Professor Amirali Popat
Professor

Amirali Popat

Email: 
Phone: 
+61 7 334 61870

Background

Research Interests

  • Advanced Drug Delivery and Nanomedicine 1.Advanced drug delivery methods (controlled release dosage forms such as tablets, granules and microspheres) 2. Biomaterials as next generation adjuvant for vaccine delivery 3. Surface modified nanomaterials (Silica, Polymer, Liposomes) 4. Programmable nanoparticales for oral drug delivery and targeting 5. Translocation of nanoparticles after oral drug delivery (In-vitro and In-vivo)

Qualifications

  • Master of Pharmaceutical Science, Gujarat University
  • Bachelor of Pharmacy, Gujarat University

Availability

Professor Amirali Popat is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Chemical Sciences Inorganic chemistry Nanobiotechnology Nanomaterials Nanomedicine Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Pharmacy, Gujarat University
  • Masters (Research), Gujarat University

Research interests

  • Advanced Drug Delivery and Nanomedicine

    1.Advanced drug delivery methods (controlled release dosage forms such as tablets, granules and microspheres) 2. Biomaterials as next generation adjuvant for vaccine delivery 3. Surface modified nanomaterials (Silica, Polymer, Liposomes) 4. Programmable nanoparticales for oral drug delivery and targeting 5. Translocation of nanoparticles after oral drug delivery (In-vitro and In-vivo)

Search Professor Amirali Popat’s works on UQ eSpace

108 works between 2011 and 2025
All (108) Journal Article (97) Book Chapter (3) Conference Publication (3) Other Outputs (5)

41 - 60 of 108 works

2021

Journal Article

Clinical translation of silica nanoparticles

Janjua, Taskeen Iqbal, Cao, Yuxue, Yu, Chengzhong and Popat, Amirali (2021). Clinical translation of silica nanoparticles. Nature Reviews Materials, 6 (12), 1-3. doi: 10.1038/s41578-021-00385-x

Clinical translation of silica nanoparticles

2021

Journal Article

Nanocarriers for oral delivery of biologics: small carriers for big payloads

Cao, Yuxue, Rewatkar, Prarthana, Wang, Ran, Hasnain, Sumaira Z., Popat, Amirali and Kumeria, Tushar (2021). Nanocarriers for oral delivery of biologics: small carriers for big payloads. Trends in Pharmacological Sciences, 42 (11), 957-972. doi: 10.1016/j.tips.2021.08.005

Nanocarriers for oral delivery of biologics: small carriers for big payloads

2021

Journal Article

Mesoporous silica nanoparticles improve oral delivery of antitubercular bicyclic nitroimidazoles

Ang, Chee Wei, Tan, Lendl, Qu, Zhi, West, Nicholas P., Cooper, Matthew A., Popat, Amirali and Blaskovich, Mark A.T. (2021). Mesoporous silica nanoparticles improve oral delivery of antitubercular bicyclic nitroimidazoles. ACS Biomaterials Science and Engineering, 8 (10) acsbiomaterials.1c00807, 4196-4206. doi: 10.1021/acsbiomaterials.1c00807

Mesoporous silica nanoparticles improve oral delivery of antitubercular bicyclic nitroimidazoles

2021

Other Outputs

Formulation and treatment methods

Florin, Timothy, Popat, Amirali and Jambhrunkar, Siddharth (2021). Formulation and treatment methods. US11077112B2.

Formulation and treatment methods

2021

Journal Article

Over the counter low-dose cannabidiol: a viewpoint from the ACRE Capacity Building Group

Hallinan, Christine Mary, Eden, Edward, Graham, Myfanwy, Greenwood, Lisa-Marie, Mills, Jessica, Popat, Amirali, Truong, Linda and Bonomo, Yvonne (2021). Over the counter low-dose cannabidiol: a viewpoint from the ACRE Capacity Building Group. Journal of Psychopharmacology, 36 (6) 02698811211035394, 2698811211035394-665. doi: 10.1177/02698811211035394

Over the counter low-dose cannabidiol: a viewpoint from the ACRE Capacity Building Group

2021

Journal Article

Extracellular vesicle nanoarchitectonics for novel drug delivery applications

Sharma, Shayna, Masud, Mostafa Kamal, Kaneti, Yusuf Valentino, Rewatkar, Prarthana, Koradia, Aayushi, Hossain, Md. Shahriar A., Yamauchi, Yusuke, Popat, Amirali and Salomon, Carlos (2021). Extracellular vesicle nanoarchitectonics for novel drug delivery applications. Small, 17 (42) 2102220, 1-22. doi: 10.1002/smll.202102220

Extracellular vesicle nanoarchitectonics for novel drug delivery applications

2021

Journal Article

pH – responsive colloidal carriers assembled from β-lactoglobulin and epsilon poly-l-lysine for oral drug delivery

Pujara, Naisarg, Giri, Rabina, Yau Wong, Kuan, Qu, Zhi, Rewatkar, Prarthana, Moniruzzaman, Md., Begun, Jakob, Ross, Benjamin P., McGuckin, Michael and Popat, Amirali (2021). pH – responsive colloidal carriers assembled from β-lactoglobulin and epsilon poly-l-lysine for oral drug delivery. Journal of Colloid and Interface Science, 589, 45-55. doi: 10.1016/j.jcis.2020.12.054

pH – responsive colloidal carriers assembled from β-lactoglobulin and epsilon poly-l-lysine for oral drug delivery

2021

Journal Article

Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery

Raza, Aun, Alavi, Seyed Ebrahim, Sime, Fekade Bruck, Han, Felicity Y., Roberts, Jason A., Popat, Amirali, Falconer, James R. and Kumeria, Tushar (2021). Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery. Acta Biomaterialia, 126, 277-290. doi: 10.1016/j.actbio.2021.03.042

Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery

2021

Journal Article

Sustained release ketamine-loaded porous silicon-PLGA microparticles prepared by an optimized supercritical CO2 process

Xu, Weizhi, Zhao, Zonglan, Falconer, James, Whittaker, Andrew K., Popat, Amirali, Smith, Maree T., Kumeria, Tushar and Han, Felicity Y. (2021). Sustained release ketamine-loaded porous silicon-PLGA microparticles prepared by an optimized supercritical CO2 process. Drug Delivery and Translational Research, 12 (3), 676-694. doi: 10.1007/s13346-021-00991-w

Sustained release ketamine-loaded porous silicon-PLGA microparticles prepared by an optimized supercritical CO2 process

2021

Journal Article

Frontiers in the treatment of glioblastoma: past, present and emerging

Janjua, Taskeen Iqbal, Rewatkar, Prarthana, Ahmed-Cox, Aria, Saeed, Iqira, Mansfeld, Friederike M., Kulshreshtha, Ritu, Kumeria, Tushar, Ziegler, David S., Kavallaris, Maria, Mazzieri, Roberta and Popat, Amirali (2021). Frontiers in the treatment of glioblastoma: past, present and emerging. Advanced Drug Delivery Reviews, 171, 108-138. doi: 10.1016/j.addr.2021.01.012

Frontiers in the treatment of glioblastoma: past, present and emerging

2021

Journal Article

PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery

Raza, Aun, Miles, Jared A., Bruck Sime, Fekade, Ross, Benjamin P., Roberts, Jason A., Popat, Amirali, Kumeria, Tushar and Falconer, James R. (2021). PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery. International Journal of Pharmaceutics, 597 120280, 120280. doi: 10.1016/j.ijpharm.2021.120280

PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery

2021

Journal Article

Supercritical carbon dioxide assisted complexation of benznidazole: γ-cyclodextrin for improved dissolution

Ndayishimiye, John, Popat, Amirali, Kumeria, Tushar, Blaskovich, Mark A.T. and Falconer, James Robert (2021). Supercritical carbon dioxide assisted complexation of benznidazole: γ-cyclodextrin for improved dissolution. International Journal of Pharmaceutics, 596 120240, 120240. doi: 10.1016/j.ijpharm.2021.120240

Supercritical carbon dioxide assisted complexation of benznidazole: γ-cyclodextrin for improved dissolution

2021

Journal Article

Protein nanoparticles for enhanced oral delivery of coenzyme-Q10: in vitro and in silico studies

Banun, Vanessa Jane, Rewatkar, Prarthana, Chaudhary, Zanib, Qu, Zhi, Janjua, Taskeen, Patil, Anuja, Wu, Yuao, Ta, Hang T., Bansal, Nidhi, Miles, Jared A., Ross, Benjamin P., Kumeria, Tushar and Popat, Amirali (2021). Protein nanoparticles for enhanced oral delivery of coenzyme-Q10: in vitro and in silico studies. ACS Biomaterials Science and Engineering, 9 (6) acsbiomaterials.0c01354, 2846-2856. doi: 10.1021/acsbiomaterials.0c01354

Protein nanoparticles for enhanced oral delivery of coenzyme-Q10: in vitro and in silico studies

2021

Journal Article

Emerging nanomedicines for the treatment of atopic dermatitis

Parekh, Khushali, Mehta, Tejal A., Dhas, Namdev, Kumar, Pavan and Popat, Amirali (2021). Emerging nanomedicines for the treatment of atopic dermatitis. AAPS PharmSciTech, 22 (2) 55, 55. doi: 10.1208/s12249-021-01920-3

Emerging nanomedicines for the treatment of atopic dermatitis

2021

Journal Article

Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenem

Raza, Aun, Sime, Fekade Bruck, Cabot, Peter J., Roberts, Jason A., Falconer, James R., Kumeria, Tushar and Popat, Amirali (2021). Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenem. ACS Biomaterials Science and Engineering, 7 (5) acsbiomaterials.0c01284, 1836-1853. doi: 10.1021/acsbiomaterials.0c01284

Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenem

2021

Journal Article

Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma

Janjua, Taskeen Iqbal, Ahmed-Cox, Aria, Meka, Anand Kumar, Mansfeld, Friederike M., Forgham, Helen, Ignacio, Rosa Mistica C., Cao, Yuxue, McCarroll, Joshua A., Mazzieri, Roberta, Kavallaris, Maria and Popat, Amirali (2021). Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma. Nanoscale, 13 (40), 16909-16922. doi: 10.1039/d1nr03553c

Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma

2021

Journal Article

Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin

Ndayishimiye, John, Cao, Yuxue, Kumeria, Tushar, Blaskovich, Mark A. T., Falconer, James Robert and Popat, Amirali (2021). Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin. Journal of Materials Chemistry B, 9 (35), 7145-7166. doi: 10.1039/d1tb01430g

Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin

2021

Journal Article

Rapid fabrication of homogeneously distributed hyper-branched gold nanostructured electrode based electrochemical immunosensor for detection of protein biomarkers

Bakshi, Shrishty, Mehta, Samriddhi, Kumeria, Tushar, Shiddiky, Muhammad J.A., Popat, Amirali, Choudhury, Sangeeta, Bose, Sudeep and Nayak, Ranu (2021). Rapid fabrication of homogeneously distributed hyper-branched gold nanostructured electrode based electrochemical immunosensor for detection of protein biomarkers. Sensors and Actuators, B: Chemical, 326 128803, 128803. doi: 10.1016/j.snb.2020.128803

Rapid fabrication of homogeneously distributed hyper-branched gold nanostructured electrode based electrochemical immunosensor for detection of protein biomarkers

2020

Journal Article

Oral meropenem for superbugs: challenges and opportunities

Raza, Aun, Ngieng, Shih Chen, Sime, Fekade Bruck, Cabot, Peter J., Roberts, Jason A., Popat, Amirali, Kumeria, Tushar and Falconer, James R. (2020). Oral meropenem for superbugs: challenges and opportunities. Drug Discovery Today, 26 (2), 551-560. doi: 10.1016/j.drudis.2020.11.004

Oral meropenem for superbugs: challenges and opportunities

2020

Journal Article

One‐pot synthesis of pH‐responsive eudragit‐mesoporous silica nanocomposites enable colonic delivery of glucocorticoids for the treatment of inflammatory bowel disease

Qu, Zhi, Wong, Kuan Yau, Moniruzzaman, Md., Begun, Jakob, Santos, Hélder A, Hasnain, Sumaira Z., Kumeria, Tushar, McGuckin, Michael A. and Popat, Amirali (2020). One‐pot synthesis of pH‐responsive eudragit‐mesoporous silica nanocomposites enable colonic delivery of glucocorticoids for the treatment of inflammatory bowel disease. Advanced Therapeutics, 4 (2) 2000165, 2000165. doi: 10.1002/adtp.202000165

One‐pot synthesis of pH‐responsive eudragit‐mesoporous silica nanocomposites enable colonic delivery of glucocorticoids for the treatment of inflammatory bowel disease

Current funding

  • 2024 - 2025
    Targeting brain tumour using rationally designed nanomedicine
    Brain Foundation Research Grant
    Open grant
  • 2023 - 2028
    ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance (ARC CEA-StAR)
    ARC Industrial Transformation Training Centres
    Open grant
  • 2020 - 2025
    Ovarian cancer early detection, monitoring and therapeutic intervention using extracellular vesicles
    NHMRC MRFF EPCDR - Ovarian Cancer Research
    Open grant

Past funding

  • 2024 - 2025
    Ultrasmall nanoparticles for overcoming biological barriers in the treatment of Glioblastoma
    Cure Cancer Early Career Research Grants
    Open grant
  • 2023 - 2024
    Overcome biological barriers in cancer for the treatment of glioblastoma using personalised nanomedicine
    TdC Pioneering Grant
    Open grant
  • 2023
    Compounding Personalised Medicines using 3D Printing
    UQ Knowledge Exchange & Translation Fund
    Open grant
  • 2021 - 2024
    Innovative delivery methods for the biologic soluble RAGE to prevent Type 1 Diabetes
    JDRF Pilot and Innovation Awards
    Open grant
  • 2019
    Enhanced osseointegration on growth factor releasing anodized 3D printed titanium dental implants with titania nanotubes
    Australian Dental Research Fund Inc
    Open grant
  • 2019 - 2021
    Parameters controlling naonparticle biodistribution upon oral administration under inflammatory conditions (Siloral)
    DAAD - German Academic Exchange Service
    Open grant
  • 2018 - 2020
    Encapsulation of plant extracts formulation using variety of protein based nanoparticles (former C03644-001)
    Integria Healthcare (Australia) Pty Ltd
    Open grant
  • 2018 - 2021
    Platform Nanotechnologies for Oral Delivery of Drugs, Therapeutic Protein and Peptide Delivery
    NHMRC Career Development Fellowship
    Open grant
  • 2017 - 2023
    Australian Centre for Cannabinoids and Research Excellence (ACRE): Quality and safety in the implementation of medicinal cannabis use in the community (NHMRC CRE administered by University of Newcastl
    University of Newcastle
    Open grant
  • 2016 - 2018
    HDAC3 as a novel orchestrator of lipid oxidation in the intestine and potential therapeutic target in obesity (NHMRC Project Grant administered by La Trobe University)
    La Trobe University
    Open grant
  • 2015
    Programmable nanoparticles for the treatment of Inflammatory Bowel Disease
    UQ Early Career Researcher
    Open grant
  • 2014 - 2017
    NHMRC Early Career Fellowship (Peter Doherty - Australian Biomedical Fellowship): Bioresponsive nanocarriers for controlled and targeted delivery to efficiently treat Inflamatory Bowel Disease (IBD)
    NHMRC Early Career Fellowships
    Open grant
  • 2014 - 2015
    Nanoencapsulation of bifenthrin for higher stability, efficacy, and controlled release.
    UQ Collaboration and Industry Engagement Fund - Seed Research Grant
    Open grant

Availability

Professor Amirali Popat is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

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