Overview
Background
Doctor James Falconer has been an academic at the School of Pharmacy, The University of Queensland since June 2015. Dr Falconer was an assistant lecturer, then research & teaching fellow at the School of Pharmacy, the University of Auckland from 2011 – 2015.
In 2007 he was awarded with the Technology for Industry Fellowship (TIF) from the New Zealand Foundation for Research, Science & Technology (FRST) from the NZ Government with joint funding from Pharmaceutical Compounding New Zealand (PCNZ) to complete a PhD under A/Professor Jingyuan Wen and Professor Raid Alany from the University of Auckland, New Zealand for development of a supercritical fluid platform and transdermal delivery of poorly aqueous soluble steriods. As a post-doctoral researcher under A/Professor Zimei Wu and collaboration with Argenta Global in Auckland he worked to help stabilise a veterinary pour-on which resulted in international patents and registered product for cattle. He was then appointed as a lecturer in pharmacy practice and pharmaceutical sciences at The University of Queensland in Brisbane, Australia. Prior to his academic career, he received a BSc in Genetics 1999 and a Masters in Health Sciences (Bioethics) in 2003 under A/Professor Neil Pickering on the anatomy of the GMO debate from the University of Otago, Dunedin, New Zealand. In 2005, he completed a BPharm (Hons) from the University of Auckland and undertook an internship at Middlemore Hospital in 2006, then was employed from 2007 as a ward pharmacist in general surgery and the hospital dispensary and as a community pharmacist - including the 'graveyard' shifts at day/night pharmacies.
Doctor Falconer has established research in supercritical fluid applications for selective extraction as well as in engineering advanced nanoparticulate dosage forms based on lipid and polymeric systems. A backbone to this work is the search for green/er technology to replace organic solvent driven material manufacturing processes and the repurposing of carbon dioxide for good.
Availability
- Dr James Robert Falconer is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Science, University of Otago
- Postgraduate Diploma, University of Otago
- Bachelor of Pharmacy, The University of Auckland
- Masters (Research) of Bioethics, University of Otago
- Doctor of Philosophy, The University of Auckland
Research interests
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Primary Research 1: Supercritical fluid technology
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Primary Research 2: Sustainable solvent processing
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SCF preparation of advanced delivery systems such as liposomes and solid lipid nanoparticles
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Selective SCF extraction of principle molecules from indigenous and non-indigenous plants
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Preformulation
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Solid state compounds and dosage forms
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Quantitative analysis using Raman and IR spectroscopy and chemometrics
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Synthesis and characterization of solid state polymorphic transformations
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Spray jet behaviour during SCF rapid exapnsion using in-situ spectroscopy
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Non-linear release modelling such as dual first order
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In-situ gelling systems for systemic and non-systemic drug delivery
Works
Search Professor James Robert Falconer’s works on UQ eSpace
2014
Journal Article
Preparation and characterization of progesterone dispersions using supercritical carbon dioxide
Falconer, James R., Wen, Jingyuan, Zargar-Shoshtari, Sara, Chen, John J., Farid, Mohammed, Tallon, Stephen J. and Alany, Raid G. (2014). Preparation and characterization of progesterone dispersions using supercritical carbon dioxide. Drug Development and Industrial Pharmacy, 40 (4), 458-469. doi: 10.3109/03639045.2013.768630
2013
Conference Publication
Permeability and stability of dispersion systems in the presence of penetration enhancers
Falconer, James R. , Wen, Jingyuan , Zargar-Shoshtari, Sara , Chen, John J. , Farid, Mohammed , El Maghraby, Gamal M. and Alany, Raid G. (2013). Permeability and stability of dispersion systems in the presence of penetration enhancers. Controlled Release Society (CRS), Hawaii, United States, 21-24 July 2013.
2013
Conference Publication
Supercritical Fluids - what are they? A case for delivery of brick dust bioactives
Falconer, James R. , Wen, Jingyuan , Zargar-Shoshtari, Sara , Chen, John J. , Farid, Mohammed , Tallon, Steven J. and Alany, Raid (2013). Supercritical Fluids - what are they? A case for delivery of brick dust bioactives. Found in Translation - Formulation and Delivery of Bioactives (FDB), Dunedin, New Zealand, 13 - 14 February 2013. Otago, New Zealand: School of Pharmacy, University of Otago.
2013
Journal Article
Effects of supercritical carbon dioxide processing on optical crystallinity and in vitro release of progesterone and Gelucire 44/14 solid and semi-solid dispersions
Falconer, J. R., Wen, J., Zargar-Shoshtari, S., Chen, J. J., Farid, M., Young, S. and Alany, R. G. (2013). Effects of supercritical carbon dioxide processing on optical crystallinity and in vitro release of progesterone and Gelucire 44/14 solid and semi-solid dispersions. Journal of Drug Delivery Science and Technology, 23 (5), 477-483. doi: 10.1016/S1773-2247(13)50069-4
2013
Conference Publication
Development and validation of an efficient HPLC method for quantitative analysis of Coenzyme Q10
Huang, I., Abdulqadir, A., Lee, E., Choi, J., Kim, J. and Falconer, James R. (2013). Development and validation of an efficient HPLC method for quantitative analysis of Coenzyme Q10. HealtheX, Auckland, New Zealand, 15 September 2013.
2012
Journal Article
The effects of supercritical carbon dioxide processing on progesterone dispersion systems: a multivariate study
Falconer, James R., Wen, Jingyuan, Zargar-Shoshtari, Sara, Chen, John J., Mohammed, Farid, Chan, Judy and Alany, Raid G. (2012). The effects of supercritical carbon dioxide processing on progesterone dispersion systems: a multivariate study. AAPS PharmSciTech, 13 (4), 1255-1265. doi: 10.1208/s12249-012-9850-z
2009
Conference Publication
Formation of progesterone loaded-solid dispersion systems prepared using a particle from gas-saturated suspension (PGSS) method
Falconer, James R. , Tallon, Steven , Farid, Mohammed , Chen, John J. and Alany, Raid (2009). Formation of progesterone loaded-solid dispersion systems prepared using a particle from gas-saturated suspension (PGSS) method. Out Of The Wilderness: Australasian Pharmaceutical Science Association Annual Conference 2009 (APSA), Hobart, TAS Australia, 8-11 December 2009. Mt. Waverley, VIC Australia: Australasian Pharmaceutical Science Association Conference (APSA).
2008
Journal Article
Self-built supercritical CO2 anti-solvent unit design, construction and operation using Carbamazepine
Meng, Dan, Falconer, James, Krauel-Goellner, Karen, Chen, John J. J. J., Farid, Mohammed and Alany, Raid G. (2008). Self-built supercritical CO2 anti-solvent unit design, construction and operation using Carbamazepine. AAPS PharmSciTech, 9 (3), 944-952. doi: 10.1208/s12249-008-9130-0
2008
Conference Publication
Medication Reconciliation - Easy concept, difficult task
Ng, Jerome , Falconer, James R., Nguyan, Truc and Brkic, Lejla (2008). Medication Reconciliation - Easy concept, difficult task. Centre for Clinical Research and Effective Practice (CCRep), Auckland, New Zealand, 15 July 2008. Middlemore Hospital, Counties Manukau District Health Board (CMDHB):
Funding
Past funding
Supervision
Availability
- Dr James Robert Falconer is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Extraction of psilocybin and psilocin from the psilocybe mushroom (Magic Mushroom) utilising a single-pot supercritical carbon dioxide (scCO2) method
Principal Advisor
Other advisors: Associate Professor Peter Moyle
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Doctor Philosophy
Extraction of bioactives from natural resources using supercritical fluid technology and their activity testing for the pharmaceutical and food industry
Principal Advisor
Other advisors: Associate Professor Marie-Odile Parat
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Doctor Philosophy
Extraction of psilocybin and psilocin from the psilocybe mushroom (Magic Mushroom) utilising a single-pot supercritical carbon dioxide (scCO2) method
Principal Advisor
Other advisors: Associate Professor Peter Moyle
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Doctor Philosophy
The development and optimization of a transdermal firocoxib microemulsion gel for dogs
Associate Advisor
Other advisors: Dr Halley Ravuri, Professor Paul Mills
Completed supervision
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2022
Doctor Philosophy
Advanced Formulation Technologies for Oral Delivery of Antimicrobial Agents
Principal Advisor
Other advisors: Associate Professor Amirali Popat, Professor Mark Blaskovich
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2022
Doctor Philosophy
Nose-to-Brain Delivery of Clozapine in Sol-Gel Systems
Principal Advisor
Other advisors: Professor Dan Siskind, Dr Harendra Parekh
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2022
Doctor Philosophy
Investigation into the selective extraction of cannabinoids from cannabis using supercritical carbon dioxide
Principal Advisor
Other advisors: Dr Harendra Parekh
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2021
Doctor Philosophy
Advanced Oral Antibiotic Formulations
Principal Advisor
Other advisors: Professor Jason Roberts, Professor Peter Cabot, Associate Professor Amirali Popat, Dr Fekade Sime
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2020
Doctor Philosophy
Development of a liposomal platform using green supercritical fluid technology: application towards repurposing and tumour-targeting of albendazole for cancer therapy
Principal Advisor
Other advisors: Associate Professor Peter Moyle
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2019
Doctor Philosophy
Novel extraction and evaluation of papaya leaf for chemotherapeutic molecules
Principal Advisor
Other advisors: Professor Nick Shaw, Associate Professor Marie-Odile Parat
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2024
Doctor Philosophy
The development and optimization of a transdermal firocoxib microemulsion gel for dogs
Associate Advisor
Other advisors: Dr Halley Ravuri, Professor Paul Mills
Media
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