Overview
Background
Prof Siskind trained as a psychiatrist in Australia and the United States. He graduated from medicine at the University of Queensland in 1998. After working with Doctors Without Borders in Chechnya in 2000, he became interested in psychiatry. He moved to Boston in 2002, where he did his psychiatry residency at Boston University and a Master of Public Health at Harvard University. He returned to Brisbane in June 2008 as a clinical academic psychiatrist at the Metro South Addiction and Mental Health Service. He completed his Ph.D in Feb 2014. His research interests include clozapine and treatment refractory schizophrenia, the physical health of people with severe and persistent mental illness, supported accommodation, assertive community treatment and mental health services research. He was awarded an NHMRC Investigator Grant as a Leadership Fellow (L1 2027-2031) an Emerging Leadership Fellow (EL2 2021-2025) and an NHMRC Early Career Fellowship (ECF 2016-2019). He has a current CIA MRFF RCRDUN grant looking at treatments to reduce cardiometabolic morbidity among people with schizophrenia. He was the SIRS 2026 Outstanding Clinical and Community Research Award recipient, and was elected to the Australian Academy of Health and Medical Sciences in 2025. He has over 350 peer reviewed publications, including first author in the highly ranked Lancet, World Psychiatry, Lancet Psychiatry, BJPsych, ANZJP, & Schizophrenia Bulletin. He is a named investigator on over $65 million in competitive research grants, with over $9 million as CIA.
Availability
- Professor Dan Siskind is:
- Available for supervision
- Media expert
Fields of research
Research interests
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Schizophrenia
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Physical Health Comorbidity
Research impacts
Prof Siskind's research has had direct, measurable impact on clinical practice and policy. His landmark studies on clozapine-associated neutropenia demonstrated that routine monitoring could safely cease after two years, evidence that has driven the removal of long-term monitoring mandates by regulators — improving safe and quality access to clozapine for more than 2.5 million people globally. His work establishing optimal plasma clozapine reference ranges is now used by pathology providers across Australia, while his findings on antipsychotic-associated metabolic risk and weight gain have been incorporated into international guidelines and adopted into clinical practice, with metformin augmentation now regularly prescribed for patients commencing antipsychotics. His Lancet Psychiatry Commission on physical health in people with mental illness helped set the global agenda for integrating physical and mental healthcare, informing policy from the WHO, OECD, and across multiple countries. As Chair of the INTEGRATE Steering Committee, he led development of the first consensus-based, algorithmic international guidelines for schizophrenia treatment, which have been endorsed by peak bodies. Through sustained engagement with regulators, professional colleges and health services, Prof Siskind has ensured his research translates rapidly from bench to bedside to policy, cementing his reputation as a global leader in schizophrenia care.
Works
Search Professor Dan Siskind’s works on UQ eSpace
2026
Journal Article
Efficacy and safety outcomes of different plasma clozapine and norclozapine levels in schizophrenia spectrum disorder: a dose-response meta-analysis exploring “critical” levels
Fornaro, Michele, Lorenzo, Chiara Di, Siskind, Dan and de Bartolomeis, Andrea (2026). Efficacy and safety outcomes of different plasma clozapine and norclozapine levels in schizophrenia spectrum disorder: a dose-response meta-analysis exploring “critical” levels. Psychiatry Research, 365 117340, 1-16. doi: 10.1016/j.psychres.2026.117340
2026
Journal Article
Prevalence and outcomes of co-occurring psychiatric and endocrine, metabolic, and nutritional disorders: An atlas based on umbrella review of 254,154,533 records
Fornaro, Michele, Di Lorenzo, Chiara, Steardo, Luca, Veronese, Nicola, Stubbs, Brendon, Vancampfort, Davy, Siskind, Dan and Solmi, Marco (2026). Prevalence and outcomes of co-occurring psychiatric and endocrine, metabolic, and nutritional disorders: An atlas based on umbrella review of 254,154,533 records. European Neuropsychopharmacology, 110 112880, 112880-110. doi: 10.1016/j.euroneuro.2026.112880
2026
Journal Article
Temporal patterns and risk factors of clozapine-associated neutropenia: a nationwide population-based cohort study
Wu, Chi-Shin, Northwood, Korinne, Wu, Ming-Shiang, Wang, Shi-Heng, Huang, Wei-Lieh, Liu, Chen-Chung and Siskind, Dan (2026). Temporal patterns and risk factors of clozapine-associated neutropenia: a nationwide population-based cohort study. The Lancet Regional Health - Western Pacific, 74 101970, 101970-74. doi: 10.1016/j.lanwpc.2026.101970
2026
Journal Article
Incidence of systemic physical multimorbidity among people with schizophrenia-spectrum or bipolar-spectrum disorders compared with age-matched and sex-matched individuals in Queensland, Australia: a statewide, hospital cohort study
Halstead, Sean, Warren, Nicola, Kisely, Steve, Arnautovska, Urska, Trott, Mike, Correll, Christoph U., Ebdrup, Bjorn H., Heffernan, Ed, Mohr, Grímur Hognason, McCutcheon, Robert A., Morley, Katherine I., O’Donoghue, Brian, Pillinger, Toby, Sara, Grant, Taipale, Heidi and Siskind, Dan (2026). Incidence of systemic physical multimorbidity among people with schizophrenia-spectrum or bipolar-spectrum disorders compared with age-matched and sex-matched individuals in Queensland, Australia: a statewide, hospital cohort study. The Lancet Psychiatry, 13 (9), 771-782. doi: 10.1016/s2215-0366(26)00196-3
2026
Journal Article
Incidence of clozapine-associated neutropenia in patients with schizophrenia: 20-year population-based study in Hong Kong
Zhou, Huiquan, Luo, Hao, Siskind, Dan, Northwood, Korinne, Tang, Jennifer Yee-Man, Lui, Simon S. Y., Lee, Edwin H. M., Kan, Chui-Kwan, Tsui, Chi Fong, Poon, Lap Tak, Leung, Shuk Yan Joey, Wong, Yip Chau, Wong, Jessica Oi Yin and Chan, Sherry Kit Wa (2026). Incidence of clozapine-associated neutropenia in patients with schizophrenia: 20-year population-based study in Hong Kong. The British Journal of Psychiatry, 1-8. doi: 10.1192/bjp.2026.10726
2026
Journal Article
Hospitalisation and mortality outcomes after second COVID-19 vaccination among Australians living with severe mental illness: Findings from a matched case–control study using national data linkage
Bull, Claudia, Wheeler, Amanda J., Palmer, Victoria J., Lewis, Matthew, Siskind, Dan and Kisely, Steve (2026). Hospitalisation and mortality outcomes after second COVID-19 vaccination among Australians living with severe mental illness: Findings from a matched case–control study using national data linkage. Australian and New Zealand Journal of Psychiatry 00048674261475206, 48674261475206-48674261475206. doi: 10.1177/00048674261475206
2026
Journal Article
Duration of untreated illness in eating disorders: a comprehensive systematic review and meta-regression
de Geus, Gyselle, Trott, Mike, Monteleone, Alessio Maria, Firth, Joseph, Siskind, Dan, Teasdale, Scott, Arnautovska, Urska, Iyer, Ravi, Stubbs, Brendon, Demidenko, Natasha, Martin, David, Antochi, Ruxandra, Fiedorowicz, Jess G., Austin, Amelia, Schmidt, Ulrike, Wade, Tracey, Fernandez-Aranda, Fernando, Herpertz-Dahlmann, Beate, Hoek, Hans W., Voderholzer, Ulrich, Kolar, David, Zipfel, Stephan, Pike, Kathleen M., Karwautz, Andreas, Wonderlich, Stephen, Smith, Lee, Carfagno, Marco and Solmi, Marco (2026). Duration of untreated illness in eating disorders: a comprehensive systematic review and meta-regression. Journal of Eating Disorders. doi: 10.1186/s40337-026-01731-6
2026
Journal Article
The experiences of people diagnosed with severe mental illness and colorectal cancer: a qualitative study
Zirnsak, Tessa-May, De Nicola, Julia, Kisely, Steve, Siskind, Dan, Protani, Melinda M. and Brophy, Lisa (2026). The experiences of people diagnosed with severe mental illness and colorectal cancer: a qualitative study. Australasian Psychiatry, 34 (4), 336-342. doi: 10.1177/10398562251406026
2026
Journal Article
Management of clozapine-resistant schizophrenia
Lally, John, Gee, Siobhan, Hynes-Ryan, Caroline, Northwood, Korinne, Keating, Dolores, Suetani, Shuichi, Siskind, Dan and O’Donoghue, Brian (2026). Management of clozapine-resistant schizophrenia. Australian and New Zealand Journal of Psychiatry, 48674261462755. doi: 10.1177/00048674261462755
2026
Journal Article
Interventions for smoking cessation in inpatient psychiatry settings
Plever, Sally, Kisely, Steve R, Bonevski, Billie, Siskind, Dan, Yamazaki-Tan, Julia, Thaker, Parth, Vos, Greta, Kim, Doyoon, Guillaumier, Ashleigh and Gartner, Coral E (2026). Interventions for smoking cessation in inpatient psychiatry settings. Cochrane Database of Systematic Reviews, 2026 (7), CD015934. doi: 10.1002/14651858.cd015934.pub2
2026
Journal Article
Reevaluating Clozapine-Induced QT Prolongation
Tanzer, Timothy, Hanisch, Rebecca, Yap, Chloe, Warren, Nicola, Barras, Michael, Kisely, Steve, Isoardi, Katherine, Kosari, Kiana and Siskind, Dan (2026). Reevaluating Clozapine-Induced QT Prolongation. Schizophrenia Bulletin, 52 (4) sbaf114, 1-9. doi: 10.1093/schbul/sbaf114
2026
Journal Article
Protocol for the MyPREPED trial: hybrid type 2 effectiveness–implementation trial of a peer-delivered digital self-management tool (MyBRANCHES) for young people in Australia transitioning from early intervention in psychosis services
Milton, Alyssa, Brown, Ellie, Arnautovska, Urska, Vaughan, Priya, Gao, Caroline, Chatterton, Mary Lou, Stratton, Elizabeth, Hancock, Nicola, Chapman, Justin, Iyer, Ravi, Singh, Simran, Malhotra, Saahil, Batara, Sam, Chakma, Symphony, De Cicco, Deanna, Lindsay, Hadley, Harris, Anthony, Siskind, Dan, Warren, Nicola, McHugh, Cate, McArdle, Peter, Phung, Darren, Cook, Jim, Thompson, Andrew and Glozier, Nick (2026). Protocol for the MyPREPED trial: hybrid type 2 effectiveness–implementation trial of a peer-delivered digital self-management tool (MyBRANCHES) for young people in Australia transitioning from early intervention in psychosis services. BJPsych Open, 12 (4) e200, e200. doi: 10.1192/bjo.2026.12056
2026
Journal Article
Clinical Practice Guideline on the Pharmacological Management of Antipsychotic-Related Dyslipidemia
Carolan, Aoife, Hynes-Ryan, Caroline, Bourke, Rita, Columb, David, Cullen, Walter, deFerranti, Sarah, Harrington, Sophie Mae, Kelleher, Ian, Kennedy, Cormac, Khoury, Michael, Lally, John, Lyne, John, Norton, Michael, O’Connor, Karen, O’Connor, Patricia, O’Shea, Donal, Perry, Benjamin, Prendeville, Terence, Ryan, Cristin, Sadowska, Ewa, Shiers, David, Siskind, Dan, Strawbridge, Judith, Tae, Haeun, Keating, Dolores and O’Donoghue, Brian (2026). Clinical Practice Guideline on the Pharmacological Management of Antipsychotic-Related Dyslipidemia. Schizophrenia Bulletin, 52 (4) sbag086. doi: 10.1093/schbul/sbag086
2026
Journal Article
Research priorities for metabolic interventions in severe mental illness: results of a James Lind Alliance Priority Setting Partnership
Farran, Dina, Kapi, Maria, Moffat, Kate, Stratford, Melanie, Solangi, Sadaf, Walsh, Annabel E L, Campbell, Iain, Magee, Caroline, Siskind, Dan, Smith, Daniel, Gaughran, Fiona, Ismail, Khalida, Pillinger, Toby, Agarwal, Mahavir, Ashbrook, David, Berk, Michael, Burgess, Karl, Campbell, Iain, Farran, Dina, Ferguson, Amy, Fleetwood, Kelly, Gaughran, Fiona, Ismail, Khalida, Jackson, Caroline A., Kenney, Joanne P.M., Lightman, Stafford, Luz, Saturnino, Marx, Wolfgang, Oduguwa, Ifeoluwa ... Wyse, Cathy Wyse (2026). Research priorities for metabolic interventions in severe mental illness: results of a James Lind Alliance Priority Setting Partnership. The Lancet Psychiatry, 13 (9), 783-791. doi: 10.1016/s2215-0366(26)00129-x
2026
Journal Article
Natural disasters and suicidality in Australia: a systematic review
Trott, Mike, Lockett, C., Arnautovska, U., Kisely, S., Crompton, D. and Siskind, D. (2026). Natural disasters and suicidality in Australia: a systematic review. Social Psychiatry and Psychiatric Epidemiology, 1-12. doi: 10.1007/s00127-026-03160-x
2026
Journal Article
Effects of glucagon-like peptide-1 receptor agonists on anthropometric and adiposity measures in patients with antipsychotic-induced weight gain: a systematic review and meta-analysis
Lee, Songmin, Kim, Min-Gul, Trott, Mike, Siskind, Dan and Kim, Jae Hyun (2026). Effects of glucagon-like peptide-1 receptor agonists on anthropometric and adiposity measures in patients with antipsychotic-induced weight gain: a systematic review and meta-analysis. Journal of Psychopharmacology, 2698811261456190. doi: 10.1177/02698811261456190
2026
Journal Article
Do virtual reality-based therapies affect symptomatology and psychosocial functioning in schizophrenia spectrum disorders: systematic review and meta-analysis
Colgan, George Alexander, Ng, Kelvin Kwok Lap, Siskind, Dan, Trott, Mike and Arnautovska, Urska (2026). Do virtual reality-based therapies affect symptomatology and psychosocial functioning in schizophrenia spectrum disorders: systematic review and meta-analysis. BJPsych Open, 12 (4) e165, e165-e165. doi: 10.1192/bjo.2026.12012
2026
Journal Article
The feasibility of resistance training versus aerobic exercise in a rehabilitation setting for people living with psychotic disorders: A randomised controlled trial
Korman, Nicole, Stanton, Robert, Trott, Mike, Stubbs, Brendon, Baker, Andrea, Butler, Cassandra, Siskind, Dan, Rosenbaum, Simon, Firth, Joseph, Martland, Rebecca, McIntosh, Talia, Warren, Nicola, Heffernan, Edward, Dark, Frances and Chapman, Justin (2026). The feasibility of resistance training versus aerobic exercise in a rehabilitation setting for people living with psychotic disorders: A randomised controlled trial. Australian and New Zealand Journal of Psychiatry, 60 (6), 538-552. doi: 10.1177/00048674251361681
2026
Journal Article
Stimulant and medicinal cannabis prescribing in patients referred to an early psychosis service in Queensland: a brief report
McArdle, Peter, Trott, Mike, Warren, Nicola, De Silva, Dilprasan, Smith, Lesley, Ritchie, Sarah and Siskind, Dan (2026). Stimulant and medicinal cannabis prescribing in patients referred to an early psychosis service in Queensland: a brief report. Australasian Psychiatry, 34 (3), 253-257. doi: 10.1177/10398562251406048
2026
Journal Article
Effects of Semaglutide on Body Weight in Clozapine-Treated Individuals with Schizophrenia and Obesity: A Randomized Controlled Trial
Siskind, D., Trott, M. and Arnautovska, U. (2026). Effects of Semaglutide on Body Weight in Clozapine-Treated Individuals with Schizophrenia and Obesity: A Randomized Controlled Trial. European Psychiatry, 69 (S1), S110-S110. doi: 10.1192/j.eurpsy.2026.10638
Funding
Current funding
Supervision
Availability
- Professor Dan Siskind is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Food and nutrition security in individuals with severe mental illness
Principal Advisor
Other advisors: Dr Urska Arnautovska
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Doctor Philosophy
Manifestations, impacts, and clinical implications of physical multimorbidity in people living with severe mental illness
Principal Advisor
Other advisors: Associate Professor Nicola Warren, Professor Steve Kisely
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Master Philosophy
A quantitative and qualitative study of forensic orders in Queensland
Associate Advisor
Other advisors: Professor Steve Kisely, Dr Claudia Bull
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Doctor Philosophy
Smoking Cessation in People with a Serious Mental Illness
Associate Advisor
Other advisors: Professor Steve Kisely, Professor Coral Gartner
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Doctor Philosophy
Measuring cognitive flexibility in rodents
Associate Advisor
Other advisors: Professor Thomas Burne
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Doctor Philosophy
Management of myocarditis among people with schizophrenia commencing clozapine
Associate Advisor
Other advisors: Associate Professor Nicola Warren
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Doctor Philosophy
Genetic determinants of treatment outcomes in mental health: harnessing the shared genetic etiology of mental disorders for precision psychiatry.
Associate Advisor
Other advisors: Honorary Professor Sarah Medland
Completed supervision
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2026
Doctor Philosophy
The Quality and Safe Use of Clozapine
Principal Advisor
Other advisors: Associate Professor Nicola Warren, Professor Michael Barras, Professor Steve Kisely
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2025
Doctor Philosophy
Investigating clozapine rechallenge using granulocyte-colony stimulating factor in people previously experiencing clozapine-associated neutropenia.
Principal Advisor
Other advisors: Professor Steve Kisely
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2021
Doctor Philosophy
Psychiatric clinical decision making in anti-NMDA receptor encephalitis
Principal Advisor
Other advisors: Associate Professor Stefan Blum, Professor Steve Kisely
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2024
Doctor Philosophy
The Role of the Gut Microbiome in Psychiatric Illness: From Prenatal Risk Factors to Treatment Resistance
Associate Advisor
Other advisors: Honorary Professor Jake Gratten, Honorary Professor Darryl Eyles
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2023
Doctor Philosophy
Measuring and improving cognition in a rodent model relevant to schizophrenia
Associate Advisor
Other advisors: Dr James Kesby, Professor Thomas Burne
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2022
Doctor Philosophy
Nose-to-Brain Delivery of Clozapine in Sol-Gel Systems
Associate Advisor
Other advisors: Associate Professor Harendra Parekh, Dr Preeti Pandey, Dr James Robert Falconer
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2020
Doctor Philosophy
Exploring the characteristics and service needs of carers for adults with mental illness to inform mental health service planning
Associate Advisor
Other advisors: Associate Professor Meredith Harris
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2020
Doctor Philosophy
Who receives what, from whom, and to what effect at clinically operated, community-based residential mental health rehabilitation for Severe and Persistent Mental Illness in Australia?
Associate Advisor
Other advisors: Associate Professor Meredith Harris
Media
Enquiries
Contact Professor Dan Siskind directly for media enquiries about:
- Cardiometabolic co-morbidity of schizophrenia
- Treatment Refractory Schizophrenia
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