Professor

Geoff Faulkner

Email: 
Phone: 
+61 7 334 66300

Availability

Professor Geoff Faulkner is:
Available for supervision

Qualifications

  • Bachelor (Honours) of Science (Advanced), The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Search Professor Geoff Faulkner’s works on UQ eSpace

103 works between 2003 and 2024
All (103) Journal Article (89) Book Chapter (6) Conference Publication (7) Other Outputs (1)

1 - 20 of 103 works

2024

Journal Article

Two HUSH complexes connect a direct LINE to innate immunity

Faulkner, Geoffrey J. (2024). Two HUSH complexes connect a direct LINE to innate immunity. Molecular Cell, 84 (15), 2801-2803. doi: 10.1016/j.molcel.2024.07.010

Two HUSH complexes connect a direct LINE to innate immunity

Featured

2024

Journal Article

LINE-1 retrotransposons contribute to mouse PV interneuron development

Bodea, Gabriela O., Botto, Juan M., Ferreiro, Maria E., Sanchez-Luque, Francisco J., de los Rios Barreda, Jose, Rasmussen, Jay, Rahman, Muhammed A., Fenlon, Laura R., Jansz, Natasha, Gubert, Carolina, Gerdes, Patricia, Bodea, Liviu-Gabriel, Ajjikuttira, Prabha, Da Costa Guevara, Darwin J., Cumner, Linda, Bell, Charles C., Kozulin, Peter, Billon, Victor, Morell, Santiago, Kempen, Marie-Jeanne H. C., Love, Chloe J., Saha, Karabi, Palmer, Lucy M., Ewing, Adam D., Jhaveri, Dhanisha J., Richardson, Sandra R., Hannan, Anthony J. and Faulkner, Geoffrey J. (2024). LINE-1 retrotransposons contribute to mouse PV interneuron development. Nature Neuroscience, 27 (7), 1-34. doi: 10.1038/s41593-024-01650-2

LINE-1 retrotransposons contribute to mouse PV interneuron development

2024

Journal Article

Comparative cofactor screens show the influence of transactivation domains and core promoters on the mechanisms of transcription

Bell, Charles C., Balic, Jesse J., Talarmain, Laure, Gillespie, Andrea, Scolamiero, Laura, Lam, Enid Y. N., Ang, Ching-Seng, Faulkner, Geoffrey J., Gilan, Omer and Dawson, Mark A. (2024). Comparative cofactor screens show the influence of transactivation domains and core promoters on the mechanisms of transcription. Nature Genetics, 56 (6), 1181-1192. doi: 10.1038/s41588-024-01749-z

Comparative cofactor screens show the influence of transactivation domains and core promoters on the mechanisms of transcription

2024

Journal Article

Viral genome sequencing methods: benefits and pitfalls of current approaches

Jansz, Natasha and Faulkner, Geoffrey J. (2024). Viral genome sequencing methods: benefits and pitfalls of current approaches. Biochemical Society Transactions, 52 (3), 1431-1447. doi: 10.1042/bst20231322

Viral genome sequencing methods: benefits and pitfalls of current approaches

2024

Journal Article

Stimulation of the muscarinic receptor M4 regulates neural precursor cell proliferation and promotes adult hippocampal neurogenesis

Madrid, Lidia I., Hafey, Katelyn, Bandhavkar, Saurabh, Bodea, Gabriela O., Jimenez-Martin, Javier, Milne, Michael, Walker, Tara L., Faulkner, Geoffrey J., Coulson, Elizabeth J. and Jhaveri, Dhanisha J. (2024). Stimulation of the muscarinic receptor M4 regulates neural precursor cell proliferation and promotes adult hippocampal neurogenesis. Development, 151 (1) dev201835, 1-13. doi: 10.1242/dev.201835

Stimulation of the muscarinic receptor M4 regulates neural precursor cell proliferation and promotes adult hippocampal neurogenesis

2023

Journal Article

HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function

Friedman, Clayton E., Cheetham, Seth W., Negi, Sumedha, Mills, Richard J., Ogawa, Masahito, Redd, Meredith A., Chiu, Han Sheng, Shen, Sophie, Sun, Yuliangzi, Mizikovsky, Dalia, Bouveret, Romaric, Chen, Xiaoli, Voges, Holly K., Paterson, Scott, De Angelis, Jessica E., Andersen, Stacey B., Cao, Yuanzhao, Wu, Yang, Jafrani, Yohaann M.A., Yoon, Sohye, Faulkner, Geoffrey J., Smith, Kelly A., Porrello, Enzo, Harvey, Richard P., Hogan, Benjamin M., Nguyen, Quan, Zeng, Jian, Kikuchi, Kazu, Hudson, James E. and Palpant, Nathan J. (2023). HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function. Developmental Cell, 59 (1), 91-107.e1. doi: 10.1016/j.devcel.2023.11.012

HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function

2023

Journal Article

Locus-resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic development

Gerdes, Patricia, Chan, Dorothy, Lundberg, Mischa, Sanchez-Luque, Francisco J., Bodea, Gabriela O., Ewing, Adam D., Faulkner, Geoffrey J. and Richardson, Sandra R. (2023). Locus-resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic development. Genome Research, 33 (9), 1465-1481. doi: 10.1101/gr.278003.123

Locus-resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic development

2023

Journal Article

Transient naive reprogramming corrects hiPS cells functionally and epigenetically

Buckberry, Sam, Liu, Xiaodong, Poppe, Daniel, Tan, Jia Ping, Sun, Guizhi, Chen, Joseph, Nguyen, Trung Viet, de Mendoza, Alex, Pflueger, Jahnvi, Frazer, Thomas, Vargas-Landín, Dulce B., Paynter, Jacob M., Smits, Nathan, Liu, Ning, Ouyang, John F., Rossello, Fernando J., Chy, Hun S., Rackham, Owen J. L., Laslett, Andrew L., Breen, James, Faulkner, Geoffrey J., Nefzger, Christian M., Polo, Jose M. and Lister, Ryan (2023). Transient naive reprogramming corrects hiPS cells functionally and epigenetically. Nature, 620 (7975), 863-872. doi: 10.1038/s41586-023-06424-7

Transient naive reprogramming corrects hiPS cells functionally and epigenetically

2023

Journal Article

Endogenous retroviruses can propagate TDP-43 proteinopathy

Ferreiro, Maria E. and Faulkner, Geoffrey J. (2023). Endogenous retroviruses can propagate TDP-43 proteinopathy. Trends in Neurosciences, 46 (6), 413-414. doi: 10.1016/j.tins.2023.03.011

Endogenous retroviruses can propagate TDP-43 proteinopathy

2023

Journal Article

Elevated L1 expression in ataxia telangiectasia likely explained by an RNA-seq batch effect

Faulkner, Geoffrey J. (2023). Elevated L1 expression in ataxia telangiectasia likely explained by an RNA-seq batch effect. Neuron, 111 (5), 610-611. doi: 10.1016/j.neuron.2023.02.007

Elevated L1 expression in ataxia telangiectasia likely explained by an RNA-seq batch effect

2023

Journal Article

Single-neuron whole genome sequencing identifies increased somatic mutation burden in Alzheimer's disease related genes

Li, Zongchang, Min, Shishi, Alliey-Rodriguez, Ney, Giase, Gina, Cheng, Lijun, Craig, David Wesley, Faulkner, Geoffrey J., Asif, Huma, Liu, Chunyu and Gershon, Elliot S. (2023). Single-neuron whole genome sequencing identifies increased somatic mutation burden in Alzheimer's disease related genes. Neurobiology of Aging, 123, 222-232. doi: 10.1016/j.neurobiolaging.2022.12.002

Single-neuron whole genome sequencing identifies increased somatic mutation burden in Alzheimer's disease related genes

2023

Journal Article

The complexity of transferring genetic information

Strader, Lucia C., Staller, Max V., Willis, Anne E., Faulkner, Geoffrey J., Beggs, Jean D. and Cech, Thomas R. (2023). The complexity of transferring genetic information. Molecular Cell, 83 (3), 320-323. doi: 10.1016/j.molcel.2023.01.002

The complexity of transferring genetic information

2023

Journal Article

Impact of retrotransposon protein L1 ORF1p expression on oncogenic pathways in hepatocellular carcinoma: the role of cytoplasmic PIN1 upregulation

Zadran, Bassier, Sudhindar, Praveen Dhondurao, Wainwright, Daniel, Bury, Yvonne, Luli, Saimir, Howarth, Rachel, McCain, Misti Vanette, Watson, Robyn, Huet, Hannah, Palinkas, Fanni, Palmini, Rolando Berlinguer, Casement, John, Mann, Derek A., Oakley, Fiona, Lunec, John, Reeves, Helen, Faulkner, Geoffrey J. and Shukla, Ruchi (2023). Impact of retrotransposon protein L1 ORF1p expression on oncogenic pathways in hepatocellular carcinoma: the role of cytoplasmic PIN1 upregulation. British Journal of Cancer, 128 (7), 1236-1248. doi: 10.1038/s41416-023-02154-9

Impact of retrotransposon protein L1 ORF1p expression on oncogenic pathways in hepatocellular carcinoma: the role of cytoplasmic PIN1 upregulation

2022

Journal Article

Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cells

Gerdes, Patricia, Lim, Sue Mei, Ewing, Adam D., Larcombe, Michael R., Chan, Dorothy, Sanchez-Luque, Francisco J., Walker, Lucinda, Carleton, Alexander L., James, Cini, Knaupp, Anja S., Carreira, Patricia E., Nefzger, Christian M., Lister, Ryan, Richardson, Sandra R., Polo, Jose M. and Faulkner, Geoffrey J. (2022). Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cells. Nature Communications, 13 (1) 7470, 1-18. doi: 10.1038/s41467-022-35180-x

Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cells

2022

Journal Article

Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7)

Grapotte, Mathys, Saraswat, Manu, Bessière, Chloé, Menichelli, Christophe, Ramilowski, Jordan A., Severin, Jessica, Hayashizaki, Yoshihide, Itoh, Masayoshi, Tagami, Michihira, Murata, Mitsuyoshi, Kojima-Ishiyama, Miki, Noma, Shohei, Noguchi, Shuhei, Kasukawa, Takeya, Hasegawa, Akira, Suzuki, Harukazu, Nishiyori-Sueki, Hiromi, Frith, Martin C., Abugessaisa, Imad, Aitken, Stuart, Aken, Bronwen L., Alam, Intikhab, Alam, Tanvir, Alasiri, Rami, Alhendi, Ahmad M. N., Alinejad-Rokny, Hamid, Alvarez, Mariano J., Andersson, Robin, Arakawa, Takahiro ... Lecellier, Charles-Henri (2022). Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7). Nature Communications, 13 (1) 1200. doi: 10.1038/s41467-022-28758-y

Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7)

2022

Book Chapter

Nanopore Sequencing to Identify Transposable Element Insertions and Their Epigenetic Modifications

Smits, Nathan and Faulkner, Geoffrey J. (2022). Nanopore Sequencing to Identify Transposable Element Insertions and Their Epigenetic Modifications. Transposable Elements: Methods and Protocols. (pp. 151-171) New York, NY United States: Springer. doi: 10.1007/978-1-0716-2883-6_9

Nanopore Sequencing to Identify Transposable Element Insertions and Their Epigenetic Modifications

2022

Journal Article

Endogenous retrovirus expression during fruitfly metamorphosis enhances adult viral immunity

Botto, Juan M. and Faulkner, Geoffrey J. (2022). Endogenous retrovirus expression during fruitfly metamorphosis enhances adult viral immunity. Nature Genetics, 54 (12), 1765-1767. doi: 10.1038/s41588-022-01209-6

Endogenous retrovirus expression during fruitfly metamorphosis enhances adult viral immunity

Featured

2022

Journal Article

Somatic retrotransposition in the developing rhesus macaque brain

Billon, Victor, Sanchez-Luque, Francisco J, Rasmussen, Jay, Bodea, Gabriela O, Gerhardt, Daniel J, Gerdes, Patricia, Cheetham, Seth W, Schauer, Stephanie N, Ajjikuttira, Prabha, Meyer, Thomas J, Layman, Cora E, Nevonen, Kimberly A, Jansz, Natasha, Garcia-Perez, Jose L, Richardson, Sandra R, Ewing, Adam D, Carbone, Lucia and Faulkner, Geoffrey J (2022). Somatic retrotransposition in the developing rhesus macaque brain. Genome Research, 32 (7), gr.276451.121-1314. doi: 10.1101/gr.276451.121

Somatic retrotransposition in the developing rhesus macaque brain

2022

Journal Article

HUSH, retrotransposon RNA, you're NEXT to decay

Faulkner, Geoffrey J. (2022). HUSH, retrotransposon RNA, you're NEXT to decay. Molecular Cell, 82 (9), 1610-1612. doi: 10.1016/j.molcel.2022.04.013

HUSH, retrotransposon RNA, you're NEXT to decay

2022

Journal Article

Retrotransposons: still mobile in humans

Faulkner, Geoffrey J. (2022). Retrotransposons: still mobile in humans. Nature Reviews Genetics, 23 (8), 458-459. doi: 10.1038/s41576-022-00485-6

Retrotransposons: still mobile in humans

Current funding

  • 2025 - 2029
    Mobile DNA decides neuronal fate in the normal and degenerative human brain
    NHMRC Investigator Grants
    Open grant
  • 2023 - 2027
    Using complex models of human trophoblast to study placental biology and disease (NHMRC Synergy grant led by University of Adelaide)
    University of Adelaide
    Open grant
  • 2020 - 2024
    Somatic genome mosaicism in human brain function and neurodegeneration
    NHMRC Investigator Grants
    Open grant

Past funding

  • 2021 - 2024
    Long-read genetic and epigenetic profiling in lung cancer for precision medicine
    Priority-driven Collaborative Cancer Research Scheme
    Open grant
  • 2020 - 2023
    Visualising genetic mosaicism during development
    ARC Discovery Projects
    Open grant
  • 2018 - 2020
    Hyperactive mobile DNA in schizophrenia
    NHMRC Project Grant
    Open grant
  • 2017 - 2019
    Does mobile DNA activity contribute to reproductive failure?
    NHMRC Project Grant
    Open grant
  • 2017 - 2019
    Epigenetic signatures of abnormal adult neurogenesis in Rett syndrome
    NHMRC Project Grant
    Open grant
  • 2017 - 2021
    The functional impact of neuronal L1 retrotransposition in learning and neurodegeneration
    CSL Limited
    Open grant
  • 2017 - 2018
    Unlocking the cellular determinants of retrotransposition
    ARC Discovery Projects
    Open grant
  • 2016 - 2018
    Does mobile DNA impact memory formation?
    NHMRC Project Grant
    Open grant
  • 2016 - 2020
    Neuronal genome mosaicism: a molecular component of cognition?
    NHMRC Research Fellowship
    Open grant
  • 2014 - 2017
    Somatic Mutations in Brain in Alzheimer's Disease (NIH Grant administered by the University of Chicago)
    University of Chicago, The
    Open grant
  • 2014 - 2016
    A three-tiered strategy to prevent destabilisation of the induced pluripotent stem cell genome by L1 retrotransposition
    NHMRC Project Grant
    Open grant
  • 2014 - 2016
    Harnessing endogenous L1-mediated mutagenesis to elucidate new candidate genes for liver cancer
    NHMRC Project Grant
    Open grant
  • 2013 - 2015
    Genetic consequences of mobile DNA activation in abnormal neurodevelopment
    NHMRC Project Grant
    Open grant
  • 2013 - 2015
    Mobile DNA as a contributor to human brain cancer
    NHMRC Project Grant
    Open grant
  • 2013 - 2015
    NHMRC Career Development Fellowship (R.D Wright Biomedical CDF Level1): L1 retrotransposition in human development and disease
    NHMRC Career Development Fellowship
    Open grant
  • 2013 - 2016
    Uncovering the impact of tandem repeat variation on both common and syndromic forms of paediatric obesity
    NHMRC Project Grant
    Open grant

Availability

Professor Geoff Faulkner is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    The transposable element regulatory landscape of implantation and trophoblast differentiation

    Principal Advisor

  • Doctor Philosophy

    Visualising genetic mosaicism during development

    Principal Advisor

    Other advisors: Dr Sandra Richardson, Dr Gabriela-Oana Bodea

  • Doctor Philosophy

    Understanding LINE-1 retrotransposon activity in healthy and diseased dopaminergic neurons

    Principal Advisor

    Other advisors: Dr Gabriela-Oana Bodea

  • Doctor Philosophy

    Rewiring transcription in solid tumours by targeting transposable elements

    Principal Advisor

  • Doctor Philosophy

    Jumping Genes in Mammalian Development

    Associate Advisor

    Other advisors: Dr Sandra Richardson

  • Doctor Philosophy

    Investigations into genetic aberrations underlying recurrent ovarian cancer

    Associate Advisor

    Other advisors: Honorary Professor John Hooper

  • Doctor Philosophy

    Developing genomic profiling techniques using synthetic DNA methylases

    Associate Advisor

    Other advisors: Dr Seth Cheetham

Completed supervision

Enquiries

For media enquiries about Professor Geoff Faulkner's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au