Professor Amirali Popat
Professor

Amirali Popat

Email: 
Phone: 
+61 7 334 61870

Background

Research Interests

  • Advanced Drug Delivery and Nanomedicine 1.Advanced drug delivery methods (controlled release dosage forms such as tablets, granules and microspheres) 2. Biomaterials as next generation adjuvant for vaccine delivery 3. Surface modified nanomaterials (Silica, Polymer, Liposomes) 4. Programmable nanoparticales for oral drug delivery and targeting 5. Translocation of nanoparticles after oral drug delivery (In-vitro and In-vivo)

Qualifications

  • Master of Pharmaceutical Science, Gujarat University
  • Bachelor of Pharmacy, Gujarat University

Availability

Professor Amirali Popat is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Chemical Sciences Inorganic chemistry Nanobiotechnology Nanomaterials Nanomedicine Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Pharmacy, Gujarat University
  • Masters (Research), Gujarat University

Research interests

  • Advanced Drug Delivery and Nanomedicine

    1.Advanced drug delivery methods (controlled release dosage forms such as tablets, granules and microspheres) 2. Biomaterials as next generation adjuvant for vaccine delivery 3. Surface modified nanomaterials (Silica, Polymer, Liposomes) 4. Programmable nanoparticales for oral drug delivery and targeting 5. Translocation of nanoparticles after oral drug delivery (In-vitro and In-vivo)

Search Professor Amirali Popat’s works on UQ eSpace

108 works between 2011 and 2025
All (108) Journal Article (97) Book Chapter (3) Conference Publication (3) Other Outputs (5)

21 - 40 of 108 works

2023

Journal Article

Influence of pore size and surface functionalization of mesoporous silica nanoparticles on the solubility and antioxidant activity of confined coenzyme Q10

Meka, Anand Kumar, Gopalakrishna, Akshatha, Iriarte-Mesa, Claudia, Rewatkar, Prarthana, Qu, Zhi, Wu, Xiaoxin, Cao, Yuxue, Prasadam, Indira, Janjua, Taskeen Iqbal, Kleitz, Freddy, Kumeria, Tushar and Popat, Amirali (2023). Influence of pore size and surface functionalization of mesoporous silica nanoparticles on the solubility and antioxidant activity of confined coenzyme Q10. Molecular Pharmaceutics, 20 (6), 2966-2977. doi: 10.1021/acs.molpharmaceut.3c00017

Influence of pore size and surface functionalization of mesoporous silica nanoparticles on the solubility and antioxidant activity of confined coenzyme Q10

2023

Journal Article

Virus-like silica nanoparticles enhance macromolecule permeation in vivo

Cao, Yuxue, Janjua, Taskeen Iqbal, Qu, Zhi, Draphoen, Bastian, Bai, Yunfan, Linden, Mika, Moniruzzaman, Md., Hasnain, Sumaira Z., Kumeria, Tushar and Popat, Amirali (2023). Virus-like silica nanoparticles enhance macromolecule permeation in vivo. Biomaterials Science, 11 (13), 4508-4521. doi: 10.1039/d3bm00137g

Virus-like silica nanoparticles enhance macromolecule permeation in vivo

2023

Journal Article

Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma

Janjua, Taskeen Iqbal, Cao, Yuxue, Ahmed-Cox, Aria, Raza, Aun, Moniruzzaman, Md, Akhter, Dewan Taslima, Fletcher, Nicholas L., Kavallaris, Maria, Thurecht, Kristofer J. and Popat, Amirali (2023). Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma. Journal of Controlled Release, 357, 161-174. doi: 10.1016/j.jconrel.2023.03.040

Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma

2023

Journal Article

Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides

Alharthi, Sitah, Popat, Amirali, Ziora, Zyta Maria and Moyle, Peter Michael (2023). Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides. Molecules, 28 (5) 2114, 1-17. doi: 10.3390/molecules28052114

Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides

2023

Conference Publication

Enhancing the efficacy of cannabidiol using protein nanoparticles to treat inflammatory bowel disease

Moniruzzaman, M., Rewatkar, P., Begun, J. and Popat, A. (2023). Enhancing the efficacy of cannabidiol using protein nanoparticles to treat inflammatory bowel disease. 18th Congress of ECCO, Copenhagen, Denmark, 1-4 March 2023. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjac190.0167

Enhancing the efficacy of cannabidiol using protein nanoparticles to treat inflammatory bowel disease

2023

Book Chapter

3D Printing for Novel Dosage Form Design

Krueger, Liam, Miles, Jared A. and Popat, Amirali (2023). 3D Printing for Novel Dosage Form Design. 3D & 4D Printing Methods for Pharmaceutical Manufacturing and Personalised Drug Delivery Opportunities and Challenges. (pp. 25-44) Cham, Switzerland: Springer. doi: 10.1007/978-3-031-34119-9_2

3D Printing for Novel Dosage Form Design

2022

Journal Article

Spray nebulization enables polycaprolactone nanofiber production in a manner suitable for generation of scaffolds or direct deposition of nanofibers onto cells

McKenna, Eamonn, Futrega, Kathryn, Klein, Travis J, Altalhi, Tariq A., Popat, Amirali, Kumeria, Tushar and Doran, Michael Robert (2022). Spray nebulization enables polycaprolactone nanofiber production in a manner suitable for generation of scaffolds or direct deposition of nanofibers onto cells. Biofabrication, 15 (2) 025003, 1-12. doi: 10.1088/1758-5090/aca5b7

Spray nebulization enables polycaprolactone nanofiber production in a manner suitable for generation of scaffolds or direct deposition of nanofibers onto cells

2022

Journal Article

3D printing hybrid materials using fused deposition modelling for solid oral dosage forms

Krueger, Liam, Miles, Jared A. and Popat, Amirali (2022). 3D printing hybrid materials using fused deposition modelling for solid oral dosage forms. Journal of Controlled Release, 351, 444-455. doi: 10.1016/j.jconrel.2022.09.032

3D printing hybrid materials using fused deposition modelling for solid oral dosage forms

2022

Journal Article

Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy

Raza, Aun, Rossi, Gustavo Rodrigues, Janjua, Taskeen Iqbal, Souza-Fonseca-Guimaraes, Fernando and Popat, Amirali (2022). Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy. Trends in Biotechnology, 41 (1), 77-92. doi: 10.1016/j.tibtech.2022.06.011

Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy

2022

Journal Article

Ultra-bright green carbon dots with excitation-independent fluorescence for bioimaging

Singh, Amandeep, Qu, Zhi, Sharma, Astha, Singh, Mandeep, Tse, Brian, Ostrikov, Kostya, Popat, Amirali, Sonar, Prashant and Kumeria, Tushar (2022). Ultra-bright green carbon dots with excitation-independent fluorescence for bioimaging. Journal of Nanostructure in Chemistry, 13 (3), 1-11. doi: 10.1007/s40097-022-00501-5

Ultra-bright green carbon dots with excitation-independent fluorescence for bioimaging

2022

Journal Article

Formulation and biological evaluation of mesoporous silica nanoparticles loaded with combinations of sortase A inhibitors and antimicrobial peptides

Alharthi, Sitah, Ziora, Zyta M., Janjua, Taskeen, Popat, Amirali and Moyle, Peter M. (2022). Formulation and biological evaluation of mesoporous silica nanoparticles loaded with combinations of sortase A inhibitors and antimicrobial peptides. Pharmaceutics, 14 (5) 986, 986. doi: 10.3390/pharmaceutics14050986

Formulation and biological evaluation of mesoporous silica nanoparticles loaded with combinations of sortase A inhibitors and antimicrobial peptides

2022

Journal Article

Nanomaterials: the new antimicrobial magic bullet

Ndayishimiye, John, Kumeria, Tushar, Popat, Amirali, Falconer, James Robert and Blaskovich, Mark A. T. (2022). Nanomaterials: the new antimicrobial magic bullet. ACS Infectious Diseases, 8 (4), 693-712. doi: 10.1021/acsinfecdis.1c00660

Nanomaterials: the new antimicrobial magic bullet

2022

Journal Article

Understanding the relationship between solubility and permeability of γ-cyclodextrin-based systems embedded with poorly aqueous soluble benznidazole

Ndayishimiye, John, Kumeria, Tushar, Popat, Amirali, Blaskovich, Mark A.T. and Falconer, James Robert (2022). Understanding the relationship between solubility and permeability of γ-cyclodextrin-based systems embedded with poorly aqueous soluble benznidazole. International Journal of Pharmaceutics, 616 121487, 121487. doi: 10.1016/j.ijpharm.2022.121487

Understanding the relationship between solubility and permeability of γ-cyclodextrin-based systems embedded with poorly aqueous soluble benznidazole

2022

Journal Article

Influence of PEGylated porous silicon nanoparticles on permeation and efflux of an orally administered antibiotic

Raza, A., Kamato, D., Sime, F.B., Roberts, J.A., Popat, A., Falconer, J.R. and Kumeria, T. (2022). Influence of PEGylated porous silicon nanoparticles on permeation and efflux of an orally administered antibiotic. Materials Today Advances, 13 100210, 100210. doi: 10.1016/j.mtadv.2022.100210

Influence of PEGylated porous silicon nanoparticles on permeation and efflux of an orally administered antibiotic

2022

Journal Article

3D printing: potential clinical applications for personalised solid dose medications

Krueger, Liam, Miles, Jared A., Steadman, Kathryn J., Kumeria, Tushar, Freeman, Christopher R. and Popat, Amirali (2022). 3D printing: potential clinical applications for personalised solid dose medications. Medical Journal of Australia, 216 (2), 64-67. doi: 10.5694/mja2.51381

3D printing: potential clinical applications for personalised solid dose medications

2022

Journal Article

Spray‐n‐Sense: sprayable nanofibers for on‐site chemical sensing

Bakshi, Shrishty, Snoswell, Aaron J., Kwok, Kei Yeung, Cheng, Lung Hei, Altalhi, Tariq A., Santos, Abel, Popat, Amirali and Kumeria, Tushar (2022). Spray‐n‐Sense: sprayable nanofibers for on‐site chemical sensing. Advanced Functional Materials, 32 (16) 2103496, 2103496. doi: 10.1002/adfm.202103496

Spray‐n‐Sense: sprayable nanofibers for on‐site chemical sensing

2021

Other Outputs

Novel formulation and treatment methods

Florin, Timothy, Popat, Amirali and Jambhrunkar, Siddharth (2021). Novel formulation and treatment methods. US20210393638A1.

Novel formulation and treatment methods

2021

Journal Article

Tacrolimus encapsulated mesoporous silica nanoparticles embedded hydrogel for the treatment of atopic dermatitis

Parekh, Khushali, Hariharan, Kartik, Qu, Zhi, Rewatkar, Prarthana, Cao, Yuxue, Moniruzzaman, Md., Pandey, Preeti, Popat, Amirali and Mehta, Tejal (2021). Tacrolimus encapsulated mesoporous silica nanoparticles embedded hydrogel for the treatment of atopic dermatitis. International Journal of Pharmaceutics, 608 121079, 121079. doi: 10.1016/j.ijpharm.2021.121079

Tacrolimus encapsulated mesoporous silica nanoparticles embedded hydrogel for the treatment of atopic dermatitis

2021

Journal Article

Facile synthesis of dendrimer like mesoporous silica nanoparticles to enhance targeted delivery of interleukin-22

Elshaer, Dana, Moniruzzaman, Md., Ong, Yi Theng, Qu, Zhi, Schreiber, Veronika, Begun, Jakob and Popat, Amirali (2021). Facile synthesis of dendrimer like mesoporous silica nanoparticles to enhance targeted delivery of interleukin-22. Biomaterials Science, 9 (22), 7402-7411. doi: 10.1039/d1bm01352a

Facile synthesis of dendrimer like mesoporous silica nanoparticles to enhance targeted delivery of interleukin-22

2021

Journal Article

Enhanced Mucosal Transport of Polysaccharide–Calcium Phosphate Nanocomposites for Oral Vaccination

Cao, Pei, Wang, Jingjing, Sun, Bing, Rewatkar, Prarthana, Popat, Amirali, Fu, Changkui, Peng, Hui, Xu, Zhi Ping and Li, Li (2021). Enhanced Mucosal Transport of Polysaccharide–Calcium Phosphate Nanocomposites for Oral Vaccination. ACS Applied Bio Materials, 4 (11) acsabm.1c00798, 7865-7878. doi: 10.1021/acsabm.1c00798

Enhanced Mucosal Transport of Polysaccharide–Calcium Phosphate Nanocomposites for Oral Vaccination

Current funding

  • 2024 - 2025
    Targeting brain tumour using rationally designed nanomedicine
    Brain Foundation Research Grant
    Open grant
  • 2023 - 2028
    ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance (ARC CEA-StAR)
    ARC Industrial Transformation Training Centres
    Open grant
  • 2020 - 2025
    Ovarian cancer early detection, monitoring and therapeutic intervention using extracellular vesicles
    NHMRC MRFF EPCDR - Ovarian Cancer Research
    Open grant

Past funding

  • 2024 - 2025
    Ultrasmall nanoparticles for overcoming biological barriers in the treatment of Glioblastoma
    Cure Cancer Early Career Research Grants
    Open grant
  • 2023 - 2024
    Overcome biological barriers in cancer for the treatment of glioblastoma using personalised nanomedicine
    TdC Pioneering Grant
    Open grant
  • 2023
    Compounding Personalised Medicines using 3D Printing
    UQ Knowledge Exchange & Translation Fund
    Open grant
  • 2021 - 2024
    Innovative delivery methods for the biologic soluble RAGE to prevent Type 1 Diabetes
    JDRF Pilot and Innovation Awards
    Open grant
  • 2019
    Enhanced osseointegration on growth factor releasing anodized 3D printed titanium dental implants with titania nanotubes
    Australian Dental Research Fund Inc
    Open grant
  • 2019 - 2021
    Parameters controlling naonparticle biodistribution upon oral administration under inflammatory conditions (Siloral)
    DAAD - German Academic Exchange Service
    Open grant
  • 2018 - 2020
    Encapsulation of plant extracts formulation using variety of protein based nanoparticles (former C03644-001)
    Integria Healthcare (Australia) Pty Ltd
    Open grant
  • 2018 - 2021
    Platform Nanotechnologies for Oral Delivery of Drugs, Therapeutic Protein and Peptide Delivery
    NHMRC Career Development Fellowship
    Open grant
  • 2017 - 2023
    Australian Centre for Cannabinoids and Research Excellence (ACRE): Quality and safety in the implementation of medicinal cannabis use in the community (NHMRC CRE administered by University of Newcastl
    University of Newcastle
    Open grant
  • 2016 - 2018
    HDAC3 as a novel orchestrator of lipid oxidation in the intestine and potential therapeutic target in obesity (NHMRC Project Grant administered by La Trobe University)
    La Trobe University
    Open grant
  • 2015
    Programmable nanoparticles for the treatment of Inflammatory Bowel Disease
    UQ Early Career Researcher
    Open grant
  • 2014 - 2017
    NHMRC Early Career Fellowship (Peter Doherty - Australian Biomedical Fellowship): Bioresponsive nanocarriers for controlled and targeted delivery to efficiently treat Inflamatory Bowel Disease (IBD)
    NHMRC Early Career Fellowships
    Open grant
  • 2014 - 2015
    Nanoencapsulation of bifenthrin for higher stability, efficacy, and controlled release.
    UQ Collaboration and Industry Engagement Fund - Seed Research Grant
    Open grant

Availability

Professor Amirali Popat is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Enquiries

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