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Professor Thomas Burne
Professor

Thomas Burne

Email: 

Overview

Background

Professor Burne is a leading Australian researcher in the field of biological psychiatry. Prof. Burne has >150 peer reviewed publications, which have attracted over 8500 citations (H-index 50). His research impact is evident by his 11 papers with >200 citations, with two recognised as Web of Science ‘Highly Cited Papers’. Together with collaborators he has been awarded >$8 million in research funding. Since 2003 he has supervised 17 PhD students, and 28 honours students Prof. Burne has a broad background in behavioural neuroscience, with specific training and expertise in animal models. As a Professorial Research Fellow with the Queensland Centre for Mental Health Research and Group Leader at the Queensland Brain Institute (QBI) the focus of his research includes cognitive testing in rodent models of neuropsychiatric disorders, such as schizophrenia, as well as psychopharmacological studies and research on clinical populations. As a CI on several university- and NHMRC-funded grants, he has helped establish infrastructure at QBI for behavioural assessment and methods of automated operant-based cognitive tests in rodents. Prof. Burne is a past president of Biological Psychiatry Australia, he is the Queensland representative for the Australasian Neuroscience Society, and he is a member of the NHMRC Animal Welfare Committee.

Prof. Burne’s group studies brain development and behaviour in animal models to learn more about neuropsychiatric diseases, such as schizophrenia. Research is focused on investigating the underlying biological basis for schizophrenia, with the goal of finding public health interventions that will alleviate the burden of this disease. The group has been exploring the impact of developmental vitamin D (DVD) deficiency on brain development, the impact of adult vitamin D deficiency on brain function and behaviour, and the neurobiological affects of having an older father. More recently his group has been focussed on assessing cognitive function in rodents. Prof. Burne’s research is carried out in close collaboration with Professors John McGrath and Darryl Eyles, in a multidisciplinary team. Together they have an integrated research program using a broad range of neuroscientific techniques to explore potential causes of schizophrenia. There is a particular focus on early life, nongenetic risk factors and the team has skills in epidemiology, psychiatry, neuroanatomy, molecular biology, developmental biology and behavioural neuroscience. The Burne group is currently developing animal models related to risk factors for schizophrenia and autism.

Availability

Professor Thomas Burne is:
Available for supervision
Media expert

Fields of research

Works

Search Professor Thomas Burne’s works on UQ eSpace

222 works between 1996 and 2024

1 - 20 of 222 works

Featured

2013

Journal Article

Cognitive performance and response inhibition in developmentally vitamin D (DVD)-deficient rats

Turner, Karly M., Young, Jared W., McGrath, John J., Eyles, Darryl W. and Burne, Thomas H. J. (2013). Cognitive performance and response inhibition in developmentally vitamin D (DVD)-deficient rats. Behavioural Brain Research, 242 (1), 47-53. doi: 10.1016/j.bbr.2012.12.029

Cognitive performance and response inhibition in developmentally vitamin D (DVD)-deficient rats

Featured

2013

Journal Article

Adult vitamin D deficiency leads to behavioural and brain neurochemical alterations in C57BL/6J and BALB/c mice

Groves, Natalie J., Kesby, James P., Eyles, Darryl W., McGrath, John J., Mackay-Sim, Alan and Burne, Thomas H. J. (2013). Adult vitamin D deficiency leads to behavioural and brain neurochemical alterations in C57BL/6J and BALB/c mice. Behavioural Brain Research, 241 (1), 120-131. doi: 10.1016/j.bbr.2012.12.001

Adult vitamin D deficiency leads to behavioural and brain neurochemical alterations in C57BL/6J and BALB/c mice

Featured

2013

Journal Article

Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease

Eyles, Darryl, Burne, Thomas H. J. and McGrath, John J. (2013). Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease. Frontiers in Neuroendocrinology, 34 (1), 47-64. doi: 10.1016/j.yfrne.2012.07.001

Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease

Featured

2011

Journal Article

Increased de novo copy number variants in the offspring of older males

Flatscher-Bader, T., Foldi, C. J., Chong, S., Whitelaw, E., Moser, R. J., Burne, T. H. J., Eyles, D. W. and McGrath, J. J. (2011). Increased de novo copy number variants in the offspring of older males. Translational Psychiatry, 1 (Article # e34) e34, e34-e34. doi: 10.1038/tp.2011.30

Increased de novo copy number variants in the offspring of older males

Featured

2011

Journal Article

Big ideas for small brains: What can psychiatry learn from worms, flies, bees and fish?

Burne, T. H. J., Scott, E., van Swinderen, B., Hilliard, M., Reinhard, J., Claudianos, C., Eyles, D. W. and McGrath, J. J. (2011). Big ideas for small brains: What can psychiatry learn from worms, flies, bees and fish?. Molecular Psychiatry, 16 (1), 7-16. doi: 10.1038/mp.2010.35

Big ideas for small brains: What can psychiatry learn from worms, flies, bees and fish?

Featured

2010

Journal Article

Developmental vitamin D deficiency and risk of schizophrenia: A 10-year update

McGrath, John J., Burne, Thomas H., Feron, Francois, Mackay-Sim, Allan and Eyles, Darryl W. (2010). Developmental vitamin D deficiency and risk of schizophrenia: A 10-year update. Schizophrenia Bulletin, 36 (6), 1073-1078. doi: 10.1093/schbul/sbq101

Developmental vitamin D deficiency and risk of schizophrenia: A 10-year update

Featured

2010

Journal Article

Neonatal vitamin D status and risk of schizophrenia: A population-based case-control study

McGrath, John J., Eyles, Darryl W., Pedersen, Carsten B., Anderson, Cameron, Ko, Pauline, Burne, Thomas H., Norgaard-Pedersen, Bent, Hougaard, David M. and Mortensen, Preben B. (2010). Neonatal vitamin D status and risk of schizophrenia: A population-based case-control study. Archives of General Psychiatry, 67 (9), 889-894. doi: 10.1001/archgenpsychiatry.2010.110

Neonatal vitamin D status and risk of schizophrenia: A population-based case-control study

Featured

2010

Journal Article

Advanced paternal age is associated with alterations in discrete behavioural domains and cortical neuroanatomy of C57BL/6J mice

Foldi, Claire J., Eyles, Darryl W., McGrath, John J. and Burne, Thomas H. J. (2010). Advanced paternal age is associated with alterations in discrete behavioural domains and cortical neuroanatomy of C57BL/6J mice. European Journal of Neuroscience, 31 (3), 556-564. doi: 10.1111/j.1460-9568.2010.07074.x

Advanced paternal age is associated with alterations in discrete behavioural domains and cortical neuroanatomy of C57BL/6J mice

Featured

2009

Journal Article

Advanced paternal age is associated with impaired neurocognitive outcomes during infancy and childhood

Saha, Sukanta, Barnett, Adrian G., Foldi, Claire, Burne, Thomas H., Eyles, Darryl W., Buka, Stephen L. and McGrath, John J. (2009). Advanced paternal age is associated with impaired neurocognitive outcomes during infancy and childhood. PLoS Medicine, 6 (3), 0303-0311. doi: 10.1371/journal.pmed.1000040

Advanced paternal age is associated with impaired neurocognitive outcomes during infancy and childhood

Featured

2008

Journal Article

Olfactory mucosa is a potential source for autologous stem cell therapy for Parkinson's disease

Murrell, Wayne, Wetzig, Andrew, Donnellan, Michael, Féron, François, Burne, Tom, Meedeniya, Adrian, Kesby, James, Bianco, John, Perry, Chris, Silburn, Peter and Mackay-Sim, Alan (2008). Olfactory mucosa is a potential source for autologous stem cell therapy for Parkinson's disease. Stem Cells, 26 (8), 2183-2192. doi: 10.1634/stemcells.2008-0074

Olfactory mucosa is a potential source for autologous stem cell therapy for Parkinson's disease

Featured

2007

Journal Article

Vitamin D deficiency during various stages of pregnancy in the rat: Its impact on development and behavior in adult offspring

O'Loan, Jonathan, Eyles, Darryl W., Kesby, James, Ko, Pauline, McGrath, John J. and Burne, Thomas H. J. (2007). Vitamin D deficiency during various stages of pregnancy in the rat: Its impact on development and behavior in adult offspring. Psychoneuroendocrinology, 32 (3), 227-234. doi: 10.1016/j.psyneuen.2006.12.006

Vitamin D deficiency during various stages of pregnancy in the rat: Its impact on development and behavior in adult offspring

Featured

2006

Journal Article

Developmental vitamin D deficiency alters MK 801-induced hyperlocomotion in the adult rat: An animal model of schizophrenia

Kesby, James P., Burne, Thomas H.J., McGrath, John J. and Eyles, Darryl W. (2006). Developmental vitamin D deficiency alters MK 801-induced hyperlocomotion in the adult rat: An animal model of schizophrenia. Biological Psychiatry, 60 (6), 591-596. doi: 10.1016/j.biopsych.2006.02.033

Developmental vitamin D deficiency alters MK 801-induced hyperlocomotion in the adult rat: An animal model of schizophrenia

2024

Journal Article

Polycomb repressive complex 2 is critical for mouse cortical glutamatergic neuron development

Currey, Laura, Mitchell, Benjamin, Al-Khalily, Majd, McElnea, Sarah-Jayne, Kozulin, Peter, Harkins, Danyon, Pelenyi, Alexandra, Fenlon, Laura, Suarez, Rodrigo, Kurniawan, Nyoman D, Burne, Thomas H, Harris, Lachlan, Thor, Stefan and Piper, Michael (2024). Polycomb repressive complex 2 is critical for mouse cortical glutamatergic neuron development. Cerebral Cortex, 34 (7) ARTN bhae268. doi: 10.1093/cercor/bhae268

Polycomb repressive complex 2 is critical for mouse cortical glutamatergic neuron development

2024

Journal Article

The dynamic strategy shifting task: Optimisation of an operant task for assessing cognitive flexibility in rats

Flintoff, Jonathan Martin, Alexander, Suzy, Kesby, James Paul and Burne, Thomas Henry (2024). The dynamic strategy shifting task: Optimisation of an operant task for assessing cognitive flexibility in rats. Frontiers in Psychiatry, 15 1303728. doi: 10.3389/fpsyt.2024.1303728

The dynamic strategy shifting task: Optimisation of an operant task for assessing cognitive flexibility in rats

2024

Journal Article

Perineuronal nets are associated with decision making under conditions of uncertainty in female but not male mice

Mayne, Phoebe, Das, Joyosmita, Zou, Simin, Sullivan, Robert K.P. and Burne, Thomas H.J. (2024). Perineuronal nets are associated with decision making under conditions of uncertainty in female but not male mice. Behavioural Brain Research, 461 114845. doi: 10.1016/j.bbr.2024.114845

Perineuronal nets are associated with decision making under conditions of uncertainty in female but not male mice

2024

Book Chapter

Adult vitamin D deficiency and adverse brain outcomes

Mayne, Phoebe, Bradford, Dana, Groves, Natalie J., McGrath, John J. and Burne, Thomas H.J. (2024). Adult vitamin D deficiency and adverse brain outcomes. Feldman and Pike' s vitamin D: volume one: biochemistry, physiology and diagnostics. (pp. 975-996) edited by Martin Hewison, Roger Bouillon, Edward Giovannucci, David Goltzman, Mark Meyer and JoEllen Welsh. London, United Kingdom: Elsevier. doi: 10.1016/b978-0-323-91386-7.00035-0

Adult vitamin D deficiency and adverse brain outcomes

2023

Journal Article

Antagonism of D2 receptors via raclopride ameliorates amphetamine-induced associative learning deficits in male mice

Conn, Kyna-Anne, Alexander, Suzy, Burne, Thomas H.J. and Kesby, James P. (2023). Antagonism of D2 receptors via raclopride ameliorates amphetamine-induced associative learning deficits in male mice. Behavioural Brain Research, 454 114649, 114649. doi: 10.1016/j.bbr.2023.114649

Antagonism of D2 receptors via raclopride ameliorates amphetamine-induced associative learning deficits in male mice

2023

Journal Article

Activity in the dorsomedial striatum underlies serial reversal learning performance under probabilistic uncertainty

Young, Madison K., Conn, Kyna-Anne, Das, Joyosmita, Zou, Simin, Alexander, Suzy, Burne, Thomas H.J. and Kesby, James P. (2023). Activity in the dorsomedial striatum underlies serial reversal learning performance under probabilistic uncertainty. Biological Psychiatry Global Open Science, 3 (4), 1030-1041. doi: 10.1016/j.bpsgos.2022.08.005

Activity in the dorsomedial striatum underlies serial reversal learning performance under probabilistic uncertainty

2023

Journal Article

Synthetic anti-cocaine nanoaccine successfully prevents cocaine-induced hyperlocomotion

Madge, Harrison Y. R., Alexander, Suzy, Azuar, Armira, Zhang, Jiahui, Koirala, Prashamsa, Burne, Thomas H., Toth, Istvan and Stephenson, Rachel J. (2023). Synthetic anti-cocaine nanoaccine successfully prevents cocaine-induced hyperlocomotion. Journal of Medicinal Chemistry, 66 (17), 12407-12419. doi: 10.1021/acs.jmedchem.3c00889

Synthetic anti-cocaine nanoaccine successfully prevents cocaine-induced hyperlocomotion

2023

Journal Article

Activating the dorsomedial and ventral midbrain projections to the striatum differentially impairs goal-directed action in male mice

Conn, Kyna-Anne, Zou, Simin, Das, Joyosmita, Alexander, Suzy, Burne, Thomas HJ. and Kesby, James P. (2023). Activating the dorsomedial and ventral midbrain projections to the striatum differentially impairs goal-directed action in male mice. Neuropharmacology, 234 109550, 109550. doi: 10.1016/j.neuropharm.2023.109550

Activating the dorsomedial and ventral midbrain projections to the striatum differentially impairs goal-directed action in male mice

Funding

Current funding

  • 2023 - 2025
    Lab based analysis of rodent blood and tissue in a rodent model of fetal growth restriction (FGR)
    CSIRO
    Open grant
  • 2023 - 2026
    Reverse translation of a rodent cognitive flexibility task
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2018
    A specialised surgical and behavioural facility for longitudinal, multimodal examination of the rodent brain
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017
    Voltage-gated calcium channels and vitamin D: investigating the convergent links between risk factors for schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2016 - 2019
    Delayed radial glial maturation linked to NFI deficiency as an underlying cause of cortical defects in humans and mice
    NHMRC Project Grant
    Open grant
  • 2016
    Light-sheet microscope for high-speed 3D imaging of live organisms and fixed tissue
    NHMRC Equipment Grant
    Open grant
  • 2016 - 2020
    Voltage gated calcium channels and vitamin D: exploring the convergent links between risk factors for schizophrenia
    NHMRC Project Grant
    Open grant
  • 2015
    Reverse translation of cognitive tasks for animal models of neuropsychiatric disorders
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2015
    A sensitive, high resolution QTOF mass spectrometer with nanoUPLC system for qualitative and quantitative biomolecule analysis.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Does adult vitamin D deficiency increase vulnerability to social stress resulting in altered brain function?
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    Adult vitamin D deficiency and cognitive dysfunction in a mouse model
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    The Developmental vitamin D-deficiency animal model of schizophrenia:- Critical window for intervention and optimal dose
    NHMRC Project Grant
    Open grant
  • 2014
    Touchscreen-automated cognitive testing for mice
    NHMRC Equipment Grant
    Open grant
  • 2013 - 2016
    Early pharmacological intervention in an animal model of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2012 - 2015
    Developmental vitamin D deficiency and prefrontal cortical dysfunction
    NHMRC Project Grant
    Open grant
  • 2011
    Advanced behavioural facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011
    An automated liquid handling platform for High-throughput Preparation of multiplexed targeted sequence capture DNA libraries for Next-Generation DNA Sequencing (NGS)
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2014
    Attentional processing in developmentally vitamin D deficient rats: Modelling the cognitive symptoms of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    Neonatal vitamin D status and risk of schizophrenia: a replication in two independent samples
    NHMRC Project Grant
    Open grant
  • 2010
    Zebrafish Aquarium - expand capacity of existing Zebrafish facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2011
    Zebrafish behavioural suite
    UQ Major Equipment and Infrastructure
    Open grant
  • 2009 - 2012
    Advanced paternal age: behavioural, neuroanatomical and genomic correlates in the offspring of older fathers
    NHMRC Project Grant
    Open grant
  • 2007 - 2009
    The Developmental vitamin D model (DVD) as an animal model for schizophrenia
    NHMRC Project Grant
    Open grant

Supervision

Availability

Professor Thomas Burne is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Measuring cognitive flexibility in rodents

    Principal Advisor

    Other advisors: Professor Dan Siskind

  • Doctor Philosophy

    The neural basis of predictive coding: Defining how the brain uses feedback to propagate predictions

    Associate Advisor

    Other advisors: Dr Clarissa Whitmire

Completed supervision

Media

Enquiries

Contact Professor Thomas Burne directly for media enquiries about:

  • Animal behaviour
  • Animal models
  • Behaviour in animals
  • Behavioural neuroscience
  • Behavioural phenotyping
  • Neuroscience - behavioural
  • Phenotyping - behavioural
  • Schizophrenia

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