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Professor Thomas Burne
Professor

Thomas Burne

Email: 

Overview

Background

Professor Burne is a leading Australian researcher in the field of biological psychiatry. Prof. Burne has >150 peer reviewed publications, which have attracted over 8500 citations (H-index 50). His research impact is evident by his 11 papers with >200 citations, with two recognised as Web of Science ‘Highly Cited Papers’. Together with collaborators he has been awarded >$8 million in research funding. Since 2003 he has supervised 17 PhD students, and 28 honours students Prof. Burne has a broad background in behavioural neuroscience, with specific training and expertise in animal models. As a Professorial Research Fellow with the Queensland Centre for Mental Health Research and Group Leader at the Queensland Brain Institute (QBI) the focus of his research includes cognitive testing in rodent models of neuropsychiatric disorders, such as schizophrenia, as well as psychopharmacological studies and research on clinical populations. As a CI on several university- and NHMRC-funded grants, he has helped establish infrastructure at QBI for behavioural assessment and methods of automated operant-based cognitive tests in rodents. Prof. Burne is a past president of Biological Psychiatry Australia, he is the Queensland representative for the Australasian Neuroscience Society, and he is a member of the NHMRC Animal Welfare Committee.

Prof. Burne’s group studies brain development and behaviour in animal models to learn more about neuropsychiatric diseases, such as schizophrenia. Research is focused on investigating the underlying biological basis for schizophrenia, with the goal of finding public health interventions that will alleviate the burden of this disease. The group has been exploring the impact of developmental vitamin D (DVD) deficiency on brain development, the impact of adult vitamin D deficiency on brain function and behaviour, and the neurobiological affects of having an older father. More recently his group has been focussed on assessing cognitive function in rodents. Prof. Burne’s research is carried out in close collaboration with Professors John McGrath and Darryl Eyles, in a multidisciplinary team. Together they have an integrated research program using a broad range of neuroscientific techniques to explore potential causes of schizophrenia. There is a particular focus on early life, nongenetic risk factors and the team has skills in epidemiology, psychiatry, neuroanatomy, molecular biology, developmental biology and behavioural neuroscience. The Burne group is currently developing animal models related to risk factors for schizophrenia and autism.

Availability

Professor Thomas Burne is:
Available for supervision
Media expert

Fields of research

Works

Search Professor Thomas Burne’s works on UQ eSpace

222 works between 1996 and 2024

61 - 80 of 222 works

2017

Journal Article

Effect of the glucocorticoid receptor antagonist RU486 on MK-801 induced behavioural sensitization

Lefevre, Emilia M., Medley, Gregory A., Reeks, Timothy, Alexander, Suzy, Burne, Thomas H. J. and Eyles, Darryl W. (2017). Effect of the glucocorticoid receptor antagonist RU486 on MK-801 induced behavioural sensitization. PLoS One, 12 (4) e0176156, e0176156. doi: 10.1371/journal.pone.0176156

Effect of the glucocorticoid receptor antagonist RU486 on MK-801 induced behavioural sensitization

2017

Journal Article

Baseline-dependent effects of amphetamine on attention are associated with striatal dopamine metabolism

Turner, Karly M., Peak, James and Burne, Thomas H. J. (2017). Baseline-dependent effects of amphetamine on attention are associated with striatal dopamine metabolism. Scientific Reports, 7 (1) 297, 297. doi: 10.1038/s41598-017-00437-9

Baseline-dependent effects of amphetamine on attention are associated with striatal dopamine metabolism

2017

Journal Article

The impact of vitamin D deficiency on neurogenesis in the adult brain

Groves, Natalie J. and Burne, Thomas H. J. (2017). The impact of vitamin D deficiency on neurogenesis in the adult brain. Neural Regeneration Research, 12 (3), 393-394. doi: 10.4103/1673-5374.202936

The impact of vitamin D deficiency on neurogenesis in the adult brain

2017

Journal Article

Gestational vitamin D deficiency and autism spectrum disorder

Vinkhuyzen, Anna A. E., Eyles, Darryl W., Burne, Thomas H. J., Blanken, Laura M. E., Kruithof, Claudia J., Verhulst, Frank, White, Tonya, Jaddoe, Vincent W., Tiemeier, Henning and McGrath, John J. (2017). Gestational vitamin D deficiency and autism spectrum disorder. BJPsych Open, 3 (2), 85-90. doi: 10.1192/bjpo.bp.116.004077

Gestational vitamin D deficiency and autism spectrum disorder

2017

Journal Article

BALB/c mice can learn touchscreen visual discrimination and reversal tasks faster than C57BL/6 mice

Turner, Karly M., Simpson, Christopher G. and Burne, Thomas H. J. (2017). BALB/c mice can learn touchscreen visual discrimination and reversal tasks faster than C57BL/6 mice. Frontiers in Behavioral Neuroscience, 11 16, 16. doi: 10.3389/fnbeh.2017.00016

BALB/c mice can learn touchscreen visual discrimination and reversal tasks faster than C57BL/6 mice

2017

Journal Article

Impact of combined adult vitamin D deficiency and second-hit exposures on brain function

Al-Amin, Md Mamun, Sullivan, Robert K. P., Jaeschke, Kara N. and Burne, Thomas H. J. (2017). Impact of combined adult vitamin D deficiency and second-hit exposures on brain function. CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources, 12 (040), 1-16. doi: 10.1079/PAVSNNR201712040

Impact of combined adult vitamin D deficiency and second-hit exposures on brain function

2016

Journal Article

Transcriptional regulation of intermediate progenitor cell generation during hippocampal development

Harris, Lachlan, Zalucki, Oressia, Gobius, Ilan, McDonald, Hannah, Osinki, Jason, Harvey, Tracey J., Essebier, Alexandra, Vidovic, Diana, Gladwyn-Ng, Ivan, Burne, Thomas H., Heng, Julian I., Richards, Linda J., Gronostajski, Richard M. and Piper, Michael (2016). Transcriptional regulation of intermediate progenitor cell generation during hippocampal development. Development, 143 (24), 4620-4630. doi: 10.1242/dev.140681

Transcriptional regulation of intermediate progenitor cell generation during hippocampal development

2016

Journal Article

Gestational vitamin D deficiency and autism-related traits: the Generation R Study

Vinkhuyzen, A. A. E., Eyles, D. W., Burne, T. H. J., Blanken, L. M. E., Kruithof, C. J., Verhulst, F., Jaddoe, V. W., Tiemeier, H. and McGrath, J. J. (2016). Gestational vitamin D deficiency and autism-related traits: the Generation R Study. Molecular Psychiatry, 23 (2), 240-246. doi: 10.1038/mp.2016.213

Gestational vitamin D deficiency and autism-related traits: the Generation R Study

2016

Journal Article

Risperidone induces long-lasting changes in the conditioned avoidance response and accumbal gene expression selectively in animals treated as adolescents

Moe, Aung Aung Kywe, Kurniawan, Nyoman D., Alexander, Suzanne, Cui, Xiaoying, Burne, Thomas H. J. and Eyles, Darryl W. (2016). Risperidone induces long-lasting changes in the conditioned avoidance response and accumbal gene expression selectively in animals treated as adolescents. Neuropharmacology, 108, 264-274. doi: 10.1016/j.neuropharm.2016.04.035

Risperidone induces long-lasting changes in the conditioned avoidance response and accumbal gene expression selectively in animals treated as adolescents

2016

Journal Article

Improvement of attention with amphetamine in low- and high-performing rats

Turner, Karly M. and Burne, Thomas H. J. (2016). Improvement of attention with amphetamine in low- and high-performing rats. Psychopharmacology, 233 (18), 3383-3394. doi: 10.1007/s00213-016-4376-9

Improvement of attention with amphetamine in low- and high-performing rats

2016

Journal Article

Neural changes induced by antipsychotic administration in adolescence: a review of studies in laboratory rodents

Moe, Aung Aung Kywe, Scott, James G., Burne, Thomas H. J. and Eyles, Darryl W. (2016). Neural changes induced by antipsychotic administration in adolescence: a review of studies in laboratory rodents. Journal of Psychopharmacology, 30 (8), 771-794. doi: 10.1177/0269881116654776

Neural changes induced by antipsychotic administration in adolescence: a review of studies in laboratory rodents

2016

Journal Article

Maternal vitamin D concentrations during pregnancy, fetal growth patterns, and risks of adverse birth outcomes

Miliku, Kozeta, Vinkhuyzen, Anna, Blanken, Laura M. E., McGrath, John J., Eyles, Darryl W., Burne, Thomas H., Hofman, Albert, Tiemeier, Henning, Steegers, Eric A. P., Gaillard, Romy and Jaddoe, Vincent W. V. (2016). Maternal vitamin D concentrations during pregnancy, fetal growth patterns, and risks of adverse birth outcomes. American Journal of Clinical Nutrition, 103 (6), 1514-1522. doi: 10.3945/ajcn.115.123752

Maternal vitamin D concentrations during pregnancy, fetal growth patterns, and risks of adverse birth outcomes

2016

Journal Article

Usp9x-deficiency disrupts the morphological development of the postnatal hippocampal dentate gyrus

Oishi, Sabrina, Premaratne, Susitha, Harvey, Tracey J., Iyer, Swati, Dixon, Chantelle, Alexander, Suzanne, Burne, Thomas H. J., Wood, Stephen A. and Piper, Michael (2016). Usp9x-deficiency disrupts the morphological development of the postnatal hippocampal dentate gyrus. Scientific Reports, 6 (1) 25783, 25783.1-25783.13. doi: 10.1038/srep25783

Usp9x-deficiency disrupts the morphological development of the postnatal hippocampal dentate gyrus

2016

Journal Article

Associations of maternal and fetal 25-hydroxyvitamin D levels with childhood eczema: The Generation R Study

Gazibara, Tatjana, Elbert, Niels J., den Dekker, Herman T., de Jongste, Johan C., Reiss, Irwin, McGrath, John J., Eyles, Darryl W., Burne, Thomas H., Tiemeier, Henning, Jaddoe, Vincent W. V., Pasmans, Suzanne G. M. A. and Duijts, Liesbeth (2016). Associations of maternal and fetal 25-hydroxyvitamin D levels with childhood eczema: The Generation R Study. Pediatric Allergy and Immunology, 27 (3), 283-289. doi: 10.1111/pai.12530

Associations of maternal and fetal 25-hydroxyvitamin D levels with childhood eczema: The Generation R Study

2016

Journal Article

Behavioural effects of adult Vitamin D deficiency in BALB/c mice are not associated with proliferation or survival of neurons in the adult hippocampus

Groves, Natalie J., Bradford, DanaKai, Sullivan, Robert K. P., Conn, Kyna-Anne, Aljelaify, Rasha Fahad, McGrath, John J. and Burne, Thomas H. J. (2016). Behavioural effects of adult Vitamin D deficiency in BALB/c mice are not associated with proliferation or survival of neurons in the adult hippocampus. PLoS ONE, 11 (4) e0152328, e0152328. doi: 10.1371/journal.pone.0152328

Behavioural effects of adult Vitamin D deficiency in BALB/c mice are not associated with proliferation or survival of neurons in the adult hippocampus

2016

Journal Article

Sex-specific attentional deficits in adult vitamin D deficient BALB/c mice

Groves, Natalie J. and Burne, Thomas H. J. (2016). Sex-specific attentional deficits in adult vitamin D deficient BALB/c mice. Physiology and Behavior, 157, 94-101. doi: 10.1016/j.physbeh.2016.01.033

Sex-specific attentional deficits in adult vitamin D deficient BALB/c mice

2016

Journal Article

Behavioural sensitisation to MK-801 is dose-dependent and independent of environmental context

Lefevre, Emilia M., Eyles, Darryl W. and Burne, Thomas H. J. (2016). Behavioural sensitisation to MK-801 is dose-dependent and independent of environmental context. Behavioural Brain Research, 298 (Part B), 241-245. doi: 10.1016/j.bbr.2015.11.014

Behavioural sensitisation to MK-801 is dose-dependent and independent of environmental context

2016

Journal Article

The impact of vitamin D deficiency on behaviour and brain function in rodents

Overeem, Kathie, Eyles, Darryl W., McGrath, John J. and Burne, Thomas H. J. (2016). The impact of vitamin D deficiency on behaviour and brain function in rodents. Current Opinion in Behavioral Sciences, 7, 47-52. doi: 10.1016/j.cobeha.2015.11.012

The impact of vitamin D deficiency on behaviour and brain function in rodents

2016

Journal Article

Associations of maternal and fetal 25-hydroxyvitamin D levels with childhood lung function and asthma: the Generation R Study

Gazibara, Tatjana, den Dekker, Herman T., de Jongste, Johan C., McGrath, John J., Eyles, Darryl W., Burne, Thomas H., Reiss, Irwin, Franco, Oscar H., Tiemeier, Henning, Jaddoe, Vincent W. V. and Duijts, Liesbeth (2016). Associations of maternal and fetal 25-hydroxyvitamin D levels with childhood lung function and asthma: the Generation R Study. Clinical and Experimental Allergy, 46 (2), 337-346. doi: 10.1111/cea.12645

Associations of maternal and fetal 25-hydroxyvitamin D levels with childhood lung function and asthma: the Generation R Study

2016

Journal Article

Measuring attention in rodents: comparison of a modified signal detection task and the 5-choice serial reaction time task

Turner, Karly M., Peak, James and Burne, Thomas H. J. (2016). Measuring attention in rodents: comparison of a modified signal detection task and the 5-choice serial reaction time task. Frontiers in Behavioral Neuroscience, 9 (370) 370, 1-10. doi: 10.3389/fnbeh.2015.00370

Measuring attention in rodents: comparison of a modified signal detection task and the 5-choice serial reaction time task

Funding

Current funding

  • 2023 - 2025
    Lab based analysis of rodent blood and tissue in a rodent model of fetal growth restriction (FGR)
    CSIRO
    Open grant
  • 2023 - 2026
    Reverse translation of a rodent cognitive flexibility task
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2018
    A specialised surgical and behavioural facility for longitudinal, multimodal examination of the rodent brain
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017
    Voltage-gated calcium channels and vitamin D: investigating the convergent links between risk factors for schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2016 - 2019
    Delayed radial glial maturation linked to NFI deficiency as an underlying cause of cortical defects in humans and mice
    NHMRC Project Grant
    Open grant
  • 2016
    Light-sheet microscope for high-speed 3D imaging of live organisms and fixed tissue
    NHMRC Equipment Grant
    Open grant
  • 2016 - 2020
    Voltage gated calcium channels and vitamin D: exploring the convergent links between risk factors for schizophrenia
    NHMRC Project Grant
    Open grant
  • 2015
    Reverse translation of cognitive tasks for animal models of neuropsychiatric disorders
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2015
    A sensitive, high resolution QTOF mass spectrometer with nanoUPLC system for qualitative and quantitative biomolecule analysis.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Does adult vitamin D deficiency increase vulnerability to social stress resulting in altered brain function?
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    Adult vitamin D deficiency and cognitive dysfunction in a mouse model
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    The Developmental vitamin D-deficiency animal model of schizophrenia:- Critical window for intervention and optimal dose
    NHMRC Project Grant
    Open grant
  • 2014
    Touchscreen-automated cognitive testing for mice
    NHMRC Equipment Grant
    Open grant
  • 2013 - 2016
    Early pharmacological intervention in an animal model of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2012 - 2015
    Developmental vitamin D deficiency and prefrontal cortical dysfunction
    NHMRC Project Grant
    Open grant
  • 2011
    Advanced behavioural facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011
    An automated liquid handling platform for High-throughput Preparation of multiplexed targeted sequence capture DNA libraries for Next-Generation DNA Sequencing (NGS)
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2014
    Attentional processing in developmentally vitamin D deficient rats: Modelling the cognitive symptoms of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    Neonatal vitamin D status and risk of schizophrenia: a replication in two independent samples
    NHMRC Project Grant
    Open grant
  • 2010
    Zebrafish Aquarium - expand capacity of existing Zebrafish facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2011
    Zebrafish behavioural suite
    UQ Major Equipment and Infrastructure
    Open grant
  • 2009 - 2012
    Advanced paternal age: behavioural, neuroanatomical and genomic correlates in the offspring of older fathers
    NHMRC Project Grant
    Open grant
  • 2007 - 2009
    The Developmental vitamin D model (DVD) as an animal model for schizophrenia
    NHMRC Project Grant
    Open grant

Supervision

Availability

Professor Thomas Burne is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Measuring cognitive flexibility in rodents

    Principal Advisor

    Other advisors: Professor Dan Siskind

  • Doctor Philosophy

    The neural basis of predictive coding: Defining how the brain uses feedback to propagate predictions

    Associate Advisor

    Other advisors: Dr Clarissa Whitmire

Completed supervision

Media

Enquiries

Contact Professor Thomas Burne directly for media enquiries about:

  • Animal behaviour
  • Animal models
  • Behaviour in animals
  • Behavioural neuroscience
  • Behavioural phenotyping
  • Neuroscience - behavioural
  • Phenotyping - behavioural
  • Schizophrenia

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