Dr Cassy Spiller
Dr

Cassy Spiller

Email: 

Availability

Dr Cassy Spiller is:
Available for supervision

Fields of research

Biological Sciences

Qualifications

  • Bachelor of Science, University of Newcastle
  • Doctor of Philosophy, The University of Queensland

Search Professor Cassy Spiller’s works on UQ eSpace

37 works between 2005 and 2024
All (37) Journal Article (30) Book Chapter (6) Other Outputs (1)

1 - 20 of 37 works

2024

Journal Article

Perinatal exposure to environmental chemicals that disrupt thyroid function can perturb testis development

Draskau, Monica K., Strand, Ida W., Davila, Raul, Ballegaard, Anne-Sofie R., Pedersen, Mikael, Ramhøj, Louise, Rising, Sofie, Tran, Kieu-mi, Axelstad, Marta, Bowles, Josephine, Rosenmai, Anna K., Spiller, Cassy M. and Svingen, Terje (2024). Perinatal exposure to environmental chemicals that disrupt thyroid function can perturb testis development. Environmental Pollution, 363 125117, 125117. doi: 10.1016/j.envpol.2024.125117

Perinatal exposure to environmental chemicals that disrupt thyroid function can perturb testis development

2023

Journal Article

Generation and characterization of a Ddx4‐iCre transgenic line for deletion in the germline beginning at genital ridge colonization

Burnet, Guillaume, Feng, Chun‐Wei Allen, Cheung, Ka Man Fiona, Bowles, Josephine and Spiller, Cassy M. (2023). Generation and characterization of a Ddx4‐iCre transgenic line for deletion in the germline beginning at genital ridge colonization. genesis, 61 (1-2) e23511, e23511. doi: 10.1002/dvg.23511

Generation and characterization of a Ddx4‐iCre transgenic line for deletion in the germline beginning at genital ridge colonization

2023

Book Chapter

Isolation and culture techniques for fetal mouse germ cells

Burnet, Guillaume, Bowles, Josephine and Spiller, Cassy M. (2023). Isolation and culture techniques for fetal mouse germ cells. Germline stem cells: methods and protocols. (pp. 221-231) edited by Michael Buszczak. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-3259-8_13

Isolation and culture techniques for fetal mouse germ cells

2022

Journal Article

Instructing mouse germ cells to adopt a female fate

Spiller, Cassy and Bowles, Josephine (2022). Instructing mouse germ cells to adopt a female fate. Sexual Development, 16 (5-6), 1-13. doi: 10.1159/000523763

Instructing mouse germ cells to adopt a female fate

2022

Journal Article

Deletion of NFIX results in defective progression through meiosis within the mouse testis

Davila, Raul Ayala, Spiller, Cassy, Harkins, Danyon, Harvey, Tracey, Jordan, Philip W., Gronostajski, Richard M., Piper, Michael and Bowles, Josephine (2022). Deletion of NFIX results in defective progression through meiosis within the mouse testis. Biology of Reproduction, 106 (6), 1191-1205. doi: 10.1093/biolre/ioac049

Deletion of NFIX results in defective progression through meiosis within the mouse testis

2022

Journal Article

AOP Key Event Relationship report: Linking decreased retinoic acid levels with disrupted meiosis in developing oocytes

Kam Draskau, Monica, Ravn Ballegaard, Anne-Sofie, Ramhøj, Louise, Bowles, Josephine, Svingen, Terje and Spiller, Cassy M. (2022). AOP Key Event Relationship report: Linking decreased retinoic acid levels with disrupted meiosis in developing oocytes. Current Research in Toxicology, 3 100069, 1-8. doi: 10.1016/j.crtox.2022.100069

AOP Key Event Relationship report: Linking decreased retinoic acid levels with disrupted meiosis in developing oocytes

2021

Journal Article

Identification of regulatory elements required for Stra8 expression, in fetal ovarian germ cells of the mouse

Feng, Chun-Wei, Burnet, Guillaume, Spiller, Cassy M., Cheung, Fiona Ka Man, Chawengsaksophak, Kallayanee, Koopman, Peter and Bowles, Josephine (2021). Identification of regulatory elements required for Stra8 expression, in fetal ovarian germ cells of the mouse. Development, 148 (5) dev194977, 1-13. doi: 10.1242/dev.194977

Identification of regulatory elements required for Stra8 expression, in fetal ovarian germ cells of the mouse

2020

Journal Article

CRIPTO and miR-371a-3p are serum biomarkers of testicular germ cell tumors and are detected in seminal plasma from azoospermic males

Spiller, Cassy M., Lobo, João, Boellaard, Willem P. A., Gillis, Ad J. M., Bowles, Josephine and Looijenga, Leendert H. J. (2020). CRIPTO and miR-371a-3p are serum biomarkers of testicular germ cell tumors and are detected in seminal plasma from azoospermic males. Cancers, 12 (3) 760, 760. doi: 10.3390/cancers12030760

CRIPTO and miR-371a-3p are serum biomarkers of testicular germ cell tumors and are detected in seminal plasma from azoospermic males

2020

Journal Article

Developmental biology meets toxicology: contributing reproductive mechanisms to build adverse outcome pathways

Draskau, Monica Kam, Spiller, Cassy M., Boberg, Julie, Bowles, Josephine and Svingen, Terje (2020). Developmental biology meets toxicology: contributing reproductive mechanisms to build adverse outcome pathways. Molecular Human Reproduction, 26 (2), 111-116. doi: 10.1093/molehr/gaaa001

Developmental biology meets toxicology: contributing reproductive mechanisms to build adverse outcome pathways

2019

Book Chapter

Sexually dimorphic germ cell identity in mammals

Spiller, Cassy and Bowles, Josephine (2019). Sexually dimorphic germ cell identity in mammals. Sex determination in vertebrates. (pp. 253-288) Maryland Heights, MO, United States: Academic Press. doi: 10.1016/bs.ctdb.2019.01.011

Sexually dimorphic germ cell identity in mammals

2018

Journal Article

Retinoic acid antagonizes testis development in mice

Bowles, Josephine, Feng, Chun-Wei, Ineson, Jessica, Miles, Kim, Spiller, Cassy M., Harley, Vincent R., Sinclair, Andrew H. and Koopman, Peter (2018). Retinoic acid antagonizes testis development in mice. Cell Reports, 24 (5), 1330-1341. doi: 10.1016/j.celrep.2018.06.111

Retinoic acid antagonizes testis development in mice

2018

Journal Article

Transcriptomic analysis of mRNA expression and alternative splicing during mouse sex determination

Zhao, Liang, Wang, Chenwei, Lehman, Melanie L., He, Mingyu, An, Jiyuan, Svingen, Terje, Spiller, Cassy M., Ng, Ee Ting, Nelson, Colleen C. and Koopman, Peter (2018). Transcriptomic analysis of mRNA expression and alternative splicing during mouse sex determination. Molecular and Cellular Endocrinology, 478, 84-96. doi: 10.1016/j.mce.2018.07.010

Transcriptomic analysis of mRNA expression and alternative splicing during mouse sex determination

2017

Journal Article

SOX30 is required for male fertility in mice

Feng, Chun-Wei Allen, Spiller, Cassy, Merriner, Donna J., O'Bryan, Moira K., Bowles, Josephine and Koopman, Peter (2017). SOX30 is required for male fertility in mice. Scientific Reports, 7 (1) 17619, 1-12. doi: 10.1038/s41598-017-17854-5

SOX30 is required for male fertility in mice

2017

Journal Article

Sex Determination in the Mammalian Germline

Spiller, Cassy, Koopman, Peter and Bowles, Josephine (2017). Sex Determination in the Mammalian Germline. Annual Review of Genetics, 51 (1), 265-285. doi: 10.1146/annurev-genet-120215-035449

Sex Determination in the Mammalian Germline

2017

Journal Article

Regulation of fetal male germ cell development by members of the TGFβ superfamily

Spiller, Cassy, Burnet, Guillaume and Bowles, Josephine (2017). Regulation of fetal male germ cell development by members of the TGFβ superfamily. Stem cell research, 24, 174-180. doi: 10.1016/j.scr.2017.07.016

Regulation of fetal male germ cell development by members of the TGFβ superfamily

2017

Journal Article

Germ cell neoplasia in situ: the precursor cell for invasive germ cell tumors of the testis

Spiller, Cassy M. and Bowles, Josephine (2017). Germ cell neoplasia in situ: the precursor cell for invasive germ cell tumors of the testis. International Journal of Biochemistry & Cell Biology, 86, 22-25. doi: 10.1016/j.bioce1.2017.03.004

Germ cell neoplasia in situ: the precursor cell for invasive germ cell tumors of the testis

2017

Journal Article

Mice lacking Hbp1 function are viable and fertile

Spiller, Cassy M., Wilhelm, Dagmar, Jans, David A., Bowles, Josephine and Koopman, Peter (2017). Mice lacking Hbp1 function are viable and fertile. PLoS One, 12 (1) e0170576, e0170576. doi: 10.1371/journal.pone.0170576

Mice lacking Hbp1 function are viable and fertile

2017

Book Chapter

Mouse fetal germ cell isolation and culture techniques

Spiller, Cassy M., Burnet, Guillaume and Bowles, Josephine (2017). Mouse fetal germ cell isolation and culture techniques. Germline stem cells. (pp. 173-183) edited by Michael Buszczak. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-4017-2_13

Mouse fetal germ cell isolation and culture techniques

2016

Journal Article

Cripto: expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors

Spiller, Cassy M., Gillis, Ad J. M., Burnet, Guillaume, Stoop, Hans, Koopman, Peter, Bowles, Josephine and Looijenga, Leendert H. J. (2016). Cripto: expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors. Molecular Oncology, 10 (4), 526-537. doi: 10.1016/j.molonc.2015.11.003

Cripto: expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors

2016

Journal Article

ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries

Bowles, Josephine, Feng, Chun-Wei, Miles, Kim, Ineson, Jessica, Spiller, Cassy and Koopman, Peter (2016). ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries. Nature Communications, 7 (1) 10845, 10845.1-10845.8. doi: 10.1038/ncomms10845

ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries

Past funding

  • 2023 - 2024
    Characterisation of a possible new mouse model of type II human germ cell cancer
    Society for Reproductive Biology
    Open grant
  • 2023 - 2024
    The Brain-Ovary connection: identification of a novel regulator of female reproductive function
    Repro Grants
    Open grant
  • 2021 - 2023
    Can inhalational general anaesthetic exposure during pregnancy affect non-genetic heritable elements in fetal germs cells in such a way as to engender pathology in offspring,
    Silicon Valley Community Foundation
    Open grant
  • 2020 - 2021
    Novel detection methods for adolescent germ cell cancers
    The Children's Hospital Foundation
    Open grant
  • 2020 - 2022
    Development of an ex vivo culture system to determine effects on reproductive endocrine disruption by environmental chemicals
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2020 - 2023
    How do mammalian germ cells transition from mitosis to meiosis?
    ARC Discovery Projects
    Open grant
  • 2019 - 2022
    Development of a non-invasive diagnostic and prognostic assay for adolescent testicular cancer
    The Kid's Cancer Project
    Open grant
  • 2018 - 2020
    Investigating spermatogonial stem cell allocation in the fetal testis
    ARC Discovery Projects
    Open grant
  • 2016
    Investigating new methods of treatments for chemotherapy-resistant testicular germ cell cancers
    Cancer Bequest Fund
    Open grant
  • 2016 - 2017
    Isolation and characterisation of fetal gonocytes with sustained pluripotent potential
    UQ Early Career Researcher
    Open grant
  • 2016 - 2019
    Molecular regulation of pluripotency in the mammalian germline
    NHMRC Project Grant
    Open grant
  • 2015 - 2016
    Dr Cassy Spiller - Maternity Funding (Advance Queensland Women's Academic Fund)
    Queensland Government Advance Queensland Women's Academic Fund
    Open grant
  • 2015 - 2016
    Nodal/Cripto signaling in germ cell development and tumorigenesis
    Cancer Council Queensland
    Open grant
  • 2014 - 2019
    CRIPTO as a diagnostic for testicular cancer
    UQ Postdoctoral Research Fellowship
    Open grant

Availability

Dr Cassy Spiller is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Enquiries

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