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Professor Dan Siskind
Professor

Dan Siskind

Email: 

Overview

Background

Prof Siskind trained as a psychiatrist in Australia and the United States. He graduated from medicine at the University of Queensland in 1998. After working with Doctors Without Borders in Chechnya in 2000, he became interested in psychiatry. He moved to Boston in 2002, where he did his psychiatry residency at Boston University and a Master of Public Health at Harvard University. He returned to Brisbane in June 2008 as a clinical academic psychiatrist at the Metro South Addiction and Mental Health Service. He completed his Ph.D in Feb 2014. His research interests include clozapine and treatment refractory schizophrenia, the physical health of people with severe and persistent mental illness, supported accommodation, assertive community treatment and mental health services research. He was awarded an NHMRC Investigator Grant as a Leadership Fellow (L1 2027-2031) an Emerging Leadership Fellow (EL2 2021-2025) and an NHMRC Early Career Fellowship (ECF 2016-2019). He has a current CIA MRFF RCRDUN grant looking at treatments to reduce cardiometabolic morbidity among people with schizophrenia. He was the SIRS 2026 Outstanding Clinical and Community Research Award recipient, and was elected to the Australian Academy of Health and Medical Sciences in 2025. He has over 350 peer reviewed publications, including first author in the highly ranked Lancet, World Psychiatry, Lancet Psychiatry, BJPsych, ANZJP, & Schizophrenia Bulletin. He is a named investigator on over $65 million in competitive research grants, with over $9 million as CIA.

Availability

Professor Dan Siskind is:
Available for supervision
Media expert

Fields of research

Research interests

  • Schizophrenia

  • Physical Health Comorbidity

Research impacts

Prof Siskind's research has had direct, measurable impact on clinical practice and policy. His landmark studies on clozapine-associated neutropenia demonstrated that routine monitoring could safely cease after two years, evidence that has driven the removal of long-term monitoring mandates by regulators — improving safe and quality access to clozapine for more than 2.5 million people globally. His work establishing optimal plasma clozapine reference ranges is now used by pathology providers across Australia, while his findings on antipsychotic-associated metabolic risk and weight gain have been incorporated into international guidelines and adopted into clinical practice, with metformin augmentation now regularly prescribed for patients commencing antipsychotics. His Lancet Psychiatry Commission on physical health in people with mental illness helped set the global agenda for integrating physical and mental healthcare, informing policy from the WHO, OECD, and across multiple countries. As Chair of the INTEGRATE Steering Committee, he led development of the first consensus-based, algorithmic international guidelines for schizophrenia treatment, which have been endorsed by peak bodies. Through sustained engagement with regulators, professional colleges and health services, Prof Siskind has ensured his research translates rapidly from bench to bedside to policy, cementing his reputation as a global leader in schizophrenia care.

Works

Search Professor Dan Siskind’s works on UQ eSpace

468 works between 2007 and 2026

1 - 20 of 468 works

2026

Journal Article

Efficacy and safety outcomes of different plasma clozapine and norclozapine levels in schizophrenia spectrum disorder: a dose-response meta-analysis exploring “critical” levels

Fornaro, Michele, Lorenzo, Chiara Di, Siskind, Dan and de Bartolomeis, Andrea (2026). Efficacy and safety outcomes of different plasma clozapine and norclozapine levels in schizophrenia spectrum disorder: a dose-response meta-analysis exploring “critical” levels. Psychiatry Research, 365 117340, 1-16. doi: 10.1016/j.psychres.2026.117340

Efficacy and safety outcomes of different plasma clozapine and norclozapine levels in schizophrenia spectrum disorder: a dose-response meta-analysis exploring “critical” levels

2026

Journal Article

Prevalence and outcomes of co-occurring psychiatric and endocrine, metabolic, and nutritional disorders: An atlas based on umbrella review of 254,154,533 records

Fornaro, Michele, Di Lorenzo, Chiara, Steardo, Luca, Veronese, Nicola, Stubbs, Brendon, Vancampfort, Davy, Siskind, Dan and Solmi, Marco (2026). Prevalence and outcomes of co-occurring psychiatric and endocrine, metabolic, and nutritional disorders: An atlas based on umbrella review of 254,154,533 records. European Neuropsychopharmacology, 110 112880, 112880-110. doi: 10.1016/j.euroneuro.2026.112880

Prevalence and outcomes of co-occurring psychiatric and endocrine, metabolic, and nutritional disorders: An atlas based on umbrella review of 254,154,533 records

2026

Journal Article

Temporal patterns and risk factors of clozapine-associated neutropenia: a nationwide population-based cohort study

Wu, Chi-Shin, Northwood, Korinne, Wu, Ming-Shiang, Wang, Shi-Heng, Huang, Wei-Lieh, Liu, Chen-Chung and Siskind, Dan (2026). Temporal patterns and risk factors of clozapine-associated neutropenia: a nationwide population-based cohort study. The Lancet Regional Health - Western Pacific, 74 101970, 101970-74. doi: 10.1016/j.lanwpc.2026.101970

Temporal patterns and risk factors of clozapine-associated neutropenia: a nationwide population-based cohort study

2026

Journal Article

Incidence of systemic physical multimorbidity among people with schizophrenia-spectrum or bipolar-spectrum disorders compared with age-matched and sex-matched individuals in Queensland, Australia: a statewide, hospital cohort study

Halstead, Sean, Warren, Nicola, Kisely, Steve, Arnautovska, Urska, Trott, Mike, Correll, Christoph U., Ebdrup, Bjorn H., Heffernan, Ed, Mohr, Grímur Hognason, McCutcheon, Robert A., Morley, Katherine I., O’Donoghue, Brian, Pillinger, Toby, Sara, Grant, Taipale, Heidi and Siskind, Dan (2026). Incidence of systemic physical multimorbidity among people with schizophrenia-spectrum or bipolar-spectrum disorders compared with age-matched and sex-matched individuals in Queensland, Australia: a statewide, hospital cohort study. The Lancet Psychiatry, 13 (9), 771-782. doi: 10.1016/s2215-0366(26)00196-3

Incidence of systemic physical multimorbidity among people with schizophrenia-spectrum or bipolar-spectrum disorders compared with age-matched and sex-matched individuals in Queensland, Australia: a statewide, hospital cohort study

2026

Journal Article

Incidence of clozapine-associated neutropenia in patients with schizophrenia: 20-year population-based study in Hong Kong

Zhou, Huiquan, Luo, Hao, Siskind, Dan, Northwood, Korinne, Tang, Jennifer Yee-Man, Lui, Simon S. Y., Lee, Edwin H. M., Kan, Chui-Kwan, Tsui, Chi Fong, Poon, Lap Tak, Leung, Shuk Yan Joey, Wong, Yip Chau, Wong, Jessica Oi Yin and Chan, Sherry Kit Wa (2026). Incidence of clozapine-associated neutropenia in patients with schizophrenia: 20-year population-based study in Hong Kong. The British Journal of Psychiatry, 1-8. doi: 10.1192/bjp.2026.10726

Incidence of clozapine-associated neutropenia in patients with schizophrenia: 20-year population-based study in Hong Kong

2026

Journal Article

Hospitalisation and mortality outcomes after second COVID-19 vaccination among Australians living with severe mental illness: Findings from a matched case–control study using national data linkage

Bull, Claudia, Wheeler, Amanda J., Palmer, Victoria J., Lewis, Matthew, Siskind, Dan and Kisely, Steve (2026). Hospitalisation and mortality outcomes after second COVID-19 vaccination among Australians living with severe mental illness: Findings from a matched case–control study using national data linkage. Australian and New Zealand Journal of Psychiatry 00048674261475206, 48674261475206-48674261475206. doi: 10.1177/00048674261475206

Hospitalisation and mortality outcomes after second COVID-19 vaccination among Australians living with severe mental illness: Findings from a matched case–control study using national data linkage

2026

Journal Article

Duration of untreated illness in eating disorders: a comprehensive systematic review and meta-regression

de Geus, Gyselle, Trott, Mike, Monteleone, Alessio Maria, Firth, Joseph, Siskind, Dan, Teasdale, Scott, Arnautovska, Urska, Iyer, Ravi, Stubbs, Brendon, Demidenko, Natasha, Martin, David, Antochi, Ruxandra, Fiedorowicz, Jess G., Austin, Amelia, Schmidt, Ulrike, Wade, Tracey, Fernandez-Aranda, Fernando, Herpertz-Dahlmann, Beate, Hoek, Hans W., Voderholzer, Ulrich, Kolar, David, Zipfel, Stephan, Pike, Kathleen M., Karwautz, Andreas, Wonderlich, Stephen, Smith, Lee, Carfagno, Marco and Solmi, Marco (2026). Duration of untreated illness in eating disorders: a comprehensive systematic review and meta-regression. Journal of Eating Disorders. doi: 10.1186/s40337-026-01731-6

Duration of untreated illness in eating disorders: a comprehensive systematic review and meta-regression

2026

Journal Article

The experiences of people diagnosed with severe mental illness and colorectal cancer: a qualitative study

Zirnsak, Tessa-May, De Nicola, Julia, Kisely, Steve, Siskind, Dan, Protani, Melinda M. and Brophy, Lisa (2026). The experiences of people diagnosed with severe mental illness and colorectal cancer: a qualitative study. Australasian Psychiatry, 34 (4), 336-342. doi: 10.1177/10398562251406026

The experiences of people diagnosed with severe mental illness and colorectal cancer: a qualitative study

2026

Journal Article

Management of clozapine-resistant schizophrenia

Lally, John, Gee, Siobhan, Hynes-Ryan, Caroline, Northwood, Korinne, Keating, Dolores, Suetani, Shuichi, Siskind, Dan and O’Donoghue, Brian (2026). Management of clozapine-resistant schizophrenia. Australian and New Zealand Journal of Psychiatry, 48674261462755. doi: 10.1177/00048674261462755

Management of clozapine-resistant schizophrenia

2026

Journal Article

Interventions for smoking cessation in inpatient psychiatry settings

Plever, Sally, Kisely, Steve R, Bonevski, Billie, Siskind, Dan, Yamazaki-Tan, Julia, Thaker, Parth, Vos, Greta, Kim, Doyoon, Guillaumier, Ashleigh and Gartner, Coral E (2026). Interventions for smoking cessation in inpatient psychiatry settings. Cochrane Database of Systematic Reviews, 2026 (7), CD015934. doi: 10.1002/14651858.cd015934.pub2

Interventions for smoking cessation in inpatient psychiatry settings

2026

Journal Article

Reevaluating Clozapine-Induced QT Prolongation

Tanzer, Timothy, Hanisch, Rebecca, Yap, Chloe, Warren, Nicola, Barras, Michael, Kisely, Steve, Isoardi, Katherine, Kosari, Kiana and Siskind, Dan (2026). Reevaluating Clozapine-Induced QT Prolongation. Schizophrenia Bulletin, 52 (4) sbaf114, 1-9. doi: 10.1093/schbul/sbaf114

Reevaluating Clozapine-Induced QT Prolongation

2026

Journal Article

Protocol for the MyPREPED trial: hybrid type 2 effectiveness–implementation trial of a peer-delivered digital self-management tool (MyBRANCHES) for young people in Australia transitioning from early intervention in psychosis services

Milton, Alyssa, Brown, Ellie, Arnautovska, Urska, Vaughan, Priya, Gao, Caroline, Chatterton, Mary Lou, Stratton, Elizabeth, Hancock, Nicola, Chapman, Justin, Iyer, Ravi, Singh, Simran, Malhotra, Saahil, Batara, Sam, Chakma, Symphony, De Cicco, Deanna, Lindsay, Hadley, Harris, Anthony, Siskind, Dan, Warren, Nicola, McHugh, Cate, McArdle, Peter, Phung, Darren, Cook, Jim, Thompson, Andrew and Glozier, Nick (2026). Protocol for the MyPREPED trial: hybrid type 2 effectiveness–implementation trial of a peer-delivered digital self-management tool (MyBRANCHES) for young people in Australia transitioning from early intervention in psychosis services. BJPsych Open, 12 (4) e200, e200. doi: 10.1192/bjo.2026.12056

Protocol for the MyPREPED trial: hybrid type 2 effectiveness–implementation trial of a peer-delivered digital self-management tool (MyBRANCHES) for young people in Australia transitioning from early intervention in psychosis services

2026

Journal Article

Clinical Practice Guideline on the Pharmacological Management of Antipsychotic-Related Dyslipidemia

Carolan, Aoife, Hynes-Ryan, Caroline, Bourke, Rita, Columb, David, Cullen, Walter, deFerranti, Sarah, Harrington, Sophie Mae, Kelleher, Ian, Kennedy, Cormac, Khoury, Michael, Lally, John, Lyne, John, Norton, Michael, O’Connor, Karen, O’Connor, Patricia, O’Shea, Donal, Perry, Benjamin, Prendeville, Terence, Ryan, Cristin, Sadowska, Ewa, Shiers, David, Siskind, Dan, Strawbridge, Judith, Tae, Haeun, Keating, Dolores and O’Donoghue, Brian (2026). Clinical Practice Guideline on the Pharmacological Management of Antipsychotic-Related Dyslipidemia. Schizophrenia Bulletin, 52 (4) sbag086. doi: 10.1093/schbul/sbag086

Clinical Practice Guideline on the Pharmacological Management of Antipsychotic-Related Dyslipidemia

2026

Journal Article

Research priorities for metabolic interventions in severe mental illness: results of a James Lind Alliance Priority Setting Partnership

Farran, Dina, Kapi, Maria, Moffat, Kate, Stratford, Melanie, Solangi, Sadaf, Walsh, Annabel E L, Campbell, Iain, Magee, Caroline, Siskind, Dan, Smith, Daniel, Gaughran, Fiona, Ismail, Khalida, Pillinger, Toby, Agarwal, Mahavir, Ashbrook, David, Berk, Michael, Burgess, Karl, Campbell, Iain, Farran, Dina, Ferguson, Amy, Fleetwood, Kelly, Gaughran, Fiona, Ismail, Khalida, Jackson, Caroline A., Kenney, Joanne P.M., Lightman, Stafford, Luz, Saturnino, Marx, Wolfgang, Oduguwa, Ifeoluwa ... Wyse, Cathy Wyse (2026). Research priorities for metabolic interventions in severe mental illness: results of a James Lind Alliance Priority Setting Partnership. The Lancet Psychiatry, 13 (9), 783-791. doi: 10.1016/s2215-0366(26)00129-x

Research priorities for metabolic interventions in severe mental illness: results of a James Lind Alliance Priority Setting Partnership

2026

Journal Article

Natural disasters and suicidality in Australia: a systematic review

Trott, Mike, Lockett, C., Arnautovska, U., Kisely, S., Crompton, D. and Siskind, D. (2026). Natural disasters and suicidality in Australia: a systematic review. Social Psychiatry and Psychiatric Epidemiology, 1-12. doi: 10.1007/s00127-026-03160-x

Natural disasters and suicidality in Australia: a systematic review

2026

Journal Article

Effects of glucagon-like peptide-1 receptor agonists on anthropometric and adiposity measures in patients with antipsychotic-induced weight gain: a systematic review and meta-analysis

Lee, Songmin, Kim, Min-Gul, Trott, Mike, Siskind, Dan and Kim, Jae Hyun (2026). Effects of glucagon-like peptide-1 receptor agonists on anthropometric and adiposity measures in patients with antipsychotic-induced weight gain: a systematic review and meta-analysis. Journal of Psychopharmacology, 2698811261456190. doi: 10.1177/02698811261456190

Effects of glucagon-like peptide-1 receptor agonists on anthropometric and adiposity measures in patients with antipsychotic-induced weight gain: a systematic review and meta-analysis

2026

Journal Article

Do virtual reality-based therapies affect symptomatology and psychosocial functioning in schizophrenia spectrum disorders: systematic review and meta-analysis

Colgan, George Alexander, Ng, Kelvin Kwok Lap, Siskind, Dan, Trott, Mike and Arnautovska, Urska (2026). Do virtual reality-based therapies affect symptomatology and psychosocial functioning in schizophrenia spectrum disorders: systematic review and meta-analysis. BJPsych Open, 12 (4) e165, e165-e165. doi: 10.1192/bjo.2026.12012

Do virtual reality-based therapies affect symptomatology and psychosocial functioning in schizophrenia spectrum disorders: systematic review and meta-analysis

2026

Journal Article

The feasibility of resistance training versus aerobic exercise in a rehabilitation setting for people living with psychotic disorders: A randomised controlled trial

Korman, Nicole, Stanton, Robert, Trott, Mike, Stubbs, Brendon, Baker, Andrea, Butler, Cassandra, Siskind, Dan, Rosenbaum, Simon, Firth, Joseph, Martland, Rebecca, McIntosh, Talia, Warren, Nicola, Heffernan, Edward, Dark, Frances and Chapman, Justin (2026). The feasibility of resistance training versus aerobic exercise in a rehabilitation setting for people living with psychotic disorders: A randomised controlled trial. Australian and New Zealand Journal of Psychiatry, 60 (6), 538-552. doi: 10.1177/00048674251361681

The feasibility of resistance training versus aerobic exercise in a rehabilitation setting for people living with psychotic disorders: A randomised controlled trial

2026

Journal Article

Stimulant and medicinal cannabis prescribing in patients referred to an early psychosis service in Queensland: a brief report

McArdle, Peter, Trott, Mike, Warren, Nicola, De Silva, Dilprasan, Smith, Lesley, Ritchie, Sarah and Siskind, Dan (2026). Stimulant and medicinal cannabis prescribing in patients referred to an early psychosis service in Queensland: a brief report. Australasian Psychiatry, 34 (3), 253-257. doi: 10.1177/10398562251406048

Stimulant and medicinal cannabis prescribing in patients referred to an early psychosis service in Queensland: a brief report

2026

Journal Article

Effects of Semaglutide on Body Weight in Clozapine-Treated Individuals with Schizophrenia and Obesity: A Randomized Controlled Trial

Siskind, D., Trott, M. and Arnautovska, U. (2026). Effects of Semaglutide on Body Weight in Clozapine-Treated Individuals with Schizophrenia and Obesity: A Randomized Controlled Trial. European Psychiatry, 69 (S1), S110-S110. doi: 10.1192/j.eurpsy.2026.10638

Effects of Semaglutide on Body Weight in Clozapine-Treated Individuals with Schizophrenia and Obesity: A Randomized Controlled Trial

Funding

Current funding

  • 2027
    EVA-DHI: Economic Evaluation Framework for Digital Health Interventions: Stakeholder-Infor med Development and Pilot-Testing
    Queensland Bavaria Collaborative Research Program - Seed Grant
    Open grant
  • 2027 - 2031
    Transforming physical and mental health care for people living with schizophrenia
    NHMRC Investigator Grants
    Open grant
  • 2026
    Sedentary Time Elimination with Periodic activity Snacks (STEPS) study: codesign and evaluation of activity snacks in people with severe mental illness
    Metro South Hospital and Health Service
    Open grant
  • 2025 - 2028
    Randomised controlled trial of screening patients with Schizophrenia for obstructive sleep apnoea using in-laboratory polysomnography or 3-nights of home oximetry (MRFF OSDMOSA led by Macquarie Uni)
    Macquarie University
    Open grant
  • 2025 - 2030
    SYNDICAT: Synergy for the Development of Innovative Clinical Treatments in Schizophrenia (NHMRC 2024 Synergy Grant administered by Deakin University)
    Deakin University
    Open grant
  • 2024 - 2028
    A hybrid-II implementation-effectiveness trial of a peer-supported self-management tool for young people in preparation for early intervention in psychosis service discharge (MY PREP-ED) (Ex USYD)
    Medical Research Futures Fund
    Open grant
  • 2023 - 2028
    Self-care of Multimorbidity in schizophrenia supported by Peer workers: a Co-designed health Information Technology (SiMPlicITy) (externally led NHMRC 2022 Targeted Call administered via Uni of Syd)
    University of Sydney
    Open grant
  • 2023 - 2027
    Using risk profiles to overcome challenges in incorporating polygenic risk scores into clinical mental health practice (QIMR administered MRFF Genomics Health Future Mission grant)
    Queensland Institute of Medical Research
    Open grant
  • 2022 - 2029
    Schizophrenia and Weight Improvement From Tirzepatide (SWIFT)
    NHMRC MRFF - Rare Cancers, Rare Diseases and Unmet Need
    Open grant
  • 2021 - 2027
    Mental Health Australia General Clinical Trial Network (MAGNET) (MRFF Million Minds Mental Health Research Grant Led by Deakin University)
    Deakin University
    Open grant
  • 2020 - 2026
    Helping people with schizophrenia living longer, healthier lives
    Queensland Advancing Clinical Research Fellowship
    Open grant

Past funding

  • 2023 - 2024
    Cannabidiol (CBD) for Clozapine Refractory Schizophrenia (CanCloz)
    University of Sydney
    Open grant
  • 2022 - 2024
    A 40-year life course study of the effects of child maltreatment using linked birth cohort and administrative health data
    Metro South Health Research Support Scheme Project Grant
    Open grant
  • 2021 - 2025
    Reducing the mortality gap for people with schizophrenia
    NHMRC Investigator Grants
    Open grant
  • 2019 - 2025
    What is the impact of the National Bowel Cancer Screening Program on colorectal cancer outcomes for people over the age of 50 with severe mental illness?
    Cancer Council Australia
    Open grant
  • 2019 - 2021
    Identifying and treating patients with psychosis who are positive to anti-neuronal antibodies
    NHMRC Project Grant
    Open grant
  • 2019 - 2022
    Identifying and treating patients with psychosis who are positive to anti-neuronal antibodies (NHMRC Project Grant led by QIMR)
    Queensland Institute of Medical Research
    Open grant
  • 2018 - 2020
    The efficacy of adjunctive metformin to attenuate weight gain and visceral adiposity, and prevent conversion to diabetes in people with schizophrenia newly commenced on clozapine
    Society for Mental Health Research Inc
    Open grant
  • 2018 - 2019
    The efficacy of adjunctive metformin to attenuate weight gain and visceral adiposity, and prevent conversion to diabetes in people with schizophrenia newly commenced on clozapine
    The Australian Diabetes Society
    Open grant
  • 2017 - 2018
    Avant Doctors in Training Research Scholarship Program 2017
    Avant Mutual Group Limited
    Open grant
  • 2017 - 2019
    A comparison study of three physical activity measurement tools examining acceptability in people with psychotic disorders
    Society for Mental Health Research Inc
    Open grant
  • 2017 - 2019
    Acceptability of physical activity measures in people with psychotic disorders
    Royal Australian & New Zealand College Psychiatrists
    Open grant
  • 2016 - 2019
    Cardiometabolic Health of People with Severe and Persistent Mental Illness
    NHMRC Early Career Fellowships
    Open grant
  • 2016 - 2019
    N-Acetyl Cysteine In Schizophrenia Resistant to Clozapine: A Double-Blind Randomised Placebo-Controlled Trial Targeting Negative Symptoms (NHMRC Project grant administed by Uni Melbourne)
    University of Melbourne
    Open grant
  • 2015 - 2017
    Vaporising smoking-related harms in people with severe and persistent mental illness: A study of the acceptability of vaporised nicotine products for smoking cessation or long-term substitution
    Monash University
    Open grant
  • 2015 - 2017
    Quantifying the burden of perinatal depression in Australia and New Zealand
    RANZCP Pat, Toni and Peter Kinsman Research Scholarship
    Open grant
  • 2013 - 2016
    A MAP to better care: Applying the principles of advanced directives and motivational interviewing to discharge planning for psychiatric patients
    Australian Centre for Health Services Innovation
    Open grant

Supervision

Availability

Professor Dan Siskind is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

Contact Professor Dan Siskind directly for media enquiries about:

  • Cardiometabolic co-morbidity of schizophrenia
  • Treatment Refractory Schizophrenia

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