Overview
Background
Doctor James Falconer has been an academic at the School of Pharmacy, The University of Queensland since June 2015. Dr Falconer was an assistant lecturer, then research & teaching fellow at the School of Pharmacy, the University of Auckland from 2011 – 2015.
In 2007 he was awarded with the Technology for Industry Fellowship (TIF) from the New Zealand Foundation for Research, Science & Technology (FRST) from the NZ Government with joint funding from Pharmaceutical Compounding New Zealand (PCNZ) to complete a PhD under A/Professor Jingyuan Wen and Professor Raid Alany from the University of Auckland, New Zealand for development of a supercritical fluid platform and transdermal delivery of poorly aqueous soluble steriods. As a post-doctoral researcher under A/Professor Zimei Wu and collaboration with Argenta Global in Auckland he worked to help stabilise a veterinary pour-on which resulted in international patents and registered product for cattle. He was then appointed as a lecturer in pharmacy practice and pharmaceutical sciences at The University of Queensland in Brisbane, Australia. Prior to his academic career, he received a BSc in Genetics 1999 and a Masters in Health Sciences (Bioethics) in 2003 under A/Professor Neil Pickering on the anatomy of the GMO debate from the University of Otago, Dunedin, New Zealand. In 2005, he completed a BPharm (Hons) from the University of Auckland and undertook an internship at Middlemore Hospital in 2006, then was employed from 2007 as a ward pharmacist in general surgery and the hospital dispensary and as a community pharmacist - including the 'graveyard' shifts at day/night pharmacies.
Doctor Falconer has established research in supercritical fluid applications for selective extraction as well as in engineering advanced nanoparticulate dosage forms based on lipid and polymeric systems. A backbone to this work is the search for green/er technology to replace organic solvent driven material manufacturing processes and the repurposing of carbon dioxide for good.
Availability
- Dr James Robert Falconer is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Science, University of Otago
- Postgraduate Diploma, University of Otago
- Bachelor of Pharmacy, The University of Auckland
- Masters (Research) of Bioethics, University of Otago
- Doctor of Philosophy, The University of Auckland
Research interests
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Primary Research 1: Supercritical fluid technology
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Primary Research 2: Sustainable solvent processing
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SCF preparation of advanced delivery systems such as liposomes and solid lipid nanoparticles
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Selective SCF extraction of principle molecules from indigenous and non-indigenous plants
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Preformulation
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Solid state compounds and dosage forms
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Quantitative analysis using Raman and IR spectroscopy and chemometrics
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Synthesis and characterization of solid state polymorphic transformations
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Spray jet behaviour during SCF rapid exapnsion using in-situ spectroscopy
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Non-linear release modelling such as dual first order
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In-situ gelling systems for systemic and non-systemic drug delivery
Works
Search Professor James Robert Falconer’s works on UQ eSpace
2024
Conference Publication
Green Chemistry Extraction of Psilocybin and Psilocin from Psychedelic Mushrooms Utilising Supercritical Carbon Dioxide
Lanham, Luke, McTaggart, Alistair and Falconer, James R. (2024). Green Chemistry Extraction of Psilocybin and Psilocin from Psychedelic Mushrooms Utilising Supercritical Carbon Dioxide. Controlled Release Society (CRS) Annual Meeting & Exposition, Bologna, Italy, 8-12 July 2024. Bologna, Italy: CRS.
2024
Journal Article
Strategies to improve the transdermal delivery of poorly water-soluble non-steroidal anti-inflammatory drugs
Balmanno, Alexandra, Falconer, James R., Ravuri, Halley G. and Mills, Paul C. (2024). Strategies to improve the transdermal delivery of poorly water-soluble non-steroidal anti-inflammatory drugs. Pharmaceutics, 16 (5) 675, 1-27. doi: 10.3390/pharmaceutics16050675
2023
Conference Publication
A Quick Trip Through Psychedelic Psilocybin
Lanham, Luke, McTaggart, Alistair R. and Falconer, James R. (2023). A Quick Trip Through Psychedelic Psilocybin. Medicines Management, Cairns, QLD, Australia, 2-4 November 2023. SHPA.
2023
Conference Publication
A Brief Tryp Down a Psychedelic Lane
Lanham, Luke, McTaggart, Alistair R. and Falconer, James R. (2023). A Brief Tryp Down a Psychedelic Lane. Toowoomba Hospital Pharmacist Forum, Toowoomba, QLD, Australia, 6 February 2023.
2022
Conference Publication
New developments in psychopharmacotherapy.
Lanham, Luke, McTaggart, Alistair R. and Falconer, James R. (2022). New developments in psychopharmacotherapy.. Medicines Management 2022, Brisbane, QLD, Australia, 1-3 December 2022. SHPA.
2022
Journal Article
Fabrication and Characterization of Clozapine Nanoemulsion Sol–Gel for Intranasal Administration
Tan, Madeleine S. A., Pandey, Preeti, Lohman, Rink-Jan, Falconer, James R., Siskind, Dan J. and Parekh, Harendra S. (2022). Fabrication and Characterization of Clozapine Nanoemulsion Sol–Gel for Intranasal Administration. Molecular Pharmaceutics, 19 (11), 4055-4066. doi: 10.1021/acs.molpharmaceut.2c00513
2022
Conference Publication
Supercritical fluid technology for natural drugs
Falconer, James R. (2022). Supercritical fluid technology for natural drugs. Mushroom' Forum at Forensic and Scientific Services, Brisbane, QLD, Australia, 18 May 2022. FSS conference theatre:
2022
Journal Article
Nanomaterials: the new antimicrobial magic bullet
Ndayishimiye, John, Kumeria, Tushar, Popat, Amirali, Falconer, James Robert and Blaskovich, Mark A. T. (2022). Nanomaterials: the new antimicrobial magic bullet. ACS Infectious Diseases, 8 (4), 693-712. doi: 10.1021/acsinfecdis.1c00660
2022
Journal Article
Niosomal nanocarriers for enhanced dermal delivery of epigallocatechin gallate for protection against oxidative stress of the skin
Li, Danhui, Martini, Nataly, Wu, Zimei, Chen, Shuo, Falconer, James Robert, Locke, Michelle, Zhang, Zhiwen and Wen, Jingyuan (2022). Niosomal nanocarriers for enhanced dermal delivery of epigallocatechin gallate for protection against oxidative stress of the skin. Pharmaceutics, 14 (4) 726, 726. doi: 10.3390/pharmaceutics14040726
2022
Journal Article
Understanding the relationship between solubility and permeability of γ-cyclodextrin-based systems embedded with poorly aqueous soluble benznidazole
Ndayishimiye, John, Kumeria, Tushar, Popat, Amirali, Blaskovich, Mark A.T. and Falconer, James Robert (2022). Understanding the relationship between solubility and permeability of γ-cyclodextrin-based systems embedded with poorly aqueous soluble benznidazole. International Journal of Pharmaceutics, 616 121487, 121487. doi: 10.1016/j.ijpharm.2022.121487
2022
Journal Article
Influence of PEGylated porous silicon nanoparticles on permeation and efflux of an orally administered antibiotic
Raza, A., Kamato, D., Sime, F.B., Roberts, J.A., Popat, A., Falconer, J.R. and Kumeria, T. (2022). Influence of PEGylated porous silicon nanoparticles on permeation and efflux of an orally administered antibiotic. Materials Today Advances, 13 100210, 100210. doi: 10.1016/j.mtadv.2022.100210
2022
Journal Article
Clozapine-encapsulated binary mixed micelles in thermosensitive sol–gels for intranasal administration
Tan, Madeleine S. A., Pandey, Preeti, Falconer, James R., Siskind, Dan J., Balmanno, Alexandra and Parekh, Harendra S. (2022). Clozapine-encapsulated binary mixed micelles in thermosensitive sol–gels for intranasal administration. Gels, 8 (1) 38, 38. doi: 10.3390/gels8010038
2022
Journal Article
Fractional factorial design study for the extraction of cannabinoids from CBD-dominant cannabis flowers by supercritical carbon dioxide
Qamar, Sadia, Torres, Yady J. M., Parekh, Harendra S. and Falconer, James Robert (2022). Fractional factorial design study for the extraction of cannabinoids from CBD-dominant cannabis flowers by supercritical carbon dioxide. Processes, 10 (1) 93, 93. doi: 10.3390/pr10010093
2021
Conference Publication
Thermosensitive nanoemulsion-based Sol-Gel of Clozapine for nose-to-brain delivery
Tan, Madeleine S.A., Pandey, Preeti, Falconer, James R., Siskind, Dan J. and Parekh, Harendra S. (2021). Thermosensitive nanoemulsion-based Sol-Gel of Clozapine for nose-to-brain delivery. Micro and Nanoparticles in Drug and Vaccine Delivery Symposium, Brisbane, QLD Australia, 3 December 2021.
2021
Journal Article
Sustained-release ketamine-loaded lipid-particulate system: in vivo assessment in mice
Xu, Weizhi, Maqbool, Faheem, Kumar, Vinod, Falconer, James R., Cui, Cedric S., Woodruff, Trent M., Borges, Karin, Whittaker, Andrew K., Smith, Maree T. and Han, Felicity Y. (2021). Sustained-release ketamine-loaded lipid-particulate system: in vivo assessment in mice. Drug Delivery and Translational Research, 12 (10), 2518-2526. doi: 10.1007/s13346-021-01093-3
2021
Conference Publication
Nanoemulsion-based sol-gel of Clozapine for nose-to-brain delivery
Tan, Madeleine S. A., Pandey, Preeti, Falconer, James R., Siskind, Dan J. and Parekh, Harendra S. (2021). Nanoemulsion-based sol-gel of Clozapine for nose-to-brain delivery. Drug Delivery Australia Virtual Meeting: Advanced Materials in Drug Delivery, Online, 18 - 19 November 2021.
2021
Journal Article
Effects of ethanol on the supercritical carbon dioxide extraction of cannabinoids from near equimolar (THC and CBD balanced) cannabis flower
Qamar, Sadia, Torres, Yady J. M., Parekh, Harendra S. and Falconer, James Robert (2021). Effects of ethanol on the supercritical carbon dioxide extraction of cannabinoids from near equimolar (THC and CBD balanced) cannabis flower. Separations, 8 (9) 154, 154. doi: 10.3390/separations8090154
2021
Conference Publication
Thermosensitive Micellar Hydrogels of Clozapine for Nose-to-Brain Delivery
Tan, Madeleine SA, Pandey, Preeti, Balmanno, Alexandra, Falconer, James R., Siskind, Dan J. and Parekh, Harendra S. (2021). Thermosensitive Micellar Hydrogels of Clozapine for Nose-to-Brain Delivery. 2021 CRS Virtual Annual Meeting, Mount Laurel, NJ United States, 25-29 July 2021 .
2021
Journal Article
Development and optimization of supercritical fluid extraction setup leading to quantification of 11 cannabinoids derived from medicinal cannabis
Qamar, Sadia, Manrique, Yady J., Parekh, Harendra S. and Falconer, James R. (2021). Development and optimization of supercritical fluid extraction setup leading to quantification of 11 cannabinoids derived from medicinal cannabis. Biology, 10 (6) 481, 1-20. doi: 10.3390/biology10060481
2021
Journal Article
Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery
Raza, Aun, Alavi, Seyed Ebrahim, Sime, Fekade Bruck, Han, Felicity Y., Roberts, Jason A., Popat, Amirali, Falconer, James R. and Kumeria, Tushar (2021). Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery. Acta Biomaterialia, 126, 277-290. doi: 10.1016/j.actbio.2021.03.042
Funding
Past funding
Supervision
Availability
- Dr James Robert Falconer is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Extraction of psilocybin and psilocin from the psilocybe mushroom (Magic Mushroom) utilising a single-pot supercritical carbon dioxide (scCO2) method
Principal Advisor
Other advisors: Associate Professor Peter Moyle
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Doctor Philosophy
The development and optimization of a transdermal firocoxib microemulsion gel for dogs
Associate Advisor
Other advisors: Dr Halley Ravuri, Professor Paul Mills
Completed supervision
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2022
Doctor Philosophy
Advanced Formulation Technologies for Oral Delivery of Antimicrobial Agents
Principal Advisor
Other advisors: Associate Professor Amirali Popat, Professor Mark Blaskovich
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2022
Doctor Philosophy
Nose-to-Brain Delivery of Clozapine in Sol-Gel Systems
Principal Advisor
Other advisors: Professor Dan Siskind, Dr Harendra Parekh
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2022
Doctor Philosophy
Investigation into the selective extraction of cannabinoids from cannabis using supercritical carbon dioxide
Principal Advisor
Other advisors: Dr Harendra Parekh
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2021
Doctor Philosophy
Advanced Oral Antibiotic Formulations
Principal Advisor
Other advisors: Professor Jason Roberts, Professor Peter Cabot, Associate Professor Amirali Popat, Dr Fekade Sime
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2020
Doctor Philosophy
Development of a liposomal platform using green supercritical fluid technology: application towards repurposing and tumour-targeting of albendazole for cancer therapy
Principal Advisor
Other advisors: Associate Professor Peter Moyle
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2019
Doctor Philosophy
Novel extraction and evaluation of papaya leaf for chemotherapeutic molecules
Principal Advisor
Other advisors: Professor Nick Shaw, Associate Professor Marie-Odile Parat
Media
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