Associate Professor Amirali Popat
Associate Professor

Amirali Popat

Email: 
Phone: 
+61 7 334 61870

Background

Research Interests

  • Advanced Drug Delivery and Nanomedicine 1.Advanced drug delivery methods (controlled release dosage forms such as tablets, granules and microspheres) 2. Biomaterials as next generation adjuvant for vaccine delivery 3. Surface modified nanomaterials (Silica, Polymer, Liposomes) 4. Programmable nanoparticales for oral drug delivery and targeting 5. Translocation of nanoparticles after oral drug delivery (In-vitro and In-vivo)

Qualifications

  • Master of Pharmaceutical Science, Gujarat University
  • Bachelor of Pharmacy, Gujarat University

Availability

Associate Professor Amirali Popat is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Chemical Sciences Inorganic chemistry Nanobiotechnology Nanomaterials Nanomedicine Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Pharmacy, Gujarat University
  • Masters (Research), Gujarat University

Research interests

  • Advanced Drug Delivery and Nanomedicine

    1.Advanced drug delivery methods (controlled release dosage forms such as tablets, granules and microspheres) 2. Biomaterials as next generation adjuvant for vaccine delivery 3. Surface modified nanomaterials (Silica, Polymer, Liposomes) 4. Programmable nanoparticales for oral drug delivery and targeting 5. Translocation of nanoparticles after oral drug delivery (In-vitro and In-vivo)

Search Professor Amirali Popat’s works on UQ eSpace

104 works between 2011 and 2024
All (104) Journal Article (94) Book Chapter (3) Conference Publication (2) Other Outputs (5)

1 - 20 of 104 works

2024

Journal Article

A translational framework to DELIVER nanomedicines to the clinic

Joyce, Paul, Allen, Christine J., Alonso, María José, Ashford, Marianne, Bradbury, Michelle S., Germain, Matthieu, Kavallaris, Maria, Langer, Robert, Lammers, Twan, Peracchia, Maria Teresa, Popat, Amirali, Prestidge, Clive A., Rijcken, Cristianne J. F., Sarmento, Bruno, Schmid, Ruth B., Schroeder, Avi, Subramaniam, Santhni, Thorn, Chelsea R., Whitehead, Kathryn A., Zhao, Chun-Xia and Santos, Hélder A. (2024). A translational framework to DELIVER nanomedicines to the clinic. Nature Nanotechnology. doi: 10.1038/s41565-024-01754-7

A translational framework to DELIVER nanomedicines to the clinic

2024

Journal Article

Clinical translation of 3D printed pharmaceuticals

Krueger, Liam, Awad, Atheer, Basit, Abdul W., Goyanes, Alvaro, Miles, Jared A. and Popat, Amirali (2024). Clinical translation of 3D printed pharmaceuticals. Nature Reviews Bioengineering, 1-3. doi: 10.1038/s44222-024-00217-x

Clinical translation of 3D printed pharmaceuticals

2024

Journal Article

Engineered smart materials for RNA based molecular therapy to treat Glioblastoma

Singh, Ravi Raj, Mondal, Indranil, Janjua, Taskeen, Popat, Amirali and Kulshreshtha, Ritu (2024). Engineered smart materials for RNA based molecular therapy to treat Glioblastoma. Bioactive Materials, 33, 396-423. doi: 10.1016/j.bioactmat.2023.11.007

Engineered smart materials for RNA based molecular therapy to treat Glioblastoma

2024

Journal Article

Cannabidiol - help and hype in targeting mucosal diseases

Moniruzzaman, Md, Janjua, Taskeen Iqbal, Martin, Jennifer H., Begun, Jakob and Popat, Amirali (2024). Cannabidiol - help and hype in targeting mucosal diseases. Journal of Controlled Release, 365, 530-543. doi: 10.1016/j.jconrel.2023.11.010

Cannabidiol - help and hype in targeting mucosal diseases

2023

Other Outputs

Extended-release formulations comprising 6-thioguanine 

Florin, Timothy, Popat, Amirali and Jambhrunkar, Siddharth (2023). Extended-release formulations comprising 6-thioguanine . CA3038602C.

Extended-release formulations comprising 6-thioguanine 

2023

Journal Article

Surface functionalization affects the retention and bio-distribution of orally administered mesoporous silica nanoparticles in a colitis mouse model

Schmid, Roman, Volcic, Meta, Fischer, Stephan, Qu, Zhi, Barth, Holger, Popat, Amirali, Kirchhoff, Frank and Lindén, Mika (2023). Surface functionalization affects the retention and bio-distribution of orally administered mesoporous silica nanoparticles in a colitis mouse model. Scientific Reports, 13 (1) 20175, 1-17. doi: 10.1038/s41598-023-47445-6

Surface functionalization affects the retention and bio-distribution of orally administered mesoporous silica nanoparticles in a colitis mouse model

2023

Journal Article

Silica nanoparticles: a review of their safety and current strategies to overcome biological barriers

Janjua, Taskeen Iqbal, Cao, Yuxue, Kleitz, Freddy, Linden, Mika, Yu, Chengzhong and Popat, Amirali (2023). Silica nanoparticles: a review of their safety and current strategies to overcome biological barriers. Advanced Drug Delivery Reviews, 203 115115, 115115. doi: 10.1016/j.addr.2023.115115

Silica nanoparticles: a review of their safety and current strategies to overcome biological barriers

2023

Journal Article

Silica nanoparticles for brain cancer

Feng, Yuran, Cao, Yuxue, Singh, Ravi, Janjua, Taskeen Iqbal and Popat, Amirali (2023). Silica nanoparticles for brain cancer. Expert Opinion on Drug Delivery, 20 (12), 1749-1767. doi: 10.1080/17425247.2023.2273830

Silica nanoparticles for brain cancer

2023

Journal Article

Porous silicon embedded in a thermoresponsive hydrogel for intranasal delivery of lipophilic drugs to treat rhinosinusitis

Bakshi, Shrishty, Pandey, Preeti, Mohammed, Yousuf, Wang, Joanna, Sailor, Michael J., Popat, Amirali, Parekh, Harendra S. and Kumeria, Tushar (2023). Porous silicon embedded in a thermoresponsive hydrogel for intranasal delivery of lipophilic drugs to treat rhinosinusitis. Journal of Controlled Release, 363, 452-463. doi: 10.1016/j.jconrel.2023.09.045

Porous silicon embedded in a thermoresponsive hydrogel for intranasal delivery of lipophilic drugs to treat rhinosinusitis

2023

Journal Article

Osteoimmune-modulating and BMP-2-eluting anodised 3D printed titanium for accelerated bone regeneration

Ali, Masood, He, Yan, Chang, Anna Sze Ni, Wu, Alice, Liu, Jingyu, Cao, Yuxue, Mohammad, Yousuf, Popat, Amirali, Walsh, Laurie, Ye, Qingsong, Xu, Chun and Kumeria, Tushar (2023). Osteoimmune-modulating and BMP-2-eluting anodised 3D printed titanium for accelerated bone regeneration. Journal of Materials Chemistry B, 12 (1), 97-111. doi: 10.1039/d3tb01029e

Osteoimmune-modulating and BMP-2-eluting anodised 3D printed titanium for accelerated bone regeneration

2023

Journal Article

Clinical translation of metal–organic frameworks

Tyagi, Nisha, Wijesundara, Yalini H., Gassensmith, Jeremiah J. and Popat, Amirali (2023). Clinical translation of metal–organic frameworks. Nature Reviews Materials, 8 (11), 701-703. doi: 10.1038/s41578-023-00608-3

Clinical translation of metal–organic frameworks

2023

Conference Publication

Nanomedicine And Gene Therapy To Treat Glioblastoma

Singh, Ravi, Popat, Amirali and Kulshreshtha, Ritu (2023). Nanomedicine And Gene Therapy To Treat Glioblastoma. IBRO 11th World Congress of Neuroscience, Granada, Spain, 9-13 September 2023. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.ibneur.2023.08.1290

Nanomedicine And Gene Therapy To Treat Glioblastoma

2023

Journal Article

Virus-like silica nanoparticles improve permeability of macromolecules across the blood–brain barrier in vitro

Feng, Yuran, Cao, Yuxue, Qu, Zhi, Janjua, Taskeen Iqbal and Popat, Amirali (2023). Virus-like silica nanoparticles improve permeability of macromolecules across the blood–brain barrier in vitro. Pharmaceutics, 15 (9) 2239, 2239. doi: 10.3390/pharmaceutics15092239

Virus-like silica nanoparticles improve permeability of macromolecules across the blood–brain barrier in vitro

2023

Journal Article

3D printing tablets for high-precision dose titration of caffeine

Krueger, Liam, Cao, Yuxue, Zheng, Zheng, Ward, Jason, Miles, Jared A. and Popat, Amirali (2023). 3D printing tablets for high-precision dose titration of caffeine. International Journal of Pharmaceutics, 642 123132, 1-9. doi: 10.1016/j.ijpharm.2023.123132

3D printing tablets for high-precision dose titration of caffeine

2023

Journal Article

Clinical translation of extracellular vesicles

Ghodasara, Aayushi, Raza, Aun, Wolfram, Joy, Salomon, Carlos and Popat, Amirali (2023). Clinical translation of extracellular vesicles. Advanced Healthcare Materials, 12 (28) 2301010, e2301010. doi: 10.1002/adhm.202301010

Clinical translation of extracellular vesicles

2023

Journal Article

Engineering nano-cellulose bio-composites to improve protein delivery for oral vaccination

Cao, Pei, Amiralian, Nasim, Wang, Jingjing, Sun, Bing, Popat, Amirali, Xie, Fengwei, Xu, Zhi Ping, Li, Yan and Li, Li (2023). Engineering nano-cellulose bio-composites to improve protein delivery for oral vaccination. Biomaterials Advances, 149 213400, 1-11. doi: 10.1016/j.bioadv.2023.213400

Engineering nano-cellulose bio-composites to improve protein delivery for oral vaccination

2023

Journal Article

Influence of pore size and surface functionalization of mesoporous silica nanoparticles on the solubility and antioxidant activity of confined coenzyme Q10

Meka, Anand Kumar, Gopalakrishna, Akshatha, Iriarte-Mesa, Claudia, Rewatkar, Prarthana, Qu, Zhi, Wu, Xiaoxin, Cao, Yuxue, Prasadam, Indira, Janjua, Taskeen Iqbal, Kleitz, Freddy, Kumeria, Tushar and Popat, Amirali (2023). Influence of pore size and surface functionalization of mesoporous silica nanoparticles on the solubility and antioxidant activity of confined coenzyme Q10. Molecular Pharmaceutics, 20 (6), 2966-2977. doi: 10.1021/acs.molpharmaceut.3c00017

Influence of pore size and surface functionalization of mesoporous silica nanoparticles on the solubility and antioxidant activity of confined coenzyme Q10

2023

Journal Article

Virus-like silica nanoparticles enhance macromolecule permeation in vivo

Cao, Yuxue, Janjua, Taskeen Iqbal, Qu, Zhi, Draphoen, Bastian, Bai, Yunfan, Linden, Mika, Moniruzzaman, Md., Hasnain, Sumaira Z., Kumeria, Tushar and Popat, Amirali (2023). Virus-like silica nanoparticles enhance macromolecule permeation in vivo. Biomaterials Science, 11 (13), 4508-4521. doi: 10.1039/d3bm00137g

Virus-like silica nanoparticles enhance macromolecule permeation in vivo

2023

Journal Article

Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma

Janjua, Taskeen Iqbal, Cao, Yuxue, Ahmed-Cox, Aria, Raza, Aun, Moniruzzaman, Md, Akhter, Dewan Taslima, Fletcher, Nicholas L., Kavallaris, Maria, Thurecht, Kristofer J. and Popat, Amirali (2023). Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma. Journal of Controlled Release, 357, 161-174. doi: 10.1016/j.jconrel.2023.03.040

Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma

2023

Journal Article

Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides

Alharthi, Sitah, Popat, Amirali, Ziora, Zyta Maria and Moyle, Peter Michael (2023). Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides. Molecules, 28 (5) 2114, 1-17. doi: 10.3390/molecules28052114

Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides

Current funding

  • 2024 - 2025
    Targeting brain tumour using rationally designed nanomedicine
    Brain Foundation Research Grant
    Open grant
  • 2024 - 2025
    Ultrasmall nanoparticles for overcoming biological barriers in the treatment of Glioblastoma
    Cure Cancer Early Career Research Grants
    Open grant
  • 2023 - 2028
    ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance (ARC CEA-StAR)
    ARC Industrial Transformation Training Centres
    Open grant
  • 2020 - 2025
    Ovarian cancer early detection, monitoring and therapeutic intervention using extracellular vesicles
    NHMRC MRFF EPCDR - Ovarian Cancer Research
    Open grant

Past funding

  • 2023 - 2024
    Overcome biological barriers in cancer for the treatment of glioblastoma using personalised nanomedicine
    TdC Pioneering Grant
    Open grant
  • 2023
    Compounding Personalised Medicines using 3D Printing
    UQ Knowledge Exchange & Translation Fund
    Open grant
  • 2021 - 2024
    Innovative delivery methods for the biologic soluble RAGE to prevent Type 1 Diabetes
    JDRF Pilot and Innovation Awards
    Open grant
  • 2019
    Enhanced osseointegration on growth factor releasing anodized 3D printed titanium dental implants with titania nanotubes
    Australian Dental Research Fund Inc
    Open grant
  • 2019 - 2021
    Parameters controlling naonparticle biodistribution upon oral administration under inflammatory conditions (Siloral)
    DAAD - German Academic Exchange Service
    Open grant
  • 2018 - 2020
    Encapsulation of plant extracts formulation using variety of protein based nanoparticles (former C03644-001)
    Integria Healthcare (Australia) Pty Ltd
    Open grant
  • 2018 - 2021
    Platform Nanotechnologies for Oral Delivery of Drugs, Therapeutic Protein and Peptide Delivery
    NHMRC Career Development Fellowship
    Open grant
  • 2017 - 2023
    Australian Centre for Cannabinoids and Research Excellence (ACRE): Quality and safety in the implementation of medicinal cannabis use in the community (NHMRC CRE administered by University of Newcastl
    University of Newcastle
    Open grant
  • 2016 - 2018
    HDAC3 as a novel orchestrator of lipid oxidation in the intestine and potential therapeutic target in obesity (NHMRC Project Grant administered by La Trobe University)
    La Trobe University
    Open grant
  • 2015
    Programmable nanoparticles for the treatment of Inflammatory Bowel Disease
    UQ Early Career Researcher
    Open grant
  • 2014 - 2017
    NHMRC Early Career Fellowship (Peter Doherty - Australian Biomedical Fellowship): Bioresponsive nanocarriers for controlled and targeted delivery to efficiently treat Inflamatory Bowel Disease (IBD)
    NHMRC Early Career Fellowships
    Open grant
  • 2014 - 2015
    Nanoencapsulation of bifenthrin for higher stability, efficacy, and controlled release.
    UQ Collaboration and Industry Engagement Fund - Seed Research Grant
    Open grant

Availability

Associate Professor Amirali Popat is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Engineering nanoexosomes for targeted drug delivery

    Principal Advisor

    Other advisors: Professor Carlos Salomon Gallo

  • Doctor Philosophy

    Smart Silica nanoparticles for oral biologics delivery

    Principal Advisor

    Other advisors: Dr Sumaira Hasnain

  • Doctor Philosophy

    Nanomedicine and Gene Therapy to Treat Glioblastoma

    Principal Advisor

  • Doctor Philosophy

    3D printed pharmaceuticals for novel oral dosage form design

    Principal Advisor

    Other advisors: Dr Jared Miles

  • Doctor Philosophy

    Nanomedicine and gene therapy for meningioma treatment

    Principal Advisor

  • Doctor Philosophy

    Development of Metal Organic Frameworks for targeted oral drug delivery

    Principal Advisor

    Other advisors: Professor Mark Blaskovich

  • Doctor Philosophy

    Targeting Brain Cancer using Personalised Nanomedicine

    Principal Advisor

  • Doctor Philosophy

    Designer Nanoparticles for Oral and Targeted Delivery of Protein Therapeutics

    Principal Advisor

    Other advisors: Associate Professor Jakob Begun, Dr Md Moniruzzaman

  • Doctor Philosophy

    Development and evaluation of composite sol-gels for delivery to mucosal tissue

    Associate Advisor

    Other advisors: Dr Jared Miles

  • Doctor Philosophy

    ANTIVIRULENCE AGENT NANOFORMULATIONS: A NOVEL STRATEGY TO OVERCOME ANTIBIOTIC RESISTANCE

    Associate Advisor

    Other advisors: Dr Ben Ross, Dr Jared Miles, Dr Zyta M Ziora, Associate Professor Peter Moyle, Dr Jaya Seneviratne

  • Doctor Philosophy

    Selective laser sintering (SLS) application in 3D printed medicines

    Associate Advisor

    Other advisors: Dr Ben Ross, Dr Jared Miles

  • Doctor Philosophy

    Computer assisted discovery of novel tight junction modulators for oral delivery of biologics and nanomedicines

    Associate Advisor

    Other advisors: Dr Jared Miles, Dr Ben Ross

Completed supervision

Enquiries

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