor M4 regulates neural precursor cell proliferation and promotes adult hippocampal neurogenesis
Madrid, Lidia I., Hafey, Katelyn, Bandhavkar, Saurabh, Bodea, Gabriela O., Jimenez-Martin, Javier, Milne, Michael, Walker, Tara L., Faulkner, Geoffrey J., Coulson, Elizabeth J. and Jhaveri, Dhanisha J. (2024). Stimulation of the muscarinic receptor M4 regulates neural precursor cell proliferation and promotes adult hippocampal neurogenesis. Development, 151 (1) dev201835, 1-13. doi: 10.1242/dev.201835
Featured
2023
Journal Article
HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function
Friedman, Clayton E., Cheetham, Seth W., Negi, Sumedha, Mills, Richard J., Ogawa, Masahito, Redd, Meredith A., Chiu, Han Sheng, Shen, Sophie, Sun, Yuliangzi, Mizikovsky, Dalia, Bouveret, Romaric, Chen, Xiaoli, Voges, Holly K., Paterson, Scott, De Angelis, Jessica E., Andersen, Stacey B., Cao, Yuanzhao, Wu, Yang, Jafrani, Yohaann M.A., Yoon, Sohye, Faulkner, Geoffrey J., Smith, Kelly A., Porrello, Enzo, Harvey, Richard P., Hogan, Benjamin M., Nguyen, Quan, Zeng, Jian, Kikuchi, Kazu, Hudson, James E. and Palpant, Nathan J. (2023). HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function. Developmental Cell, 59 (1), 91-107.e1. doi: 10.1016/j.devcel.2023.11.012
2023
Journal Article
Locus-resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic development
Gerdes, Patricia, Chan, Dorothy, Lundberg, Mischa, Sanchez-Luque, Francisco J., Bodea, Gabriela O., Ewing, Adam D., Faulkner, Geoffrey J. and Richardson, Sandra R. (2023). Locus-resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic development. Genome Research, 33 (9), 1465-1481. doi: 10.1101/gr.278003.123
2023
Journal Article
Transient naive reprogramming corrects hiPS cells functionally and epigenetically
Buckberry, Sam, Liu, Xiaodong, Poppe, Daniel, Tan, Jia Ping, Sun, Guizhi, Chen, Joseph, Nguyen, Trung Viet, de Mendoza, Alex, Pflueger, Jahnvi, Frazer, Thomas, Vargas-Landín, Dulce B., Paynter, Jacob M., Smits, Nathan, Liu, Ning, Ouyang, John F., Rossello, Fernando J., Chy, Hun S., Rackham, Owen J. L., Laslett, Andrew L., Breen, James, Faulkner, Geoffrey J., Nefzger, Christian M., Polo, Jose M. and Lister, Ryan (2023). Transient naive reprogramming corrects hiPS cells functionally and epigenetically. Nature, 620 (7975), 863-872. doi: 10.1038/s41586-023-06424-7
2023
Journal Article
Endogenous retroviruses can propagate TDP-43 proteinopathy
Ferreiro, Maria E. and Faulkner, Geoffrey J. (2023). Endogenous retroviruses can propagate TDP-43 proteinopathy. Trends in Neurosciences, 46 (6), 413-414. doi: 10.1016/j.tins.2023.03.011
2023
Journal Article
Elevated L1 expression in ataxia telangiectasia likely explained by an RNA-seq batch effect
Faulkner, Geoffrey J. (2023). Elevated L1 expression in ataxia telangiectasia likely explained by an RNA-seq batch effect. Neuron, 111 (5), 610-611. doi: 10.1016/j.neuron.2023.02.007
2023
Journal Article
Single-neuron whole genome sequencing identifies increased somatic mutation burden in Alzheimer's disease related genes
Li, Zongchang, Min, Shishi, Alliey-Rodriguez, Ney, Giase, Gina, Cheng, Lijun, Craig, David Wesley, Faulkner, Geoffrey J., Asif, Huma, Liu, Chunyu and Gershon, Elliot S. (2023). Single-neuron whole genome sequencing identifies increased somatic mutation burden in Alzheimer's disease related genes. Neurobiology of Aging, 123, 222-232. doi: 10.1016/j.neurobiolaging.2022.12.002
2023
Journal Article
The complexity of transferring genetic information
Strader, Lucia C., Staller, Max V., Willis, Anne E., Faulkner, Geoffrey J., Beggs, Jean D. and Cech, Thomas R. (2023). The complexity of transferring genetic information. Molecular Cell, 83 (3), 320-323. doi: 10.1016/j.molcel.2023.01.002
2023
Journal Article
Impact of retrotransposon protein L1 ORF1p expression on oncogenic pathways in hepatocellular carcinoma: the role of cytoplasmic PIN1 upregulation
Zadran, Bassier, Sudhindar, Praveen Dhondurao, Wainwright, Daniel, Bury, Yvonne, Luli, Saimir, Howarth, Rachel, McCain, Misti Vanette, Watson, Robyn, Huet, Hannah, Palinkas, Fanni, Palmini, Rolando Berlinguer, Casement, John, Mann, Derek A., Oakley, Fiona, Lunec, John, Reeves, Helen, Faulkner, Geoffrey J. and Shukla, Ruchi (2023). Impact of retrotransposon protein L1 ORF1p expression on oncogenic pathways in hepatocellular carcinoma: the role of cytoplasmic PIN1 upregulation. British Journal of Cancer, 128 (7), 1236-1248. doi: 10.1038/s41416-023-02154-9
2022
Journal Article
Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cells
Gerdes, Patricia, Lim, Sue Mei, Ewing, Adam D., Larcombe, Michael R., Chan, Dorothy, Sanchez-Luque, Francisco J., Walker, Lucinda, Carleton, Alexander L., James, Cini, Knaupp, Anja S., Carreira, Patricia E., Nefzger, Christian M., Lister, Ryan, Richardson, Sandra R., Polo, Jose M. and Faulkner, Geoffrey J. (2022). Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cells. Nature Communications, 13 (1) 7470, 1-18. doi: 10.1038/s41467-022-35180-x
2022
Journal Article
Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7)
Grapotte, Mathys, Saraswat, Manu, Bessière, Chloé, Menichelli, Christophe, Ramilowski, Jordan A., Severin, Jessica, Hayashizaki, Yoshihide, Itoh, Masayoshi, Tagami, Michihira, Murata, Mitsuyoshi, Kojima-Ishiyama, Miki, Noma, Shohei, Noguchi, Shuhei, Kasukawa, Takeya, Hasegawa, Akira, Suzuki, Harukazu, Nishiyori-Sueki, Hiromi, Frith, Martin C., Abugessaisa, Imad, Aitken, Stuart, Aken, Bronwen L., Alam, Intikhab, Alam, Tanvir, Alasiri, Rami, Alhendi, Ahmad M. N., Alinejad-Rokny, Hamid, Alvarez, Mariano J., Andersson, Robin, Arakawa, Takahiro ... Lecellier, Charles-Henri (2022). Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7). Nature Communications, 13 (1) 1200. doi: 10.1038/s41467-022-28758-y
2022
Book Chapter
Nanopore Sequencing to Identify Transposable Element Insertions and Their Epigenetic Modifications
Smits, Nathan and Faulkner, Geoffrey J. (2022). Nanopore Sequencing to Identify Transposable Element Insertions and Their Epigenetic Modifications. Transposable Elements: Methods and Protocols. (pp. 151-171) New York, NY United States: Springer. doi: 10.1007/978-1-0716-2883-6_9
2022
Journal Article
Endogenous retrovirus expression during fruitfly metamorphosis enhances adult viral immunity
Botto, Juan M. and Faulkner, Geoffrey J. (2022). Endogenous retrovirus expression during fruitfly metamorphosis enhances adult viral immunity. Nature Genetics, 54 (12), 1765-1767. doi: 10.1038/s41588-022-01209-6
Funding
Current funding
Supervision
Availability
- Professor Geoff Faulkner is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Understanding LINE-1 retrotransposon activity in healthy and diseased dopaminergic neurons
Principal Advisor
Other advisors: Dr Gabriela-Oana Bodea
-
Doctor Philosophy
Rewiring transcription in solid tumours by targeting transposable elements
Principal Advisor
-
Doctor Philosophy
Understanding LINE-1 retrotransposon activity in healthy and diseased dopaminergic neurons
Principal Advisor
Other advisors: Dr Gabriela-Oana Bodea
-
Doctor Philosophy
The transposable element regulatory landscape of implantation and trophoblast differentiation
Principal Advisor
-
Doctor Philosophy
L1 retrotransposon regulation in the mammalian neuronal lineage
Principal Advisor
Other advisors: Dr Sandra Richardson, Dr Gabriela-Oana Bodea
-
Doctor Philosophy
Visualising genetic mosaicism during development
Principal Advisor
Other advisors: Dr Sandra Richardson, Dr Gabriela-Oana Bodea
-
Doctor Philosophy
Investigations into genetic aberrations underlying recurrent ovarian cancer
Associate Advisor
-
Doctor Philosophy
Developing genomic profiling techniques using synthetic DNA methylases
Associate Advisor
Other advisors: Associate Professor Seth Cheetham
-
Doctor Philosophy
Jumping Genes in Mammalian Development
Associate Advisor
Other advisors: Dr Sandra Richardson
Completed supervision
-
2024
Doctor Philosophy
Understanding LINE-1 retrotransposon activity in healthy and diseased dopaminergic neurons
Principal Advisor
Other advisors: Dr Gabriela-Oana Bodea
-
2023
Doctor Philosophy
Nanopore Sequencing for Mobile Element Research: The Long and Short of It
Principal Advisor
Other advisors: Associate Professor Seth Cheetham, Associate Professor Adam Ewing
-
2021
Doctor Philosophy
Mobilisation and Regulation of L1 Retrotransposons in Mammalian Development
Principal Advisor
Other advisors: Professor Michael Piper, Dr Sandra Richardson
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2019
Doctor Philosophy
L1 is dynamic during neurogenesis
Principal Advisor
Other advisors: Professor Ernst Wolvetang, Dr Sandra Richardson
-
2016
Doctor Philosophy
LINE-1 retrotransposition and somatic genome instability in serous ovarian carcinoma
Principal Advisor
-
2024
Doctor Philosophy
Developing genomic profiling techniques using synthetic DNA methylases
Associate Advisor
Other advisors: Associate Professor Seth Cheetham
-
2022
Doctor Philosophy
Functional coding and noncoding pseudogenes in the human genome
Associate Advisor
Other advisors: Associate Professor Adam Ewing, Associate Professor Seth Cheetham
-
2021
Doctor Philosophy
Identifying Novel Regulators of Adult Hippocampal Neurogenesis.
Associate Advisor
Media
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