Overview
Background
Doctor James Falconer has been an academic at the School of Pharmacy, The University of Queensland since June 2015. Dr Falconer was an assistant lecturer, then research & teaching fellow at the School of Pharmacy, the University of Auckland from 2011 – 2015.
In 2007 he was awarded with the Technology for Industry Fellowship (TIF) from the New Zealand Foundation for Research, Science & Technology (FRST) from the NZ Government with joint funding from Pharmaceutical Compounding New Zealand (PCNZ) to complete a PhD under A/Professor Jingyuan Wen and Professor Raid Alany from the University of Auckland, New Zealand for development of a supercritical fluid platform and transdermal delivery of poorly aqueous soluble steriods. As a post-doctoral researcher under A/Professor Zimei Wu and collaboration with Argenta Global in Auckland he worked to help stabilise a veterinary pour-on which resulted in international patents and registered product for cattle. He was then appointed as a lecturer in pharmacy practice and pharmaceutical sciences at The University of Queensland in Brisbane, Australia. Prior to his academic career, he received a BSc in Genetics 1999 and a Masters in Health Sciences (Bioethics) in 2003 under A/Professor Neil Pickering on the anatomy of the GMO debate from the University of Otago, Dunedin, New Zealand. In 2005, he completed a BPharm (Hons) from the University of Auckland and undertook an internship at Middlemore Hospital in 2006, then was employed from 2007 as a ward pharmacist in general surgery and the hospital dispensary and as a community pharmacist - including the 'graveyard' shifts at day/night pharmacies.
Doctor Falconer has established research in supercritical fluid applications for selective extraction as well as in engineering advanced nanoparticulate dosage forms based on lipid and polymeric systems. A backbone to this work is the search for green/er technology to replace organic solvent driven material manufacturing processes and the repurposing of carbon dioxide for good.
Availability
- Dr James Robert Falconer is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Science, University of Otago
- Postgraduate Diploma, University of Otago
- Bachelor of Pharmacy, The University of Auckland
- Masters (Research) of Bioethics, University of Otago
- Doctor of Philosophy, The University of Auckland
Research interests
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Primary Research 1: Supercritical fluid technology
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Primary Research 2: Sustainable solvent processing
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SCF preparation of advanced delivery systems such as liposomes and solid lipid nanoparticles
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Selective SCF extraction of principle molecules from indigenous and non-indigenous plants
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Preformulation
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Solid state compounds and dosage forms
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Quantitative analysis using Raman and IR spectroscopy and chemometrics
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Synthesis and characterization of solid state polymorphic transformations
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Spray jet behaviour during SCF rapid exapnsion using in-situ spectroscopy
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Non-linear release modelling such as dual first order
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In-situ gelling systems for systemic and non-systemic drug delivery
Works
Search Professor James Robert Falconer’s works on UQ eSpace
2019
Journal Article
Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing
Maqbool, Faheem, Moyle, Peter M., Tan, Madeleine S. A., Thurecht, Kristofer J. and Falconer, James R. (2019). Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing. Artificial Cells, Nanomedicine, and Biotechnology, 46 (sup3), 1-7. doi: 10.1080/21691401.2018.1536059
2019
Journal Article
Solid nanoparticles for oral antimicrobial drug delivery: a review
Raza, Aun, Sime, Fekade Bruck, Cabot, Peter J., Maqbool, Faheem, Roberts, Jason A. and Falconer, James Robert (2019). Solid nanoparticles for oral antimicrobial drug delivery: a review. Drug Discovery Today, 24 (3), 858-866. doi: 10.1016/j.drudis.2019.01.004
2019
Conference Publication
Production of liposomes using supercritical fluid technology and active targeting peptide to a gastrointestinal receptor in cancer cells
Maqbool, Faheem, Moyle, Peter M. and Falconer, James R. (2019). Production of liposomes using supercritical fluid technology and active targeting peptide to a gastrointestinal receptor in cancer cells. Controlled Release Society (CRS), Valencia, Spain, 21-24 July 2019.
2019
Conference Publication
The solvent power of supercritical carbon dioxide technology
Falconer, James R. (2019). The solvent power of supercritical carbon dioxide technology. Drug Delivery Australia (DDA), Brisbane, Australia, 18-19 November 2019.
2019
Other Outputs
HaBS-Med Collaborative Seeding Grants 2019
Han, Felicity, Kumeria, Tushar and Falconer, James R. (2019). HaBS-Med Collaborative Seeding Grants 2019. The University of Queensland. (Dataset) doi: 10.14264/uql.2019.756
2018
Conference Publication
Preparation of proliposomes using supercritical fluid
Tan, Madeleine, Maqbool, Faheem and Falconer, James (2018). Preparation of proliposomes using supercritical fluid. Pharmaceutical Society of Australia 2018, Sydney, Australia, 27-29 July 2018.
2018
Conference Publication
Novel preparation of proliposomes with various phospholipids in Supercritical Carbon Dioxide
Maqbool, Faheem, Moyle, Peter M. and Falconer, James R. (2018). Novel preparation of proliposomes with various phospholipids in Supercritical Carbon Dioxide. Controlled Release Society (CRS), New York City, United States, 22-25 July 2018.
2017
Journal Article
Solvent supercritical fluid technologies to extract bioactive compounds from natural sources: a review
Khaw, Kooi-Yeong, Parat, Marie-Odile, Shaw, Paul Nicholas and Falconer, James Robert (2017). Solvent supercritical fluid technologies to extract bioactive compounds from natural sources: a review. Molecules, 22 (7) 1186, 1186. doi: 10.3390/molecules22071186
2017
Journal Article
Erratum: Extemporaneously compounded medicines (vol 40, pg 5, 2017)
Falconer, James R. and Steadman, Kathryn J. (2017). Erratum: Extemporaneously compounded medicines (vol 40, pg 5, 2017). Australian Prescriber, 40 (3), 119-119. doi: 10.18773/austprescr.2017.042
2017
Journal Article
Extemporaneously compounded medicines
Falconer , James R. and Steadman, Kathryn J. (2017). Extemporaneously compounded medicines. Australian Prescriber, 40 (1), 5-8. doi: 10.18773/austprescr.2017.001
2017
Conference Publication
Screening of parameters affecting supercritical CO2 extraction of freeze-dried leaf juice of Carica papaya
Khaw, Kooi Yeong, Parat, Marie-Odile, Shaw, Paul N. and Falconer, James R. (2017). Screening of parameters affecting supercritical CO2 extraction of freeze-dried leaf juice of Carica papaya. Drug Delivery Australia (DDA), Wollongong, NSW Australia, 23-24 October 2017.
2017
Conference Publication
A static and gravimetric method for the determination of solubility of Albendazole and its characterization in supercritical carbon dioxide
Maqbool, Faheem, Moyle, Peter M. and Falconer, James R. (2017). A static and gravimetric method for the determination of solubility of Albendazole and its characterization in supercritical carbon dioxide. Drug Delivery Australia (DDA), Wollongong, Australia, 23-24 October 2017.
2016
Journal Article
Improving drug retention in liposomes by aging with the aid of glucose.
Zhang, Wenli, Falconer, James R., Baguley, Bruce C., Shaw, John P., Kanamala, Manju, Xu, Hongtao, Wang, Guangji, Liu, Jianping and Wu, Zimei (2016). Improving drug retention in liposomes by aging with the aid of glucose.. International Journal of Pharmaceutics, 505 (1-2), 194-203. doi: 10.1016/j.ijpharm.2016.03.044
2016
Other Outputs
Transdermal formulations
Batt, Laurie Robert, Win, Su, Davies, Keryn, Gill, David Anthony, Falconer, James Robert, Cleverly, Douglas Robert and Wu, Zimei (2016). Transdermal formulations. WO 2014132227 A1.
2015
Journal Article
Supercritical fluid technologies to fabricate proliposomes
Falconer, James R., Svirskis, Darren, Adil, Ali A. and Wu, Zimei (2015). Supercritical fluid technologies to fabricate proliposomes. Journal of Pharmacy and Pharmaceutical Sciences, 18 (5), 747-764. doi: 10.18433/j3qp58
2015
Journal Article
Strategies to maximize liposomal drug loading for a poorly water-soluble anticancer drug
Zhang, Wenli, Wang, Guangji, Falconer, James R., Baguley, Bruce C., Shaw, John P., Liu, Jianping, Xu, Hongtao, See, Esther, Sun, Jianguo, Aa, Jiye and Wu, Zimei (2015). Strategies to maximize liposomal drug loading for a poorly water-soluble anticancer drug. Pharmaceutical Research, 32 (4), 1451-1461. doi: 10.1007/s11095-014-1551-8
2014
Journal Article
An investigation into the stability and sterility of citric acid solutions used for cough reflex testing
Falconer, James R., Wu, Zimei, Lau, Hugo, Suen, Joanna, Wang, Lucy, Pottinger, Sarah, Lee, Elaine, Alazawi, Nawar, Kallesen, Molly, Gargiulo, Derryn A., Swift, Simon and Svirskis, Darren (2014). An investigation into the stability and sterility of citric acid solutions used for cough reflex testing. Dysphagia, 29 (5), 622-628. doi: 10.1007/s00455-014-9558-1
2014
Journal Article
A study of microemulsions as prolonged-release injectables through in-situ phase transition
Wu, Zimei, Alany, Raid G., Tawfeek, Noor, Falconer, James, Zhang, Wenli, Hassan, Ibrahim M., Rutland, Michael and Svirskis, Darren (2014). A study of microemulsions as prolonged-release injectables through in-situ phase transition. Journal of Controlled Release, 174 (1), 188-194. doi: 10.1016/j.jconrel.2013.11.022
2014
Conference Publication
Study of phase-transitioning microemulsions for sustained-release dermal/transdermal drug delivery
Falconer, James R., Eng, P.L., Huang, Y., Nasef, N., Nguyen, I., Song, Y., Wu, Zimei and Darren M Sirvirkis (2014). Study of phase-transitioning microemulsions for sustained-release dermal/transdermal drug delivery. HealtheX, Auckland, New Zealand, 18 September 2014.
2014
Journal Article
Evaluation of progesterone permeability from supercritical fluid processed dispersion systems
Falconer, James R., Wen, Jingyuan, Zargar-Shoshtari, Sara, Chen, John J., Farid, Mohammed, El Maghraby, Gamal M. and Alany, Raid G. (2014). Evaluation of progesterone permeability from supercritical fluid processed dispersion systems. Pharmaceutical Development and Technology, 19 (2), 238-246. doi: 10.3109/10837450.2013.769570
Funding
Past funding
Supervision
Availability
- Dr James Robert Falconer is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Extraction of psilocybin and psilocin from the psilocybe mushroom (Magic Mushroom) utilising a single-pot supercritical carbon dioxide (scCO2) method
Principal Advisor
Other advisors: Associate Professor Peter Moyle
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Doctor Philosophy
Extraction of bioactives from natural resources using supercritical fluid technology and their activity testing for the pharmaceutical and food industry
Principal Advisor
Other advisors: Associate Professor Marie-Odile Parat
Completed supervision
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2022
Doctor Philosophy
Advanced Formulation Technologies for Oral Delivery of Antimicrobial Agents
Principal Advisor
Other advisors: Professor Amirali Popat, Professor Mark Blaskovich
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2022
Doctor Philosophy
Nose-to-Brain Delivery of Clozapine in Sol-Gel Systems
Principal Advisor
Other advisors: Professor Dan Siskind, Dr Harendra Parekh
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2022
Doctor Philosophy
Investigation into the selective extraction of cannabinoids from cannabis using supercritical carbon dioxide
Principal Advisor
Other advisors: Dr Harendra Parekh
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2021
Doctor Philosophy
Advanced Oral Antibiotic Formulations
Principal Advisor
Other advisors: Professor Jason Roberts, Professor Peter Cabot, Professor Amirali Popat, Dr Fekade Sime
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2020
Doctor Philosophy
Development of a liposomal platform using green supercritical fluid technology: application towards repurposing and tumour-targeting of albendazole for cancer therapy
Principal Advisor
Other advisors: Associate Professor Peter Moyle
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2019
Doctor Philosophy
Novel extraction and evaluation of papaya leaf for chemotherapeutic molecules
Principal Advisor
Other advisors: Professor Nick Shaw, Associate Professor Marie-Odile Parat
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2024
Doctor Philosophy
The development and optimization of a transdermal firocoxib microemulsion gel for dogs
Associate Advisor
Other advisors: Dr Halley Ravuri, Professor Paul Mills
Media
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