Professor Josephine Bowles
Professor

Josephine Bowles

Email: 
Phone: 
+61 7 336 53056

Availability

Professor Josephine Bowles is:
Available for supervision

Fields of research

Biological Sciences Genetics

Qualifications

  • Bachelor (Honours) of Science (Advanced), The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Search Professor Josephine Bowles’s works on UQ eSpace

120 works between 1991 and 2025
All (120) Journal Article (99) Book Chapter (6) Conference Publication (15)

21 - 40 of 120 works

2018

Journal Article

Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9

Croft, Brittany, Ohnesorg, Thomas, Hewitt, Jacky, Bowles, Josephine, Quinn, Alexander, Tan, Jacqueline, Corbin, Vincent, Pelosi, Emanuele, van den Bergen, Jocelyn, Sreenivasan, Rajini, Knarston, Ingrid, Robevska, Gorjana, Vu, Dung Chi, Hutson, John, Harley, Vincent, Ayers, Katie, Koopman, Peter and Sinclair, Andrew (2018). Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9. Nature Communications, 9 (1) 5319, 5319. doi: 10.1038/s41467-018-07784-9

Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9

2018

Journal Article

Retinoic acid antagonizes testis development in mice

Bowles, Josephine, Feng, Chun-Wei, Ineson, Jessica, Miles, Kim, Spiller, Cassy M., Harley, Vincent R., Sinclair, Andrew H. and Koopman, Peter (2018). Retinoic acid antagonizes testis development in mice. Cell Reports, 24 (5), 1330-1341. doi: 10.1016/j.celrep.2018.06.111

Retinoic acid antagonizes testis development in mice

2018

Journal Article

Prolonged prenatal hypoxia selectively disrupts collecting duct patterning and postnatal function in male mouse offspring

Walton, Sarah L., Singh, Reetu R., Little, Melissa H., Bowles, Josephine, Li, Joan and Moritz, Karen M. (2018). Prolonged prenatal hypoxia selectively disrupts collecting duct patterning and postnatal function in male mouse offspring. The Journal of Physiology, 596 (23), 5873-5889. doi: 10.1113/JP275918

Prolonged prenatal hypoxia selectively disrupts collecting duct patterning and postnatal function in male mouse offspring

2018

Journal Article

Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling

Sinha, Debottam, Kalimutho, Murugan, Bowles, Josephine, Chan, Ai-Leen, Merriner, D. Jo, Bain, Amanda L., Simmons, Jacinta L., Freire, Raimundo, Lopez, J Alejandro, Hobbs, Robin M., O'Bryan, Moira K. and Khanna, Kum Kum (2018). Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling. The FASEB Journal, 32 (9), 4984-4999. doi: 10.1096/fj.201701096RR

Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling

2018

Conference Publication

Gene editing of the multi-copy H2A.B gene family by a single pair of TALENs in mice

Anuar, Nur Diana, Field, Matt, Kurscheid, Sebastian, Zhang, Lei, Rebar, Edward, Gregory, Philip, Bowles, Josephine, Koopman, Peter, Tremethick, David J. and Soboleva, Tatiana (2018). Gene editing of the multi-copy H2A.B gene family by a single pair of TALENs in mice. LONDON: BIOMED CENTRAL LTD.

Gene editing of the multi-copy H2A.B gene family by a single pair of TALENs in mice

2017

Journal Article

SOX30 is required for male fertility in mice

Feng, Chun-Wei Allen, Spiller, Cassy, Merriner, Donna J., O'Bryan, Moira K., Bowles, Josephine and Koopman, Peter (2017). SOX30 is required for male fertility in mice. Scientific Reports, 7 (1) 17619, 1-12. doi: 10.1038/s41598-017-17854-5

SOX30 is required for male fertility in mice

2017

Journal Article

Sex Determination in the Mammalian Germline

Spiller, Cassy, Koopman, Peter and Bowles, Josephine (2017). Sex Determination in the Mammalian Germline. Annual Review of Genetics, 51 (1), 265-285. doi: 10.1146/annurev-genet-120215-035449

Sex Determination in the Mammalian Germline

2017

Journal Article

Regulation of fetal male germ cell development by members of the TGFβ superfamily

Spiller, Cassy, Burnet, Guillaume and Bowles, Josephine (2017). Regulation of fetal male germ cell development by members of the TGFβ superfamily. Stem cell research, 24, 174-180. doi: 10.1016/j.scr.2017.07.016

Regulation of fetal male germ cell development by members of the TGFβ superfamily

2017

Journal Article

Germ cell neoplasia in situ: the precursor cell for invasive germ cell tumors of the testis

Spiller, Cassy M. and Bowles, Josephine (2017). Germ cell neoplasia in situ: the precursor cell for invasive germ cell tumors of the testis. International Journal of Biochemistry & Cell Biology, 86, 22-25. doi: 10.1016/j.bioce1.2017.03.004

Germ cell neoplasia in situ: the precursor cell for invasive germ cell tumors of the testis

2017

Journal Article

Mice lacking Hbp1 function are viable and fertile

Spiller, Cassy M., Wilhelm, Dagmar, Jans, David A., Bowles, Josephine and Koopman, Peter (2017). Mice lacking Hbp1 function are viable and fertile. PLoS One, 12 (1) e0170576, e0170576. doi: 10.1371/journal.pone.0170576

Mice lacking Hbp1 function are viable and fertile

2017

Book Chapter

Mouse fetal germ cell isolation and culture techniques

Spiller, Cassy M., Burnet, Guillaume and Bowles, Josephine (2017). Mouse fetal germ cell isolation and culture techniques. Germline stem cells. (pp. 173-183) edited by Michael Buszczak. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-4017-2_13

Mouse fetal germ cell isolation and culture techniques

2016

Journal Article

Cripto: expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors

Spiller, Cassy M., Gillis, Ad J. M., Burnet, Guillaume, Stoop, Hans, Koopman, Peter, Bowles, Josephine and Looijenga, Leendert H. J. (2016). Cripto: expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors. Molecular Oncology, 10 (4), 526-537. doi: 10.1016/j.molonc.2015.11.003

Cripto: expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors

2016

Journal Article

Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility

Holm, Jacob Bak, Mazaud-Guittot, Severine, Danneskiold-Samsoe, Niels Banhos, Chalmey, Clementine, Jensen, Benjamin, Norregard, Mette Marie, Hansen, Cecilie Hurup, Styrishave, Bjarne, Svingen, Terje, Vinggaard, Anne Marie, Koch, Holger Martin, Bowles, Josephine, Koopman, Peter, Jegou, Bernard, Kristiansen, Karsten and Kristensen, David Mobjerg (2016). Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility. Toxicological Sciences, 150 (1), 178-189. doi: 10.1093/toxsci/kfv332

Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility

2016

Journal Article

ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries

Bowles, Josephine, Feng, Chun-Wei, Miles, Kim, Ineson, Jessica, Spiller, Cassy and Koopman, Peter (2016). ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries. Nature Communications, 7 (1) 10845, 10845.1-10845.8. doi: 10.1038/ncomms10845

ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries

2016

Journal Article

Culturing murine embryonic organs: pros, cons, tips and tricks

McClelland, Kathryn S. and Bowles, Josephine (2016). Culturing murine embryonic organs: pros, cons, tips and tricks. Differentiation, 91 (4-5), 50-56. doi: 10.1016/j.diff.2016.01.008

Culturing murine embryonic organs: pros, cons, tips and tricks

2016

Journal Article

Germ cells influence cord formation and leydig cell gene expression during mouse testis development

Rios-Rojas, Clarissa, Spiller, Cassy, Bowles, Josephine and Koopman, Peter (2016). Germ cells influence cord formation and leydig cell gene expression during mouse testis development. Developmental Dynamics, 245 (4), 433-444. doi: 10.1002/dvdy.24371

Germ cells influence cord formation and leydig cell gene expression during mouse testis development

2015

Journal Article

Agarose/gelatin immobilisation of tissues or embryo segments for orientated paraffin embedding and sectioning

McClelland, Kathryn S., Ng, Ee Ting and Bowles, Josephine (2015). Agarose/gelatin immobilisation of tissues or embryo segments for orientated paraffin embedding and sectioning. Differentiation, 91 (4-5), 68-71. doi: 10.1016/j.diff.2015.12.001

Agarose/gelatin immobilisation of tissues or embryo segments for orientated paraffin embedding and sectioning

2015

Journal Article

Purification and Transcriptomic analysis of mouse fetal leydig cells reveals candidate genes for specification of gonadal steroidogenic cells

McClelland, Kathryn S., Bell, Katrina, Larney, Christian, Harley, Vincent R., Sinclair, Andrew H., Oshlack, Alicia, Koopman, Peter A. and Bowles, Josephine (2015). Purification and Transcriptomic analysis of mouse fetal leydig cells reveals candidate genes for specification of gonadal steroidogenic cells. Biology of Reproduction, 92 (6), 145-145. doi: 10.1095/biolreprod.115.128918

Purification and Transcriptomic analysis of mouse fetal leydig cells reveals candidate genes for specification of gonadal steroidogenic cells

2015

Journal Article

Sex determination in mammalian germ cells

Spiller, Cassy M. and Bowles, Josephine (2015). Sex determination in mammalian germ cells. Asian Journal of Andrology, 17 (3), 427-432. doi: 10.4103/1008-682X.150037

Sex determination in mammalian germ cells

2015

Journal Article

On the role of germ cells in mammalian gonad development: quiet passengers or back-seat drivers?

Rios-Rojas, Clarissa, Bowles, Josephine and Koopman, Peter (2015). On the role of germ cells in mammalian gonad development: quiet passengers or back-seat drivers?. Reproduction, 149 (4), R181-R191. doi: 10.1530/REP-14-0663

On the role of germ cells in mammalian gonad development: quiet passengers or back-seat drivers?

Current funding

  • 2024 - 2025
    The foundations of a good egg: correctly transitioning from mitosis to meiosis
    Lalor Foundation, The
    Open grant
  • 2024 - 2027
    Foundations of a good egg: correctly transitioning from mitosis to meiosis
    ARC Discovery Projects
    Open grant

Past funding

  • 2023 - 2024
    The Brain-Ovary connection: identification of a novel regulator of female reproductive function
    Repro Grants
    Open grant
  • 2021 - 2023
    Can inhalational general anaesthetic exposure during pregnancy affect non-genetic heritable elements in fetal germs cells in such a way as to engender pathology in offspring,
    Silicon Valley Community Foundation
    Open grant
  • 2021 - 2024
    The Australian Functional Genomics Network (Administered by Murdoch Children's Research Institute)
    Murdoch Childrens Research Institute
    Open grant
  • 2020 - 2023
    How do mammalian germ cells transition from mitosis to meiosis?
    ARC Discovery Projects
    Open grant
  • 2019 - 2022
    Development of a non-invasive diagnostic and prognostic assay for adolescent testicular cancer
    The Kid's Cancer Project
    Open grant
  • 2018 - 2020
    Investigating spermatogonial stem cell allocation in the fetal testis
    ARC Discovery Projects
    Open grant
  • 2016 - 2018
    Exposing the mechanisms underlying mammalian meiotic onset
    NHMRC Project Grant
    Open grant
  • 2016 - 2019
    Molecular regulation of pluripotency in the mammalian germline
    NHMRC Project Grant
    Open grant
  • 2015 - 2016
    Nodal/Cripto signaling in germ cell development and tumorigenesis
    Cancer Council Queensland
    Open grant
  • 2014 - 2016
    Modelling stem cell decisions in mouse germ cells
    ARC Discovery Projects
    Open grant
  • 2012 - 2014
    Nodal signalling in male germ cell development: Balancing fertility and testicular cancer susceptibility
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    Molecular regulation of the mitosis-to-meiosis switch in germ cells
    ARC Discovery Projects
    Open grant
  • 2011 - 2012
    The Nodal/Cripto signalling pathway in male germ cell development: relevance to testicular germ cell tumours
    Cancer Council Queensland
    Open grant
  • 2003 - 2005
    Functional Analysis Of Candidate Sex-Determining And Gonadal Development In Genes
    NHMRC Project Grant
    Open grant
  • 2001
    Travel Grant to attend the 14th International Congress of Developmental Biology
    Potter Foundation
    Open grant
  • 2000 - 2002
    Molecular genetics of gonadal development
    NHMRC Project Grant
    Open grant
  • 1999
    Travel grant to attend the European Molecular Biology Laboratory Mouse Molecular Genetics Meeting, Heidelberg, Germany (September 1999)
    Potter Foundation
    Open grant
  • 1999
    Molecular genetics of gonadal development
    Mayne Bequest Fund
    Open grant
  • 1998 - 1999
    The smoothened gene in skin development and tumour formation
    Queensland Cancer Fund
    Open grant

Availability

Professor Josephine Bowles is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

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