Professor Amirali Popat
Professor

Amirali Popat

Email: 
Phone: 
+61 7 334 61870

Background

Research Interests

  • Advanced Drug Delivery and Nanomedicine 1.Advanced drug delivery methods (controlled release dosage forms such as tablets, granules and microspheres) 2. Biomaterials as next generation adjuvant for vaccine delivery 3. Surface modified nanomaterials (Silica, Polymer, Liposomes) 4. Programmable nanoparticales for oral drug delivery and targeting 5. Translocation of nanoparticles after oral drug delivery (In-vitro and In-vivo)

Qualifications

  • Master of Pharmaceutical Science, Gujarat University
  • Bachelor of Pharmacy, Gujarat University

Availability

Professor Amirali Popat is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Chemical Sciences Inorganic chemistry Nanobiotechnology Nanomaterials Nanomedicine Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Pharmacy, Gujarat University
  • Masters (Research), Gujarat University

Research interests

  • Advanced Drug Delivery and Nanomedicine

    1.Advanced drug delivery methods (controlled release dosage forms such as tablets, granules and microspheres) 2. Biomaterials as next generation adjuvant for vaccine delivery 3. Surface modified nanomaterials (Silica, Polymer, Liposomes) 4. Programmable nanoparticales for oral drug delivery and targeting 5. Translocation of nanoparticles after oral drug delivery (In-vitro and In-vivo)

Search Professor Amirali Popat’s works on UQ eSpace

108 works between 2011 and 2025
All (108) Journal Article (97) Book Chapter (3) Conference Publication (3) Other Outputs (5)

61 - 80 of 108 works

2020

Journal Article

Silica nanoparticles: a promising platform for enhanced oral delivery of macromolecules

Abeer, Muhammad Mustafa, Rewatkar, Prarthana, Qu, Zhi, Talekar, Meghna, Kleitz, Freddy, Schmid, Roman, Lindén, Mika, Kumeria, Tushar and Popat, Amirali (2020). Silica nanoparticles: a promising platform for enhanced oral delivery of macromolecules. Journal of Controlled Release, 326, 544-555. doi: 10.1016/j.jconrel.2020.07.021

Silica nanoparticles: a promising platform for enhanced oral delivery of macromolecules

2020

Journal Article

Formulation technologies and advances for oral delivery of novel nitroimidazoles and antimicrobial peptides

Ndayishimiye, John, Popat, Amirali, Blaskovich, Mark and Falconer, James Robert (2020). Formulation technologies and advances for oral delivery of novel nitroimidazoles and antimicrobial peptides. Journal of Controlled Release, 324, 728-749. doi: 10.1016/j.jconrel.2020.05.002

Formulation technologies and advances for oral delivery of novel nitroimidazoles and antimicrobial peptides

2020

Journal Article

Gastro-protective protein-silica nanoparticles formulation for oral drug delivery: In vitro release, cytotoxicity and mitochondrial activity

Juère, Estelle, Del Favero, Giorgia, Masse, Florence, Marko, Doris, Popat, Amirali, Florek, Justyna, Caillard, Romain and Kleitz, Freddy (2020). Gastro-protective protein-silica nanoparticles formulation for oral drug delivery: In vitro release, cytotoxicity and mitochondrial activity. European Journal of Pharmaceutics and Biopharmaceutics, 151, 171-180. doi: 10.1016/j.ejpb.2020.03.015

Gastro-protective protein-silica nanoparticles formulation for oral drug delivery: In vitro release, cytotoxicity and mitochondrial activity

2020

Journal Article

Oral delivery of β-lactoglobulin nanospheres encapsulated resveratrol alleviates inflammation in Winnie mice with spontaneous ulcerative colitis

Pujara, Naisarg, Wong, Kuan Yau, Qu, Zhi, Wang, Ran, Moniruzzaman, Md., Rewatkar, Prarthana, Kumeria, Tushar, Ross, Benjamin P., McGuckin, Michael and Popat, Amirali (2020). Oral delivery of β-lactoglobulin nanospheres encapsulated resveratrol alleviates inflammation in Winnie mice with spontaneous ulcerative colitis. Molecular Pharmaceutics, 18 (2) acs.molpharmaceut.0c00048, 627-640. doi: 10.1021/acs.molpharmaceut.0c00048

Oral delivery of β-lactoglobulin nanospheres encapsulated resveratrol alleviates inflammation in Winnie mice with spontaneous ulcerative colitis

2020

Journal Article

The solid progress of nanomedicine

Martins, João Pedro, das Neves, José, de la Fuente, María, Celia, Christian, Florindo, Helena, Günday-Türeli, Nazende, Popat, Amirali, Santos, José Luis, Sousa, Flávia, Schmid, Ruth, Wolfram, Joy, Sarmento, Bruno and Santos, Hélder A. (2020). The solid progress of nanomedicine. Drug Delivery and Translational Research, 10 (3), 726-729. doi: 10.1007/s13346-020-00743-2

The solid progress of nanomedicine

2020

Journal Article

Polymer-mesoporous silica nanoparticle core-shell nanofibers as a dual-drug-delivery system for guided tissue regeneration

Xu, Chun, Cao, Yuxue, Lei, Chang, Li, Zhihao, Kumeria, Tushar, Meka, Anand Kumar, Xu, Jia, Liu, Jingyu, Yan, Cheng, Luo, Lihua, Khademhosseini, Ali, Popat, Amirali, He, Yan and Ye, Qingsong (2020). Polymer-mesoporous silica nanoparticle core-shell nanofibers as a dual-drug-delivery system for guided tissue regeneration. ACS Applied Nano Materials, 3 (2), 1457-1467. doi: 10.1021/acsanm.9b02298

Polymer-mesoporous silica nanoparticle core-shell nanofibers as a dual-drug-delivery system for guided tissue regeneration

2020

Book Chapter

Size, shape and surface charge considerations of orally delivered nanomedicines

Rewatkar, Prarthana, Kumeria, Tushar and Popat, Amirali (2020). Size, shape and surface charge considerations of orally delivered nanomedicines. Nanotechnology for oral drug delivery. (pp. 143-176) edited by João Pedro Martins and Hélder A. Santos. London, United Kingdom: Elsevier. doi: 10.1016/b978-0-12-818038-9.00005-3

Size, shape and surface charge considerations of orally delivered nanomedicines

2019

Journal Article

Efficient photoacoustic imaging using indocyanine green (ICG) loaded functionalized mesoporous silica nanoparticles

Chaudhary, Zanib, Khan, Gul Majid, Abeer, Muhammad Mustafa, Pujara, Naisarg, Wan-Chi Tse, Brian, McGuckin, Michael A., Popat, Amirali and Kumeria, Tushar (2019). Efficient photoacoustic imaging using indocyanine green (ICG) loaded functionalized mesoporous silica nanoparticles. Biomaterials Science, 7 (12), 5002-5015. doi: 10.1039/c9bm00822e

Efficient photoacoustic imaging using indocyanine green (ICG) loaded functionalized mesoporous silica nanoparticles

2019

Journal Article

Encapsulation and controlled release of Resveratrol within functionalized mesoporous silica nanoparticles for prostate cancer therapy

Chaudhary, Zanib, Subramaniam, Sugarniya, Khan, Gul Majid, Abeer, Muhammad Mustafa, Qu, Zhi, Janjua, Taskeen, Kumeria, Tushar, Batra, Jyotsna and Popat, Amirali (2019). Encapsulation and controlled release of Resveratrol within functionalized mesoporous silica nanoparticles for prostate cancer therapy. Frontiers in Bioengineering and Biotechnology, 7 225, 225. doi: 10.3389/fbioe.2019.00225

Encapsulation and controlled release of Resveratrol within functionalized mesoporous silica nanoparticles for prostate cancer therapy

2019

Journal Article

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity

Sheng, Yong Hua, Wong, Kuan Yau, Seim, Inge, Wang, Ran, He, Yaowu, Wu, Andy, Patrick, Maya, Lourie, Rohan, Schreiber, Veronika, Giri, Rabina, Ng, Choa Ping, Popat, Amirali, Hooper, John, Kijanka, Gregor, Florin, Timothy H., Begun, Jakob, Radford, Kristen J., Hasnain, Sumaira and McGuckin, Michael A. (2019). MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity. Oncogene, 38 (48), 7294-7310. doi: 10.1038/s41388-019-0951-y

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity

2019

Journal Article

Rationally designed dendritic silica nanoparticles for oral delivery of exenatide

Abeer, Muhammad Mustafa, Meka, Anand Kumar, Pujara, Naisarg, Kumeria, Tushar, Strounina, Ekaterina, Nunes, Rute, Costa, Ana, Sarmento, Bruno, Hasnain, Sumaira Z., Ross, Benjamin P. and Popat, Amirali (2019). Rationally designed dendritic silica nanoparticles for oral delivery of exenatide. Pharmaceutics, 11 (8) 418, 418. doi: 10.3390/pharmaceutics11080418

Rationally designed dendritic silica nanoparticles for oral delivery of exenatide

2019

Journal Article

Succinylated β-lactoglobuline-functionalized multiwalled carbon nanotubes with improved colloidal stability and biocompatibility

Jain, Sanyog, Dongave, Shesherao M., Date, Tushar, Kushwah, Varun, Mahajan, Rahul R., Pujara, Naisarg, Kumeria, Tushar and Popat, Amirali (2019). Succinylated β-lactoglobuline-functionalized multiwalled carbon nanotubes with improved colloidal stability and biocompatibility. ACS Biomaterials Science and Engineering, 5 (7) acsbiomaterials.9b00268, 3361-3372. doi: 10.1021/acsbiomaterials.9b00268

Succinylated β-lactoglobuline-functionalized multiwalled carbon nanotubes with improved colloidal stability and biocompatibility

2019

Journal Article

Treatment of atherosclerotic plaque: perspectives on theranostics

Zhang, Yicong, Koradia, Aayushi, Kamato, Danielle, Popat, Amirali, Little, Peter J. and Ta, Hang T. (2019). Treatment of atherosclerotic plaque: perspectives on theranostics. Journal of Pharmacy and Pharmacology, 71 (7) jphp.13092, 1029-1043. doi: 10.1111/jphp.13092

Treatment of atherosclerotic plaque: perspectives on theranostics

2019

Journal Article

Environmental copper sensor based on polyethylenimine-functionalized nanoporous anodic alumina interferometers

Kaur, Simarpreet, Law, Cheryl Suwen, Williamson, Nathan Hu, Kempson, Ivan, Popat, Amirali, Kumeria, Tushar and Santos, Abel (2019). Environmental copper sensor based on polyethylenimine-functionalized nanoporous anodic alumina interferometers. Analytical Chemistry, 91 (8) acs.analchem.8b04963, 5011-5020. doi: 10.1021/acs.analchem.8b04963

Environmental copper sensor based on polyethylenimine-functionalized nanoporous anodic alumina interferometers

2019

Book Chapter

Luminescent porous silicon nanoparticles for continuous wave and time-gated photoluminescence imaging

Kumeria, Tushar, Qu, Zhi, Popat, Amirali, Altalhi, Tariq and Santos, Abel (2019). Luminescent porous silicon nanoparticles for continuous wave and time-gated photoluminescence imaging. Theranostics: methods and protocols. (pp. 185-198) New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-9769-5_13

Luminescent porous silicon nanoparticles for continuous wave and time-gated photoluminescence imaging

2018

Journal Article

Enhanced solubility, permeability and anticancer activity of vorinostat using tailored mesoporous silica nanoparticles

Meka, Anand, Jenkins, Laura, Dàvalos-Salas, Mercedes, Pujara, Naisarg, Wong, Kuan, Kumeria, Tushar, Mariadason, John and Popat, Amirali (2018). Enhanced solubility, permeability and anticancer activity of vorinostat using tailored mesoporous silica nanoparticles. Pharmaceutics, 10 (4) 283, 283. doi: 10.3390/pharmaceutics10040283

Enhanced solubility, permeability and anticancer activity of vorinostat using tailored mesoporous silica nanoparticles

2018

Journal Article

ε-Poly-l-Lysine/plasmid DNA nanoplexes for efficient gene delivery in vivo

Mandal, Haimanti, Katiyar, Sameer S, Swami, Rajan, Kushwah, Varun, Katare, Parmeshwar B, Kumar Meka, Anand, Banerjee, Sanjay K, Popat, Amirali and Jain, Sanyog (2018). ε-Poly-l-Lysine/plasmid DNA nanoplexes for efficient gene delivery in vivo. International Journal of Pharmaceutics, 542 (1-2), 142-152. doi: 10.1016/j.ijpharm.2018.03.021

ε-Poly-l-Lysine/plasmid DNA nanoplexes for efficient gene delivery in vivo

2018

Journal Article

A well-tolerated and rapidly acting thiopurine for IBD?

Florin, Timothy H. J., Wright, John D., Jambhrunkar, Siddharth D., Henman, Michael G. and Popat, Amirali (2018). A well-tolerated and rapidly acting thiopurine for IBD?. Drug Discovery Today, 24 (1), 37-41. doi: 10.1016/j.drudis.2018.09.001

A well-tolerated and rapidly acting thiopurine for IBD?

2017

Journal Article

In vitro dissolution, cellular membrane permeability and anti-inflammatory response of resveratrol-encapsulated mesoporous silica nanoparticles

Juere, Estelle, Florek, Justyna, Bouchoucha, Meryem, Jambhnukar, Siddharth, Wong, Kuan Yau, Popat, Amirali and Kleitz, Freddy (2017). In vitro dissolution, cellular membrane permeability and anti-inflammatory response of resveratrol-encapsulated mesoporous silica nanoparticles. Molecular Pharmaceutics, 14 (12), 4431-4441. doi: 10.1021/acs.molpharmaceut.7b00529

In vitro dissolution, cellular membrane permeability and anti-inflammatory response of resveratrol-encapsulated mesoporous silica nanoparticles

2017

Journal Article

Stably engineered nanobubbles and ultrasound - An effective platform for enhanced macromolecular delivery to representative cells of the retina

Thakur, Sachin S., Ward, Micheal S., Popat, Amirali, Flemming, Nicole B., Parat, Marie-Odile, Barnett, Nigel L. and Parekh, Harendra S. (2017). Stably engineered nanobubbles and ultrasound - An effective platform for enhanced macromolecular delivery to representative cells of the retina. Plos One, 12 (5) e0178305, e0178305. doi: 10.1371/journal.pone.0178305

Stably engineered nanobubbles and ultrasound - An effective platform for enhanced macromolecular delivery to representative cells of the retina

Current funding

  • 2024 - 2025
    Targeting brain tumour using rationally designed nanomedicine
    Brain Foundation Research Grant
    Open grant
  • 2023 - 2028
    ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance (ARC CEA-StAR)
    ARC Industrial Transformation Training Centres
    Open grant
  • 2020 - 2025
    Ovarian cancer early detection, monitoring and therapeutic intervention using extracellular vesicles
    NHMRC MRFF EPCDR - Ovarian Cancer Research
    Open grant

Past funding

  • 2024 - 2025
    Ultrasmall nanoparticles for overcoming biological barriers in the treatment of Glioblastoma
    Cure Cancer Early Career Research Grants
    Open grant
  • 2023 - 2024
    Overcome biological barriers in cancer for the treatment of glioblastoma using personalised nanomedicine
    TdC Pioneering Grant
    Open grant
  • 2023
    Compounding Personalised Medicines using 3D Printing
    UQ Knowledge Exchange & Translation Fund
    Open grant
  • 2021 - 2024
    Innovative delivery methods for the biologic soluble RAGE to prevent Type 1 Diabetes
    JDRF Pilot and Innovation Awards
    Open grant
  • 2019
    Enhanced osseointegration on growth factor releasing anodized 3D printed titanium dental implants with titania nanotubes
    Australian Dental Research Fund Inc
    Open grant
  • 2019 - 2021
    Parameters controlling naonparticle biodistribution upon oral administration under inflammatory conditions (Siloral)
    DAAD - German Academic Exchange Service
    Open grant
  • 2018 - 2020
    Encapsulation of plant extracts formulation using variety of protein based nanoparticles (former C03644-001)
    Integria Healthcare (Australia) Pty Ltd
    Open grant
  • 2018 - 2021
    Platform Nanotechnologies for Oral Delivery of Drugs, Therapeutic Protein and Peptide Delivery
    NHMRC Career Development Fellowship
    Open grant
  • 2017 - 2023
    Australian Centre for Cannabinoids and Research Excellence (ACRE): Quality and safety in the implementation of medicinal cannabis use in the community (NHMRC CRE administered by University of Newcastl
    University of Newcastle
    Open grant
  • 2016 - 2018
    HDAC3 as a novel orchestrator of lipid oxidation in the intestine and potential therapeutic target in obesity (NHMRC Project Grant administered by La Trobe University)
    La Trobe University
    Open grant
  • 2015
    Programmable nanoparticles for the treatment of Inflammatory Bowel Disease
    UQ Early Career Researcher
    Open grant
  • 2014 - 2017
    NHMRC Early Career Fellowship (Peter Doherty - Australian Biomedical Fellowship): Bioresponsive nanocarriers for controlled and targeted delivery to efficiently treat Inflamatory Bowel Disease (IBD)
    NHMRC Early Career Fellowships
    Open grant
  • 2014 - 2015
    Nanoencapsulation of bifenthrin for higher stability, efficacy, and controlled release.
    UQ Collaboration and Industry Engagement Fund - Seed Research Grant
    Open grant

Availability

Professor Amirali Popat is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

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