Associate Professor Josephine Bowles
Associate Professor

Josephine Bowles

Email: 
Phone: 
+61 7 336 53056

Availability

Associate Professor Josephine Bowles is:
Available for supervision

Fields of research

Biological Sciences Genetics

Qualifications

  • Bachelor (Honours) of Science (Advanced), The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Search Professor Josephine Bowles’s works on UQ eSpace

118 works between 1991 and 2024
All (118) Journal Article (97) Book Chapter (6) Conference Publication (15)

1 - 20 of 118 works

2024

Journal Article

Perinatal exposure to environmental chemicals that disrupt thyroid function can perturb testis development

Draskau, Monica K., Strand, Ida W., Davila, Raul, Ballegaard, Anne-Sofie R., Pedersen, Mikael, Ramhøj, Louise, Rising, Sofie, Tran, Kieu-mi, Axelstad, Marta, Bowles, Josephine, Rosenmai, Anna K., Spiller, Cassy M. and Svingen, Terje (2024). Perinatal exposure to environmental chemicals that disrupt thyroid function can perturb testis development. Environmental Pollution, 363 125117, 125117. doi: 10.1016/j.envpol.2024.125117

Perinatal exposure to environmental chemicals that disrupt thyroid function can perturb testis development

2024

Conference Publication

How the Australian Functional Genomics Network (AFGN) contributes to improved patient care

Scott, Hamish S., Matotek, Ebony, Mattiske, Tessa, Bryson-Richardson, Robert J., Smyth, Ian, Gecz, Jozef, Christodoulou, John, Palpant, Nathan, Smith, Kelly, Warr, Coral, Bennetts, Bruce, Thomas, Paul, Bowles, Josephine, Hilliard, Massimo, Hime, Gary, Hool, Livia, Quinn, Leonie, Wolvetang, Ernst, Jamieson, Robyn, Baynam, Gareth, Dudding-Byth, Tracy, Tan, Tiong Yang, Milnes, Di, Wallis, Mathew, Palmer, Elizabeth, Patel, Chirag, Jones, Kristi, Tam, Patrick, Stark, Zornitza ... Sinclair, Andrew (2024). How the Australian Functional Genomics Network (AFGN) contributes to improved patient care. Pathology Update 2024, Adelaide, SA, Australia, 1-3 March 2024. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2023.12.084

How the Australian Functional Genomics Network (AFGN) contributes to improved patient care

2024

Conference Publication

Variants in SART3 cause a novel spliceosomopathy characterised by failure of testis development and neuronal defects

Ayers, Katie, Eggers, Stefanie, Rollo, Ben, Smith, Katherine, Davidson, Nadia, Siddall, Nicole, Zhao, Liang, Bowles, Josephine, Weiss, Karin, Zanni, Ginevra, Burglen, Lydie, Ben Shachar, Shay, Rosensaft, Jenny, Raas-Rothschild, Annick, Jorgensen, Anne, Schittenhelm, Ralf, Huang, Cheng, Robevska, Gorjana, van den Bergen, Jocelyn, Casagranda, Franca, Cyza, Justyna, Pachernegg, Svenja, Wright, David, Bahlo, Melanie, Oshlack, Alicia, O'Brien, Terence, Kwan, Patrick, Koopman, Peter, Hime, Gary ... Sinclair, Andrew (2024). Variants in SART3 cause a novel spliceosomopathy characterised by failure of testis development and neuronal defects. 56th Annual Conference of the European Society of Human Genetics (ESHG), Glasgow, Scotland, 10-13 June 2023. London, United Kingdom: Nature Publishing Group.

Variants in SART3 cause a novel spliceosomopathy characterised by failure of testis development and neuronal defects

2023

Journal Article

Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects

Ayers, Katie L., Eggers, Stefanie, Rollo, Ben N., Smith, Katherine R., Davidson, Nadia M., Siddall, Nicole A., Zhao, Liang, Bowles, Josephine, Weiss, Karin, Zanni, Ginevra, Burglen, Lydie, Ben-Shachar, Shay, Rosensaft, Jenny, Raas-Rothschild, Annick, Jørgensen, Anne, Schittenhelm, Ralf B., Huang, Cheng, Robevska, Gorjana, van den Bergen, Jocelyn, Casagranda, Franca, Cyza, Justyna, Pachernegg, Svenja, Wright, David K., Bahlo, Melanie, Oshlack, Alicia, O’Brien, Terrence J., Kwan, Patrick, Koopman, Peter, Hime, Gary R. ... Sinclair, Andrew H. (2023). Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects. Nature Communications, 14 (1) 3403, 1-21. doi: 10.1038/s41467-023-39040-0

Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects

2023

Journal Article

Generation and characterization of a Ddx4‐iCre transgenic line for deletion in the germline beginning at genital ridge colonization

Burnet, Guillaume, Feng, Chun‐Wei Allen, Cheung, Ka Man Fiona, Bowles, Josephine and Spiller, Cassy M. (2023). Generation and characterization of a Ddx4‐iCre transgenic line for deletion in the germline beginning at genital ridge colonization. genesis, 61 (1-2) e23511, e23511. doi: 10.1002/dvg.23511

Generation and characterization of a Ddx4‐iCre transgenic line for deletion in the germline beginning at genital ridge colonization

2023

Book Chapter

Isolation and culture techniques for fetal mouse germ cells

Burnet, Guillaume, Bowles, Josephine and Spiller, Cassy M. (2023). Isolation and culture techniques for fetal mouse germ cells. Germline stem cells: methods and protocols. (pp. 221-231) edited by Michael Buszczak. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-3259-8_13

Isolation and culture techniques for fetal mouse germ cells

2022

Journal Article

Instructing mouse germ cells to adopt a female fate

Spiller, Cassy and Bowles, Josephine (2022). Instructing mouse germ cells to adopt a female fate. Sexual Development, 16 (5-6), 1-13. doi: 10.1159/000523763

Instructing mouse germ cells to adopt a female fate

2022

Journal Article

Deletion of NFIX results in defective progression through meiosis within the mouse testis

Davila, Raul Ayala, Spiller, Cassy, Harkins, Danyon, Harvey, Tracey, Jordan, Philip W., Gronostajski, Richard M., Piper, Michael and Bowles, Josephine (2022). Deletion of NFIX results in defective progression through meiosis within the mouse testis. Biology of Reproduction, 106 (6), 1191-1205. doi: 10.1093/biolre/ioac049

Deletion of NFIX results in defective progression through meiosis within the mouse testis

2022

Journal Article

Two ovarian candidate enhancers, identified by time series enhancer RNA analyses, harbor rare genetic variations identified in ovarian insufficiency

Nakagawa, Ryuichi, Takasawa, Kei, Gau, Maki, Tsuji-Hosokawa, Atsumi, Kawaji, Hideya, Murakawa, Yasuhiro, Takada, Shuji, Mikami, Masashi, Narumi, Satoshi, Fukami, Maki, Sreenivasan, Rajini, Maruyama, Tetsuo, Tucker, Elena J., Zhao, Liang, Bowles, Josephine, Sinclair, Andrew, Koopman, Peter, Hayashizaki, Yoshihide, Morio, Tomohiro and Kashimada, Kenichi (2022). Two ovarian candidate enhancers, identified by time series enhancer RNA analyses, harbor rare genetic variations identified in ovarian insufficiency. Human Molecular Genetics, 31 (13), 2223-2235. doi: 10.1093/hmg/ddac023

Two ovarian candidate enhancers, identified by time series enhancer RNA analyses, harbor rare genetic variations identified in ovarian insufficiency

2022

Journal Article

AOP Key Event Relationship report: Linking decreased retinoic acid levels with disrupted meiosis in developing oocytes

Kam Draskau, Monica, Ravn Ballegaard, Anne-Sofie, Ramhøj, Louise, Bowles, Josephine, Svingen, Terje and Spiller, Cassy M. (2022). AOP Key Event Relationship report: Linking decreased retinoic acid levels with disrupted meiosis in developing oocytes. Current Research in Toxicology, 3 100069, 1-8. doi: 10.1016/j.crtox.2022.100069

AOP Key Event Relationship report: Linking decreased retinoic acid levels with disrupted meiosis in developing oocytes

2021

Journal Article

WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis

Ho, Uda Y., Feng, Chun-Wei Allen, Yeap, Yvonne Y., Bain, Amanda L., Wei, Zhe, Shohayeb, Belal, Reichelt, Melissa E., Homer, Hayden, Khanna, Kum Kum, Bowles, Josephine and Ng, Dominic C. H. (2021). WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis. Communications Biology, 4 (1) 645, 1-14. doi: 10.1038/s42003-021-02171-5

WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis

2021

Journal Article

Identification of regulatory elements required for Stra8 expression, in fetal ovarian germ cells of the mouse

Feng, Chun-Wei, Burnet, Guillaume, Spiller, Cassy M., Cheung, Fiona Ka Man, Chawengsaksophak, Kallayanee, Koopman, Peter and Bowles, Josephine (2021). Identification of regulatory elements required for Stra8 expression, in fetal ovarian germ cells of the mouse. Development, 148 (5) dev194977, 1-13. doi: 10.1242/dev.194977

Identification of regulatory elements required for Stra8 expression, in fetal ovarian germ cells of the mouse

2020

Journal Article

CRIPTO and miR-371a-3p are serum biomarkers of testicular germ cell tumors and are detected in seminal plasma from azoospermic males

Spiller, Cassy M., Lobo, João, Boellaard, Willem P. A., Gillis, Ad J. M., Bowles, Josephine and Looijenga, Leendert H. J. (2020). CRIPTO and miR-371a-3p are serum biomarkers of testicular germ cell tumors and are detected in seminal plasma from azoospermic males. Cancers, 12 (3) 760, 760. doi: 10.3390/cancers12030760

CRIPTO and miR-371a-3p are serum biomarkers of testicular germ cell tumors and are detected in seminal plasma from azoospermic males

2020

Journal Article

Developmental biology meets toxicology: contributing reproductive mechanisms to build adverse outcome pathways

Draskau, Monica Kam, Spiller, Cassy M., Boberg, Julie, Bowles, Josephine and Svingen, Terje (2020). Developmental biology meets toxicology: contributing reproductive mechanisms to build adverse outcome pathways. Molecular Human Reproduction, 26 (2), 111-116. doi: 10.1093/molehr/gaaa001

Developmental biology meets toxicology: contributing reproductive mechanisms to build adverse outcome pathways

2019

Journal Article

A simple, web-based repository for the management, access and analysis of micrographic images

Davila, Raul Ayala, Harkins, Danyon, Currey, Laura, Fraser, James, Bowles, Josephine and Piper, Michael (2019). A simple, web-based repository for the management, access and analysis of micrographic images. Journal of Molecular Histology, 50 (6), 573-580. doi: 10.1007/s10735-019-09850-y

A simple, web-based repository for the management, access and analysis of micrographic images

2019

Journal Article

Author Correction: Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9

Croft, Brittany, Ohnesorg, Thomas, Hewitt, Jacqueline, Bowles, Josephine, Quinn, Alexander, Tan, Jacqueline, Corbin, Vincent, Pelosi, Emanuele, van den Bergen, Jocelyn, Sreenivasan, Rajini, Knarston, Ingrid, Robevska, Gorjana, Vu, Dung Chi, Hutson, John, Harley, Vincent, Ayers, Katie, Koopman, Peter and Sinclair, Andrew (2019). Author Correction: Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9. Nature Communications, 10 (1) 3351, 3351. doi: 10.1038/s41467-019-11310-w

Author Correction: Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9

2019

Journal Article

Nr5a1 suppression during the murine fetal period optimizes ovarian development by fine-tuning Notch signaling

Nomura, Risa, Kashimada, Kenichi, Suzuki, Hitomi, Zhao, Liang, Tsuji-Hosokawa, Atsumi, Yagita, Hideo, Takagi, Masatoshi, Kanai, Yoshiakira, Bowles, Josephine, Koopman, Peter, Kanai-Azuma, Masami and Morio, Tomohiro (2019). Nr5a1 suppression during the murine fetal period optimizes ovarian development by fine-tuning Notch signaling. Journal of Cell Science, 132 (8) 223768, jcs223768. doi: 10.1242/jcs.223768

Nr5a1 suppression during the murine fetal period optimizes ovarian development by fine-tuning Notch signaling

2019

Journal Article

Gene editing of the multi-copy H2A.B gene and its importance for fertility 06 Biological Sciences 0604 Genetics Jin-Soo Kim

Anuar, Nur Diana, Kurscheid, Sebastian, Field, Matt, Zhang, Lei, Rebar, Edward, Gregory, Philip, Buchou, Thierry, Bowles, Josephine, Koopman, Peter, Tremethick, David J. and Soboleva, Tatiana A. (2019). Gene editing of the multi-copy H2A.B gene and its importance for fertility 06 Biological Sciences 0604 Genetics Jin-Soo Kim. Genome Biology, 20 (1) 23, 23. doi: 10.1186/s13059-019-1633-3

Gene editing of the multi-copy H2A.B gene and its importance for fertility 06 Biological Sciences 0604 Genetics Jin-Soo Kim

2019

Book Chapter

Sexually dimorphic germ cell identity in mammals

Spiller, Cassy and Bowles, Josephine (2019). Sexually dimorphic germ cell identity in mammals. Sex determination in vertebrates. (pp. 253-288) Maryland Heights, MO, United States: Academic Press. doi: 10.1016/bs.ctdb.2019.01.011

Sexually dimorphic germ cell identity in mammals

2018

Journal Article

Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9

Croft, Brittany, Ohnesorg, Thomas, Hewitt, Jacky, Bowles, Josephine, Quinn, Alexander, Tan, Jacqueline, Corbin, Vincent, Pelosi, Emanuele, van den Bergen, Jocelyn, Sreenivasan, Rajini, Knarston, Ingrid, Robevska, Gorjana, Vu, Dung Chi, Hutson, John, Harley, Vincent, Ayers, Katie, Koopman, Peter and Sinclair, Andrew (2018). Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9. Nature Communications, 9 (1) 5319, 5319. doi: 10.1038/s41467-018-07784-9

Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9

Current funding

  • 2024 - 2025
    The foundations of a good egg: correctly transitioning from mitosis to meiosis
    Lalor Foundation, The
    Open grant
  • 2024 - 2027
    Foundations of a good egg: correctly transitioning from mitosis to meiosis
    ARC Discovery Projects
    Open grant
  • 2021 - 2026
    The Australian Functional Genomics Network (Administered by Murdoch Children's Research Institute)
    Murdoch Childrens Research Institute
    Open grant

Past funding

  • 2023 - 2024
    The Brain-Ovary connection: identification of a novel regulator of female reproductive function
    Repro Grants
    Open grant
  • 2021 - 2023
    Can inhalational general anaesthetic exposure during pregnancy affect non-genetic heritable elements in fetal germs cells in such a way as to engender pathology in offspring,
    Silicon Valley Community Foundation
    Open grant
  • 2020 - 2023
    How do mammalian germ cells transition from mitosis to meiosis?
    ARC Discovery Projects
    Open grant
  • 2019 - 2022
    Development of a non-invasive diagnostic and prognostic assay for adolescent testicular cancer
    The Kid's Cancer Project
    Open grant
  • 2018 - 2020
    Investigating spermatogonial stem cell allocation in the fetal testis
    ARC Discovery Projects
    Open grant
  • 2016 - 2018
    Exposing the mechanisms underlying mammalian meiotic onset
    NHMRC Project Grant
    Open grant
  • 2016 - 2019
    Molecular regulation of pluripotency in the mammalian germline
    NHMRC Project Grant
    Open grant
  • 2015 - 2016
    Nodal/Cripto signaling in germ cell development and tumorigenesis
    Cancer Council Queensland
    Open grant
  • 2014 - 2016
    Modelling stem cell decisions in mouse germ cells
    ARC Discovery Projects
    Open grant
  • 2012 - 2014
    Nodal signalling in male germ cell development: Balancing fertility and testicular cancer susceptibility
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    Molecular regulation of the mitosis-to-meiosis switch in germ cells
    ARC Discovery Projects
    Open grant
  • 2011 - 2012
    The Nodal/Cripto signalling pathway in male germ cell development: relevance to testicular germ cell tumours
    Cancer Council Queensland
    Open grant
  • 2003 - 2005
    Functional Analysis Of Candidate Sex-Determining And Gonadal Development In Genes
    NHMRC Project Grant
    Open grant
  • 2001
    Travel Grant to attend the 14th International Congress of Developmental Biology
    Potter Foundation
    Open grant
  • 2000 - 2002
    Molecular genetics of gonadal development
    NHMRC Project Grant
    Open grant
  • 1999
    Travel grant to attend the European Molecular Biology Laboratory Mouse Molecular Genetics Meeting, Heidelberg, Germany (September 1999)
    Potter Foundation
    Open grant
  • 1999
    Molecular genetics of gonadal development
    Mayne Bequest Fund
    Open grant
  • 1998 - 1999
    The smoothened gene in skin development and tumour formation
    Queensland Cancer Fund
    Open grant

Availability

Associate Professor Josephine Bowles is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Enquiries

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