Giovanni Pietrogrande

Development of a new CRISPR-Cas9 platform for safe gene editing

Development of a new CRISPR-Cas9 platform for safe gene editing

We are at the forefront of developing and validating an innovative technology that aims to make gene editing both safer and more cost-effective. This cutting-edge approach has the potential to revolutionize not only medical research and treatments but also industrial applications. By leveraging this breakthrough, we hope to open new doors in personalized medicine, synthetic biology, and beyond.

If you are passionate about transformative science and wish to contribute to this exciting endeavor, we would love to have you join our team. Whether you’re interested in experimental research, computational analysis, or technology development, there are plenty of ways to get involved!

Pioneering an Immunocompetent, Myelinated Brain Organoid model for studying neuroinflammation and diseases

We are the only group worldwide that has developed a groundbreaking brain organoid model that integrates myelinated axons and immune cells (microglia) within the same system. This unique model offers unprecedented opportunities to study complex neurological and immunological interactions. While we are currently leveraging this model to explore the mechanisms underlying multiple sclerosis, its potential applications extend far beyond, opening avenues to investigate a wide range of diseases.

We are seeking passionate and curious students to join our team and contribute to this transformative research. This project sits at the exciting intersection of stem cell biology, brain organoids, immunology, virology, and synthetic biology. Together, we aim to tackle critical health challenges and develop innovative approaches to understanding and treating diseases that significantly impact people’s lives.

If you are ready to make a difference through cutting-edge science, we would love to have you on board!

Creating a Novel Brain Organoid Model for Personalized Medicine

Our team is recognized as a leader in brain organoid technology, both in Australia and internationally. We are committed to pushing the boundaries of what’s possible, and we are now at the forefront of developing a groundbreaking organoid model using patient-derived cells to give them a personalized immune system. While our current focus is on Parkinson’s disease, this approach aims to evolve into a versatile platform for high-throughput drug screening, catering to the needs of pharmaceutical companies and hospitals while expanding to address other critical conditions in the future.

This interdisciplinary project, in collaboration with the School of Biomedical Sciences and other expert partners, provides an exceptional opportunity for students to acquire cutting-edge skills and expertise. You will gain hands-on experience in immunology, stem cell technology, and advanced organoid modeling, all while contributing to research that could revolutionize patient care and truly make a difference in people’s lives.

If you are excited by the idea of working at the intersection of innovation and impact, join us in shaping the future of personalized medicine!