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Dr Halley Ravuri
Dr

Halley Ravuri

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Overview

Background

Dr. Halley Ravuri completed his Bachelor of Veterinary Science degree from the Orissa University of Agriculture and Technology, and a Master in Pharmacology and Toxicology from the Birsa Agricultural University, India. He recently finished his PhD in Veterinary Science at UQ in 2022. Before his PhD, he worked as a Research Associate in various research organizations for four years in India. His primary research was focused on developing cancer models for glioma (brain cancer), breast cancer, and melanoma in laboratory rodents, and investigating the efficacy of nano-particulated anticancer compounds. He is very experienced in maintaining, experimenting on laboratory rodents and has hands-on experience in research methodologies including ELISA, PCR, western blot analysis, histopathology, and bioanalytical analysis using HPLC instrumentation

His doctoral research was focused on transdermal drug delivery of nonsteroidal anti-inflammatory drugs (NSAIDs) in veterinary species and evaluating the efficacy of novel transdermal formulations using mass spectrometry-based plasma proteomics and lipidomics. He has garnered tremendous interest and expertise in the use of advanced mass spectrometry instruments including LC-MS/MS, GC-MS, and LC-TOF-MS, for enabling both targeted and discovery analysis of proteins, drugs, and lipid metabolites in animal plasma/serum. He has also worked as a technical assistant at the Analytical Service Unit, School of Agriculture and Food Sciences, UQ, using mass spectrometry for the analysis of pesticides, and fatty acid composition in milk, soils, and food samples.

Dr. Halley Ravuri is working at The School of Biomedical Sciences, Faculty of Medicine, UQ – as a Postdoctoral Research Fellow, under the supervision of Prof. Mark Midwinter. His current research goals are to characterize endothelial glycocalyx metabolites in serum/plasma using advanced mass spectrometry techniques, and also explore the pathophysiology of trauma and hemorrhagic shock using a proteomics-based approach. He also has a keen interest in exploring alternative in-vitro techniques to investigate endothelial glycocalyx, and examining the role of exosomes in trauma/hemorrhagic shock in animals and humans. His long-term goal is to establish himself as a translational proteomics expert in the field of plasma biomarker discovery and establish novel mass spectrometry methods and data analysis pipelines to improve the application of mass spectrometry research in the veterinary and translation biomedical sciences. He is an advocate of the use of mass spectrometry-based proteomics to contribute to the field of “One Health”; using veterinary species as translational models for studying human diseases. His future research goals include exploring viral proteomics to investigate and understand the virulence of viruses, characterise viral antibodies using mass spectrometry and studying physiological responses in animals, humans, and model organisms.

Availability

Dr Halley Ravuri is:
Available for supervision

Qualifications

  • Bachelor of Veterinary Sciences, Orissa University of Agriculture and Technology
  • Masters (Research) of Veterinary Pharmacology, Birsa Agricultural University
  • Doctor of Philosophy of Veterinary Science, The University of Queensland

Research interests

  • Mass spectrometry-based plasma proteomics, especially DIA mass spectrometry

  • Mass spectrometry-based plasma metabolomic and lipidomic analysis

  • In-vitro characterisation of endothelial cell-lines for studying role of glycocalyx

  • Investigating role of extracellular vesicles in metabolic and inflammatory diseases in both human and animals

Works

Search Professor Halley Ravuri’s works on UQ eSpace

28 works between 2013 and 2025

1 - 20 of 28 works

2025

Journal Article

Efficacy of transdermal ketoprofen on surgical inflammation in dogs

Ravuri, H.G., Sadowski, P., Satake, N. and Mills, P.C. (2025). Efficacy of transdermal ketoprofen on surgical inflammation in dogs. Research in Veterinary Science, 183 105512, 105512. doi: 10.1016/j.rvsc.2024.105512

Efficacy of transdermal ketoprofen on surgical inflammation in dogs

2024

Journal Article

Strategies to improve the transdermal delivery of poorly water-soluble non-steroidal anti-inflammatory drugs

Balmanno, Alexandra, Falconer, James R., Ravuri, Halley G. and Mills, Paul C. (2024). Strategies to improve the transdermal delivery of poorly water-soluble non-steroidal anti-inflammatory drugs. Pharmaceutics, 16 (5) 675, 1-27. doi: 10.3390/pharmaceutics16050675

Strategies to improve the transdermal delivery of poorly water-soluble non-steroidal anti-inflammatory drugs

2023

Conference Publication

Proteomics to test the efficacy of novel transdermal NSAIDs

Mills, P. C., Ravuri, H. G. and Sadowsk, P. (2023). Proteomics to test the efficacy of novel transdermal NSAIDs. 15th International Congress of the European Association for Veterinary Pharmacology and Toxicology, Bruges, Belgium, 2–5 July 2023. Hoboken, NJ, United States: Wiley. doi: 10.1111/jvp.13272

Proteomics to test the efficacy of novel transdermal NSAIDs

2022

Journal Article

Plasma proteomic changes in response to surgical trauma and a novel transdermal analgesic treatment in dogs

Ravuri, Halley Gora, Sadowski, Pawel, Noor, Zainab, Satake, Nana and Mills, Paul C (2022). Plasma proteomic changes in response to surgical trauma and a novel transdermal analgesic treatment in dogs. Journal of Proteomics, 265 104648, 104648. doi: 10.1016/j.jprot.2022.104648

Plasma proteomic changes in response to surgical trauma and a novel transdermal analgesic treatment in dogs

2022

Other Outputs

Efficacy of transdermally delivered non-steroidal anti-inflammatory drugs (NSAID’s) in dogs

Ravuri, Halley Gora (2022). Efficacy of transdermally delivered non-steroidal anti-inflammatory drugs (NSAID’s) in dogs. PhD Thesis, School of Veterinary Science, The University of Queensland. doi: 10.14264/6a57fbf

Efficacy of transdermally delivered non-steroidal anti-inflammatory drugs (NSAID’s) in dogs

2022

Journal Article

Pharmacokinetic evaluation of a novel transdermal ketoprofen formulation in healthy dogs

Ravuri, Halley Gora, Satake, Nana, Balmanno, Alexandra, Skinner, Jazmine, Kempster, Samantha and Mills, Paul C. (2022). Pharmacokinetic evaluation of a novel transdermal ketoprofen formulation in healthy dogs. Pharmaceutics, 14 (3) 646, 646. doi: 10.3390/pharmaceutics14030646

Pharmacokinetic evaluation of a novel transdermal ketoprofen formulation in healthy dogs

2022

Journal Article

Data-independent acquisition enables robust quantification of 400 proteins in non-depleted canine plasma

Ravuri, Halley Gora, Noor, Zainab, Mills, Paul C., Satake, Nana and Sadowski, Pawel (2022). Data-independent acquisition enables robust quantification of 400 proteins in non-depleted canine plasma. Proteomes, 10 (1) 9, 9. doi: 10.3390/proteomes10010009

Data-independent acquisition enables robust quantification of 400 proteins in non-depleted canine plasma

2021

Journal Article

Correction: The unintended mitochondrial uncoupling effects of the FDA-approved anti-helminth drug nitazoxanide mitigates experimental parkinsonism in mice

Amireddy, Niharika, Puttapaka, Srinivas N., Vinnakota, Ravali L., Ravuri, Halley G., Thonda, Swaroop and Kalivendi, Shasi V. (2021). Correction: The unintended mitochondrial uncoupling effects of the FDA-approved anti-helminth drug nitazoxanide mitigates experimental parkinsonism in mice. Journal of Biological Chemistry, 297 (1) 100864, 1-1. doi: 10.1016/j.jbc.2021.100864

Correction: The unintended mitochondrial uncoupling effects of the FDA-approved anti-helminth drug nitazoxanide mitigates experimental parkinsonism in mice

2019

Conference Publication

Comprehensive dog plasma spectral libraries for SWATH-MS data acquisition

Ravuri, Halley, Satake, Nana, Mills, Paul C. and Sadowski, Pawel (2019). Comprehensive dog plasma spectral libraries for SWATH-MS data acquisition. Human Proteome Organisation World Congress (HUPO), Adelaide, SA Australia, 15-18 September 2019.

Comprehensive dog plasma spectral libraries for SWATH-MS data acquisition

2019

Journal Article

Dual targeting of folate receptor-expressing glioma tumor-associated macrophages and epithelial cells in the brain using a carbon nanosphere-cationic folate nanoconjugate

Elechalawar, Chandra Kumar, Bhattacharya, Dwaipayan, Ahmed, Mohammed Tanveer, Gora, Halley, Sridharan, Kathyayani, Chaturbedy, Piyush, Sinha, Sarmistha Halder, Chandra Sekhar Jaggarapu, Madhan Mohan, Narayan, Kumar Pranav, Chakravarty, Sumana, Eswaramoorthy, Muthusamy, Kundu, Tapas Kumar and Banerjee, Rajkumar (2019). Dual targeting of folate receptor-expressing glioma tumor-associated macrophages and epithelial cells in the brain using a carbon nanosphere-cationic folate nanoconjugate. Nanoscale Advances, 1 (9), 3555-3567. doi: 10.1039/c9na00056a

Dual targeting of folate receptor-expressing glioma tumor-associated macrophages and epithelial cells in the brain using a carbon nanosphere-cationic folate nanoconjugate

2018

Conference Publication

Generation of dog spectral library for plasma proteins: using SWATH-MS technique

Ravuri, Halley Gora, Satake, Nana, Sadowski, Pawel and Mills, Paul C. (2018). Generation of dog spectral library for plasma proteins: using SWATH-MS technique. 3rd Queensland Mass Spectrometry Conference, Brisbane, QLD Australia, 6-7 December 2018.

Generation of dog spectral library for plasma proteins: using SWATH-MS technique

2018

Journal Article

Design of multifunctional peptide collaborated and docetaxel loaded lipid nanoparticles for antiglioma therapy

Kadari, Amrita, Pooja, Deep, Gora, Ravuri Halley, Gudem, Sagarika, Kolapalli, Venkata Ramana Murthy, Kulhari, Hitesh and Sistla, Ramakrishna (2018). Design of multifunctional peptide collaborated and docetaxel loaded lipid nanoparticles for antiglioma therapy. European Journal of Pharmaceutics and Biopharmaceutics, 132, 168-179. doi: 10.1016/j.ejpb.2018.09.012

Design of multifunctional peptide collaborated and docetaxel loaded lipid nanoparticles for antiglioma therapy

2018

Journal Article

Supplementation of oat (Avena sativa L.) extract abates alcohol-induced acute liver injury in a mouse model

Mir, Salma Mukhtar, Sahu, Bidya Dhar, Koneru, Meghana, Kuncha, Madhusudana, Jerald, Mahesh Kumar, Ravuri, Halley Gora, Kanjilal, Sanjit and Sistla, Ramakrishna (2018). Supplementation of oat (Avena sativa L.) extract abates alcohol-induced acute liver injury in a mouse model. Nutrition Research, 54, 80-92. doi: 10.1016/j.nutres.2018.04.002

Supplementation of oat (Avena sativa L.) extract abates alcohol-induced acute liver injury in a mouse model

2018

Journal Article

Ferulic acid protects lipopolysaccharide-induced acute kidney injury by suppressing inflammatory events and upregulating antioxidant defenses in Balb/c mice

Mir, Salma Mukhtar, Ravuri, Halley Gora, Pradhan, Raj Kumar, Narra, Sairam, Kumar, Jerald Mahesh, Kuncha, Madhusudana, Kanjilal, Sanjit and Sistla, Ramakrishna (2018). Ferulic acid protects lipopolysaccharide-induced acute kidney injury by suppressing inflammatory events and upregulating antioxidant defenses in Balb/c mice. Biomedicine and Pharmacotherapy, 100, 304-315. doi: 10.1016/j.biopha.2018.01.169

Ferulic acid protects lipopolysaccharide-induced acute kidney injury by suppressing inflammatory events and upregulating antioxidant defenses in Balb/c mice

2018

Journal Article

Fabrication of surfactant-stabilized nanosuspension of naringenin to surpass its poor physiochemical properties and low oral bioavailability

Singh, Mayank Kumar, Pooja, Deep, Ravuri, Halley Gora, Gunukula, Anusha, Kulhari, Hitesh and Sistla, Ramakrishna (2018). Fabrication of surfactant-stabilized nanosuspension of naringenin to surpass its poor physiochemical properties and low oral bioavailability. Phytomedicine, 40, 48-54. doi: 10.1016/j.phymed.2017.12.021

Fabrication of surfactant-stabilized nanosuspension of naringenin to surpass its poor physiochemical properties and low oral bioavailability

2018

Journal Article

Oestrogen receptor-mediated liposomal drug delivery for treating melanoma

Ganguly, Anirban, Rachamalla, Hari Krishna Reddy, Bhattacharya, Dwaipayan, Bhamidipati, Keerti, Pal, Abhishek, Ravuri, Halley Gora, Chakravarty, Sumana, Adhikari, Susanta Sekhar and Banerjee, Rajkumar (2018). Oestrogen receptor-mediated liposomal drug delivery for treating melanoma. Journal of Drug Targeting, 26 (5-6), 481-493. doi: 10.1080/1061186x.2018.1433679

Oestrogen receptor-mediated liposomal drug delivery for treating melanoma

2017

Journal Article

Capsaicin, the pungent principle of peppers, ameliorates alcohol-induced acute liver injury in mice via modulation of matrix metalloproteinases

Koneru, Meghana, Sahu, Bidya Dhar, Mir, Salma Mukhtar, Ravuri, Halley Gora, Kuncha, Madhusudana, Kumar, Jerald Mahesh, Kilari, Eswar Kumar and Sistla, Ramakrishna (2017). Capsaicin, the pungent principle of peppers, ameliorates alcohol-induced acute liver injury in mice via modulation of matrix metalloproteinases. Canadian Journal of Physiology and Pharmacology, 96 (4), 419-427. doi: 10.1139/cjpp-2017-0473

Capsaicin, the pungent principle of peppers, ameliorates alcohol-induced acute liver injury in mice via modulation of matrix metalloproteinases

2017

Journal Article

Large Amino Acid Transporter 1 Selective Liposomes of l-DOPA Functionalized Amphiphile for Combating Glioblastoma

Bhunia, Sukanya, Vangala, Venugopal, Bhattacharya, Dwaipayan, Ravuri, Halley Gora, Kuncha, Madhusudana, Chakravarty, Sumana, Sistla, Ramakrishna and Chaudhuri, Arabinda (2017). Large Amino Acid Transporter 1 Selective Liposomes of l-DOPA Functionalized Amphiphile for Combating Glioblastoma. Molecular Pharmaceutics, 14 (11), 3834-3847. doi: 10.1021/acs.molpharmaceut.7b00569

Large Amino Acid Transporter 1 Selective Liposomes of l-DOPA Functionalized Amphiphile for Combating Glioblastoma

2017

Journal Article

Polydatin alleviates alcohol-induced acute liver injury in mice: Relevance of matrix metalloproteinases (MMPs) and hepatic antioxidants

Koneru, Meghana, Sahu, Bidya Dhar, Gudem, Sagarika, Kuncha, Madhusudana, Ravuri, Halley Gora, Kumar, Jerald Mahesh, Kilari, Eswar Kumar and Sistla, Ramakrishna (2017). Polydatin alleviates alcohol-induced acute liver injury in mice: Relevance of matrix metalloproteinases (MMPs) and hepatic antioxidants. Phytomedicine, 27, 23-32. doi: 10.1016/j.phymed.2017.01.013

Polydatin alleviates alcohol-induced acute liver injury in mice: Relevance of matrix metalloproteinases (MMPs) and hepatic antioxidants

2015

Journal Article

Bacteriological analysis of drinking water from different sources in and around Ranchi, Jharkhand

Kerketta, Priscilla, Gora, Ravuri Halley, Baxla, Sushma Lalita, Kumari, Suruchi and Yadava, Rajendra (2015). Bacteriological analysis of drinking water from different sources in and around Ranchi, Jharkhand. Journal of Pure and Applied Microbiology, 9 (Special Edition), 327-332.

Bacteriological analysis of drinking water from different sources in and around Ranchi, Jharkhand

Funding

Current funding

  • 2024 - 2025
    Role of plasma extracellular vesicles in equine metabolic syndrome (EMS) condition
    Research Donation Generic
    Open grant

Past funding

  • 2022 - 2024
    Determination of proteomic and lipidomic profiles of horses with Equine Metabolic Syndrome and hyperinsulinemia-associated laminitis
    Boehringer Ingelheim Vetmedica GmbH
    Open grant
  • 2021 - 2023
    Proteomic profiling for culicoides induced hypersensitivity in horses
    Boehringer Ingelheim Vetmedica GmbH
    Open grant
  • 2020 - 2022
    Mass spectrometry based blood plasma prostanoids quantification in dogs
    Canine Research Foundation
    Open grant
  • 2018 - 2020
    Development of novel transdermal analgesic (NSAIDs) formulations in dogs
    John & Mary Kibble Trust
    Open grant

Supervision

Availability

Dr Halley Ravuri is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

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