Professor Jessica Mar
Professor

Jessica Mar

Email: 

Availability

Professor Jessica Mar is:
Available for supervision

Fields of research

Bioinformatics and computational biology Biological Sciences

Qualifications

  • Doctor of Philosophy, Harvard University

Search Professor Jessica Mar’s works on UQ eSpace

76 works between 2003 and 2024
All (76) Journal Article (73) Conference Publication (3)

1 - 20 of 76 works

2024

Journal Article

Superior induced pluripotent stem cell generation through Phactr-3-driven mechano-modulation of both early and late phases of cell reprogramming

Chowdhury, Mohammad Mahfuz, Zimmerman, Samuel, Leeson, Hannah, Nefzger, Christian Maximilian, Mar, Jessica Cara, Laslett, Andrew, Polo, Jose Maria, Wolvetang, Ernst and Cooper-White, Justin (2024). Superior induced pluripotent stem cell generation through Phactr-3-driven mechano-modulation of both early and late phases of cell reprogramming. Biomaterials Research, 28 0025, 0025. doi: 10.34133/bmr.0025

Superior induced pluripotent stem cell generation through Phactr-3-driven mechano-modulation of both early and late phases of cell reprogramming

2024

Journal Article

Redox signalling regulates breast cancer metastasis via phenotypic and metabolic reprogramming due to p63 activation by HIF1α

Ren, Zuen, Dharmaratne, Malindrie, Liang, Huizhi, Benard, Outhiriaradjou, Morales-Gallego, Miriam, Suyama, Kimita, Kumar, Viney, Fard, Atefeh Taherian, Kulkarni, Ameya S., Prystowsky, Michael, Mar, Jessica C., Norton, Larry and Hazan, Rachel B. (2024). Redox signalling regulates breast cancer metastasis via phenotypic and metabolic reprogramming due to p63 activation by HIF1α. British Journal of Cancer, 130 (6), 908-924. doi: 10.1038/s41416-023-02522-5

Redox signalling regulates breast cancer metastasis via phenotypic and metabolic reprogramming due to p63 activation by HIF1α

2023

Journal Article

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Aguado, Julio, Amarilla, Alberto A., Taherian Fard, Atefeh, Albornoz, Eduardo A., Tyshkovskiy, Alexander, Schwabenland, Marius, Chaggar, Harman K., Modhiran, Naphak, Gómez-Inclán, Cecilia, Javed, Ibrahim, Baradar, Alireza A., Liang, Benjamin, Peng, Lianli, Dharmaratne, Malindrie, Pietrogrande, Giovanni, Padmanabhan, Pranesh, Freney, Morgan E., Parry, Rhys, Sng, Julian D. J., Isaacs, Ariel, Khromykh, Alexander A., Valenzuela Nieto, Guillermo, Rojas-Fernandez, Alejandro, Davis, Thomas P., Prinz, Marco, Bengsch, Bertram, Gladyshev, Vadim N., Woodruff, Trent M., Mar, Jessica C. ... Wolvetang, Ernst J. (2023). Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology. Nature Aging, 3 (12), 1561-1575. doi: 10.1038/s43587-023-00519-6

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

2023

Journal Article

Measuring cell-to-cell expression variability in single-cell RNA-sequencing data: a comparative analysis and applications to B cell aging

Zheng, Huiwen, Vijg, Jan, Fard, Atefeh Taherian and Mar, Jessica Cara (2023). Measuring cell-to-cell expression variability in single-cell RNA-sequencing data: a comparative analysis and applications to B cell aging. Genome Biology, 24 (1) 238, 1-26. doi: 10.1186/s13059-023-03036-2

Measuring cell-to-cell expression variability in single-cell RNA-sequencing data: a comparative analysis and applications to B cell aging

2023

Journal Article

Deconstructing heterogeneity of replicative senescence in human mesenchymal stem cells at single cell resolution

Taherian Fard, Atefeh, Leeson, Hannah C., Aguado, Julio, Pietrogrande, Giovanni, Power, Dominique, Gómez-Inclán, Cecilia, Zheng, Huiwen, Nelson, Christopher B., Soheilmoghaddam, Farhad, Glass, Nick, Dharmaratne, Malindrie, Watson, Ebony R., Lu, Jennifer, Martin, Sally, Pickett, Hilda A., Cooper-White, Justin, Wolvetang, Ernst J. and Mar, Jessica C. (2023). Deconstructing heterogeneity of replicative senescence in human mesenchymal stem cells at single cell resolution. GeroScience, 46 (1), 1-17. doi: 10.1007/s11357-023-00829-y

Deconstructing heterogeneity of replicative senescence in human mesenchymal stem cells at single cell resolution

2023

Journal Article

scShapes: a statistical framework for identifying distribution shapes in single-cell RNA-sequencing data

Dharmaratne, Malindrie, Kulkarni, Ameya S., Taherian Fard, Atefeh and Mar, Jessica C. (2023). scShapes: a statistical framework for identifying distribution shapes in single-cell RNA-sequencing data. GigaScience, 12 giac126, 1-18. doi: 10.1093/gigascience/giac126

scShapes: a statistical framework for identifying distribution shapes in single-cell RNA-sequencing data

2022

Journal Article

Biophysical Reviews special issue call: quantitative methods to decipher cellular heterogeneity — from single-cell to spatial omic methods

Ho, Joshua W. K., Chen, Xi, He, Mu, Huang, Yuanhua, Mar, Jessica C., Shih, David J. H. and Wu, Angela R. (2022). Biophysical Reviews special issue call: quantitative methods to decipher cellular heterogeneity — from single-cell to spatial omic methods. Biophysical Reviews, 14 (5), 1079-1080. doi: 10.1007/s12551-022-00994-y

Biophysical Reviews special issue call: quantitative methods to decipher cellular heterogeneity — from single-cell to spatial omic methods

2022

Journal Article

How does the structure of data impact cell–cell similarity? Evaluating how structural properties influence the performance of proximity metrics in single cell RNA-seq data

Watson, Ebony Rose, Mora, Ariane, Taherian Fard, Atefeh and Mar, Jessica Cara (2022). How does the structure of data impact cell–cell similarity? Evaluating how structural properties influence the performance of proximity metrics in single cell RNA-seq data. Briefings in Bioinformatics, 23 (6) bbac387, 1-14. doi: 10.1093/bib/bbac387

How does the structure of data impact cell–cell similarity? Evaluating how structural properties influence the performance of proximity metrics in single cell RNA-seq data

2022

Journal Article

Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease

Ding, Qiao, Kesavan, Kaamini, Lee, Kah Meng, Wimberger, Elyse, Robertson, Thomas, Gill, Melinder, Power, Dominique, Chang, Jeryn, Fard, Atefeh T., Mar, Jessica C., Henderson, Robert D., Heggie, Susan, McCombe, Pamela A., Jeffree, Rosalind L., Colditz, Michael J., Hilliard, Massimo A., Ng, Dominic C. H., Steyn, Frederik J., Phillips, William D., Wolvetang, Ernst J., Ngo, Shyuan T. and Noakes, Peter G. (2022). Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease. Acta Neuropathologica Communications, 10 (1) 61, 61. doi: 10.1186/s40478-022-01360-5

Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease

2022

Conference Publication

Softer, faster, better! - Substrate mechanics drives superior somatic cell reprogramming outcomes

Cooper-White, Justin, Chowdhury, Mahfuz, Wolvetang, Ernst, Zimmerman, Samuel, Mar, Jessica, Polo, Jose, Laslett, Andrew and Nefzger, Christian (2022). Softer, faster, better! - Substrate mechanics drives superior somatic cell reprogramming outcomes. TERMIS 6th World Congress, Maastricht, Netherlands, 15-19 November 2021. New Rochelle, NY United States: Mary Ann Liebert.

Softer, faster, better! - Substrate mechanics drives superior somatic cell reprogramming outcomes

2022

Journal Article

Redox signaling by glutathione peroxidase 2 links vascular modulation to metabolic plasticity of breast cancer

Ren, Zuen, Liang, Huizhi, Galbo, Phillip M., Dharmaratne, Malindrie, Kulkarni, Ameya S., Fard, Atefeh Taherian, Aoun, Marie Louise, Martinez-Lopez, Nuria, Suyama, Kimita, Benard, Outhiriaradjou, Zheng, Wei, Liu, Yang, Albanese, Joseph, Zheng, Deyou, Mar, Jessica C., Singh, Rajat, Prystowsky, Michael B., Norton, Larry and Hazan, Rachel B. (2022). Redox signaling by glutathione peroxidase 2 links vascular modulation to metabolic plasticity of breast cancer. Proceedings of the National Academy of Sciences, 119 (8) e2107266119. doi: 10.1073/pnas.2107266119

Redox signaling by glutathione peroxidase 2 links vascular modulation to metabolic plasticity of breast cancer

2022

Journal Article

Computational methods for single-cell imaging and omics data integration

Watson, Ebony Rose, Taherian Fard, Atefeh and Mar, Jessica Cara (2022). Computational methods for single-cell imaging and omics data integration. Frontiers in Molecular Biosciences, 8 768106, 768106. doi: 10.3389/fmolb.2021.768106

Computational methods for single-cell imaging and omics data integration

2021

Journal Article

Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Grapotte, Mathys, Saraswat, Manu, Bessière, Chloé, Menichelli, Christophe, Ramilowski, Jordan A., Severin, Jessica, Hayashizaki, Yoshihide, Itoh, Masayoshi, Tagami, Michihira, Murata, Mitsuyoshi, Kojima-Ishiyama, Miki, Noma, Shohei, Noguchi, Shuhei, Kasukawa, Takeya, Hasegawa, Akira, Suzuki, Harukazu, Nishiyori-Sueki, Hiromi, Frith, Martin C., Abugessaisa, Imad, Aitken, Stuart, Aken, Bronwen L., Alam, Intikhab, Alam, Tanvir, Alasiri, Rami, Alhendi, Ahmad M. N., Alinejad-Rokny, Hamid, Alvarez, Mariano J., Andersson, Robin, Arakawa, Takahiro ... Lecellier, Charles-Henri (2021). Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network. Nature Communications, 12 (1) 3297. doi: 10.1038/s41467-021-23143-7

Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

2020

Journal Article

The shape of gene expression distributions matter: how incorporating distribution shape improves the interpretation of cancer transcriptomic data

de Torrente, Laurence, Zimmerman, Samuel, Suzuki, Masako, Christopeit, Maximilian, Greally, John M. and Mar, Jessica C. (2020). The shape of gene expression distributions matter: how incorporating distribution shape improves the interpretation of cancer transcriptomic data. BMC Bioinformatics, 21 (Suppl 21) 562, 562. doi: 10.1186/s12859-020-03892-w

The shape of gene expression distributions matter: how incorporating distribution shape improves the interpretation of cancer transcriptomic data

2020

Journal Article

Investigating transcriptome-wide sex dimorphism by multi-level analysis of single-cell RNA sequencing data in ten mouse cell types

Lu, Tianyuan and Mar, Jessica C. (2020). Investigating transcriptome-wide sex dimorphism by multi-level analysis of single-cell RNA sequencing data in ten mouse cell types. Biology of Sex Differences, 11 (1) 61, 61. doi: 10.1186/s13293-020-00335-2

Investigating transcriptome-wide sex dimorphism by multi-level analysis of single-cell RNA sequencing data in ten mouse cell types

2020

Journal Article

Single-cell analysis of transcriptome and DNA methylome in human oocyte maturation

Yu, Bo, Doni Jayavelu, Naresh, Battle, Stephanie L., Mar, Jessica C., Schimmel, Timothy, Cohen, Jacques and Hawkins, R. David (2020). Single-cell analysis of transcriptome and DNA methylome in human oocyte maturation. PLoS One, 15 (11) e0241698, e0241698. doi: 10.1371/journal.pone.0241698

Single-cell analysis of transcriptome and DNA methylome in human oocyte maturation

2020

Journal Article

Metformin alters skeletal muscle transcriptome adaptations to resistance training in older adults

Kulkarni, Ameya S., Peck, Bailey D., Walton, R. Grace, Kern, Philip A., Mar, Jessica C., Windham, Samuel T., Bamman, Marcas M., Barzilai, Nir and Peterson, Charlotte A. (2020). Metformin alters skeletal muscle transcriptome adaptations to resistance training in older adults. Aging, 12 (20), 19852-19866. doi: 10.18632/aging.104096

Metformin alters skeletal muscle transcriptome adaptations to resistance training in older adults

2020

Journal Article

Identification of a novel subgroup of endometrial cancer patients with loss of thyroid hormone receptor beta expression and improved survival

Piqué, Daniel G., Greally, John M. and Mar, Jessica C. (2020). Identification of a novel subgroup of endometrial cancer patients with loss of thyroid hormone receptor beta expression and improved survival. BMC Cancer, 20 (1) 857, 857. doi: 10.1186/s12885-020-07325-y

Identification of a novel subgroup of endometrial cancer patients with loss of thyroid hormone receptor beta expression and improved survival

2020

Conference Publication

Redox regulation of tumor cell heterogeneity in the PyMT mammary tumor model revealed by single cell RNA sequencing

Ren, Zuen, Dharmaratne, Malindrie, Kulkarni, Ameya, Fard, Atefeh Taherian, Mar, Jessica, Galbo, Phillip M., Liu, Yang, Zheng, Deyou, Liang, Huizhi, Benard, Outhiriaradjou, Suyama, Kimita, Prystowsky, Michael B., Norton, Larry and Hazan, Rachel B. (2020). Redox regulation of tumor cell heterogeneity in the PyMT mammary tumor model revealed by single cell RNA sequencing. AACR Annual Meeting, Online, 22-24 June, 2020. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2020-4426

Redox regulation of tumor cell heterogeneity in the PyMT mammary tumor model revealed by single cell RNA sequencing

2020

Journal Article

Protein-protein interactions uncover candidate 'core genes' within omnigenic disease networks

Ratnakumar, Abhirami, Weinhold, Nils, Mar, Jessica C. and Riaz, Nadeem (2020). Protein-protein interactions uncover candidate 'core genes' within omnigenic disease networks. PLoS Genetics, 16 (7) e1008903, e1008903. doi: 10.1371/journal.pgen.1008903

Protein-protein interactions uncover candidate 'core genes' within omnigenic disease networks

Current funding

  • 2023 - 2025
    A human brain organoid model of acute prenatal hypoxia enables biomarker discovery and drug screening for hypoxic-ischemic encephalopathy.
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2021 - 2022
    UQ AWARE - A/Prof Jessica Mar
    UQ Amplify Women's Academic Research Equity
    Open grant
  • 2020 - 2023
    Noise rules: investigating how heterogeneity impacts disease transcriptomes
    Georgina Sweet Award for Women in Quantitative Biomedical Science
    Open grant
  • 2018 - 2023
    Developing bioinformatics methods for single cell transcriptomics.
    ARC Future Fellowships
    Open grant
  • 2018 - 2021
    Defective repair of neuronal activity-induced DNA double strand breaks: A novel pathogenic mechanism for neurodegeneration in ataxia-telangiectasia
    NHMRC Project Grant
    Open grant
  • 2011 - 2019
    Stem Cells Australia (ARC Special Research Initiative administered by the University of Melbourne)
    University of Melbourne
    Open grant

Availability

Professor Jessica Mar is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

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